Compile Data Set for Download or QSAR
Found 124 with Last Name = 'yates' and Initial = 'jwt'
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50468005(CHEMBL4288033)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of ATR in human HeLa cell nuclear extract using GST-fused p53N66 as substrate preincubated for 10 mins followed by ATP addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50468002(CHEMBL4291436)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of ATR in human HeLa cell nuclear extract using GST-fused p53N66 as substrate preincubated for 10 mins followed by ATP addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50468003(CHEMBL4281240)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of ATR in human HeLa cell nuclear extract using GST-fused p53N66 as substrate preincubated for 10 mins followed by ATP addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50468009(CHEMBL4286105)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of ATR in human HeLa cell nuclear extract using GST-fused p53N66 as substrate preincubated for 10 mins followed by ATP addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50468017(CHEMBL4291783)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of ATR in human HeLa cell nuclear extract using GST-fused p53N66 as substrate preincubated for 10 mins followed by ATP addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM60432(BDBM50468001 | US11236089, Compound AZD-6738 | US8...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of ATR in human HeLa cell nuclear extract using GST-fused p53N66 as substrate preincubated for 10 mins followed by ATP addition and measur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50468021(CHEMBL4278556)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of ATR in human HeLa cell nuclear extract using GST-fused p53N66 as substrate preincubated for 10 mins followed by ATP addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50427326(CHEMBL2325697)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of ATR in human HeLa cell nuclear extract using GST-fused p53N66 as substrate preincubated for 10 mins followed by ATP addition and measur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50468004(CHEMBL4286472)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of ATR in human HeLa cell nuclear extract using GST-fused p53N66 as substrate preincubated for 10 mins followed by ATP addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM103467(US8552004, 2.03)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of ATR in human HeLa cell nuclear extract using GST-fused p53N66 as substrate preincubated for 10 mins followed by ATP addition and measur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50427327(CHEMBL2325699)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of ATR in human HeLa cell nuclear extract using GST-fused p53N66 as substrate preincubated for 10 mins followed by ATP addition and measur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50468002(CHEMBL4291436)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of ATR in human HT29 cells after 60 mins by Hoechst 33258 staining-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50427321(CHEMBL2325704)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of ATR in human HeLa cell nuclear extract using GST-fused p53N66 as substrate preincubated for 10 mins followed by ATP addition and measur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50468006(CHEMBL4294006)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of ATR in human HeLa cell nuclear extract using GST-fused p53N66 as substrate preincubated for 10 mins followed by ATP addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM103467(US8552004, 2.03)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of ATR in human HT29 cells after 60 mins by Hoechst 33258 staining-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50468008(CHEMBL4280793)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of ATR in human HeLa cell nuclear extract using GST-fused p53N66 as substrate preincubated for 10 mins followed by ATP addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50468015(CHEMBL4284359)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of ATR in human HeLa cell nuclear extract using GST-fused p53N66 as substrate preincubated for 10 mins followed by ATP addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50468003(CHEMBL4281240)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of ATR in human HT29 cells after 60 mins by Hoechst 33258 staining-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM103471(BDBM50456371 | US8552004, 2.11)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of ATR in human HT29 cells after 60 mins by Hoechst 33258 staining-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50468013(CHEMBL4277395)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of ATR in human HeLa cell nuclear extract using GST-fused p53N66 as substrate preincubated for 10 mins followed by ATP addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50427297(CHEMBL2325439)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of ATR in human HeLa cell nuclear extract using GST-fused p53N66 as substrate preincubated for 10 mins followed by ATP addition and measur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50468005(CHEMBL4288033)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of ATR in human HT29 cells after 60 mins by Hoechst 33258 staining-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50468011(CHEMBL4294647)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of ATR in human HeLa cell nuclear extract using GST-fused p53N66 as substrate preincubated for 10 mins followed by ATP addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50468007(CHEMBL4284450)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of ATR in human HeLa cell nuclear extract using GST-fused p53N66 as substrate preincubated for 10 mins followed by ATP addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50468013(CHEMBL4277395)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of ATR in human HT29 cells after 60 mins by Hoechst 33258 staining-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50468018(CHEMBL4287961)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of ATR in human HeLa cell nuclear extract using GST-fused p53N66 as substrate preincubated for 10 mins followed by ATP addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50468020(CHEMBL4287852)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of ATR in human HeLa cell nuclear extract using GST-fused p53N66 as substrate preincubated for 10 mins followed by ATP addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50468024(CHEMBL4281973)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of ATR in human HT29 cells after 60 mins by Hoechst 33258 staining-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50468003(CHEMBL4281240)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50468009(CHEMBL4286105)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of ATR in human HT29 cells after 60 mins by Hoechst 33258 staining-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50468012(CHEMBL4281158)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of ATR in human HeLa cell nuclear extract using GST-fused p53N66 as substrate preincubated for 10 mins followed by ATP addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50427326(CHEMBL2325697)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50468017(CHEMBL4291783)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of ATR in human HT29 cells after 60 mins by Hoechst 33258 staining-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50468002(CHEMBL4291436)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50427326(CHEMBL2325697)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Inhibition of ATR in human HT29 cells after 60 mins by Hoechst 33258 staining-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM60432(BDBM50468001 | US11236089, Compound AZD-6738 | US8...)copy SMILEScopy InChI
Affinity DataIC50: 74nMAssay Description:Inhibition of ATR in human HT29 cells after 60 mins by Hoechst 33258 staining-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50468021(CHEMBL4278556)copy SMILEScopy InChI
Affinity DataIC50: 85nMAssay Description:Inhibition of ATR in human HT29 cells after 60 mins by Hoechst 33258 staining-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50468022(CHEMBL4284647)copy SMILEScopy InChI
Affinity DataIC50: 86nMAssay Description:Inhibition of ATR in human HT29 cells after 60 mins by Hoechst 33258 staining-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50468010(CHEMBL4277999)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of ATR in human HeLa cell nuclear extract using GST-fused p53N66 as substrate preincubated for 10 mins followed by ATP addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50468015(CHEMBL4284359)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of ATR in human HT29 cells after 60 mins by Hoechst 33258 staining-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50468004(CHEMBL4286472)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of ATR in human HT29 cells after 60 mins by Hoechst 33258 staining-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50427327(CHEMBL2325699)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of ATR in human HT29 cells after 60 mins by Hoechst 33258 staining-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50468006(CHEMBL4294006)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of ATR in human HT29 cells after 60 mins by Hoechst 33258 staining-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50468008(CHEMBL4280793)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of ATR in human HT29 cells after 60 mins by Hoechst 33258 staining-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50427297(CHEMBL2325439)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of ATR in human HT29 cells after 60 mins by Hoechst 33258 staining-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50427299(CHEMBL2325726)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of ATR in human HeLa cell nuclear extract using GST-fused p53N66 as substrate preincubated for 10 mins followed by ATP addition and measur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM103467(US8552004, 2.03)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50427308(CHEMBL2325717)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of ATR in human HeLa cell nuclear extract using GST-fused p53N66 as substrate preincubated for 10 mins followed by ATP addition and measur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50468011(CHEMBL4294647)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of ATR in human HT29 cells after 60 mins by Hoechst 33258 staining-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM60432(BDBM103466 | US8552004, 2.01)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of ATR in human HT29 cells after 60 mins by Hoechst 33258 staining-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
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