TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig Maximilians-Universit£t M£nchen
Curated by ChEMBL
Ludwig Maximilians-Universit£t M£nchen
Curated by ChEMBL
Affinity DataKi: 37nMAssay Description:Inhibition of NO711 binding to mouse GAT1 expressed in HEK293 cell membranes assessed as reduction in NO711 binding at incubated for 4 hrs in presenc...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig Maximilians-Universit£t M£nchen
Curated by ChEMBL
Ludwig Maximilians-Universit£t M£nchen
Curated by ChEMBL
Affinity DataKi: 389nMAssay Description:Inhibition of NO711 binding to mouse GAT1 expressed in HEK293 cell membranes assessed as reduction in NO711 binding at incubated for 4 hrs in presenc...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig Maximilians-Universit£t M£nchen
Curated by ChEMBL
Ludwig Maximilians-Universit£t M£nchen
Curated by ChEMBL
Affinity DataKi: 407nMAssay Description:Inhibition of NO711 binding to mouse GAT1 expressed in HEK293 cell membranes assessed as reduction in NO711 binding at incubated for 4 hrs in presenc...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig Maximilians-Universit£t M£nchen
Curated by ChEMBL
Ludwig Maximilians-Universit£t M£nchen
Curated by ChEMBL
Affinity DataKi: 692nMAssay Description:Inhibition of NO711 binding to mouse GAT1 expressed in HEK293 cell membranes assessed as reduction in NO711 binding at incubated for 4 hrs in presenc...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.
Curated by ChEMBL
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Binding affinity to recombinant human full length N-terminal His tagged-MTH1 expressed in Escherichia coli at 3 mM by isothermal titration calorimetr...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.
Curated by ChEMBL
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Binding affinity to recombinant human full length N-terminal His tagged-MTH1 expressed in Escherichia coli at 3 mM by isothermal titration calorimetr...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.
Curated by ChEMBL
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human full length MTH1 using 8-Oxo-2-dGTP as substrate preincubated for 15 mins followed substrate addition measured after 1 hr by PPil...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.
Curated by ChEMBL
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human full length MTH1 using 8-Oxo-2-dGTP as substrate preincubated for 15 mins followed substrate addition measured after 1 hr by PPil...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.
Curated by ChEMBL
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Binding affinity to recombinant human full length N-terminal His tagged-MTH1 expressed in Escherichia coli at 3 mM by isothermal titration calorimetr...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.
Curated by ChEMBL
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Binding affinity to recombinant human full length N-terminal His tagged-MTH1 expressed in Escherichia coli at 3 mM by isothermal titration calorimetr...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.
Curated by ChEMBL
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Binding affinity to recombinant human full length N-terminal His tagged-MTH1 expressed in Escherichia coli at 3 mM by isothermal titration calorimetr...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.
Curated by ChEMBL
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Binding affinity to recombinant human full length N-terminal His tagged-MTH1 expressed in Escherichia coli at 3 mM by isothermal titration calorimetr...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.
Curated by ChEMBL
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Binding affinity to recombinant human full length N-terminal His tagged-MTH1 expressed in Escherichia coli at 3 mM by isothermal titration calorimetr...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human PIM1 using full-length BAD as substrateMore data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.
Curated by ChEMBL
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Binding affinity to recombinant human full length N-terminal His tagged-MTH1 expressed in Escherichia coli at 3 mM by isothermal titration calorimetr...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.
Curated by ChEMBL
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Binding affinity to recombinant human full length N-terminal His tagged-MTH1 expressed in Escherichia coli at 3 mM by isothermal titration calorimetr...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human PIM3 using full-length BAD as substrateMore data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.
Curated by ChEMBL
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Binding affinity to recombinant human full length N-terminal His tagged-MTH1 expressed in Escherichia coli at 3 mM by isothermal titration calorimetr...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of P13Kalpha (unknown origin)More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.
Curated by ChEMBL
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Binding affinity to recombinant human full length N-terminal His tagged-MTH1 expressed in Escherichia coli at 3 mM by isothermal titration calorimetr...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.
Curated by ChEMBL
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Binding affinity to recombinant human full length N-terminal His tagged-MTH1 expressed in Escherichia coli at 3 mM by isothermal titration calorimetr...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human PIM2 using full-length BAD as substrateMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of G9a (unknown origin) by scintillation proximity AssayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
Affinity DataIC50: 6.70nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
Affinity DataIC50: 6.70nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
Affinity DataIC50: 6.80nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged PIM1 expressed in Escherichia coli using LKKRNRTLTV as substrate measured after 40 ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
Affinity DataIC50: 9.20nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.
Curated by ChEMBL
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Binding affinity to recombinant human full length N-terminal His tagged-MTH1 expressed in Escherichia coli at 3 mM by isothermal titration calorimetr...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.
Curated by ChEMBL
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Binding affinity to recombinant human full length N-terminal His tagged-MTH1 expressed in Escherichia coli at 3 mM by isothermal titration calorimetr...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.
Curated by ChEMBL
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Binding affinity to recombinant human full length N-terminal His tagged-MTH1 expressed in Escherichia coli at 3 mM by isothermal titration calorimetr...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.
Curated by ChEMBL
Sprint Bioscience AB, Novum , 14157 Huddinge , Sweden.
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Binding affinity to recombinant human full length N-terminal His tagged-MTH1 expressed in Escherichia coli at 3 mM by isothermal titration calorimetr...More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Displacement of trimethylated biotinylated histone H3 peptide from recombinant human His-tagged SPIN1 (26 to 262 residues) expressed in Escherichia c...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
CeMM-Research Center for Molecular Medicine of the Austrian Academy of Sciences
Curated by ChEMBL
CeMM-Research Center for Molecular Medicine of the Austrian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of human recombinant GST-tagged SIRT1 expressed in 293T cells by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
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