Target5-hydroxytryptamine receptor 1A/2C(Homo sapiens (Human))
The Trustees of Columbia University in the City of New York
US Patent
The Trustees of Columbia University in the City of New York
US Patent
Affinity DataKi: 0.150nM ΔG°: -52.1kJ/molepH: 7.4 T: 2°CAssay Description:Preparation of Membrane Fractions from CHO-h5-HT1A Cells. Membranes from CHO cells stably expressing the human 5-HT1A receptor at a density of 8 pmol...More data for this Ligand-Target Pair
Affinity DataKi: 0.150nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1AR (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1AR (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.440nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1AR (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.460nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1AR (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.660nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1AR (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Columbia University Medical Center
Curated by ChEMBL
Columbia University Medical Center
Curated by ChEMBL
Affinity DataKi: 0.776nMAssay Description:Displacement of [125I]SB-258585 from human recombinant 5HT6 receptor using methiothepin after 45 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1AR (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.835nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1AR (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Agonist activity assessed by stimulation of [35S]GTP-gamma-S binding to human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1AR (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1AR (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1AR (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]rauwolscine from adrenergic alpha2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1AR (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1AR (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1AR (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1AR (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1AR (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A/2C(Homo sapiens (Human))
The Trustees of Columbia University in the City of New York
US Patent
The Trustees of Columbia University in the City of New York
US Patent
Affinity DataKi: 4nM ΔG°: -44.6kJ/molepH: 7.4 T: 2°CAssay Description:Preparation of Membrane Fractions from CHO-h5-HT1A Cells. Membranes from CHO cells stably expressing the human 5-HT1A receptor at a density of 8 pmol...More data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Displacement of [3H]rauwolscine from adrenergic alpha2C receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4.80nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1AR (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A/2C(Homo sapiens (Human))
The Trustees of Columbia University in the City of New York
US Patent
The Trustees of Columbia University in the City of New York
US Patent
Affinity DataKi: 5.5nM ΔG°: -43.8kJ/molepH: 7.4 T: 2°CAssay Description:Preparation of Membrane Fractions from CHO-h5-HT1A Cells. Membranes from CHO cells stably expressing the human 5-HT1A receptor at a density of 8 pmol...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A/2C(Homo sapiens (Human))
The Trustees of Columbia University in the City of New York
US Patent
The Trustees of Columbia University in the City of New York
US Patent
Affinity DataKi: 6nM ΔG°: -43.6kJ/molepH: 7.4 T: 2°CAssay Description:Preparation of Membrane Fractions from CHO-h5-HT1A Cells. Membranes from CHO cells stably expressing the human 5-HT1A receptor at a density of 8 pmol...More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1AR (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 8.5nMAssay Description:Binding affinity to dopamine D4 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 9.10nMAssay Description:Binding affinity to human 5HT7 receptorMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Columbia University
Curated by ChEMBL
Columbia University
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Displacement of [3H]paroxetine from 5HTT receptorMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 22nMAssay Description:Binding affinity to dopamine D2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Binding affinity to adrenergic alpha-2C receptorMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1AR (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 32nMAssay Description:Binding affinity to adrenergic alpha-1 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 34nMAssay Description:Binding affinity to 5HT2B receptor by radioligand binding assayMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 37nMAssay Description:Binding affinity to dopamine 2 receptor (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 42nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A/2C(Homo sapiens (Human))
The Trustees of Columbia University in the City of New York
US Patent
The Trustees of Columbia University in the City of New York
US Patent
Affinity DataKi: 58.3nM ΔG°: -38.4kJ/molepH: 7.4 T: 2°CAssay Description:Preparation of Membrane Fractions from CHO-h5-HT1A Cells. Membranes from CHO cells stably expressing the human 5-HT1A receptor at a density of 8 pmol...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Columbia University Medical Center
Curated by ChEMBL
Columbia University Medical Center
Curated by ChEMBL
Affinity DataKi: 59nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 59nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1AR (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 61nMAssay Description:Binding affinity to adrenergic beta-2 receptorMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 63nMAssay Description:Binding affinity to dopamine D3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 68nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1AR (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine 1D receptor(Bos taurus (Bovine))
Columbia University
Curated by PDSP Ki Database
Columbia University
Curated by PDSP Ki Database
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