Compile Data Set for Download or QSAR
Found 323 with Last Name = 'horiuchi' and Initial = 'k'
TargetActivin receptor type-1(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50544399(CHEMBL4638273)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GV3PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50544408(CHEMBL4641207)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GV3PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50544414(CHEMBL4641530)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GV3PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50544419(CHEMBL4647724)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GV3PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50544418(CHEMBL4648102)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GV3PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50528194(CHEMBL4517408)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Competitive displacement of PBI-6908 from nanoluciferase-fused ALK2 G328V mutant (unknown origin) expressed in HEK293 cells incubated for 2 hrs by Na...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetActivin receptor type-1(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50528194(CHEMBL4517408)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Competitive displacement of PBI-6908 from nanoluciferase-fused ALK2 Q207D mutant (unknown origin) expressed in HEK293 cells incubated for 2 hrs by Na...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetActivin receptor type-1(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50544413(CHEMBL4633241)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetActivin receptor type-1(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50544404(CHEMBL4644571)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GV3PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50141397(4-({3-[(Z)-2-Amino-2-(2-amino-phenylsulfanyl)-1-cy...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibitory potency against mitogen activated protein kinase kinase kinase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H131F0PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50544405(CHEMBL4634857)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GV3PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50141406((Z)-3-Amino-3-(2-amino-phenylsulfanyl)-2-{3-[(2,4-...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibitory potency against mitogen activated protein kinase kinase kinase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H131F0PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50141412((Z)-3-Amino-3-(2-amino-phenylsulfanyl)-2-{3-[hydro...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibitory potency against mitogen activated protein kinase kinase kinase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H131F0PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50141438(4-({3-[(Z)-2-Amino-1-cyano-2-(2-hydroxy-phenylsulf...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibitory potency against mitogen activated protein kinase kinase kinase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H131F0PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50528194(CHEMBL4517408)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of ALK2 G328V mutant (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetActivin receptor type-1(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50544403(CHEMBL4643265)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GV3PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50528194(CHEMBL4517408)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human ALK2 R206H mutant using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetActivin receptor type-1(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50544412(CHEMBL4635321)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetActivin receptor type-1(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50544402(CHEMBL4646278)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GV3PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50141410((Z)-3-Amino-3-(2-amino-phenylsulfanyl)-2-[3-(hydro...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibitory potency against mitogen activated protein kinase kinase kinase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H131F0PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50528194(CHEMBL4517408)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Competitive displacement of PBI-6908 from nanoluciferase-fused ALK2 R206H mutant (unknown origin) expressed in HEK293 cells incubated for 2 hrs by Na...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetActivin receptor type-1(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50528194(CHEMBL4517408)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of ALK2 R258G mutant (unknown origin) by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50141441(3-({3-[(Z)-2-Amino-2-(2-amino-phenylsulfanyl)-1-cy...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibitory potency against mitogen activated protein kinase kinase kinase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H131F0PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50528194(CHEMBL4517408)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetActivin receptor type-1(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50544416(CHEMBL4639700)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GV3PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50544415(CHEMBL4646444)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GV3PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50141404(4-({3-[(Z)-2-Amino-2-(2-amino-phenylsulfanyl)-1-cy...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibitory potency against mitogen activated protein kinase kinase kinase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H131F0PubMed
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50528194(CHEMBL4517408)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of human ALK1 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GV3PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50544396(CHEMBL4633121)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GV3PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50544399(CHEMBL4638273)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Competitive displacement of PBI-6908 from nanoluciferase-fused ALK2 (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET NanoGl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GV3PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50544397(CHEMBL4642165)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GV3PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50528194(CHEMBL4517408)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Competitive displacement of PBI-6908 from nanoluciferase-fused ALK2 G356D mutant (unknown origin) expressed in HEK293 cells incubated for 2 hrs by Na...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetActivin receptor type-1(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50544411(CHEMBL4648735)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GV3PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50141400((Z)-3-Amino-3-(2-amino-phenylsulfanyl)-2-{3-[hydro...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibitory potency against mitogen activated protein kinase kinase kinase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H131F0PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50141426((Z)-3-Amino-3-(2-amino-phenylsulfanyl)-2-[3-(hydro...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibitory potency against mitogen activated protein kinase kinase kinase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H131F0PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50544406(CHEMBL4647991)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GV3PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50141417((Z)-3-Amino-3-(2-amino-phenylsulfanyl)-2-[3-(hydro...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibitory potency against mitogen activated protein kinase kinase kinase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H131F0PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50544401(CHEMBL4636120)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GV3PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50544417(CHEMBL4638893)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GV3PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50544407(CHEMBL4648707)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GV3PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50141440((Z)-3-Amino-3-(2-amino-phenylsulfanyl)-2-[3-(hydro...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibitory potency against mitogen activated protein kinase kinase kinase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H131F0PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50141427((Z)-3-Amino-2-{3-[hydroxy-(3-nitro-phenyl)-methyl]...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibitory potency against mitogen activated protein kinase kinase kinase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H131F0PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50141401((Z)-3-Amino-3-(2-amino-phenylsulfanyl)-2-[3-(hydro...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibitory potency against mitogen activated protein kinase kinase kinase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H131F0PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50141399((Z)-3-Amino-3-(2-amino-phenylsulfanyl)-2-{3-[(2,3-...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibitory potency against mitogen activated protein kinase kinase kinase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H131F0PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50544410(CHEMBL4642622)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GV3PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50544413(CHEMBL4633241)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Competitive displacement of PBI-6908 from nanoluciferase-fused ALK2 (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET NanoGl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetActivin receptor type-1(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50544409(CHEMBL4638544)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GV3PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50141418((Z)-3-Amino-3-(2-amino-phenylsulfanyl)-2-[3-(hydro...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibitory potency against mitogen activated protein kinase kinase kinase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H131F0PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50544418(CHEMBL4648102)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Competitive displacement of PBI-6908 from nanoluciferase-fused ALK2 (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET NanoGl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GV3PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50544396(CHEMBL4633121)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Competitive displacement of PBI-6908 from nanoluciferase-fused ALK2 (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET NanoGl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GV3PubMed
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