Compile Data Set for Download or QSAR
Found 134 with Last Name = 'kaupmann' and Initial = 'k'
TargetGamma-aminobutyric acid type B receptor subunit 1(Rattus norvegicus (Rat))
Novartis Pharma AG

Curated by PDSP Ki Database
LigandPNGBDBM86283(CAS_345-78-8 | CAS_39069-52-8 | GS 39783 | N,N'...)copy SMILEScopy InChI
Affinity DataKi:  2.75nMMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1(Rattus norvegicus (Rat))
Novartis Pharma AG

Curated by PDSP Ki Database
LigandPNGBDBM86283(CAS_345-78-8 | CAS_39069-52-8 | GS 39783 | N,N'...)copy SMILEScopy InChI
Affinity DataKi:  32.4nMMore data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281849(CHEMBL4175305)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inverse agonist activity at human His6-tagged RORgammat LBD (264 to 518 residues) assessed as reduction in biotinylated RIP140 co-activator recruitme...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50337263(3-(2-chlorobenzyloxy)-2-(2-fluorophenyl)-2H-pyrazo...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]flumazenil from GABAA receptor subunit alpha-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q289164VPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM84957(CGS 9896 | CHEMBL20042)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]flumazenil from GABAA receptor subunit alpha-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q289164VPubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506051(CHEMBL4587988)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Displacement of RIP140 cofactor peptide from human His6-tagged RORgammat LBD (264 to 518 residues) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9TD7PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50337263(3-(2-chlorobenzyloxy)-2-(2-fluorophenyl)-2H-pyrazo...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]flumazenil from GABAA receptor subunit alpha-2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q289164VPubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281897(CHEMBL4171857)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Inverse agonist activity at human His6-tagged RORgammat LBD (264 to 518 residues) assessed as reduction in biotinylated RIP140 co-activator recruitme...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60RK3PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506053(CHEMBL4562740)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Displacement of RIP140 cofactor peptide from human His6-tagged RORgammat LBD (264 to 518 residues) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9TD7PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506050(CHEMBL4580481)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Displacement of RIP140 cofactor peptide from human His6-tagged RORgammat LBD (264 to 518 residues) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9TD7PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM84957(CGS 9896 | CHEMBL20042)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]flumazenil from GABAA receptor subunit alpha-2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q289164VPubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506052(CHEMBL4446191)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Displacement of RIP140 cofactor peptide from human His6-tagged RORgammat LBD (264 to 518 residues) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9TD7PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506049(CHEMBL4466072)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Displacement of RIP140 cofactor peptide from human His6-tagged RORgammat LBD (264 to 518 residues) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9TD7PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506056(CHEMBL4554462)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Displacement of RIP140 cofactor peptide from human His6-tagged RORgammat LBD (264 to 518 residues) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506048(CHEMBL4513808)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Displacement of RIP140 cofactor peptide from human His6-tagged RORgammat LBD (264 to 518 residues) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9TD7PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506057(CHEMBL4444848)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Displacement of RIP140 cofactor peptide from human His6-tagged RORgammat LBD (264 to 518 residues) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9TD7PubMed
TargetComplement factor D(Homo sapiens (Human))TBA
LigandPNGBDBM50524338(CHEMBL4468000)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human CFD expressed in Escherichia coli incubated up to 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2D8SPubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281849(CHEMBL4175305)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inverse agonist activity at human full-length eGFP-tagged RORgammat expressed in human HUT78 T-cells assessed as inhibition of PMA/CD3 monoclonal ant...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506050(CHEMBL4580481)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of human full-length eGFP-tagged RORgammat expressed in human HUT78 T-cells assessed as inhibition of PMA/CD3 monoclonal antibody stimulat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9TD7PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281849(CHEMBL4175305)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inverse agonist activity at human GAL4-DBD fused RORgammat LBD expressed in human Jurkat cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281985(CHEMBL4163551)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inverse agonist activity at human His6-tagged RORgammat LBD (264 to 518 residues) assessed as reduction in biotinylated RIP140 co-activator recruitme...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60RK3PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506049(CHEMBL4466072)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of human full-length eGFP-tagged RORgammat expressed in human HUT78 T-cells assessed as inhibition of PMA/CD3 monoclonal antibody stimulat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9TD7PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506047(CHEMBL4551475)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Displacement of RIP140 cofactor peptide from human His6-tagged RORgammat LBD (264 to 518 residues) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9TD7PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506046(CHEMBL4549748)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Displacement of RIP140 cofactor peptide from human His6-tagged RORgammat LBD (264 to 518 residues) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506051(CHEMBL4587988)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of human full-length eGFP-tagged RORgammat expressed in human HUT78 T-cells assessed as inhibition of PMA/CD3 monoclonal antibody stimulat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9TD7PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281849(CHEMBL4175305)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inverse agonist activity at RORgammat in human PBMC-derived CD4-positive Th-17 polarized cells assessed as reduction in IL4/anti-IFN-gamma antibody-s...More data for this Ligand-Target Pair
TargetSuccinate receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50561194(CHEMBL4790324)copy SMILES
Affinity DataIC50: 25nMAssay Description:Antagonist activity at human SUCNR1 expressed in human CHEM1 cells incubated for 60 mins in presence of [35S]GTPgammaS by scintillation proximity ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2D8SPubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281898(CHEMBL4164670)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inverse agonist activity at human His6-tagged RORgammat LBD (264 to 518 residues) assessed as reduction in biotinylated RIP140 co-activator recruitme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60RK3PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506054(CHEMBL4440185)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Displacement of RIP140 cofactor peptide from human His6-tagged RORgammat LBD (264 to 518 residues) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506052(CHEMBL4446191)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of human full-length eGFP-tagged RORgammat expressed in human HUT78 T-cells assessed as inhibition of PMA/CD3 monoclonal antibody stimulat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9TD7PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50337265(3-(2-chlorobenzyloxy)-2-(4-chlorophenyl)-6,7,8,9-t...)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Displacement of [3H]flumazenil from GABAA receptor subunit alpha-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q289164VPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50337264(2-(benzo[d][1,3]dioxol-5-yl)-3-(2-chlorobenzyloxy)...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Displacement of [3H]flumazenil from GABAA receptor subunit alpha-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q289164VPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50337271(2-(4-chlorophenyl)-3-(4-fluorobenzyloxy)-6,7,8,9-t...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Displacement of [3H]flumazenil from GABAA receptor subunit alpha-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q289164VPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50337271(2-(4-chlorophenyl)-3-(4-fluorobenzyloxy)-6,7,8,9-t...)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Displacement of [3H]flumazenil from GABAA receptor subunit alpha-2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q289164VPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50337270(2-(4-chlorophenyl)-3-(2-fluorobenzyloxy)-6,7,8,9-t...)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Displacement of [3H]flumazenil from GABAA receptor subunit alpha-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q289164VPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50337274(3-(2-chlorobenzyloxy)-2-(4-chlorophenyl)-2H-pyrazo...)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Displacement of [3H]flumazenil from GABAA receptor subunit alpha-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q289164VPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50337268(3-(2-chlorobenzyloxy)-2-(4-chlorophenyl)-8,8-dimet...)copy SMILEScopy InChI
Affinity DataIC50: 67nMAssay Description:Displacement of [3H]flumazenil from GABAA receptor subunit alpha-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q289164VPubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506048(CHEMBL4513808)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of human full-length eGFP-tagged RORgammat expressed in human HUT78 T-cells assessed as inhibition of PMA/CD3 monoclonal antibody stimulat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9TD7PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50337272(2-(4-chlorophenyl)-3-(cyclopropylmethoxy)-2H-pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 74nMAssay Description:Displacement of [3H]flumazenil from GABAA receptor subunit alpha-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q289164VPubMed
TargetSuccinate receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50561202(CHEMBL4763307)copy SMILES
Affinity DataIC50: 76nMAssay Description:Antagonist activity at human SUCNR1 expressed in human CHEM1 cells incubated for 60 mins in presence of [35S]GTPgammaS by scintillation proximity ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2D8SPubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506056(CHEMBL4554462)copy SMILEScopy InChI
Affinity DataIC50: 84nMAssay Description:Inhibition of human full-length eGFP-tagged RORgammat expressed in human HUT78 T-cells assessed as inhibition of PMA/CD3 monoclonal antibody stimulat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetSuccinate receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50561205(CHEMBL4751488)copy SMILES
Affinity DataIC50: 88nMAssay Description:Antagonist activity at human SUCNR1 expressed in human CHEM1 cells incubated for 60 mins in presence of [35S]GTPgammaS by scintillation proximity ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2D8SPubMed
TargetSuccinate receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50561204(CHEMBL4757124)copy SMILES
Affinity DataIC50: 90nMAssay Description:Antagonist activity at human SUCNR1 expressed in human CHEM1 cells incubated for 60 mins in presence of [35S]GTPgammaS by scintillation proximity ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2D8SPubMed
TargetSuccinate receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50561203(CHEMBL4752851)copy SMILES
Affinity DataIC50: 92nMAssay Description:Antagonist activity at human SUCNR1 expressed in human CHEM1 cells incubated for 60 mins in presence of [35S]GTPgammaS by scintillation proximity ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2D8SPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50337275(2-(4-chlorophenyl)-3-(cyclopropylmethoxy)-6,7,8,9-...)copy SMILEScopy InChI
Affinity DataIC50: 94nMAssay Description:Displacement of [3H]flumazenil from GABAA receptor subunit alpha-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q289164VPubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506055(CHEMBL4582076)copy SMILEScopy InChI
Affinity DataIC50: 105nMAssay Description:Displacement of RIP140 cofactor peptide from human His6-tagged RORgammat LBD (264 to 518 residues) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9TD7PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506057(CHEMBL4444848)copy SMILEScopy InChI
Affinity DataIC50: 111nMAssay Description:Inhibition of human full-length eGFP-tagged RORgammat expressed in human HUT78 T-cells assessed as inhibition of PMA/CD3 monoclonal antibody stimulat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9TD7PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506057(CHEMBL4444848)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of human GAL4-DBD fused RORgammat LBD expressed in human Jurkat cells assessed as inhibition of receptor transactivation after 24 hrs by l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9TD7PubMed
TargetComplement factor D(Homo sapiens (Human))TBA
LigandPNGBDBM50524345(CHEMBL4475961)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant human CFD expressed in Escherichia coli incubated up to 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506049(CHEMBL4466072)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of human GAL4-DBD fused RORgammat LBD expressed in human Jurkat cells assessed as inhibition of receptor transactivation after 24 hrs by l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9TD7PubMed
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