Found 169 with Last Name = 'kuramochi' and Initial = 'k' TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Frontier Research Center for Genome & Drug Discovery
Curated by ChEMBL
Frontier Research Center for Genome & Drug Discovery
Curated by ChEMBL
Affinity DataKi: 3.75E+3nMAssay Description:Inhibition constant against DNA polymerase alpha non competitively on dNTP substrateMore data for this Ligand-Target Pair
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Frontier Research Center for Genome & Drug Discovery
Curated by ChEMBL
Frontier Research Center for Genome & Drug Discovery
Curated by ChEMBL
Affinity DataKi: 7.84E+3nMAssay Description:Inhibition constant against DNA polymerase alpha non competitively on dNTP substrateMore data for this Ligand-Target Pair
Affinity DataKi: 9.85E+3nMAssay Description:Competitive inhibition of human C-terminal-His6-tagged DNA polymerase kappa expressed in Escherichia coli using dTTP as substrate by Dixon plot analy...More data for this Ligand-Target Pair
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Frontier Research Center for Genome & Drug Discovery
Curated by ChEMBL
Frontier Research Center for Genome & Drug Discovery
Curated by ChEMBL
Affinity DataKi: 1.12E+4nMAssay Description:Inhibition constant against DNA polymerase alpha non competitively on dNTP substrateMore data for this Ligand-Target Pair
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Frontier Research Center for Genome & Drug Discovery
Curated by ChEMBL
Frontier Research Center for Genome & Drug Discovery
Curated by ChEMBL
Affinity DataKi: 1.38E+4nMAssay Description:Inhibition constant against DNA polymerase alpha competitively on DNA templateMore data for this Ligand-Target Pair
Affinity DataKi: 1.81E+4nMAssay Description:Non-competitive inhibition of human C-terminal-His6-tagged DNA polymerase kappa expressed in Escherichia coli using ploy(dA)/oligo(dT)18 as substrate...More data for this Ligand-Target Pair
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Frontier Research Center for Genome & Drug Discovery
Curated by ChEMBL
Frontier Research Center for Genome & Drug Discovery
Curated by ChEMBL
Affinity DataKi: 1.85E+4nMAssay Description:Inhibition constant against DNA polymerase alpha competitively on DNA templateMore data for this Ligand-Target Pair
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Frontier Research Center for Genome & Drug Discovery
Curated by ChEMBL
Frontier Research Center for Genome & Drug Discovery
Curated by ChEMBL
Affinity DataKi: 2.79E+4nMAssay Description:Inhibition constant against DNA polymerase alpha competitively on DNA templateMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
Affinity DataIC50: 90nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
Affinity DataIC50: 180nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
Affinity DataIC50: 240nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
Affinity DataIC50: 680nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
Affinity DataIC50: 890nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
TargetDNA nucleotidylexotransferase(Homo sapiens (Human))
Tokyo University of Science
Curated by ChEMBL
Tokyo University of Science
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibitory activity of the compound against human terminal deoxynucleotidyltransferaseMore data for this Ligand-Target Pair
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of C-terminal His6-tagged human DNA polymerase kappa (amino acids 1 to 560) using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA tem...More data for this Ligand-Target Pair
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of C-terminal His6-tagged human DNA polymerase eta (amino acids 1 to 511) using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA templ...More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of His-tagged human DNA polymerase lambda using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleotide substr...More data for this Ligand-Target Pair
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of C-terminal His6-tagged mouse DNA polymerase iota using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleot...More data for this Ligand-Target Pair
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of rat pol beta using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleotide substrate after 60 minsMore data for this Ligand-Target Pair
TargetDNA-directed DNA/RNA polymerase mu(Homo sapiens (Human))
Kyoto Prefectural University
Curated by ChEMBL
Kyoto Prefectural University
Curated by ChEMBL
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of His-tagged human DNA polymerase mu using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleotide substrate ...More data for this Ligand-Target Pair
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Frontier Research Center for Genome & Drug Discovery
Curated by ChEMBL
Frontier Research Center for Genome & Drug Discovery
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibitory concentration against human DNA polymerase alpha incubated with 0.05 unitsMore data for this Ligand-Target Pair
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of C-terminal His6-tagged human DNA polymerase kappa (amino acids 1 to 560) using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA tem...More data for this Ligand-Target Pair
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of C-terminal His6-tagged human DNA polymerase eta (amino acids 1 to 511) using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA templ...More data for this Ligand-Target Pair
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of calf thymus TdT using oligo(dT)18 (3'-OH) and dTTP as the DNA template-primer and nucleotide substrate after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of C-terminal His6-tagged mouse DNA polymerase iota using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleot...More data for this Ligand-Target Pair
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of His-tagged human DNA polymerase lambda using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleotide substr...More data for this Ligand-Target Pair
TargetDNA-directed DNA/RNA polymerase mu(Homo sapiens (Human))
Kyoto Prefectural University
Curated by ChEMBL
Kyoto Prefectural University
Curated by ChEMBL
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of His-tagged human DNA polymerase mu using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleotide substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory concentration against rat DNA polymerase beta incubated with 0.05 unitsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibition of rat pol beta using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleotide substrate after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.19E+4nMAssay Description:Inhibition of calf thymus TdT using oligo(dT)18 (3'-OH) and dTTP as the DNA template-primer and nucleotide substrate after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.19E+4nMAssay Description:Inhibition of rat DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA nucleotidylexotransferase(Homo sapiens (Human))
Tokyo University of Science
Curated by ChEMBL
Tokyo University of Science
Curated by ChEMBL
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibitory activity of the compound against human terminal deoxynucleotidyltransferaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of rat DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA nucleotidylexotransferase(Homo sapiens (Human))
Tokyo University of Science
Curated by ChEMBL
Tokyo University of Science
Curated by ChEMBL
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibitory activity of the compound against human terminal deoxynucleotidyltransferaseMore data for this Ligand-Target Pair
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Frontier Research Center for Genome & Drug Discovery
Curated by ChEMBL
Frontier Research Center for Genome & Drug Discovery
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory concentration against human DNA polymerase alpha incubated with 0.05 unitsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+4nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
Affinity DataIC50: 2.73E+4nMAssay Description:Inhibition of rat DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Frontier Research Center for Genome & Drug Discovery
Curated by ChEMBL
Frontier Research Center for Genome & Drug Discovery
Curated by ChEMBL
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibitory concentration against human DNA polymerase alpha incubated with 0.05 unitsMore data for this Ligand-Target Pair
TargetDNA polymerase subunit gamma-1(Homo sapiens (Human))
Tokyo University of Science
Curated by ChEMBL
Tokyo University of Science
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human DNA polymerase gammaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+4nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Frontier Research Center for Genome & Drug Discovery
Curated by ChEMBL
Frontier Research Center for Genome & Drug Discovery
Curated by ChEMBL
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibitory concentration against human DNA polymerase alpha incubated with 0.05 unitsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.86E+4nMAssay Description:Inhibition of human C-terminal-His6-tagged DNA polymerase kappa expressed in Escherichia coli assessed as inhibition of incorporation of dTTP into po...More data for this Ligand-Target Pair
Affinity DataIC50: 5.02E+4nMAssay Description:Inhibition of mouse recombinant C-terminal-His6-tagged DNA polymerase iota assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.09E+4nMAssay Description:Inhibition of C-terminal-His6-tagged human pol nu expressed in Escherichia coli assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(d...More data for this Ligand-Target Pair
TargetDNA polymerase delta catalytic subunit(Homo sapiens (Human))
Science University of Tokyo
Curated by ChEMBL
Science University of Tokyo
Curated by ChEMBL
Affinity DataIC50: 5.45E+4nMAssay Description:Inhibition of human DNA polymerase delta assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.98E+4nMAssay Description:Inhibition of human C-terminal-His6-tagged DNA polymerase kappa expressed in Escherichia coli assessed as inhibition of incorporation of dTTP into po...More data for this Ligand-Target Pair
Affinity DataIC50: 5.98E+4nMAssay Description:Inhibition of human DNA polymerase kappaMore data for this Ligand-Target Pair
Affinity DataIC50: 6.01E+4nMAssay Description:Inhibition of rat DNA polymerase betaMore data for this Ligand-Target Pair
