Compile Data Set for Download or QSAR
Found 257 with Last Name = 'daly' and Initial = 'k'
TargetSmoothened homolog(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50539187(CHEMBL4632769)copy SMILEScopy InChI
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of SMO-mediated hedgehog signalling pathway in human HPEM cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9TNCPubMed
TargetSmoothened homolog(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50539188(CHEMBL4637222)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of SMO-mediated hedgehog signalling pathway in human HPEM cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9TNCPubMed
TargetSmoothened homolog(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50249522(2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(me...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of SMO-mediated hedgehog signalling pathway in human HPEM cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of full length human PARP1 expressed in Baculovirus infected Sf9 insect cells using activated DNA as substrate after 1 hr by streptavidin-...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50499821(CHEMBL3740104)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human PARP2 (2 to 583 residues) expressed in Baculovirus infected Sf9 insect cells using activated DNA as substrate after 1 hr by strep...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2T0JPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50499821(CHEMBL3740104)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of full length human PARP1 expressed in Baculovirus infected Sf9 insect cells using activated DNA as substrate after 1 hr by streptavidin-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2T0JPubMed
TargetSmoothened homolog(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50388722(CHEMBL2059865)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibition of SMO-mediated hedgehog signalling pathway in human HPEM cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9TNCPubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human PARP2 (2 to 583 residues) expressed in Baculovirus infected Sf9 insect cells using activated DNA as substrate after 1 hr by strep...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243624((R)-1-(3-(azepan-3-ylcarbamoyl)-5-phenylthiophen-2...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102Z9PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243148(1-(3-((S)-piperidin-3-ylcarbamoyl)-5-(thiophen-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102Z9PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243151((S)-1-(3-(piperidin-3-ylcarbamoyl)-5-(pyridin-4-yl...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102Z9PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243047(1-(3-((S)-piperidin-3-ylcarbamoyl)-5-(3-carbamoylp...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102Z9PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243201((S)-1-(5-(4-carbamoylphenyl)-3-(piperidin-3-ylcarb...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102Z9PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243049((S)-1-(5-(4-cyanophenyl)-3-(piperidin-3-ylcarbamoy...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102Z9PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243102((S)-1-(5-(4-(methylsulfonyl)phenyl)-3-(piperidin-3...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102Z9PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243150(1-(3-((S)-piperidin-3-ylcarbamoyl)-5-(pyridin-3-yl...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102Z9PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243149(1-(3-((S)-piperidin-3-ylcarbamoyl)-5-(thiophen-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102Z9PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243147((S)-1-(5-(4-acetylphenyl)-3-(piperidin-3-ylcarbamo...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102Z9PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50242821((S)-1-(5-(4-hydroxyphenyl)-3-(piperidin-3-ylcarbam...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102Z9PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243258((S)-1-(5-phenyl-3-(piperidin-3-ylcarbamoyl)thiophe...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243100(1-(3-((S)-piperidin-3-ylcarbamoyl)-5-(3-acetamidop...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102Z9PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50499821(CHEMBL3740104)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human TNKS1 (1001 to 1327 residues) expressed in Baculovirus infected Sf9 insect cells using activated DNA as substrate after 1 hr by s...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50242824((S)-1-(5-(4-fluorophenyl)-3-(piperidin-3-ylcarbamo...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102Z9PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243203((S)-1-(5-(4-(dimethylcarbamoyl)phenyl)-3-(piperidi...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102Z9PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243202((S)-1-(5-(4-(methylcarbamoyl)phenyl)-3-(piperidin-...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102Z9PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50242822(1-(3-((S)-piperidin-3-ylcarbamoyl)-5-(2-fluorophen...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102Z9PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243046((S)-1-(5-(4-chlorophenyl)-3-(piperidin-3-ylcarbamo...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243048((S)-1-(3-(piperidin-3-ylcarbamoyl)-5-p-tolylthioph...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102Z9PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243204((S)-1-(5-(4-(morpholine-4-carbonyl)phenyl)-3-(pipe...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102Z9PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243531(1-(5-(4-(2-(diethylamino)ethoxy)phenyl)-3-(piperid...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102Z9PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243666((+/-)-1-(5-(3-(2-(diethylamino)ethoxy)phenyl)-3-(p...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102Z9PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50242820(1-(3-((S)-piperidin-3-ylcarbamoyl)-5-(3-(2-(diethy...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102Z9PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50242823(1-(3-((S)-piperidin-3-ylcarbamoyl)-5-(3-fluorophen...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102Z9PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243261((S)-1-(3-(piperidin-3-ylcarbamoyl)-5-(4-(piperidin...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102Z9PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243098((S)-1-(5-(4-aminophenyl)-3-(piperidin-3-ylcarbamoy...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102Z9PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50242893(1-(3-((S)-piperidin-3-ylcarbamoyl)-5-(3-chlorophen...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102Z9PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243471(1-(3-carbamoyl-5-(4-((2,2,6,6-tetramethylpiperidin...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102Z9PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243050((S)-1-(3-(piperidin-3-ylcarbamoyl)-5-(4-(trifluoro...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102Z9PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243424(1-(5-(4-((4-methoxybenzylamino)methyl)phenyl)-3-ca...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102Z9PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50499822(CHEMBL3740897)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of full length human PARP1 expressed in Baculovirus infected Sf9 insect cells using activated DNA as substrate after 1 hr by streptavidin-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2T0JPubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50499822(CHEMBL3740897)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human PARP2 (2 to 583 residues) expressed in Baculovirus infected Sf9 insect cells using activated DNA as substrate after 1 hr by strep...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2T0JPubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243584(1-(3-((2-aminoethyl)carbamoyl)-5-phenylthiophen-2-...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102Z9PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243422(1-(3-carbamoyl-5-(4-(((2-hydroxyethyl)(methyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102Z9PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243530(1-(5-(4-(2-(diethylamino)ethoxy)phenyl)-3-(piperid...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102Z9PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243331(1-(3-carbamoyl-5-(4-(piperidin-1-ylmethyl)phenyl)t...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102Z9PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243423(1-(3-carbamoyl-5-(4-((cyclopentylamino)methyl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102Z9PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243101((S)-1-(5-(4-(methylsulfonamido)phenyl)-3-(piperidi...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102Z9PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243099((S)-1-(5-(4-(dimethylamino)phenyl)-3-(piperidin-3-...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102Z9PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243470(1-(3-carbamoyl-5-(4-((4-methylpiperazin-1-yl)methy...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102Z9PubMed
TargetProtein mono-ADP-ribosyltransferase PARP3(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of PARP3 (unknown origin) using activated DNA as substrate after 1 hr by streptavidin-horseradish peroxidase-based luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2T0JPubMed
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