Compile Data Set for Download or QSAR
Found 84 with Last Name = 'kolinsky' and Initial = 'k'
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50426474(CHEMBL1980391)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2902541PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328264(5-(2-chlorophenyl)-3-isopropyl-7-nitro-2,10-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Hoffmann-La Roche, Inc.

Curated by ChEMBL
LigandPNGBDBM50365219(CHEMBL1956073)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of MEK1 in human HT-29 cells assessed as inhibition of ERK phosphorylation by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930TNWPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50363958(CHEMBL1952211)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant EE-tagged intracellular domain of KDR using biotin-EEEEYFELVAKKKK as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RWSPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328256(5-(2-fluorophenyl)-2,10-dihydrobenzo[e]pyrazolo[4,...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328279(5-(2-fluorophenyl)-2,10-dihydrobenzo[e]pyrazolo[4,...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328267(5-(2-chlorophenyl)-7-nitro-3-(1H-pyrrol-2-yl)-2,10...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Hoffmann-La Roche, Inc.

Curated by ChEMBL
LigandPNGBDBM50365219(CHEMBL1956073)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of MEK1 in human LOX cells assessed as inhibition of ERK phosphorylation by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930TNWPubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50426474(CHEMBL1980391)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of CHK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2902541PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328280(CHEMBL1258022 | N-(5-(2-chlorophenyl)-2,10-dihydro...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Hoffmann-La Roche, Inc.

Curated by ChEMBL
LigandPNGBDBM50365219(CHEMBL1956073)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of MEK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930TNWPubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50426474(CHEMBL1980391)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2902541PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328258(CHEMBL1257912 | N-(5-(2-chlorophenyl)-2,10-dihydro...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50426473(CHEMBL2322701)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2902541PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328257(5-(2-chlorophenyl)-2,10-dihydrobenzo[e]pyrazolo[4,...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328255(5-(2-chlorophenyl)-3-methyl-7-nitro-2,10-dihydrobe...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328258(CHEMBL1257912 | N-(5-(2-chlorophenyl)-2,10-dihydro...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328256(5-(2-fluorophenyl)-2,10-dihydrobenzo[e]pyrazolo[4,...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328274(7-fluoro-5-(2-fluorophenyl)-3-methyl-2,10-dihydrob...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50363957(CHEMBL1952210)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of human recombinant EE-tagged intracellular domain of KDR using biotin-EEEEYFELVAKKKK as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RWSPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50363957(CHEMBL1952210)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of human recombinant EE-tagged intracellular domain of KDR using biotin-EEEEYFELVAKKKK as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RWSPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328281(CHEMBL1258141 | N'-[5-(2-chlorophenyl)-2,10-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328269(5-(2-chlorophenyl)-7-nitro-3-(pyridin-4-yl)-2,10-d...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50426473(CHEMBL2322701)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2902541PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50182212(7-(4-fluorophenylamino)-1-((1S,3R)-3-hydroxycyclop...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against recombinant human KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46SRSPubMed
TargetAurora kinase A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50426474(CHEMBL1980391)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Inhibition of aurora-A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2902541PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328272(5-(2-fluorophenyl)-3-methyl-2,10-dihydrobenzo[e]py...)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Hoffmann-La Roche, Inc.

Curated by ChEMBL
LigandPNGBDBM50365219(CHEMBL1956073)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:Inhibition of MEK1 in human MIA PaCa-2 cells assessed as inhibition of ERK phosphorylation by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930TNWPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328260(5-(2-chlorophenyl)-7-nitro-2,10-dihydrobenzo[e]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328255(5-(2-chlorophenyl)-3-methyl-7-nitro-2,10-dihydrobe...)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Hoffmann-La Roche, Inc.

Curated by ChEMBL
LigandPNGBDBM50365219(CHEMBL1956073)copy SMILEScopy InChI
Affinity DataIC50: 82nMAssay Description:Inhibition of MEK1 in human H460 cells assessed as inhibition of ERK phosphorylation by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930TNWPubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50182212(7-(4-fluorophenylamino)-1-((1S,3R)-3-hydroxycyclop...)copy SMILEScopy InChI
Affinity DataIC50: 83nMAssay Description:Inhibitory activity against recombinant human PDGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46SRSPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328257(5-(2-chlorophenyl)-2,10-dihydrobenzo[e]pyrazolo[4,...)copy SMILEScopy InChI
Affinity DataIC50: 88nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50426473(CHEMBL2322701)copy SMILEScopy InChI
Affinity DataIC50: 88nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2902541PubMed
TargetFibroblast growth factor receptor 1/2/3/4(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50182212(7-(4-fluorophenylamino)-1-((1S,3R)-3-hydroxycyclop...)copy SMILEScopy InChI
Affinity DataIC50: 92nMAssay Description:Inhibitory activity against recombinant human FGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46SRSPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328273(7-fluoro-3-methyl-5-phenyl-2,10-dihydrobenzo[e]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 93nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328271(5-(2-chlorophenyl)-3-methyl-2,10-dihydrobenzo[e]py...)copy SMILEScopy InChI
Affinity DataIC50: 105nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328270(3-methyl-5-phenyl-2,10-dihydrobenzo[e]pyrazolo[4,3...)copy SMILEScopy InChI
Affinity DataIC50: 115nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328257(5-(2-chlorophenyl)-2,10-dihydrobenzo[e]pyrazolo[4,...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of FAKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328258(CHEMBL1257912 | N-(5-(2-chlorophenyl)-2,10-dihydro...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of FAKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328277(7-chloro-5-(2-fluorophenyl)-2,10-dihydrobenzo[e]py...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328265(5-(2-chlorophenyl)-7-nitro-3-phenyl-2,10-dihydrobe...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328262(5-(2-chlorophenyl)-7-nitro-3-(trifluoromethyl)-2,1...)copy SMILEScopy InChI
Affinity DataIC50: 232nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328261((5-(2-chlorophenyl)-7-nitro-2,10-dihydrobenzo[e]py...)copy SMILEScopy InChI
Affinity DataIC50: 238nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328263(5-(2-chlorophenyl)-7-nitro-2,10-dihydrobenzo[e]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 258nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328268(5-(2-chlorophenyl)-7-nitro-3-(pyridin-3-yl)-2,10-d...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50426473(CHEMBL2322701)copy SMILEScopy InChI
Affinity DataIC50: 303nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2902541PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50363957(CHEMBL1952210)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Inhibition of human recombinant His-tagged intracellular domain of EGFR using biotin-EEEEYFELV as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RWSPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50363957(CHEMBL1952210)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Inhibition of human recombinant His-tagged intracellular domain of EGFR using biotin-EEEEYFELV as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RWSPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328278(5-(2-chlorophenyl)-7-methoxy-2,10-dihydrobenzo[e]p...)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
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