Compile Data Set for Download or QSAR
Found 14 with Last Name = 'fowler' and Initial = 'js'
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI [9-251](Staphylococcus aureus)
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM97445(PT119)copy SMILEScopy InChI
Affinity DataKi:  0.0100nMAssay Description:Inhibition of Staphylococcus aureus enoyl ACP reductaseMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50401014(CHEMBL2206307)copy SMILEScopy InChI
Affinity DataKi:  8nMAssay Description:Binding affinity to DATMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1N2DPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50296249((1R,2S,3S,5S)-methyl 8-(4-fluorobut-2-ynyl)-3-p-to...)copy SMILEScopy InChI
Affinity DataIC50: 1.93nMAssay Description:Displacement of [3H]WIN35,428 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1N2DPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50296249((1R,2S,3S,5S)-methyl 8-(4-fluorobut-2-ynyl)-3-p-to...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27081HZPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50296249((1R,2S,3S,5S)-methyl 8-(4-fluorobut-2-ynyl)-3-p-to...)copy SMILEScopy InChI
Affinity DataIC50: 3.26nMAssay Description:Displacement of [3H]DA from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1N2DPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Chonbuk National University

Curated by ChEMBL
LigandPNGBDBM50114826(8-(4-Methoxy-phenyl)-8-oxo-octanoic acid hydroxyam...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P2722WPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50296249((1R,2S,3S,5S)-methyl 8-(4-fluorobut-2-ynyl)-3-p-to...)copy SMILEScopy InChI
Affinity DataIC50: 22.5nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1N2DPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50296249((1R,2S,3S,5S)-methyl 8-(4-fluorobut-2-ynyl)-3-p-to...)copy SMILEScopy InChI
Affinity DataIC50: 31.0nMAssay Description:Displacement of [3H]NE from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1N2DPubMed
TargetAmine oxidase [flavin-containing] A/B(Homo sapiens (Human))
Brookhaven National Laboratory

Curated by ChEMBL
LigandPNGBDBM50228339(CHEMBL58177)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:In vitro inhibitory activity against Monoamine oxidase in baboon brain was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4DFKPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50296249((1R,2S,3S,5S)-methyl 8-(4-fluorobut-2-ynyl)-3-p-to...)copy SMILEScopy InChI
Affinity DataIC50: 108nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1N2DPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50296249((1R,2S,3S,5S)-methyl 8-(4-fluorobut-2-ynyl)-3-p-to...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Displacement of [3H]5-HT from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1N2DPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Brookhaven National Laboratory

Curated by ChEMBL
LigandPNGBDBM50006543(3-(2-Iodo-benzoyloxy)-8-methyl-8-aza-bicyclo[3.2.1...)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Concentration of the compound inhibiting [3H]-Cocaine binding site to rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8K00PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Brookhaven National Laboratory

Curated by ChEMBL
LigandPNGBDBM50296782((1R,2S,3S,5S)-methyl 8-((E)-3-iodoallyl)-3-p-tolyl...)copy SMILEScopy InChI
Affinity DataKd:  4nMAssay Description:Binding affinity to rat DATMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1N2DPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Brookhaven National Laboratory

Curated by ChEMBL
LigandPNGBDBM50401015(CHEMBL1947086)copy SMILEScopy InChI
Affinity DataKd:  9nMAssay Description:Binding affinity to rat DATMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1N2DPubMed