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Found 345 with Last Name = 'scott' and Initial = 'jw'
TargetMelanocortin receptor 4(Mus musculus)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50144869(CHEMBL411775 | Tyr-c[Asp-His-DPhe-Arg-Trp-Asn-Ala-...)copy SMILEScopy InChI
Affinity DataIC50: 0.260nMAssay Description:Inhibitory concentration towards melanocortin MC4 receptor by displacing radioligand [125I]-hAGRP(82-132)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474BM0PubMed
TargetMelanocortin receptor 4(Mus musculus)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50144869(CHEMBL411775 | Tyr-c[Asp-His-DPhe-Arg-Trp-Asn-Ala-...)copy SMILEScopy InChI
Affinity DataIC50: 0.960nMAssay Description:Inhibitory concentration towards melanocortin MC4 receptor by displacing radioligand [125I]NDP-MSHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474BM0PubMed
TargetMelanocortin receptor 4(Mus musculus)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50144877(CHEMBL269274)copy SMILEScopy InChI
Affinity DataIC50: 1.46nMAssay Description:Inhibitory concentration towards melanocortin MC4 receptor by displacing radioligand [125I]NDP-MSHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474BM0PubMed
LigandPNGBDBM50572904(CHEMBL4857253)copy SMILES
Affinity DataIC50: 3nMAssay Description:Inhibition of NanoLuc-fused CAMKK2 (unknown origin) expressed in HEK293 cells after 24 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T9NPubMed
LigandPNGBDBM50296011(2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human CAMKK2 using CAMKKtide as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to controlMore data for this Ligand-Target Pair
LigandPNGBDBM50296011(2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of NanoLuc-fused CAMKK2 (unknown origin) expressed in HEK293 cells after 24 hrs by NanoBRET assayMore data for this Ligand-Target Pair
TargetMelanocortin receptor 4(Mus musculus)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)copy SMILEScopy InChI
Affinity DataIC50: 4.22nMAssay Description:Inhibitory concentration towards melanocortin MC4 receptor by displacing radioligand [125I]-NDP-MSH; ND = not determinedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474BM0PubMed
TargetMelanocortin receptor 4(Mus musculus)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50144877(CHEMBL269274)copy SMILEScopy InChI
Affinity DataIC50: 4.45nMAssay Description:Inhibitory concentration towards melanocortin MC4 receptor by displacing radioligand [125I]-hAGRP(82-132)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474BM0PubMed
TargetMelanocortin receptor 4(Mus musculus)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50144871(CHEMBL428134)copy SMILEScopy InChI
Affinity DataIC50: 4.74nMAssay Description:Inhibitory concentration towards melanocortin MC4 receptor by displacing radioligand [125I]-hAGRP(82-132)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474BM0PubMed
LigandPNGBDBM50572887(CHEMBL4875005)copy SMILES
Affinity DataIC50: 5nMAssay Description:Inhibition of human CAMKK2 using CAMKKtide as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T9NPubMed
TargetMelanocortin receptor 4(Mus musculus)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50144882(CHEMBL266288)copy SMILEScopy InChI
Affinity DataIC50: 5.48nMAssay Description:Inhibitory concentration towards melanocortin MC4 receptor by displacing radioligand [125I]-hAGRP(82-132)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474BM0PubMed
LigandPNGBDBM50572893(CHEMBL4870467)copy SMILES
Affinity DataIC50: 8.10nMAssay Description:Inhibition of NanoLuc-fused CAMKK2 (unknown origin) expressed in HEK293 cells after 24 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T9NPubMed
LigandPNGBDBM50572901(CHEMBL4849143)copy SMILES
Affinity DataIC50: 12nMAssay Description:Inhibition of human CAMKK2 using CAMKKtide as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T9NPubMed
LigandPNGBDBM50572900(CHEMBL4852523)copy SMILES
Affinity DataIC50: 13nMAssay Description:Inhibition of human CAMKK2 using CAMKKtide as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T9NPubMed
LigandPNGBDBM50572903(CHEMBL4876404)copy SMILES
Affinity DataIC50: 21nMAssay Description:Inhibition of human CAMKK2 using CAMKKtide as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T9NPubMed
LigandPNGBDBM50572890(CHEMBL4877552)copy SMILES
Affinity DataIC50: 21nMAssay Description:Inhibition of human CAMKK2 using CAMKKtide as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T9NPubMed
LigandPNGBDBM50572893(CHEMBL4870467)copy SMILES
Affinity DataIC50: 23nMAssay Description:Inhibition of human CAMKK2 using CAMKKtide as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T9NPubMed
LigandPNGBDBM50572896(CHEMBL4862562)copy SMILES
Affinity DataIC50: 24nMAssay Description:Inhibition of human CAMKK2 using CAMKKtide as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T9NPubMed
LigandPNGBDBM50271789(CHEMBL4125686)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of human CAMKK2 using CAMKKtide as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to controlMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T9NPubMed
LigandPNGBDBM50572893(CHEMBL4870467)copy SMILES
Affinity DataIC50: 27nMAssay Description:Inhibition of human CAMKK1 using CAMKKtide as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T9NPubMed
TargetMelanocortin receptor 4(Mus musculus)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50144871(CHEMBL428134)copy SMILEScopy InChI
Affinity DataIC50: 29.8nMAssay Description:Inhibitory concentration towards melanocortin MC4 receptor by displacing radioligand [125I]NDP-MSHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474BM0PubMed
LigandPNGBDBM50572898(CHEMBL4853274)copy SMILES
Affinity DataIC50: 31nMAssay Description:Inhibition of human CAMKK2 using CAMKKtide as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T9NPubMed
LigandPNGBDBM50572904(CHEMBL4857253)copy SMILES
Affinity DataIC50: 31nMAssay Description:Inhibition of human CAMKK1 using CAMKKtide as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T9NPubMed
LigandPNGBDBM50296011(2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of human CAMKK1 using CAMKKtide as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to controlMore data for this Ligand-Target Pair
LigandPNGBDBM50572904(CHEMBL4857253)copy SMILES
Affinity DataIC50: 39nMAssay Description:Inhibition of CAMKK2 in human LNCaP C4-2 cells assessed as reduction AMPK phosphorylation at Thr172 incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T9NPubMed
LigandPNGBDBM50572889(CHEMBL4851925)copy SMILES
Affinity DataIC50: 44nMAssay Description:Inhibition of human CAMKK2 using CAMKKtide as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T9NPubMed
LigandPNGBDBM50572904(CHEMBL4857253)copy SMILES
Affinity DataIC50: 51nMAssay Description:Inhibition of human CAMKK2 using CAMKKtide as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T9NPubMed
LigandPNGBDBM50572892(CHEMBL4873692)copy SMILES
Affinity DataIC50: 56nMAssay Description:Inhibition of human CAMKK2 using CAMKKtide as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T9NPubMed
LigandPNGBDBM50572886(CHEMBL4866741)copy SMILES
Affinity DataIC50: 65nMAssay Description:Inhibition of human CAMKK2 using CAMKKtide as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM50572902(CHEMBL4878827)copy SMILES
Affinity DataIC50: 96nMAssay Description:Inhibition of human CAMKK2 using CAMKKtide as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T9NPubMed
LigandPNGBDBM50572905(CHEMBL4857601)copy SMILES
Affinity DataIC50: 108nMAssay Description:Inhibition of human CAMKK2 using CAMKKtide as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T9NPubMed
LigandPNGBDBM50572891(CHEMBL4869147)copy SMILES
Affinity DataIC50: 120nMAssay Description:Inhibition of human CAMKK2 using CAMKKtide as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T9NPubMed
LigandPNGBDBM50572899(CHEMBL4877634)copy SMILES
Affinity DataIC50: 137nMAssay Description:Inhibition of human CAMKK2 using CAMKKtide as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T9NPubMed
LigandPNGBDBM50572900(CHEMBL4852523)copy SMILES
Affinity DataIC50: 140nMAssay Description:Inhibition of NanoLuc-fused CAMKK2 (unknown origin) expressed in HEK293 cells after 24 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T9NPubMed
LigandPNGBDBM50572888(CHEMBL4851892)copy SMILES
Affinity DataIC50: 145nMAssay Description:Inhibition of human CAMKK2 using CAMKKtide as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T9NPubMed
LigandPNGBDBM50572895(CHEMBL4854650)copy SMILES
Affinity DataIC50: 169nMAssay Description:Inhibition of human CAMKK2 using CAMKKtide as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T9NPubMed
LigandPNGBDBM50572896(CHEMBL4862562)copy SMILES
Affinity DataIC50: 170nMAssay Description:Inhibition of NanoLuc-fused CAMKK2 (unknown origin) expressed in HEK293 cells after 24 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T9NPubMed
LigandPNGBDBM50572890(CHEMBL4877552)copy SMILES
Affinity DataIC50: 190nMAssay Description:Inhibition of NanoLuc-fused CAMKK2 (unknown origin) expressed in HEK293 cells after 24 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T9NPubMed
LigandPNGBDBM50572894(CHEMBL4863974)copy SMILES
Affinity DataIC50: 193nMAssay Description:Inhibition of human CAMKK2 using CAMKKtide as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T9NPubMed
LigandPNGBDBM50271789(CHEMBL4125686)copy SMILEScopy InChI
Affinity DataIC50: 195nMAssay Description:Inhibition of human CAMKK1 using CAMKKtide as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to controlMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T9NPubMed
LigandPNGBDBM50572889(CHEMBL4851925)copy SMILES
Affinity DataIC50: 200nMAssay Description:Inhibition of NanoLuc-fused CAMKK2 (unknown origin) expressed in HEK293 cells after 24 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T9NPubMed
LigandPNGBDBM50572887(CHEMBL4875005)copy SMILES
Affinity DataIC50: 210nMAssay Description:Inhibition of NanoLuc-fused CAMKK2 (unknown origin) expressed in HEK293 cells after 24 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T9NPubMed
LigandPNGBDBM50572897(CHEMBL4857706)copy SMILES
Affinity DataIC50: 232nMAssay Description:Inhibition of human CAMKK2 using CAMKKtide as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T9NPubMed
LigandPNGBDBM50572890(CHEMBL4877552)copy SMILES
Affinity DataIC50: 238nMAssay Description:Inhibition of human CAMKK1 using CAMKKtide as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T9NPubMed
LigandPNGBDBM50572900(CHEMBL4852523)copy SMILES
Affinity DataIC50: 239nMAssay Description:Inhibition of human CAMKK1 using CAMKKtide as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T9NPubMed
LigandPNGBDBM50572891(CHEMBL4869147)copy SMILES
Affinity DataIC50: 240nMAssay Description:Inhibition of NanoLuc-fused CAMKK2 (unknown origin) expressed in HEK293 cells after 24 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T9NPubMed
TargetMelanocortin receptor 4(Mus musculus)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50144880(CHEMBL406032 | Tyr-c[Asp-His-Phe-Arg-Trp-Asn-Ala-P...)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Inhibitory concentration towards melanocortin MC4 receptor by displacing radioligand [125I]-hAGRP(82-132)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474BM0PubMed
LigandPNGBDBM50572903(CHEMBL4876404)copy SMILES
Affinity DataIC50: 290nMAssay Description:Inhibition of NanoLuc-fused CAMKK2 (unknown origin) expressed in HEK293 cells after 24 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T9NPubMed
LigandPNGBDBM50572887(CHEMBL4875005)copy SMILES
Affinity DataIC50: 384nMAssay Description:Inhibition of human CAMKK1 using CAMKKtide as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T9NPubMed
LigandPNGBDBM50572900(CHEMBL4852523)copy SMILES
Affinity DataIC50: 390nMAssay Description:Inhibition of CAMKK2 in human LNCaP C4-2 cells assessed as reduction AMPK phosphorylation at Thr172 incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T9NPubMed
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