Compile Data Set for Download or QSAR
Found 167 with Last Name = 'morey' and Initial = 'jv'
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50418169(CHEMBL1761516)copy SMILEScopy InChI
Affinity DataIC50: 7.94nMAssay Description:Inhibition of IKK-betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VS3PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50418165(CHEMBL1761512)copy SMILEScopy InChI
Affinity DataIC50: 12.6nMAssay Description:Inhibition of IKK-betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VS3PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50230828(5-(4-fluorophenyl)-2-ureidothiophene-3-carboxamide...)copy SMILEScopy InChI
Affinity DataIC50: 19.9nMAssay Description:Inhibition of IKK-betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VS3PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50418166(CHEMBL1761513)copy SMILEScopy InChI
Affinity DataIC50: 19.9nMAssay Description:Inhibition of IKK-betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VS3PubMed
LigandPNGBDBM27450(5-[5-(3-hydroxypropoxy)-6-methoxy-1H-1,3-benzodiaz...)copy SMILEScopy InChI
Affinity DataIC50: 25nMpH: 7.4 T: 2°CAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ311MPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50418167(CHEMBL1761514)copy SMILEScopy InChI
Affinity DataIC50: 25.1nMAssay Description:Inhibition of IKK-betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VS3PubMed
LigandPNGBDBM27452(5-(5,6-dimethoxy-1H-1,3-benzodiazol-1-yl)-3-[(2-me...)copy SMILEScopy InChI
Affinity DataIC50: 40nMpH: 7.4 T: 2°CAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ311MPubMed
LigandPNGBDBM27449(5-{6-methoxy-5-[2-(morpholin-4-yl)ethoxy]-1H-1,3-b...)copy SMILEScopy InChI
Affinity DataIC50: 50nMpH: 7.4 T: 2°CAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ311MPubMed
LigandPNGBDBM27476(2-amino-5-(pyridin-4-yl)-3-(4-sulfamoylphenyl)benz...)copy SMILEScopy InChI
Affinity DataIC50: 79nMpH: 7.4 T: 2°CAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ289WPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM27467(2-amino-5-(4-chlorophenyl)-3-(4-sulfamoylphenyl)be...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ289WPubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
GSK

LigandPNGBDBM27443(5-(1H-1,3-benzodiazol-1-yl)-3-[(4-methylphenyl)met...)copy SMILEScopy InChI
Affinity DataIC50: 126nMpH: 7.2 T: 2°CAssay Description:The compound inhibitory activity was determined by incubation with purified PLK1 and biotinylated peptide substrate in the presence ATP/[gamma-33P]AT...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ311MPubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
GSK

LigandPNGBDBM27444(5-(5,6-dimethoxy-1H-1,3-benzodiazol-1-yl)-3-[(4-me...)copy SMILEScopy InChI
Affinity DataIC50: 126nMpH: 7.2 T: 2°CAssay Description:The compound inhibitory activity was determined by incubation with purified PLK1 and biotinylated peptide substrate in the presence ATP/[gamma-33P]AT...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ311MPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM27489(2-amino-3-{4-[(2-aminoethyl)sulfamoyl]phenyl}-5-ph...)copy SMILEScopy InChI
Affinity DataIC50: 158nMAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ289WPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM27477(2-amino-5-(4-methanesulfonylphenyl)-3-(4-sulfamoyl...)copy SMILEScopy InChI
Affinity DataIC50: 158nMAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ289WPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50418163(CHEMBL1761510)copy SMILEScopy InChI
Affinity DataIC50: 158nMAssay Description:Inhibition of IKK-betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VS3PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50418165(CHEMBL1761512)copy SMILEScopy InChI
Affinity DataIC50: 158nMAssay Description:Inhibition of IKK-beta in human PBMC assessed as TNF-alpha-induced Nuclear factor-kappa-B nuclear translocationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VS3PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM27466(2-amino-5-(4-fluorophenyl)-3-(4-sulfamoylphenyl)be...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ289WPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM27471(2-amino-5-phenyl-3-(4-sulfamoylphenyl)benzamide | ...)copy SMILEScopy InChI
Affinity DataIC50: 251nMAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ289WPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM27476(2-amino-5-(pyridin-4-yl)-3-(4-sulfamoylphenyl)benz...)copy SMILEScopy InChI
Affinity DataIC50: 251nMAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ289WPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM27490(2-amino-3-{4-[(3-methoxypropyl)sulfamoyl]phenyl}-5...)copy SMILEScopy InChI
Affinity DataIC50: 251nMAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ289WPubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
GSK

LigandPNGBDBM27446(5-(5,6-dimethoxy-1H-1,3-benzodiazol-1-yl)-3-(oxola...)copy SMILEScopy InChI
Affinity DataIC50: 251nMpH: 7.2 T: 2°CAssay Description:The compound inhibitory activity was determined by incubation with purified PLK1 and biotinylated peptide substrate in the presence ATP/[gamma-33P]AT...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ311MPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM27492(2-amino-5-phenyl-3-(4-{[2-(pyrrolidin-1-yl)ethyl]s...)copy SMILEScopy InChI
Affinity DataIC50: 251nMAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ289WPubMed
LigandPNGBDBM27448(5-(5,6-dimethoxy-1H-1,3-benzodiazol-1-yl)-3-{[2-(t...)copy SMILEScopy InChI
Affinity DataIC50: 251nMpH: 7.4 T: 2°CAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ311MPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM27491(2-amino-3-[4-(cyclopropylsulfamoyl)phenyl]-5-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 316nMAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ289WPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM27488(2-amino-3-(4-{[3-(morpholin-4-yl)propyl]sulfamoyl}...)copy SMILEScopy InChI
Affinity DataIC50: 316nMAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ289WPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM27487(2-amino-3-(4-{[3-(dimethylamino)propyl]sulfamoyl}p...)copy SMILEScopy InChI
Affinity DataIC50: 316nMAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ289WPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50418177(CHEMBL1761504)copy SMILEScopy InChI
Affinity DataIC50: 316nMAssay Description:Inhibition of IKK-betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VS3PubMed
LigandPNGBDBM27467(2-amino-5-(4-chlorophenyl)-3-(4-sulfamoylphenyl)be...)copy SMILEScopy InChI
Affinity DataIC50: 398nMpH: 7.4 T: 2°CAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ289WPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM27478(2-amino-5-(4-methanesulfonylphenyl)-3-[4-(pyrrolid...)copy SMILEScopy InChI
Affinity DataIC50: 398nMAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ289WPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50418168(CHEMBL1761515)copy SMILEScopy InChI
Affinity DataIC50: 398nMAssay Description:Inhibition of IKK-betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VS3PubMed
LigandPNGBDBM27466(2-amino-5-(4-fluorophenyl)-3-(4-sulfamoylphenyl)be...)copy SMILEScopy InChI
Affinity DataIC50: 501nMpH: 7.4 T: 2°CAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ289WPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50418174(CHEMBL1761501)copy SMILEScopy InChI
Affinity DataIC50: 501nMAssay Description:Inhibition of IKK-betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VS3PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50418164(CHEMBL1761511 | D3RKN_31)copy SMILEScopy InChI
Affinity DataIC50: 501nMAssay Description:Inhibition of IKK-betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VS3PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50418182(CHEMBL1761509)copy SMILEScopy InChI
Affinity DataIC50: 501nMAssay Description:Inhibition of IKK-betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VS3PubMed
LigandPNGBDBM27489(2-amino-3-{4-[(2-aminoethyl)sulfamoyl]phenyl}-5-ph...)copy SMILEScopy InChI
Affinity DataIC50: 631nMAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ289WPubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
GSK

LigandPNGBDBM27445(5-(5,6-dimethoxy-1H-1,3-benzodiazol-1-yl)-3-[(4-me...)copy SMILEScopy InChI
Affinity DataIC50: 631nMpH: 7.2 T: 2°CAssay Description:The compound inhibitory activity was determined by incubation with purified PLK1 and biotinylated peptide substrate in the presence ATP/[gamma-33P]AT...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ311MPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM27465(2-amino-5-(4-fluorophenyl)-3-[4-(pyrrolidine-1-sul...)copy SMILEScopy InChI
Affinity DataIC50: 631nMAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ289WPubMed
LigandPNGBDBM27492(2-amino-5-phenyl-3-(4-{[2-(pyrrolidin-1-yl)ethyl]s...)copy SMILEScopy InChI
Affinity DataIC50: 794nMAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ289WPubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
GSK

LigandPNGBDBM27452(5-(5,6-dimethoxy-1H-1,3-benzodiazol-1-yl)-3-[(2-me...)copy SMILEScopy InChI
Affinity DataIC50: 794nMpH: 7.2 T: 2°CAssay Description:The compound inhibitory activity was determined by incubation with purified PLK1 and biotinylated peptide substrate in the presence ATP/[gamma-33P]AT...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ311MPubMed
LigandPNGBDBM27490(2-amino-3-{4-[(3-methoxypropyl)sulfamoyl]phenyl}-5...)copy SMILEScopy InChI
Affinity DataIC50: 794nMAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ289WPubMed
LigandPNGBDBM27447(5-(5,6-dimethoxy-1H-1,3-benzodiazol-1-yl)-3-(oxola...)copy SMILEScopy InChI
Affinity DataIC50: 794nMpH: 7.4 T: 2°CAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ311MPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50418176(CHEMBL1761503)copy SMILEScopy InChI
Affinity DataIC50: 794nMAssay Description:Inhibition of IKK-betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VS3PubMed
LigandPNGBDBM27491(2-amino-3-[4-(cyclopropylsulfamoyl)phenyl]-5-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ289WPubMed
LigandPNGBDBM27488(2-amino-3-(4-{[3-(morpholin-4-yl)propyl]sulfamoyl}...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ289WPubMed
LigandPNGBDBM27487(2-amino-3-(4-{[3-(dimethylamino)propyl]sulfamoyl}p...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ289WPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM27485(2-hydroxy-3-(4-methanesulfonamidophenyl)-5-phenylb...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ289WPubMed
LigandPNGBDBM27456(5-(1H-1,3-benzodiazol-1-yl)-3-(benzyloxy)thiophene...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMpH: 7.4 T: 2°CAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ311MPubMed
LigandPNGBDBM27471(2-amino-5-phenyl-3-(4-sulfamoylphenyl)benzamide | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMpH: 7.4 T: 2°CAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
TargetAurora kinase A(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50418165(CHEMBL1761512)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of Aurora A kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VS3PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50418163(CHEMBL1761510)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of BTKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VS3PubMed
Displayed 1 to 50 (of 167 total ) | Next | Last >>
Jump to: