Compile Data Set for Download or QSAR
Found 276 with Last Name = 'connolly' and Initial = 'k'
TargetCaspase-1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM12066((3S)-3-({2-[4-(butan-2-yl)-3-methylphenoxy]benzene...)copy SMILEScopy InChI
Affinity DataKi:  100nM ΔG°:  -41.6kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9896PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM12064((3S)-3-({2-[3-methyl-4-(propan-2-yl)phenoxy]benzen...)copy SMILEScopy InChI
Affinity DataKi:  110nM ΔG°:  -41.3kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9896PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM12070((3S)-4-oxo-3-{[2-(4-phenylphenoxy)benzene]sulfonam...)copy SMILEScopy InChI
Affinity DataKi:  290nM ΔG°:  -38.8kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9896PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM12062((3S)-4-oxo-3-({2-[3-(propan-2-yl)phenoxy]benzene}s...)copy SMILEScopy InChI
Affinity DataKi:  410nM ΔG°:  -37.9kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9896PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM12058((3S)-3-{[2-(3-methylphenoxy)benzene]sulfonamido}-4...)copy SMILEScopy InChI
Affinity DataKi:  430nM ΔG°:  -37.8kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9896PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM12067((3S)-4-oxo-3-({2-[4-(pentan-3-yl)phenoxy]benzene}s...)copy SMILEScopy InChI
Affinity DataKi:  440nM ΔG°:  -37.7kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9896PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM12061((3S)-4-oxo-3-{[2-(3,4,5-trimethylphenoxy)benzene]s...)copy SMILEScopy InChI
Affinity DataKi:  450nM ΔG°:  -37.7kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9896PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM12065((3S)-3-({2-[4-(butan-2-yl)phenoxy]benzene}sulfonam...)copy SMILEScopy InChI
Affinity DataKi:  490nM ΔG°:  -37.5kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9896PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM12063((3S)-4-oxo-3-({2-[4-(propan-2-yl)phenoxy]benzene}s...)copy SMILEScopy InChI
Affinity DataKi:  620nM ΔG°:  -36.9kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9896PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM12068((3S)-3-{[2-(4-cyclopentylphenoxy)benzene]sulfonami...)copy SMILEScopy InChI
Affinity DataKi:  880nM ΔG°:  -36.0kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9896PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM12069((3S)-3-{[2-(4-cyclohexylphenoxy)benzene]sulfonamid...)copy SMILEScopy InChI
Affinity DataKi:  900nM ΔG°:  -35.9kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9896PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM12060((3S)-3-{[2-(2,3-dimethylphenoxy)benzene]sulfonamid...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nM ΔG°:  -35.6kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9896PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM12059((3S)-3-{[2-(4-methylphenoxy)benzene]sulfonamido}-4...)copy SMILEScopy InChI
Affinity DataKi:  1.10E+3nM ΔG°:  -35.4kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9896PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM12055((3S)-4-oxo-3-[(2-phenylbenzene)sulfonamido]butanoi...)copy SMILEScopy InChI
Affinity DataKi:  1.60E+3nM ΔG°:  -34.4kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9896PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM12056((3S)-4-oxo-3-[(2-phenoxybenzene)sulfonamido]butano...)copy SMILEScopy InChI
Affinity DataKi:  2.40E+3nM ΔG°:  -33.4kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9896PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM12057((3S)-3-{[2-(2-methylphenoxy)benzene]sulfonamido}-4...)copy SMILEScopy InChI
Affinity DataKi:  3.00E+3nM ΔG°:  -32.8kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9896PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM12071(4-[4-(2-{[(2S)-1-carboxy-3-oxopropan-2-yl]sulfamoy...)copy SMILEScopy InChI
Affinity DataKi:  4.20E+3nM ΔG°:  -31.9kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9896PubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Glaxo Wellcome Research

Curated by ChEMBL
LigandPNGBDBM50048241((3S,4S)-3-Acetyl-4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataKi:  7.90E+3nMAssay Description:Inhibition of human Phosphodiesterase 7More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24748ZNPubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Bos taurus)
Glaxo Wellcome Research

Curated by ChEMBL
LigandPNGBDBM50048241((3S,4S)-3-Acetyl-4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of bovine Phosphodiesterase 2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24748ZNPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Glaxo Wellcome Research

Curated by ChEMBL
LigandPNGBDBM50048241((3S,4S)-3-Acetyl-4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of Phosphodiesterase 5 isolated from human tracheaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24748ZNPubMed
TargetSUMO-activating enzyme subunit 1/2(Homo sapiens (Human))TBA
LigandPNGBDBM50575601(CHEMBL4858933)copy SMILES
Affinity DataIC50: 0.100nMAssay Description:Inhibition of recombinant SAE (unknown origin) assessed as reduction in transfer of SUMO1 to UBC9 using SUMO1 as a substrate in presence of ATP at Km...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0KZ8PubMed
TargetSUMO-activating enzyme subunit 1/2(Homo sapiens (Human))TBA
LigandPNGBDBM50575593(CHEMBL4878832)copy SMILES
Affinity DataIC50: 0.100nMAssay Description:Inhibition of recombinant SAE (unknown origin) assessed as reduction in transfer of SUMO1 to UBC9 using SUMO1 as a substrate in presence of ATP at Km...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0KZ8PubMed
TargetSUMO-activating enzyme subunit 1/2(Homo sapiens (Human))TBA
LigandPNGBDBM50575590(CHEMBL4864361)copy SMILES
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant SAE (unknown origin) assessed as reduction in transfer of SUMO1 to UBC9 using SUMO1 as a substrate in presence of ATP at Km...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0KZ8PubMed
TargetSUMO-activating enzyme subunit 1/2(Homo sapiens (Human))TBA
LigandPNGBDBM50575588(CHEMBL4854038)copy SMILES
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant SAE (unknown origin) assessed as reduction in transfer of SUMO1 to UBC9 using SUMO1 as a substrate in presence of ATP at Km...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0KZ8PubMed
TargetSUMO-activating enzyme subunit 1/2(Homo sapiens (Human))TBA
LigandPNGBDBM50575591(CHEMBL4850183)copy SMILES
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant SAE (unknown origin) assessed as reduction in transfer of SUMO1 to UBC9 using SUMO1 as a substrate in presence of ATP at Km...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0KZ8PubMed
TargetSUMO-activating enzyme subunit 1/2(Homo sapiens (Human))TBA
LigandPNGBDBM50575600(CHEMBL4873487)copy SMILES
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant SAE (unknown origin) assessed as reduction in transfer of SUMO1 to UBC9 using SUMO1 as a substrate in presence of ATP at Km...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0KZ8PubMed
TargetSUMO-activating enzyme subunit 1/2(Homo sapiens (Human))TBA
LigandPNGBDBM50575587(CHEMBL4852516)copy SMILES
Affinity DataIC50: 0.300nMAssay Description:Inhibition of recombinant SAE (unknown origin) assessed as reduction in transfer of SUMO1 to UBC9 using SUMO1 as a substrate in presence of ATP at Km...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0KZ8PubMed
TargetSUMO-activating enzyme subunit 1/2(Homo sapiens (Human))TBA
LigandPNGBDBM50575599(CHEMBL4848140)copy SMILES
Affinity DataIC50: 0.300nMAssay Description:Inhibition of recombinant SAE (unknown origin) assessed as reduction in transfer of SUMO1 to UBC9 using SUMO1 as a substrate in presence of ATP at Km...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0KZ8PubMed
TargetSUMO-activating enzyme subunit 1/2(Homo sapiens (Human))TBA
LigandPNGBDBM50575592(CHEMBL4860917)copy SMILES
Affinity DataIC50: 0.300nMAssay Description:Inhibition of recombinant SAE (unknown origin) assessed as reduction in transfer of SUMO1 to UBC9 using SUMO1 as a substrate in presence of ATP at Km...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0KZ8PubMed
TargetSUMO-activating enzyme subunit 1/2(Homo sapiens (Human))TBA
LigandPNGBDBM50575586(CHEMBL4848442)copy SMILES
Affinity DataIC50: 0.300nMAssay Description:Inhibition of recombinant SAE (unknown origin) assessed as reduction in transfer of SUMO1 to UBC9 using SUMO1 as a substrate in presence of ATP at Km...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0KZ8PubMed
TargetSUMO-activating enzyme subunit 1/2(Homo sapiens (Human))TBA
LigandPNGBDBM50575589(CHEMBL4877684)copy SMILES
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant SAE (unknown origin) assessed as reduction in transfer of SUMO1 to UBC9 using SUMO1 as a substrate in presence of ATP at Km...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0KZ8PubMed
TargetSUMO-activating enzyme subunit 1/2(Homo sapiens (Human))TBA
LigandPNGBDBM50575568(CHEMBL4870385)copy SMILES
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant SAE (unknown origin) assessed as reduction in transfer of SUMO1 to UBC9 using SUMO1 as a substrate in presence of ATP at Km...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0KZ8PubMed
TargetSUMO-activating enzyme subunit 1/2(Homo sapiens (Human))TBA
LigandPNGBDBM50575604(CHEMBL4873956)copy SMILES
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant SAE (unknown origin) assessed as reduction in transfer of SUMO1 to UBC9 using SUMO1 as a substrate in presence of ATP at Km...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0KZ8PubMed
TargetSUMO-activating enzyme subunit 1/2(Homo sapiens (Human))TBA
LigandPNGBDBM50575596(CHEMBL4848114)copy SMILES
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant SAE (unknown origin) assessed as reduction in transfer of SUMO1 to UBC9 using SUMO1 as a substrate in presence of ATP at Km...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetSUMO-activating enzyme subunit 1/2(Homo sapiens (Human))TBA
LigandPNGBDBM50575594(CHEMBL4856793)copy SMILES
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant SAE (unknown origin) assessed as reduction in transfer of SUMO1 to UBC9 using SUMO1 as a substrate in presence of ATP at Km...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0KZ8PubMed
TargetSUMO-activating enzyme subunit 1/2(Homo sapiens (Human))TBA
LigandPNGBDBM50575594(CHEMBL4856793)copy SMILES
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant SAE (unknown origin) assessed as reduction in transfer of SUMO1 to UBC9 using SUMO1 as a substrate in presence of ATP at Km...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0KZ8PubMed
TargetSUMO-activating enzyme subunit 1/2(Homo sapiens (Human))TBA
LigandPNGBDBM50575597(CHEMBL4861509)copy SMILES
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant SAE (unknown origin) assessed as reduction in transfer of SUMO1 to UBC9 using SUMO1 as a substrate in presence of ATP at Km...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0KZ8PubMed
TargetSUMO-activating enzyme subunit 1/2(Homo sapiens (Human))TBA
LigandPNGBDBM50575579(CHEMBL4847817)copy SMILES
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant SAE (unknown origin) assessed as reduction in transfer of SUMO1 to UBC9 using SUMO1 as a substrate in presence of ATP at Km...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0KZ8PubMed
TargetSUMO-activating enzyme subunit 1/2(Homo sapiens (Human))TBA
LigandPNGBDBM50575565(CHEMBL4864280)copy SMILES
Affinity DataIC50: 0.700nMAssay Description:Inhibition of recombinant SAE (unknown origin) assessed as reduction in transfer of SUMO1 to UBC9 using SUMO1 as a substrate in presence of ATP at Km...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0KZ8PubMed
TargetSUMO-activating enzyme subunit 1/2(Homo sapiens (Human))TBA
LigandPNGBDBM50575576(CHEMBL4874906)copy SMILES
Affinity DataIC50: 0.700nMAssay Description:Inhibition of recombinant SAE (unknown origin) assessed as reduction in transfer of SUMO1 to UBC9 using SUMO1 as a substrate in presence of ATP at Km...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0KZ8PubMed
TargetSUMO-activating enzyme subunit 1/2(Homo sapiens (Human))TBA
LigandPNGBDBM50575606(CHEMBL4856040)copy SMILES
Affinity DataIC50: 0.800nMAssay Description:Inhibition of recombinant SAE (unknown origin) assessed as reduction in transfer of SUMO1 to UBC9 using SUMO1 as a substrate in presence of ATP at Km...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0KZ8PubMed
TargetSUMO-activating enzyme subunit 1/2(Homo sapiens (Human))TBA
LigandPNGBDBM50575595(CHEMBL4849766)copy SMILES
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant SAE (unknown origin) assessed as reduction in transfer of SUMO1 to UBC9 using SUMO1 as a substrate in presence of ATP at Km...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0KZ8PubMed
TargetSUMO-activating enzyme subunit 1/2(Homo sapiens (Human))TBA
LigandPNGBDBM50575581(CHEMBL4860263)copy SMILES
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant SAE (unknown origin) assessed as reduction in transfer of SUMO1 to UBC9 using SUMO1 as a substrate in presence of ATP at Km...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0KZ8PubMed
TargetSUMO-activating enzyme subunit 1/2(Homo sapiens (Human))TBA
LigandPNGBDBM50575581(CHEMBL4860263)copy SMILES
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant SAE (unknown origin) assessed as reduction in transfer of SUMO1 to UBC9 using SUMO1 as a substrate in presence of ATP at Km...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0KZ8PubMed
TargetSUMO-activating enzyme subunit 1/2(Homo sapiens (Human))TBA
LigandPNGBDBM462705(US10780090, Compound I-43 | {(1R,2S,4R)-4-[(5-{[4-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant SAE (unknown origin) assessed as reduction in transfer of SUMO1 to UBC9 using SUMO1 as a substrate in presence of ATP at Km...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0KZ8PubMed
TargetSUMO-activating enzyme subunit 1/2(Homo sapiens (Human))TBA
LigandPNGBDBM50575605(CHEMBL4865157)copy SMILES
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant SAE (unknown origin) assessed as reduction in transfer of SUMO1 to UBC9 using SUMO1 as a substrate in presence of ATP at Km...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0KZ8PubMed
TargetSUMO-activating enzyme subunit 1/2(Homo sapiens (Human))TBA
LigandPNGBDBM462958(US10780090, Compound I-263a | US10780090, Compound...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant SAE (unknown origin) assessed as reduction in transfer of SUMO1 to UBC9 using SUMO1 as a substrate in presence of ATP at Km...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0KZ8PubMed
TargetSUMO-activating enzyme subunit 1/2(Homo sapiens (Human))TBA
LigandPNGBDBM50575575(CHEMBL4870143)copy SMILES
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant SAE (unknown origin) assessed as reduction in transfer of SUMO1 to UBC9 using SUMO1 as a substrate in presence of ATP at Km...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0KZ8PubMed
TargetSUMO-activating enzyme subunit 1/2(Homo sapiens (Human))TBA
LigandPNGBDBM50575555(CHEMBL4878088)copy SMILES
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant SAE (unknown origin) assessed as reduction in transfer of SUMO1 to UBC9 using SUMO1 as a substrate in presence of ATP at Km...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetSUMO-activating enzyme subunit 1/2(Homo sapiens (Human))TBA
LigandPNGBDBM50575570(CHEMBL4865787)copy SMILES
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant SAE (unknown origin) assessed as reduction in transfer of SUMO1 to UBC9 using SUMO1 as a substrate in presence of ATP at Km...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0KZ8PubMed
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