Compile Data Set for Download or QSAR
Found 38 with Last Name = 'kelly' and Initial = 'jx'
TargetChloroquine resistance transporter(Plasmodium falciparum)
Oregon Health & Science University

US Patent
LigandPNGBDBM434960(US10584098, Code ELQ-359)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:In vitro experiments show that the intrinsic antiplasmodial activity of ethylcarbonate ester ELQ-337 is indistinguishable from ELQ-300, with IC50 val...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213THUS Patent
TargetChloroquine resistance transporter(Plasmodium falciparum)
Oregon Health & Science University

US Patent
LigandPNGBDBM434954(US10584098, Code ELQ-336)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:In vitro experiments show that the intrinsic antiplasmodial activity of ethylcarbonate ester ELQ-337 is indistinguishable from ELQ-300, with IC50 val...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213THUS Patent
TargetChloroquine resistance transporter(Plasmodium falciparum)
Oregon Health & Science University

US Patent
LigandPNGBDBM434955(US10584098, Code ELQ-337)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:In vitro experiments show that the intrinsic antiplasmodial activity of ethylcarbonate ester ELQ-337 is indistinguishable from ELQ-300, with IC50 val...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213THUS Patent
TargetChloroquine resistance transporter(Plasmodium falciparum)
Oregon Health & Science University

US Patent
LigandPNGBDBM434964(US10584098, Code ELQ-379)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:In vitro experiments show that the intrinsic antiplasmodial activity of ethylcarbonate ester ELQ-337 is indistinguishable from ELQ-300, with IC50 val...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213THUS Patent
TargetChloroquine resistance transporter(Plasmodium falciparum)
Oregon Health & Science University

US Patent
LigandPNGBDBM434962(US10584098, Code ELQ-374)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:In vitro experiments show that the intrinsic antiplasmodial activity of ethylcarbonate ester ELQ-337 is indistinguishable from ELQ-300, with IC50 val...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213THUS Patent
TargetChloroquine resistance transporter(Plasmodium falciparum)
Oregon Health & Science University

US Patent
LigandPNGBDBM434956(US10584098, Code ELQ-354)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:In vitro experiments show that the intrinsic antiplasmodial activity of ethylcarbonate ester ELQ-337 is indistinguishable from ELQ-300, with IC50 val...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213THUS Patent
TargetChloroquine resistance transporter(Plasmodium falciparum)
Oregon Health & Science University

US Patent
LigandPNGBDBM434953(US10584098, Code ELQ-300)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:In vitro experiments show that the intrinsic antiplasmodial activity of ethylcarbonate ester ELQ-337 is indistinguishable from ELQ-300, with IC50 val...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213THUS Patent
TargetChloroquine resistance transporter(Plasmodium falciparum)
Oregon Health & Science University

US Patent
LigandPNGBDBM434961(US10584098, Code ELQ-373)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:In vitro experiments show that the intrinsic antiplasmodial activity of ethylcarbonate ester ELQ-337 is indistinguishable from ELQ-300, with IC50 val...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213THUS Patent
TargetChloroquine resistance transporter(Plasmodium falciparum)
Oregon Health & Science University

US Patent
LigandPNGBDBM434958(US10584098, Code ELQ-357)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:In vitro experiments show that the intrinsic antiplasmodial activity of ethylcarbonate ester ELQ-337 is indistinguishable from ELQ-300, with IC50 val...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213THUS Patent
TargetChloroquine resistance transporter(Plasmodium falciparum)
Oregon Health & Science University

US Patent
LigandPNGBDBM434957(US10584098, Code ELQ-355)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:In vitro experiments show that the intrinsic antiplasmodial activity of ethylcarbonate ester ELQ-337 is indistinguishable from ELQ-300, with IC50 val...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213THUS Patent
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM35229(3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-met...)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMedDrugBank
TargetChloroquine resistance transporter(Plasmodium falciparum)
Oregon Health & Science University

US Patent
LigandPNGBDBM434959(US10584098, Code ELQ-358)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:In vitro experiments show that the intrinsic antiplasmodial activity of ethylcarbonate ester ELQ-337 is indistinguishable from ELQ-300, with IC50 val...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213THUS Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50010859(CHEMBL11 | IMIPRAMINE HYDROCHLORIDE | IMIPRAMINE P...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of [3H]5HT uptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetChloroquine resistance transporter(Plasmodium falciparum)
Oregon Health & Science University

US Patent
LigandPNGBDBM434963(US10584098, Code ELQ-375)copy SMILEScopy InChI
Affinity DataIC50: 8.20nMAssay Description:In vitro experiments show that the intrinsic antiplasmodial activity of ethylcarbonate ester ELQ-337 is indistinguishable from ELQ-300, with IC50 val...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213THUS Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM35229(3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-met...)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Inhibition of [3H]5HT uptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMedDrugBank
TargetHistamine H1 receptor(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM35938(1-(p-chlorophenyl)-1-(2-pyridyl)-3-N,N-dimethylpro...)copy SMILEScopy InChI
Affinity DataIC50: 66nMAssay Description:Displacement of [3H]pyrilamine from human histamine receptor subtype 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMedDrugBank
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50010859(CHEMBL11 | IMIPRAMINE HYDROCHLORIDE | IMIPRAMINE P...)copy SMILEScopy InChI
Affinity DataIC50: 74nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMedDrugBank
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of [3H]5HT uptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249783(10-(6-(diethylamino)hexyl)acridin-9(10H)-one | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of [3H]5HT uptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249783(10-(6-(diethylamino)hexyl)acridin-9(10H)-one | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Displacement of [3H]pyrilamine from human histamine receptor subtype 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249782(10-(5-(diethylamino)pentyl)acridin-9(10H)-one | CH...)copy SMILEScopy InChI
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of [3H]5HT uptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249782(10-(5-(diethylamino)pentyl)acridin-9(10H)-one | CH...)copy SMILEScopy InChI
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249783(10-(6-(diethylamino)hexyl)acridin-9(10H)-one | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249781(10-(4-(diethylamino)butyl)acridin-9(10H)-one | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249780(10-(3-(diethylamino)propyl)acridin-9(10H)-one | CH...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249759(10-(2-(diethylamino)ethyl)acridin-9(10H)-one | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249781(10-(4-(diethylamino)butyl)acridin-9(10H)-one | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]5HT uptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249780(10-(3-(diethylamino)propyl)acridin-9(10H)-one | CH...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]5HT uptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249759(10-(2-(diethylamino)ethyl)acridin-9(10H)-one | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]5HT uptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249783(10-(6-(diethylamino)hexyl)acridin-9(10H)-one | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249782(10-(5-(diethylamino)pentyl)acridin-9(10H)-one | CH...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249781(10-(4-(diethylamino)butyl)acridin-9(10H)-one | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249759(10-(2-(diethylamino)ethyl)acridin-9(10H)-one | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249780(10-(3-(diethylamino)propyl)acridin-9(10H)-one | CH...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50010859(CHEMBL11 | IMIPRAMINE HYDROCHLORIDE | IMIPRAMINE P...)copy SMILEScopy InChI
Affinity DataIC50: 2.56E+4nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMedDrugBank
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM35229(3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-met...)copy SMILEScopy InChI
Affinity DataIC50: 8.20E+4nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed