Compile Data Set for Download or QSAR
Found 201 with Last Name = 'iikubo' and Initial = 'k'
TargetTyrosine-protein kinase receptor(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144297(US8969336, 388)copy SMILEScopy InChI
Affinity DataIC50: 0.170nMAssay Description:A recombinant retrovirus was created from expression plasmid FLAG-EML4-ALKv1/pMX-iresCD8 in which cDNA for EMLA-ALK fusion protein v1 was integrated,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetTyrosine-protein kinase receptor(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144299(US8969336, 392)copy SMILEScopy InChI
Affinity DataIC50: 0.210nMAssay Description:A recombinant retrovirus was created from expression plasmid FLAG-EML4-ALKv1/pMX-iresCD8 in which cDNA for EMLA-ALK fusion protein v1 was integrated,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetTyrosine-protein kinase receptor(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144298(US8969336, 391)copy SMILEScopy InChI
Affinity DataIC50: 0.220nMAssay Description:A recombinant retrovirus was created from expression plasmid FLAG-EML4-ALKv1/pMX-iresCD8 in which cDNA for EMLA-ALK fusion protein v1 was integrated,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetTyrosine-protein kinase receptor(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144295(US8969336, 383)copy SMILEScopy InChI
Affinity DataIC50: 0.230nMAssay Description:A recombinant retrovirus was created from expression plasmid FLAG-EML4-ALKv1/pMX-iresCD8 in which cDNA for EMLA-ALK fusion protein v1 was integrated,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144323(US8969336, 567)copy SMILEScopy InChI
Affinity DataIC50: 0.230nMAssay Description:A partial protein of only a kinase domain of ROS protein was purchased from Carna Biosciences Inc., Japan, and tests were conducted as in Test Exampl...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetTyrosine-protein kinase receptor(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144293(US8969336, 377)copy SMILEScopy InChI
Affinity DataIC50: 0.240nMAssay Description:A recombinant retrovirus was created from expression plasmid FLAG-EML4-ALKv1/pMX-iresCD8 in which cDNA for EMLA-ALK fusion protein v1 was integrated,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetTyrosine-protein kinase receptor(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144294(US8969336, 378)copy SMILEScopy InChI
Affinity DataIC50: 0.260nMAssay Description:A recombinant retrovirus was created from expression plasmid FLAG-EML4-ALKv1/pMX-iresCD8 in which cDNA for EMLA-ALK fusion protein v1 was integrated,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetTyrosine-protein kinase receptor(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144303(US8969336, 459)copy SMILEScopy InChI
Affinity DataIC50: 0.260nMAssay Description:A recombinant retrovirus was created from expression plasmid FLAG-EML4-ALKv1/pMX-iresCD8 in which cDNA for EMLA-ALK fusion protein v1 was integrated,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetTyrosine-protein kinase receptor(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144296(US8969336, 387)copy SMILEScopy InChI
Affinity DataIC50: 0.260nMAssay Description:A recombinant retrovirus was created from expression plasmid FLAG-EML4-ALKv1/pMX-iresCD8 in which cDNA for EMLA-ALK fusion protein v1 was integrated,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144318(US8969336, 553 | US8969336, 580)copy SMILEScopy InChI
Affinity DataIC50: 0.290nMAssay Description:A partial protein of only a kinase domain of ROS protein was purchased from Carna Biosciences Inc., Japan, and tests were conducted as in Test Exampl...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetTyrosine-protein kinase receptor(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144290(US8969336, 355)copy SMILEScopy InChI
Affinity DataIC50: 0.330nMAssay Description:A recombinant retrovirus was created from expression plasmid FLAG-EML4-ALKv1/pMX-iresCD8 in which cDNA for EMLA-ALK fusion protein v1 was integrated,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetTyrosine-protein kinase receptor(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144301(US8969336, 406)copy SMILEScopy InChI
Affinity DataIC50: 0.340nMAssay Description:A recombinant retrovirus was created from expression plasmid FLAG-EML4-ALKv1/pMX-iresCD8 in which cDNA for EMLA-ALK fusion protein v1 was integrated,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144328(US8969336, 572)copy SMILEScopy InChI
Affinity DataIC50: 0.340nMAssay Description:A partial protein of only a kinase domain of FLT3 protein was purchased from Carna Biosciences Inc., Japan, and tests were conducted as in Test Examp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144325(US8969336, 569)copy SMILEScopy InChI
Affinity DataIC50: 0.350nMAssay Description:A partial protein of only a kinase domain of FLT3 protein was purchased from Carna Biosciences Inc., Japan, and tests were conducted as in Test Examp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144317(US8969336, 550 | US8969336, 579)copy SMILEScopy InChI
Affinity DataIC50: 0.360nMAssay Description:A partial protein of only a kinase domain of FLT3 protein was purchased from Carna Biosciences Inc., Japan, and tests were conducted as in Test Examp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144309(US8969336, 512 | US8969336, 574)copy SMILEScopy InChI
Affinity DataIC50: 0.360nMAssay Description:A partial protein of only a kinase domain of FLT3 protein was purchased from Carna Biosciences Inc., Japan, and tests were conducted as in Test Examp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetTyrosine-protein kinase receptor(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144285(US8969336, 340)copy SMILEScopy InChI
Affinity DataIC50: 0.370nMAssay Description:A recombinant retrovirus was created from expression plasmid FLAG-EML4-ALKv1/pMX-iresCD8 in which cDNA for EMLA-ALK fusion protein v1 was integrated,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144320(US8969336, 558 | US8969336, 582)copy SMILEScopy InChI
Affinity DataIC50: 0.370nMAssay Description:A partial protein of only a kinase domain of FLT3 protein was purchased from Carna Biosciences Inc., Japan, and tests were conducted as in Test Examp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144329(US8969336, 573)copy SMILEScopy InChI
Affinity DataIC50: 0.370nMAssay Description:A partial protein of only a kinase domain of FLT3 protein was purchased from Carna Biosciences Inc., Japan, and tests were conducted as in Test Examp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144328(US8969336, 572)copy SMILEScopy InChI
Affinity DataIC50: 0.370nMAssay Description:A partial protein of only a kinase domain of ROS protein was purchased from Carna Biosciences Inc., Japan, and tests were conducted as in Test Exampl...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144327(US8969336, 571)copy SMILEScopy InChI
Affinity DataIC50: 0.390nMAssay Description:A partial protein of only a kinase domain of FLT3 protein was purchased from Carna Biosciences Inc., Japan, and tests were conducted as in Test Examp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144321(US8969336, 565)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:A partial protein of only a kinase domain of ROS protein was purchased from Carna Biosciences Inc., Japan, and tests were conducted as in Test Exampl...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144319(US8969336, 554 | US8969336, 581)copy SMILEScopy InChI
Affinity DataIC50: 0.410nMAssay Description:A partial protein of only a kinase domain of ROS protein was purchased from Carna Biosciences Inc., Japan, and tests were conducted as in Test Exampl...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144315(Gilteritinib | US11512074, Example T-9 | US8969336...)copy SMILEScopy InChI
Affinity DataIC50: 0.410nMAssay Description:A partial protein of only a kinase domain of FLT3 protein was purchased from Carna Biosciences Inc., Japan, and tests were conducted as in Test Examp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144321(US8969336, 565)copy SMILEScopy InChI
Affinity DataIC50: 0.440nMAssay Description:A partial protein of only a kinase domain of FLT3 protein was purchased from Carna Biosciences Inc., Japan, and tests were conducted as in Test Examp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144323(US8969336, 567)copy SMILEScopy InChI
Affinity DataIC50: 0.460nMAssay Description:A partial protein of only a kinase domain of FLT3 protein was purchased from Carna Biosciences Inc., Japan, and tests were conducted as in Test Examp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50593531(ASP-5878 | ASP5878 | Asp 5878 | Asp-5878 | Asp5878)copy SMILES
Affinity DataIC50: 0.470nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79GDBPubMed
TargetTyrosine-protein kinase receptor(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144302(US8969336, 426)copy SMILEScopy InChI
Affinity DataIC50: 0.490nMAssay Description:A recombinant retrovirus was created from expression plasmid FLAG-EML4-ALKv1/pMX-iresCD8 in which cDNA for EMLA-ALK fusion protein v1 was integrated,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144318(US8969336, 553 | US8969336, 580)copy SMILEScopy InChI
Affinity DataIC50: 0.490nMAssay Description:A partial protein of only a kinase domain of FLT3 protein was purchased from Carna Biosciences Inc., Japan, and tests were conducted as in Test Examp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144324(US8969336, 568)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:A partial protein of only a kinase domain of FLT3 protein was purchased from Carna Biosciences Inc., Japan, and tests were conducted as in Test Examp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144326(US8969336, 570)copy SMILEScopy InChI
Affinity DataIC50: 0.510nMAssay Description:A partial protein of only a kinase domain of ROS protein was purchased from Carna Biosciences Inc., Japan, and tests were conducted as in Test Exampl...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144314(US8969336, 546 | US8969336, 576)copy SMILEScopy InChI
Affinity DataIC50: 0.510nMAssay Description:A partial protein of only a kinase domain of FLT3 protein was purchased from Carna Biosciences Inc., Japan, and tests were conducted as in Test Examp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144316(US8969336, 549 | US8969336, 578)copy SMILEScopy InChI
Affinity DataIC50: 0.510nMAssay Description:A partial protein of only a kinase domain of ROS protein was purchased from Carna Biosciences Inc., Japan, and tests were conducted as in Test Exampl...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144322(US8969336, 566)copy SMILEScopy InChI
Affinity DataIC50: 0.510nMAssay Description:A partial protein of only a kinase domain of FLT3 protein was purchased from Carna Biosciences Inc., Japan, and tests were conducted as in Test Examp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144319(US8969336, 554 | US8969336, 581)copy SMILEScopy InChI
Affinity DataIC50: 0.520nMAssay Description:A partial protein of only a kinase domain of FLT3 protein was purchased from Carna Biosciences Inc., Japan, and tests were conducted as in Test Examp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144316(US8969336, 549 | US8969336, 578)copy SMILEScopy InChI
Affinity DataIC50: 0.560nMAssay Description:A partial protein of only a kinase domain of FLT3 protein was purchased from Carna Biosciences Inc., Japan, and tests were conducted as in Test Examp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144317(US8969336, 550 | US8969336, 579)copy SMILEScopy InChI
Affinity DataIC50: 0.580nMAssay Description:A partial protein of only a kinase domain of ROS protein was purchased from Carna Biosciences Inc., Japan, and tests were conducted as in Test Exampl...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM50593531(ASP-5878 | ASP5878 | Asp 5878 | Asp-5878 | Asp5878)copy SMILES
Affinity DataIC50: 0.600nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79GDBPubMed
TargetTyrosine-protein kinase receptor(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144292(US8969336, 370)copy SMILEScopy InChI
Affinity DataIC50: 0.650nMAssay Description:A recombinant retrovirus was created from expression plasmid FLAG-EML4-ALKv1/pMX-iresCD8 in which cDNA for EMLA-ALK fusion protein v1 was integrated,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144325(US8969336, 569)copy SMILEScopy InChI
Affinity DataIC50: 0.650nMAssay Description:A partial protein of only a kinase domain of ROS protein was purchased from Carna Biosciences Inc., Japan, and tests were conducted as in Test Exampl...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144326(US8969336, 570)copy SMILEScopy InChI
Affinity DataIC50: 0.660nMAssay Description:A partial protein of only a kinase domain of FLT3 protein was purchased from Carna Biosciences Inc., Japan, and tests were conducted as in Test Examp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144331(US8969336, 575)copy SMILEScopy InChI
Affinity DataIC50: 0.720nMAssay Description:A partial protein of only a kinase domain of FLT3 protein was purchased from Carna Biosciences Inc., Japan, and tests were conducted as in Test Examp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetTyrosine-protein kinase receptor(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144289(US8969336, 354)copy SMILEScopy InChI
Affinity DataIC50: 0.770nMAssay Description:A recombinant retrovirus was created from expression plasmid FLAG-EML4-ALKv1/pMX-iresCD8 in which cDNA for EMLA-ALK fusion protein v1 was integrated,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144329(US8969336, 573)copy SMILEScopy InChI
Affinity DataIC50: 0.780nMAssay Description:A partial protein of only a kinase domain of ROS protein was purchased from Carna Biosciences Inc., Japan, and tests were conducted as in Test Exampl...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144327(US8969336, 571)copy SMILEScopy InChI
Affinity DataIC50: 0.860nMAssay Description:A partial protein of only a kinase domain of ROS protein was purchased from Carna Biosciences Inc., Japan, and tests were conducted as in Test Exampl...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144322(US8969336, 566)copy SMILEScopy InChI
Affinity DataIC50: 0.860nMAssay Description:A partial protein of only a kinase domain of ROS protein was purchased from Carna Biosciences Inc., Japan, and tests were conducted as in Test Exampl...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetTyrosine-protein kinase receptor(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144304(US8969336, 466)copy SMILEScopy InChI
Affinity DataIC50: 0.930nMAssay Description:A recombinant retrovirus was created from expression plasmid FLAG-EML4-ALKv1/pMX-iresCD8 in which cDNA for EMLA-ALK fusion protein v1 was integrated,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetTyrosine-protein kinase receptor(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144300(US8969336, 399)copy SMILEScopy InChI
Affinity DataIC50: 0.940nMAssay Description:A recombinant retrovirus was created from expression plasmid FLAG-EML4-ALKv1/pMX-iresCD8 in which cDNA for EMLA-ALK fusion protein v1 was integrated,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144322(US8969336, 566)copy SMILEScopy InChI
Affinity DataIC50: 0.950nMAssay Description:A partial protein of only a kinase domain of RET protein was purchased from Carna Biosciences Inc., Japan. The phosphorylation activity toward a pept...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
TargetTyrosine-protein kinase receptor(Homo sapiens (Human))
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM144281(US8969336, 110)copy SMILEScopy InChI
Affinity DataIC50: 0.990nMAssay Description:A recombinant retrovirus was created from expression plasmid FLAG-EML4-ALKv1/pMX-iresCD8 in which cDNA for EMLA-ALK fusion protein v1 was integrated,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9GZWUS Patent
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