Compile Data Set for Download or QSAR
Found 242 with Last Name = 'huber' and Initial = 'k'
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig Maximilians-Universit£t M£nchen

Curated by ChEMBL
LigandPNGBDBM50039251((R)-1-(4,4-bis(3-methylthiophen-2-yl)but-3-enyl)pi...)copy SMILEScopy InChI
Affinity DataKi:  37nMAssay Description:Inhibition of NO711 binding to mouse GAT1 expressed in HEK293 cell membranes assessed as reduction in NO711 binding at incubated for 4 hrs in presenc...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig Maximilians-Universit£t M£nchen

Curated by ChEMBL
LigandPNGBDBM50510628(CHEMBL4464729)copy SMILEScopy InChI
Affinity DataKi:  389nMAssay Description:Inhibition of NO711 binding to mouse GAT1 expressed in HEK293 cell membranes assessed as reduction in NO711 binding at incubated for 4 hrs in presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD227RPubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig Maximilians-Universit£t M£nchen

Curated by ChEMBL
LigandPNGBDBM50510627(CHEMBL4587609)copy SMILEScopy InChI
Affinity DataKi:  407nMAssay Description:Inhibition of NO711 binding to mouse GAT1 expressed in HEK293 cell membranes assessed as reduction in NO711 binding at incubated for 4 hrs in presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD227RPubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig Maximilians-Universit£t M£nchen

Curated by ChEMBL
LigandPNGBDBM50510629(CHEMBL4539697)copy SMILEScopy InChI
Affinity DataKi:  692nMAssay Description:Inhibition of NO711 binding to mouse GAT1 expressed in HEK293 cell membranes assessed as reduction in NO711 binding at incubated for 4 hrs in presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD227RPubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.

Curated by ChEMBL
LigandPNGBDBM50255566(CHEMBL4094252)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Binding affinity to recombinant human full length N-terminal His tagged-MTH1 expressed in Escherichia coli at 3 mM by isothermal titration calorimetr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8V9QPubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.

Curated by ChEMBL
LigandPNGBDBM50255622(CHEMBL4067896)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Binding affinity to recombinant human full length N-terminal His tagged-MTH1 expressed in Escherichia coli at 3 mM by isothermal titration calorimetr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8V9QPubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.

Curated by ChEMBL
LigandPNGBDBM50255581(CHEMBL4073623)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human full length MTH1 using 8-Oxo-2-dGTP as substrate preincubated for 15 mins followed substrate addition measured after 1 hr by PPil...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8V9QPubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.

Curated by ChEMBL
LigandPNGBDBM50255568(CHEMBL4091768)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human full length MTH1 using 8-Oxo-2-dGTP as substrate preincubated for 15 mins followed substrate addition measured after 1 hr by PPil...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8V9QPubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.

Curated by ChEMBL
LigandPNGBDBM50255582(CHEMBL4078783)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Binding affinity to recombinant human full length N-terminal His tagged-MTH1 expressed in Escherichia coli at 3 mM by isothermal titration calorimetr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8V9QPubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.

Curated by ChEMBL
LigandPNGBDBM50255624(CHEMBL4101983)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Binding affinity to recombinant human full length N-terminal His tagged-MTH1 expressed in Escherichia coli at 3 mM by isothermal titration calorimetr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8V9QPubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.

Curated by ChEMBL
LigandPNGBDBM50255598(CHEMBL4064004)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Binding affinity to recombinant human full length N-terminal His tagged-MTH1 expressed in Escherichia coli at 3 mM by isothermal titration calorimetr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8V9QPubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.

Curated by ChEMBL
LigandPNGBDBM50255603(CHEMBL4083992)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Binding affinity to recombinant human full length N-terminal His tagged-MTH1 expressed in Escherichia coli at 3 mM by isothermal titration calorimetr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8V9QPubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.

Curated by ChEMBL
LigandPNGBDBM50255621(CHEMBL4070624)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Binding affinity to recombinant human full length N-terminal His tagged-MTH1 expressed in Escherichia coli at 3 mM by isothermal titration calorimetr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8V9QPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50387298(CHEMBL2048872)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human PIM1 using full-length BAD as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4M5VPubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.

Curated by ChEMBL
LigandPNGBDBM50255583(CHEMBL4096813)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Binding affinity to recombinant human full length N-terminal His tagged-MTH1 expressed in Escherichia coli at 3 mM by isothermal titration calorimetr...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.

Curated by ChEMBL
LigandPNGBDBM50255623(CHEMBL4072758)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Binding affinity to recombinant human full length N-terminal His tagged-MTH1 expressed in Escherichia coli at 3 mM by isothermal titration calorimetr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8V9QPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50248903(CHEMBL4060012)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4M5VPubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50387298(CHEMBL2048872)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human PIM3 using full-length BAD as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4M5VPubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.

Curated by ChEMBL
LigandPNGBDBM50255585(CHEMBL4094381)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Binding affinity to recombinant human full length N-terminal His tagged-MTH1 expressed in Escherichia coli at 3 mM by isothermal titration calorimetr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8V9QPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50248920(CHEMBL4079975)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4M5VPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50248897(CHEMBL4061984)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4M5VPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50248893(CHEMBL4104431)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4M5VPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50248921(CHEMBL4096030)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4M5VPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50248898(CHEMBL4083726)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4M5VPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50436459(CHEMBL2396661)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of P13Kalpha (unknown origin)More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.

Curated by ChEMBL
LigandPNGBDBM50255615(CHEMBL4061204)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Binding affinity to recombinant human full length N-terminal His tagged-MTH1 expressed in Escherichia coli at 3 mM by isothermal titration calorimetr...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.

Curated by ChEMBL
LigandPNGBDBM50255584(CHEMBL4089106)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Binding affinity to recombinant human full length N-terminal His tagged-MTH1 expressed in Escherichia coli at 3 mM by isothermal titration calorimetr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8V9QPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50387298(CHEMBL2048872)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human PIM2 using full-length BAD as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4M5VPubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50505576(CHEMBL4458252)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of G9a (unknown origin) by scintillation proximity AssayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7S2SPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50248863(CHEMBL4087322)copy SMILEScopy InChI
Affinity DataIC50: 6.70nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4M5VPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50248904(CHEMBL4069560)copy SMILEScopy InChI
Affinity DataIC50: 6.70nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4M5VPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50248892(CHEMBL4074078)copy SMILEScopy InChI
Affinity DataIC50: 6.80nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4M5VPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50248894(CHEMBL4060062)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4M5VPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50364776(CHEMBL1952141 | CHEMBL1952329)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged PIM1 expressed in Escherichia coli using LKKRNRTLTV as substrate measured after 40 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4M5VPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50248899(CHEMBL4069566)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4M5VPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50248860(CHEMBL4077499)copy SMILEScopy InChI
Affinity DataIC50: 9.20nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4M5VPubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.

Curated by ChEMBL
LigandPNGBDBM50255617(CHEMBL4095468)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Binding affinity to recombinant human full length N-terminal His tagged-MTH1 expressed in Escherichia coli at 3 mM by isothermal titration calorimetr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8V9QPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50248922(CHEMBL4077328)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4M5VPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50248901(CHEMBL4075979)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4M5VPubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.

Curated by ChEMBL
LigandPNGBDBM50255610(CHEMBL4079884)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Binding affinity to recombinant human full length N-terminal His tagged-MTH1 expressed in Escherichia coli at 3 mM by isothermal titration calorimetr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8V9QPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50248923(CHEMBL4075290)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4M5VPubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.

Curated by ChEMBL
LigandPNGBDBM50255618(CHEMBL4104130)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Binding affinity to recombinant human full length N-terminal His tagged-MTH1 expressed in Escherichia coli at 3 mM by isothermal titration calorimetr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50248900(CHEMBL4075977)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4M5VPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50248895(CHEMBL4088298)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4M5VPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50248864(CHEMBL4090574)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4M5VPubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.

Curated by ChEMBL
LigandPNGBDBM50255567(CHEMBL4066892)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Binding affinity to recombinant human full length N-terminal His tagged-MTH1 expressed in Escherichia coli at 3 mM by isothermal titration calorimetr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8V9QPubMed
TargetSpindlin-1(Homo sapiens)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50505574(CHEMBL4451634)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Displacement of trimethylated biotinylated histone H3 peptide from recombinant human His-tagged SPIN1 (26 to 262 residues) expressed in Escherichia c...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50248865(CHEMBL4069055)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4M5VPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50248896(CHEMBL4068718)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4M5VPubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
CeMM-Research Center for Molecular Medicine of the Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50178769((+/-)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-c...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of human recombinant GST-tagged SIRT1 expressed in 293T cells by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2251JJ4PubMed
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