Compile Data Set for Download or QSAR
Found 108 with Last Name = 'holden' and Initial = 'k'
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Smith Kline& French Laboratories

Curated by ChEMBL
LigandPNGBDBM13014(7,8-Dichloro-1,2,3,4-tetrahydro-isoquinoline; hydr...)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Binding affinity for phenylethanolamine N-methyl-transferase was determined.More data for this Ligand-Target Pair
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM31046(3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphe...)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Binding affinity against alpha-2-adrenergic receptor using 10 nM [3H]yohimbine in human platelet membranes from three separate experiments using 10 i...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125VWHPubMedDrugBank
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50225305(CHEMBL433730)copy SMILEScopy InChI
Affinity DataKi:  6.10nMAssay Description:Binding affinity against alpha-2-adrenergic receptor using 10 nM [3H]yohimbine in human platelet membranes from three separate experiments using 10 i...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125VWHPubMed
TargetPhenylethanolamine N-methyltransferase(Bos taurus (bovine))
Smith Kline& French Laboratories

Curated by ChEMBL
LigandPNGBDBM50018237(6,7,8,9-Tetrahydro-3-thia-1,2,8-triaza-cyclopenta[...)copy SMILEScopy InChI
Affinity DataKi:  8nMAssay Description:Binding affinity for phenylethanolamine N-methyl-transferase was determined.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QZ2BJVPubMed
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM66983(6-chloranyl-3-methyl-1,2,4,5-tetrahydro-3-benzazep...)copy SMILEScopy InChI
Affinity DataKi:  17nMAssay Description:Binding affinity against alpha-2-adrenergic receptor using 10 nM [3H]yohimbine in human platelet membranes from three separate experiments using 10 i...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125VWHPubMed
TargetAdenylate cyclase type 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50222264(CHEMBL552736)copy SMILEScopy InChI
Affinity DataKi:  22nMAssay Description:Inhibitory activity against Dopamine sensitive adenylate cyclase in ratsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RV0QWDPubMed
TargetAdenylate cyclase type 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50222266(CHEMBL369006)copy SMILEScopy InChI
Affinity DataKi:  33nMAssay Description:Inhibitory activity against Dopamine sensitive adenylate cyclase in ratsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RV0QWDPubMed
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50225307(CHEMBL170660)copy SMILEScopy InChI
Affinity DataKi:  48nMAssay Description:Binding affinity against alpha-2-adrenergic receptor using 10 nM [3H]yohimbine in human platelet membranes from four to five separate experiments usi...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125VWHPubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University of California

Curated by ChEMBL
LigandPNGBDBM50427863(CHEMBL2326360)copy SMILEScopy InChI
Affinity DataKi:  53nMAssay Description:Inhibition of rat nNOSMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University of California

Curated by ChEMBL
LigandPNGBDBM50341678(6,6'-(2,2'-(5-Amino-1,3-phenylene)bis(ethane-2,1di...)copy SMILEScopy InChI
Affinity DataKi:  85nMAssay Description:Inhibition of rat nNOSMore data for this Ligand-Target Pair
TargetAdenylate cyclase type 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50001888((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)copy SMILEScopy InChI
Affinity DataKi:  118nMAssay Description:Inhibitory activity against Dopamine sensitive adenylate cyclase in ratsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RV0QWDPubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University of California

Curated by ChEMBL
LigandPNGBDBM50060408(CHEMBL3394386)copy SMILEScopy InChI
Affinity DataKi:  196nMAssay Description:Inhibition of rat nNOSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833TP5PubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University of California

Curated by ChEMBL
LigandPNGBDBM50060406(CHEMBL3394388)copy SMILEScopy InChI
Affinity DataKi:  220nMAssay Description:Inhibition of rat nNOSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833TP5PubMed
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50225306(CHEMBL355527)copy SMILEScopy InChI
Affinity DataKi:  232nMAssay Description:Binding affinity against alpha-2-adrenergic receptor using 10 nM [3H]yohimbine in preparations in human platelet membranes from three separate experi...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125VWHPubMed
TargetAdenylate cyclase type 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50222265(CHEMBL541633)copy SMILEScopy InChI
Affinity DataKi:  250nMAssay Description:Inhibitory activity against Dopamine sensitive adenylate cyclase in ratsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RV0QWDPubMed
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50225308(CHEMBL173581)copy SMILEScopy InChI
Affinity DataKi:  338nMAssay Description:Binding affinity against alpha-2-adrenergic receptor using 10 nM [3H]yohimbine in human platelet membranes from three separate experiments using 10 i...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125VWHPubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
The University of Iowa

Curated by ChEMBL
LigandPNGBDBM50185615((2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-6a,1...)copy SMILEScopy InChI
Affinity DataKi:  410nMAssay Description:Displacement of [125I]IOXY from human kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SZKPubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University of California

Curated by ChEMBL
LigandPNGBDBM50427865(CHEMBL2326358)copy SMILEScopy InChI
Affinity DataKi:  540nMAssay Description:Inhibition of rat nNOSMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University of California

Curated by ChEMBL
LigandPNGBDBM50448828(CHEMBL3128242)copy SMILEScopy InChI
Affinity DataKi:  819nMAssay Description:Inhibition of rat nNOSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833TP5PubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
The University of Iowa

Curated by ChEMBL
LigandPNGBDBM50185617((2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-6a,1...)copy SMILEScopy InChI
Affinity DataKi:  840nMAssay Description:Displacement of [125I]IOXY from human kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SZKPubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University of California

Curated by ChEMBL
LigandPNGBDBM50060407(CHEMBL3394387)copy SMILEScopy InChI
Affinity DataKi:  1.27E+3nMAssay Description:Inhibition of rat nNOSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833TP5PubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
University of California

Curated by ChEMBL
LigandPNGBDBM50060407(CHEMBL3394387)copy SMILEScopy InChI
Affinity DataKi:  1.56E+3nMAssay Description:Inhibition of bovine eNOSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833TP5PubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
The University of Iowa

Curated by ChEMBL
LigandPNGBDBM50185616((2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-2-(1...)copy SMILEScopy InChI
Affinity DataKi:  1.62E+3nMAssay Description:Displacement of [125I]IOXY from human kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SZKPubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University of California

Curated by ChEMBL
LigandPNGBDBM50341678(6,6'-(2,2'-(5-Amino-1,3-phenylene)bis(ethane-2,1di...)copy SMILEScopy InChI
Affinity DataKi:  3.40E+3nMAssay Description:Inhibition of mouse iNOSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833TP5PubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
University of California

Curated by ChEMBL
LigandPNGBDBM50341678(6,6'-(2,2'-(5-Amino-1,3-phenylene)bis(ethane-2,1di...)copy SMILEScopy InChI
Affinity DataKi:  4.95E+3nMAssay Description:Inhibition of bovine eNOSMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University of California

Curated by ChEMBL
LigandPNGBDBM50448828(CHEMBL3128242)copy SMILEScopy InChI
Affinity DataKi:  5.20E+3nMAssay Description:Inhibition of mouse iNOSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833TP5PubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University of California

Curated by ChEMBL
LigandPNGBDBM50427863(CHEMBL2326360)copy SMILEScopy InChI
Affinity DataKi:  6.31E+3nMAssay Description:Inhibition of mouse iNOSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833TP5PubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University of California

Curated by ChEMBL
LigandPNGBDBM50060406(CHEMBL3394388)copy SMILEScopy InChI
Affinity DataKi:  7.10E+3nMAssay Description:Inhibition of mouse iNOSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833TP5PubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
The University of Iowa

Curated by ChEMBL
LigandPNGBDBM50185614(CHEMBL377182 | methyl 2-((2S,4aR,6aR,7R,9S,10aS,10...)copy SMILEScopy InChI
Affinity DataKi:  8.53E+3nMAssay Description:Displacement of [125I]IOXY from human kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SZKPubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
The University of Iowa

Curated by ChEMBL
LigandPNGBDBM50185614(CHEMBL377182 | methyl 2-((2S,4aR,6aR,7R,9S,10aS,10...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]IOXY from human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SZKPubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
The University of Iowa

Curated by ChEMBL
LigandPNGBDBM50185617((2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-6a,1...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]IOXY from human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SZKPubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
The University of Iowa

Curated by ChEMBL
LigandPNGBDBM50185617((2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-6a,1...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]IOXY from human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SZKPubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
The University of Iowa

Curated by ChEMBL
LigandPNGBDBM50185616((2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-2-(1...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]IOXY from human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SZKPubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
The University of Iowa

Curated by ChEMBL
LigandPNGBDBM50185614(CHEMBL377182 | methyl 2-((2S,4aR,6aR,7R,9S,10aS,10...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]IOXY from human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SZKPubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
The University of Iowa

Curated by ChEMBL
LigandPNGBDBM50185615((2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-6a,1...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]IOXY from human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SZKPubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
The University of Iowa

Curated by ChEMBL
LigandPNGBDBM50185615((2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-6a,1...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]IOXY from human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SZKPubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
The University of Iowa

Curated by ChEMBL
LigandPNGBDBM50185616((2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-2-(1...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]IOXY from human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SZKPubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
University of California

Curated by ChEMBL
LigandPNGBDBM50448828(CHEMBL3128242)copy SMILEScopy InChI
Affinity DataKi:  1.01E+4nMAssay Description:Inhibition of bovine eNOSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833TP5PubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
University of California

Curated by ChEMBL
LigandPNGBDBM50427863(CHEMBL2326360)copy SMILEScopy InChI
Affinity DataKi:  1.17E+4nMAssay Description:Inhibition of bovine eNOSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833TP5PubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
University of California

Curated by ChEMBL
LigandPNGBDBM50060408(CHEMBL3394386)copy SMILEScopy InChI
Affinity DataKi:  1.18E+4nMAssay Description:Inhibition of bovine eNOSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833TP5PubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
University of California

Curated by ChEMBL
LigandPNGBDBM50427865(CHEMBL2326358)copy SMILEScopy InChI
Affinity DataKi:  1.21E+4nMAssay Description:Inhibition of bovine eNOSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833TP5PubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University of California

Curated by ChEMBL
LigandPNGBDBM50060407(CHEMBL3394387)copy SMILEScopy InChI
Affinity DataKi:  1.28E+4nMAssay Description:Inhibition of mouse iNOSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833TP5PubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University of California

Curated by ChEMBL
LigandPNGBDBM50060408(CHEMBL3394386)copy SMILEScopy InChI
Affinity DataKi:  1.44E+4nMAssay Description:Inhibition of mouse iNOSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833TP5PubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University of California

Curated by ChEMBL
LigandPNGBDBM50427865(CHEMBL2326358)copy SMILEScopy InChI
Affinity DataKi:  3.25E+4nMAssay Description:Inhibition of mouse iNOSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833TP5PubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
University of California

Curated by ChEMBL
LigandPNGBDBM50060406(CHEMBL3394388)copy SMILEScopy InChI
Affinity DataKi:  5.27E+4nMAssay Description:Inhibition of bovine eNOSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833TP5PubMed
TargetAdenylate cyclase type 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50222264(CHEMBL552736)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibitory concentration against Dopamine sensitive adenylate cyclase in ratsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RV0QWDPubMed
TargetAdenylate cyclase type 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50222266(CHEMBL369006)copy SMILEScopy InChI
Affinity DataIC50: 360nMAssay Description:Inhibitory concentration against Dopamine sensitive adenylate cyclase in ratsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RV0QWDPubMed
LigandPNGBDBM50001888((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibitory concentration against Dopamine sensitive adenylate cyclase in ratsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RV0QWDPubMed
TargetAdenylate cyclase type 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50222265(CHEMBL541633)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibitory concentration against Dopamine sensitive adenylate cyclase in ratsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RV0QWDPubMed
TargetTyrosine-protein kinase transforming protein Abl(Abelson murine leukemia virus)
Smith Kline& French Laboratories

Curated by ChEMBL
LigandPNGBDBM50292494(CHEMBL485064 | {[(2R,3S,4R,5R)-5-(6-amino-9H-purin...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of p60v-abl tyrosine kinase from Abelson murine leukemia virusMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2833SMVPubMed
Displayed 1 to 50 (of 108 total ) | Next | Last >>
Jump to: