Compile Data Set for Download or QSAR
Found 81 with Last Name = 'browning' and Initial = 'k'
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50153990(4-[2-(4-Ethoxy-phenyl)-pyrazolo[1,5-b]pyridazin-3-...)copy SMILEScopy InChI
Affinity DataIC50: 0.440nMAssay Description:Inhibition of human cyclooxygenase-2 expressed in COS cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4HZ7PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50029600(5-Bromo-2-(4-fluoro-phenyl)-3-(4-methanesulfonyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human COX2 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66KSCPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50153994(3-(4-Methanesulfonyl-phenyl)-2-phenyl-pyrazolo[1,5...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human cyclooxygenase-2 expressed in COS cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4HZ7PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50153982(2-(4-Ethoxy-phenyl)-3-(4-methanesulfonyl-phenyl)-p...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human cyclooxygenase-2 expressed in COS cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4HZ7PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50153989(3-(4-Methanesulfonyl-phenyl)-2-(4-methoxy-phenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human cyclooxygenase-2 expressed in COS cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4HZ7PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50153987(4-[2-(4-Fluoro-phenyl)-pyrazolo[1,5-b]pyridazin-3-...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human cyclooxygenase-2 expressed in COS cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4HZ7PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50297695(2-(cyclohexylmethyl)-4-(4-fluorophenyl)-5-(4-(meth...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of human COX2 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66KSCPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50153981(4-[2-(4-Ethoxy-phenyl)-6-methylsulfanyl-pyrazolo[1...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human cyclooxygenase-2 expressed in COS cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4HZ7PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50153997(3-(4-Methanesulfonyl-phenyl)-2-p-tolyl-pyrazolo[1,...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of human cyclooxygenase-2 expressed in COS cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4HZ7PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50297696(4-(4-fluorophenyl)-2-((1-methyl-1H-pyrrol-2-yl)met...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of human COX2 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66KSCPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50153991(2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-6...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of human cyclooxygenase-2 expressed in COS cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4HZ7PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50153992(4-[2-(4-Fluoro-phenyl)-6-methoxy-pyrazolo[1,5-b]py...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of human cyclooxygenase-2 expressed in COS cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4HZ7PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50153980(3-(4-Methanesulfonyl-phenyl)-6-methyl-2-phenyl-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of human cyclooxygenase-2 expressed in COS cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4HZ7PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM22369(4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofu...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of human cyclooxygenase-2 expressed in COS cellsMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50153998(2-(3-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-p...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of human cyclooxygenase-2 expressed in COS cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4HZ7PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50153985(2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-p...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of human cyclooxygenase-2 expressed in COS cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4HZ7PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50297709(2-((4-(4-fluorophenyl)-5-(4-(methylsulfonyl)phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of human COX2 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66KSCPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50153984(6-Ethoxy-2-(4-fluoro-phenyl)-3-(4-methanesulfonyl-...)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of human cyclooxygenase-2 expressed in COS cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4HZ7PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50153996(6-Ethyl-2-(4-fluoro-phenyl)-3-(4-methanesulfonyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibition of human cyclooxygenase-2 expressed in COS cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4HZ7PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50153999(3-(4-Methanesulfonyl-phenyl)-6-methoxy-2-p-tolyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of human cyclooxygenase-2 expressed in COS cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4HZ7PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50153988(2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-6...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of human cyclooxygenase-2 expressed in COS cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4HZ7PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50297697(4-(4-fluorophenyl)-5-(4-(methylsulfonyl)phenyl)-N-...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of human COX2 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66KSCPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50153983(2-(4-Fluoro-phenyl)-6-isopropoxy-3-(4-methanesulfo...)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of human cyclooxygenase-2 expressed in COS cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4HZ7PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50297708((4-(4-fluorophenyl)-5-(4-(methylsulfonyl)phenyl)py...)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of human COX2 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66KSCPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50029616(5-(4-Fluoro-phenyl)-1-(4-methanesulfonyl-phenyl)-3...)copy SMILEScopy InChI
Affinity DataIC50: 66nMAssay Description:Inhibition of human COX2 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66KSCPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Inhibition of human cyclooxygenase-2 expressed in COS cellsMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50297698(4-(4-fluorophenyl)-N-methyl-5-(4-(methylsulfonyl)p...)copy SMILEScopy InChI
Affinity DataIC50: 85nMAssay Description:Inhibition of human COX2 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66KSCPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50297699(2-benzyl-4-(4-fluorophenyl)-5-(4-(methylsulfonyl)p...)copy SMILEScopy InChI
Affinity DataIC50: 104nMAssay Description:Inhibition of human COX2 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66KSCPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50297700(2-(2,4-difluorobenzyl)-4-(4-fluorophenyl)-5-(4-(me...)copy SMILEScopy InChI
Affinity DataIC50: 114nMAssay Description:Inhibition of human COX2 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66KSCPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM13063(4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzene-1-sul...)copy SMILEScopy InChI
Affinity DataIC50: 183nMAssay Description:Inhibition of human cyclooxygenase-2 expressed in COS cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4HZ7PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50153995(4-[2-(4-Ethoxy-phenyl)-6-methanesulfonyl-pyrazolo[...)copy SMILEScopy InChI
Affinity DataIC50: 264nMAssay Description:Inhibition of human cyclooxygenase-2 expressed in COS cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4HZ7PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50297701(2-(4-fluorobenzyl)-4-(4-fluorophenyl)-5-(4-(methyl...)copy SMILEScopy InChI
Affinity DataIC50: 277nMAssay Description:Inhibition of human COX2 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66KSCPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50072064(5-Chloro-3-(4-methanesulfonyl-phenyl)-6''-methyl-[...)copy SMILEScopy InChI
Affinity DataIC50: 347nMAssay Description:Inhibition of human cyclooxygenase-2 expressed in COS cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4HZ7PubMedDrugBank
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50153986(2-(4-Fluoro-phenyl)-6-methanesulfonyl-3-(4-methane...)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Inhibition of human cyclooxygenase-2 expressed in COS cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4HZ7PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50153993(4-[2-(4-Trifluoromethoxy-phenyl)-pyrazolo[1,5-b]py...)copy SMILEScopy InChI
Affinity DataIC50: 388nMAssay Description:Inhibition of human cyclooxygenase-2 expressed in COS cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4HZ7PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50297702(CHEMBL562768 | N-benzyl-4-(4-fluorophenyl)-5-(4-(m...)copy SMILEScopy InChI
Affinity DataIC50: 686nMAssay Description:Inhibition of human COX2 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66KSCPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50297710(2-Benzyl-4-(4-fluoro-phenyl)-5-(4-methanesulfonyl-...)copy SMILEScopy InChI
Affinity DataIC50: 717nMAssay Description:Inhibition of human COX2 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66KSCPubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50029600(5-Bromo-2-(4-fluoro-phenyl)-3-(4-methanesulfonyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 870nMAssay Description:Inhibition of human COX1 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66KSCPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50297703(4-(4-fluorophenyl)-2-isopropyl-5-(4-(methylsulfony...)copy SMILEScopy InChI
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of human COX2 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66KSCPubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 1.69E+3nMAssay Description:Inhibition of human cyclooxygenase-1 expressed in COS cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4HZ7PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50153992(4-[2-(4-Fluoro-phenyl)-6-methoxy-pyrazolo[1,5-b]py...)copy SMILEScopy InChI
Affinity DataIC50: 2.61E+3nMAssay Description:Inhibition of human cyclooxygenase-1 expressed in COS cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4HZ7PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50297695(2-(cyclohexylmethyl)-4-(4-fluorophenyl)-5-(4-(meth...)copy SMILEScopy InChI
Affinity DataIC50: 2.97E+3nMAssay Description:Inhibition of human COX1 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66KSCPubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50153990(4-[2-(4-Ethoxy-phenyl)-pyrazolo[1,5-b]pyridazin-3-...)copy SMILEScopy InChI
Affinity DataIC50: 3.83E+3nMAssay Description:Inhibition of human cyclooxygenase-1 expressed in COS cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4HZ7PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50153989(3-(4-Methanesulfonyl-phenyl)-2-(4-methoxy-phenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 3.88E+3nMAssay Description:Inhibition of human cyclooxygenase-1 expressed in COS cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4HZ7PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50297698(4-(4-fluorophenyl)-N-methyl-5-(4-(methylsulfonyl)p...)copy SMILEScopy InChI
Affinity DataIC50: 4.34E+3nMAssay Description:Inhibition of human COX1 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66KSCPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50297706(4-(4-fluorophenyl)-5-(4-(methylsulfonyl)phenyl)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 4.64E+3nMAssay Description:Inhibition of human COX2 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66KSCPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50297704(4-(4-fluorophenyl)-5-(4-(methylsulfonyl)phenyl)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 5.26E+3nMAssay Description:Inhibition of human COX2 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66KSCPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50297705(4-(4-fluorophenyl)-5-(4-(methylsulfonyl)phenyl)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 6.32E+3nMAssay Description:Inhibition of human COX2 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66KSCPubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50297696(4-(4-fluorophenyl)-2-((1-methyl-1H-pyrrol-2-yl)met...)copy SMILEScopy InChI
Affinity DataIC50: 6.54E+3nMAssay Description:Inhibition of human COX1 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66KSCPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50297707(4-(4-fluorophenyl)-5-(4-(methylsulfonyl)phenyl)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of human COX2 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66KSCPubMed
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