Compile Data Set for Download or QSAR
Found 130 with Last Name = 'haskins' and Initial = 'k'
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15956(Aminopyridine-Based Inhibitor 18b | N-(4-Amino-5-c...)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Ser/Thr-kinase selectivity assays were performed using a radioactive FlashPlate-based assay platform. Substrate incorporated radioactivity was counte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15908(Aminopyridine-Based Inhibitor 6o | N-(4-Amino-5-cy...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Ser/Thr-kinase selectivity assays were performed using a radioactive FlashPlate-based assay platform. Substrate incorporated radioactivity was counte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15976(Aminopyridine-Based Inhibitor 35 | N-(4-Amino-5-ch...)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Ser/Thr-kinase selectivity assays were performed using a radioactive FlashPlate-based assay platform. Substrate incorporated radioactivity was counte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15939(Aminopyridine-Based Inhibitor 6s | N-(4-amino-5-cy...)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Ser/Thr-kinase selectivity assays were performed using a radioactive FlashPlate-based assay platform. Substrate incorporated radioactivity was counte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15956(Aminopyridine-Based Inhibitor 18b | N-(4-Amino-5-c...)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Ser/Thr-kinase selectivity assays were performed using a radioactive FlashPlate-based assay platform. Substrate incorporated radioactivity was counte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15908(Aminopyridine-Based Inhibitor 6o | N-(4-Amino-5-cy...)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Ser/Thr-kinase selectivity assays were performed using a radioactive FlashPlate-based assay platform. Substrate incorporated radioactivity was counte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15939(Aminopyridine-Based Inhibitor 6s | N-(4-amino-5-cy...)copy SMILEScopy InChI
Affinity DataKi:  9nMAssay Description:Ser/Thr-kinase selectivity assays were performed using a radioactive FlashPlate-based assay platform. Substrate incorporated radioactivity was counte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15976(Aminopyridine-Based Inhibitor 35 | N-(4-Amino-5-ch...)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Ser/Thr-kinase selectivity assays were performed using a radioactive FlashPlate-based assay platform. Substrate incorporated radioactivity was counte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15956(Aminopyridine-Based Inhibitor 18b | N-(4-Amino-5-c...)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:Ser/Thr-kinase selectivity assays were performed using a radioactive FlashPlate-based assay platform. Substrate incorporated radioactivity was counte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15908(Aminopyridine-Based Inhibitor 6o | N-(4-Amino-5-cy...)copy SMILEScopy InChI
Affinity DataKi:  52nMAssay Description:Ser/Thr-kinase selectivity assays were performed using a radioactive FlashPlate-based assay platform. Substrate incorporated radioactivity was counte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15976(Aminopyridine-Based Inhibitor 35 | N-(4-Amino-5-ch...)copy SMILEScopy InChI
Affinity DataKi:  61nMAssay Description:Ser/Thr-kinase selectivity assays were performed using a radioactive FlashPlate-based assay platform. Substrate incorporated radioactivity was counte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15939(Aminopyridine-Based Inhibitor 6s | N-(4-amino-5-cy...)copy SMILEScopy InChI
Affinity DataKi:  72nMAssay Description:Ser/Thr-kinase selectivity assays were performed using a radioactive FlashPlate-based assay platform. Substrate incorporated radioactivity was counte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15907(Aminopyridine-Based Inhibitor 6a | N-(4-Amino-5-cy...)copy SMILEScopy InChI
Affinity DataKi:  190nMAssay Description:Ser/Thr-kinase selectivity assays were performed using a radioactive FlashPlate-based assay platform. Substrate incorporated radioactivity was counte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15907(Aminopyridine-Based Inhibitor 6a | N-(4-Amino-5-cy...)copy SMILEScopy InChI
Affinity DataKi:  440nMAssay Description:Ser/Thr-kinase selectivity assays were performed using a radioactive FlashPlate-based assay platform. Substrate incorporated radioactivity was counte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15907(Aminopyridine-Based Inhibitor 6a | N-(4-Amino-5-cy...)copy SMILEScopy InChI
Affinity DataKi:  520nMAssay Description:Ser/Thr-kinase selectivity assays were performed using a radioactive FlashPlate-based assay platform. Substrate incorporated radioactivity was counte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15968(Aminopyridine-Based Inhibitor 24 | N-(4-Amino-5-cy...)copy SMILEScopy InChI
Affinity DataKi:  550nMAssay Description:Ser/Thr-kinase selectivity assays were performed using a radioactive FlashPlate-based assay platform. Substrate incorporated radioactivity was counte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15968(Aminopyridine-Based Inhibitor 24 | N-(4-Amino-5-cy...)copy SMILEScopy InChI
Affinity DataKi:  1.90E+3nMAssay Description:Ser/Thr-kinase selectivity assays were performed using a radioactive FlashPlate-based assay platform. Substrate incorporated radioactivity was counte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15968(Aminopyridine-Based Inhibitor 24 | N-(4-Amino-5-cy...)copy SMILEScopy InChI
Affinity DataKi:  3.30E+3nMAssay Description:Ser/Thr-kinase selectivity assays were performed using a radioactive FlashPlate-based assay platform. Substrate incorporated radioactivity was counte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15956(Aminopyridine-Based Inhibitor 18b | N-(4-Amino-5-c...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15938(2-(4-Acetylamino-2,5-dimethoxyphenyl)-N-(4-amino-5...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15938(2-(4-Acetylamino-2,5-dimethoxyphenyl)-N-(4-amino-5...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15976(Aminopyridine-Based Inhibitor 35 | N-(4-Amino-5-ch...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15939(Aminopyridine-Based Inhibitor 6s | N-(4-amino-5-cy...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15908(Aminopyridine-Based Inhibitor 6o | N-(4-Amino-5-cy...)copy SMILEScopy InChI
Affinity DataIC50: 45nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15956(Aminopyridine-Based Inhibitor 18b | N-(4-Amino-5-c...)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15941(Aminopyridine-Based Inhibitor 6u | N-(4-Amino-5-cy...)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15952(1-[(4-Amino-5-cyano-6-ethoxypyridin-2-ylcarbamoyl)...)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15976(Aminopyridine-Based Inhibitor 35 | N-(4-Amino-5-ch...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15962(Aminopyridine-Based Inhibitor 20a | N-[4-Amino-5-c...)copy SMILEScopy InChI
Affinity DataIC50: 74nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15940(Aminopyridine-Based Inhibitor 6t | N-(4-Amino-5-cy...)copy SMILEScopy InChI
Affinity DataIC50: 77nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15953(1-[(4-Amino-5-cyano-6-ethoxypyridin-2ylcarbamoyl)m...)copy SMILEScopy InChI
Affinity DataIC50: 87nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15941(Aminopyridine-Based Inhibitor 6u | N-(4-Amino-5-cy...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15963(Aminopyridine-Based Inhibitor 20b | N-[4-Amino-5-c...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15933(Aminopyridine-Based Inhibitor 6l | N-(4-Amino-5-cy...)copy SMILEScopy InChI
Affinity DataIC50: 120nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15953(1-[(4-Amino-5-cyano-6-ethoxypyridin-2ylcarbamoyl)m...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15939(Aminopyridine-Based Inhibitor 6s | N-(4-amino-5-cy...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15948(Aminopyridine-Based Inhibitor 28d | N-(4-Amino-5-c...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15940(Aminopyridine-Based Inhibitor 6t | N-(4-Amino-5-cy...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15908(Aminopyridine-Based Inhibitor 6o | N-(4-Amino-5-cy...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15935(Aminopyridine-Based Inhibitor 6n | N-(4-Amino-5-cy...)copy SMILEScopy InChI
Affinity DataIC50: 180nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15952(1-[(4-Amino-5-cyano-6-ethoxypyridin-2-ylcarbamoyl)...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15932(Aminopyridine-Based Inhibitor 6k | N-(4-Amino-5-cy...)copy SMILEScopy InChI
Affinity DataIC50: 190nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15934(Aminopyridine-Based Inhibitor 6m | N-(4-Amino-5-cy...)copy SMILEScopy InChI
Affinity DataIC50: 210nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15962(Aminopyridine-Based Inhibitor 20a | N-[4-Amino-5-c...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15933(Aminopyridine-Based Inhibitor 6l | N-(4-Amino-5-cy...)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15950(Aminopyridine-Based Inhibitor 30 | N-(4-Amino-5-cy...)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15963(Aminopyridine-Based Inhibitor 20b | N-[4-Amino-5-c...)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15935(Aminopyridine-Based Inhibitor 6n | N-(4-Amino-5-cy...)copy SMILEScopy InChI
Affinity DataIC50: 274nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15928(Aminopyridine-Based Inhibitor 6g | N-(4-Amino-5-cy...)copy SMILEScopy InChI
Affinity DataIC50: 300nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15951(Aminopyridine-Based Inhibitor 31 | N-(4-Amino-5-cy...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26WDXPubMed
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