Compile Data Set for Download or QSAR
Found 23 with Last Name = 'johnson' and Initial = 'jv'
TargetDihydrofolate reductase(Escherichia coli)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50406007(CHEMBL418293)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Apparent binding affinity of compound in Escherichia coli DHFRChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G73FX0PubMed
TargetDihydrofolate reductase(Escherichia coli)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50406006(CHEMBL418492)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Apparent binding affinity against Dihydrofolate reductase in Escherichia coliChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G73FX0PubMed
TargetDihydrofolate reductase(Escherichia coli)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50406005(CHEMBL60827)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Apparent binding affinity of compound in Escherichia coli DHFRChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G73FX0PubMed
TargetDihydrofolate reductase(Escherichia coli)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50406011(CHEMBL300545)copy SMILEScopy InChI
Affinity DataKi:  0.430nMAssay Description:Apparent binding affinity of compound in Escherichia coli DHFRChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G73FX0PubMed
TargetDihydrofolate reductase(Escherichia coli)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)copy SMILEScopy InChI
Affinity DataKi:  1.30nMAssay Description:Apparent binding affinity against Dihydrofolate reductase in Escherichia coliChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G73FX0PubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042378(2-[4-(3-Amino-1-oxo-1,2,5,6-tetrahydro-benzo[f]qui...)copy SMILEScopy InChI
Affinity DataKi:  2.5nMAssay Description:Inhibition of purified human thymidylate synthase isolated from an E. coli harboring thy A gene cloned from SV40 transformed human fibroblast cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K0739TPubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50040858((S)-2-[4-(3-Methyl-1-oxo-1,2-dihydro-benzo[f]quina...)copy SMILEScopy InChI
Affinity DataKi:  5.5nMAssay Description:Inhibition of purified human thymidylate synthase isolated from an E. coli harboring thy A gene cloned from SV40 transformed human fibroblast cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K0739TPubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042375(2-[4-(3-Methyl-1-oxo-1,2,5,6-tetrahydro-benzo[f]qu...)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:Inhibition of purified human thymidylate synthase isolated from an E. coli harboring thy A gene cloned from SV40 transformed human fibroblast cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K0739TPubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50230985(CHEMBL306705)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Inhibition of purified human thymidylate synthase (TS) isolated from an Escherichia coli harboring a plasmid with thy A gene cloned from SV40 transfo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K0739TPubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042382(2-[4-(3-Amino-1-oxo-1,2,5,6-tetrahydro-benzo[f]qui...)copy SMILEScopy InChI
Affinity DataKi:  57nMAssay Description:Inhibition of purified human thymidylate synthase isolated from an E. coli harboring thy A gene cloned from SV40 transformed human fibroblast cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K0739TPubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042380(2-[4-(3-Amino-8-bromo-1-oxo-1,2,5,6-tetrahydro-ben...)copy SMILEScopy InChI
Affinity DataKi:  79nMAssay Description:Inhibition of purified human thymidylate synthase isolated from an E. coli harboring thy A gene cloned from SV40 transformed human fibroblast cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K0739TPubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50231342(CHEMBL118750)copy SMILEScopy InChI
Affinity DataKi:  100nMAssay Description:Inhibition of purified human thymidylate synthase (TS) isolated from an Escherichia coli harboring a plasmid with thy A gene cloned from SV40 transfo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K0739TPubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042376(2-{[4-(3-Amino-1-oxo-1,2,5,6-tetrahydro-benzo[f]qu...)copy SMILEScopy InChI
Affinity DataKi:  660nMAssay Description:Inhibition of purified human thymidylate synthase isolated from an E. coli harboring thy A gene cloned from SV40 transformed human fibroblast cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K0739TPubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042381(3-Methyl-2H-benzo[f]quinazolin-1-one | CHEMBL41889...)copy SMILEScopy InChI
Affinity DataKi:  5.40E+3nMAssay Description:Inhibition of purified human thymidylate synthase isolated from an E. coli harboring thy A gene cloned from SV40 transformed human fibroblast cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K0739TPubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042383(3-Amino-5,6-dihydro-2H-benzo[f]quinazolin-1-one | ...)copy SMILEScopy InChI
Affinity DataKi:  7.00E+3nMAssay Description:Inhibition of purified human thymidylate synthase isolated from an E. coli harboring thy A gene cloned from SV40 transformed human fibroblast cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K0739TPubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042373(2-[4-(3-Methyl-1-oxo-1,2-dihydro-benzo[f]quinazoli...)copy SMILEScopy InChI
Affinity DataKi:  7.37E+3nMAssay Description:Inhibition of purified human thymidylate synthase isolated from an E. coli harboring thy A gene cloned from SV40 transformed human fibroblast cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K0739TPubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042377(3-Amino-8-bromo-5,6-dihydro-2H-benzo[f]quinazolin-...)copy SMILEScopy InChI
Affinity DataKi:  9.00E+3nMAssay Description:Inhibition of purified human thymidylate synthase isolated from an E. coli harboring thy A gene cloned from SV40 transformed human fibroblast cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K0739TPubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50231341(CHEMBL116508)copy SMILEScopy InChI
Affinity DataKi:  1.64E+4nMAssay Description:Inhibition of purified human thymidylate synthase (TS) isolated from an Escherichia coli harboring a plasmid with thy A gene cloned from SV40 transfo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K0739TPubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042374(2-{Methyl-[4-(3-methyl-1-oxo-1,2,5,6-tetrahydro-be...)copy SMILEScopy InChI
Affinity DataKi:  1.67E+4nMAssay Description:Inhibition of purified human thymidylate synthase isolated from an E. coli harboring thy A gene cloned from SV40 transformed human fibroblast cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K0739TPubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042379(3-Methyl-5,6-dihydro-2H-benzo[f]quinazolin-1-one |...)copy SMILEScopy InChI
Affinity DataKi:  3.56E+4nMAssay Description:Inhibition of purified human thymidylate synthase isolated from an E. coli harboring thy A gene cloned from SV40 transformed human fibroblast cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K0739TPubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044608(3-Amino-8,9-dichloro-5,6-dihydro-2H-benzo[f]quinaz...)copy SMILEScopy InChI
Affinity DataIC50: 2.96E+3nMAssay Description:Tested for inhibition against thymidylate synthase (TS) in humanMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX78HNPubMed
TargetThymidylate synthase(Escherichia coli)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044612(3-Amino-7,9-dimethyl-5,6-dihydro-2H-benzo[f]quinaz...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+4nMAssay Description:Tested for inhibition against thymidylate synthase (TS) in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX78HNPubMed
TargetThymidylate synthase(Escherichia coli)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044614(2-Amino-11,12-dihydro-3H-1,3-diaza-chrysen-4-one |...)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+4nMAssay Description:Tested for inhibition against thymidylate synthase (TS) in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX78HNPubMed