Compile Data Set for Download or QSAR
Found 256 with Last Name = 'beckley' and Initial = 'jt'
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM50451447(CHEMBL4217988)copy SMILEScopy InChI
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 9 subunit alpha(Mus musculus)
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM50451447(CHEMBL4217988)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Inhibition of mouse Nav1.7 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM145285(US8952169, 64 | US9771376, Example 64)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM145591(US8952169, 389)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM50051073(CHEMBL3318132)copy SMILES
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM50505258(CHEMBL4588728)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM190233(US9174999, Table 1, Compound 1)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human Nav1.2 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM190233(US9174999, Table 1, Compound 1)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human Nav1.6 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 9 subunit alpha(Rattus norvegicus)
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM50505258(CHEMBL4588728)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of rat Nav1.7 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM190233(US9174999, Table 1, Compound 1)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF3151PubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM145591(US8952169, 389)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human Nav1.2 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50595859(CHEMBL5192731)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF3151PubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50595862(CHEMBL5189924)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF3151PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50595862(CHEMBL5189924)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF3151PubMed
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM50077471(CHEMBL3416886)copy SMILES
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 9 subunit alpha(Mus musculus)
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM145591(US8952169, 389)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibition of mouse Nav1.7 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM50344821(10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diaz...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human Nav1.6 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM190233(US9174999, Table 1, Compound 1)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human Nav1.1 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM50451447(CHEMBL4217988)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human Nav1.2 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50595859(CHEMBL5192731)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF3151PubMed
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM217483(US9212182, 477 | US9212182, 478)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM217483(US9212182, 477 | US9212182, 478)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 9 subunit alpha(Rattus norvegicus)
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM145591(US8952169, 389)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMAssay Description:Inhibition of rat Nav1.7 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM50344821(10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diaz...)copy SMILEScopy InChI
Affinity DataIC50: 4.10nMAssay Description:Inhibition of human Nav1.1 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 9 subunit alpha(Mus musculus)
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM50505258(CHEMBL4588728)copy SMILEScopy InChI
Affinity DataIC50: 4.40nMAssay Description:Inhibition of mouse Nav1.7 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 3 subunit alpha(Homo sapiens (Human))
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM50344821(10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diaz...)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:Inhibition of human Nav1.3 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM50451447(CHEMBL4217988)copy SMILEScopy InChI
Affinity DataIC50: 5.80nMAssay Description:Inhibition of human Nav1.6 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50595863(CHEMBL5184022)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF3151PubMed
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM145591(US8952169, 389)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human Nav1.1 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50595864(CHEMBL5208387)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF3151PubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50344821(10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diaz...)copy SMILEScopy InChI
Affinity DataIC50: 7.60nMAssay Description:Inhibition of human Nav1.4 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM50505259(CHEMBL4454760)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM50240267(CHEMBL2325014)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM145285(US8952169, 64 | US9771376, Example 64)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human Nav1.1 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 3 subunit alpha(Homo sapiens (Human))
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM190233(US9174999, Table 1, Compound 1)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human Nav1.3 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM50344821(10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diaz...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of human Nav1.2 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50595863(CHEMBL5184022)copy SMILES
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF3151PubMed
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM50051073(CHEMBL3318132)copy SMILES
Affinity DataIC50: 16nMAssay Description:Inhibition of human Nav1.1 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 9 subunit alpha(Mus musculus)
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM217483(US9212182, 477 | US9212182, 478)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of mouse Nav1.7 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 9 subunit alpha(Mus musculus)
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM217483(US9212182, 477 | US9212182, 478)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of mouse Nav1.7 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50505256(CHEMBL4547737)copy SMILEScopy InChI
Affinity DataIC50: 18nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF3151PubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM190233(US9174999, Table 1, Compound 1)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of human Nav1.4 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM50505256(CHEMBL4547737)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM145285(US8952169, 64 | US9771376, Example 64)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human Nav1.2 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 3 subunit alpha(Homo sapiens (Human))
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM50051073(CHEMBL3318132)copy SMILES
Affinity DataIC50: 25nMAssay Description:Inhibition of human Nav1.3 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM50051073(CHEMBL3318132)copy SMILES
Affinity DataIC50: 32nMAssay Description:Inhibition of human Nav1.6 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50595856(CHEMBL5205795)copy SMILES
Affinity DataIC50: 32nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF3151PubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50595857(CHEMBL5192925)copy SMILES
Affinity DataIC50: 33nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF3151PubMed
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM50344821(10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diaz...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM50505258(CHEMBL4588728)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of human Nav1.1 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
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