Compile Data Set for Download or QSAR
Found 216 with Last Name = 'nishikawa' and Initial = 'k'
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50406422(CHEMBL2115381)copy SMILEScopy InChI
Affinity DataIC50: 4.30nMAssay Description:Reduction of lipid peroxide formed in rat brain homogenates.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010968(3-(2,5-Dimethyl-3,6-dioxo-4-pyridin-3-ylmethyl-cyc...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026531(2,2-Dimethyl-7-pyridin-3-yl-7-thiophen-2-yl-hept-6...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZPBPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026538(7-Naphthalen-2-yl-7-pyridin-3-yl-hept-6-enoic acid...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZPBPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026481(7-Pyridin-3-yl-7-thiophen-2-yl-hept-6-enoic acid |...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZPBPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026507(2,2-Dimethyl-7-phenyl-7-pyridin-3-yl-hept-6-enoic ...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZPBPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50010960((E)-7-Phenyl-7-pyridin-3-yl-hept-6-enoic acid | 7-...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50010960((E)-7-Phenyl-7-pyridin-3-yl-hept-6-enoic acid | 7-...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZPBPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026497(2-Isopropenyl-7-phenyl-7-pyridin-3-yl-hept-6-enoic...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZPBPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026521(7-Phenyl-2-prop-2-ynyl-7-pyridin-3-yl-hept-6-enoic...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZPBPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026493(7-(3-Methyl-thiophen-2-yl)-7-pyridin-3-yl-hept-6-e...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZPBPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026508(8-Phenyl-8-pyridin-3-yl-oct-7-enoic acid | CHEMBL3...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZPBPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026549(2,2-Dimethyl-7-phenyl-7-pyridin-3-yl-hept-6-enoic ...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZPBPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026526(2-Methylsulfanyl-7-phenyl-7-pyridin-3-yl-hept-6-en...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZPBPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026519(6-Phenyl-6-pyridin-3-yl-hex-5-enoic acid | CHEMBL1...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZPBPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026490(7-Pyridin-3-yl-7-thiophen-3-yl-hept-6-enoic acid |...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZPBPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026503(10-Phenyl-10-pyridin-3-yl-dec-9-enoic acid | CHEMB...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZPBPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026499(2-Phenyl-7-pyridin-3-yl-7-thiophen-2-yl-hept-6-eno...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZPBPubMed
TargetType-1 angiotensin II receptor(Bos taurus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50044403(2-Methoxy-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylme...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20Z73X8PubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026528(7-Phenyl-2-phenylsulfanyl-7-pyridin-3-yl-hept-6-en...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZPBPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026546(7-Naphthalen-1-yl-7-pyridin-3-yl-hept-6-enoic acid...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZPBPubMed
TargetType-1 angiotensin II receptor(Bos taurus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50282377(2-Butyl-7-methyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Concentration required to inhibit [125I]-AII binding to Angiotensin II receptor from membrane fractions of bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z44CP
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026551(2,2-Dimethyl-7-pyridin-3-yl-7-thiophen-2-yl-hept-6...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZPBPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026537(2,2-Dimethyl-8-phenyl-8-pyridin-3-yl-oct-7-enoic a...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZPBPubMed
TargetType-1 angiotensin II receptor(Bos taurus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50044379(2-Propylamino-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20Z73X8PubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026501(2-Methoxymethyl-7-phenyl-7-pyridin-3-yl-hept-6-eno...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZPBPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026511(7-Benzo[1,3]dioxol-5-yl-7-pyridin-3-yl-hept-6-enoi...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZPBPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026542(9-Phenyl-9-pyridin-3-yl-non-8-enoic acid | CHEMBL9...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZPBPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026539(11-Phenyl-11-pyridin-3-yl-undec-10-enoic acid | CH...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZPBPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026532(2-(1-Hydroxy-1-methyl-ethyl)-7-phenyl-7-pyridin-3-...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZPBPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026496(2,2-Dimethyl-8-pyridin-3-yl-8-thiophen-2-yl-oct-7-...)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZPBPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50010949(8-Pyridin-3-yl-8-(2,4,5-trimethyl-3,6-dioxo-cycloh...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026552(2,2-Dimethyl-8-phenyl-8-pyridin-3-yl-oct-7-enoic a...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZPBPubMed
TargetType-1 angiotensin II receptor(Bos taurus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50044410(2-Ethyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmeth...)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20Z73X8PubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026548(2,2-Dimethyl-8-pyridin-3-yl-8-thiophen-2-yl-oct-7-...)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZPBPubMed
TargetType-1 angiotensin II receptor(Bos taurus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50282379(2-Propyl-1-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmet...)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Concentration required to inhibit [125I]-AII binding to Angiotensin II receptor from membrane fractions of bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z44CP
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026516(2-Phenyl-7-pyridin-3-yl-7-thiophen-2-yl-hept-6-eno...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZPBPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026487(2-Allyl-7-phenyl-7-pyridin-3-yl-hept-6-enoic acid ...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZPBPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026486((Z)-7-Phenyl-7-pyridin-3-yl-hept-6-enoic acid | 7-...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZPBPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026486((Z)-7-Phenyl-7-pyridin-3-yl-hept-6-enoic acid | 7-...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZPBPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026500(7-Pyridin-3-yl-7-(3-trifluoromethyl-phenyl)-hept-6...)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZPBPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026505((Z)-7-Pyridin-3-yl-7-thiophen-2-yl-hept-6-enoic ac...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZPBPubMed
TargetType-1 angiotensin II receptor(Bos taurus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50282373(2-Butyl-7-methyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Concentration required to inhibit [125I]-AII binding to Angiotensin II receptor from membrane fractions of bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z44CP
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026535(7-(3-Fluoro-phenyl)-7-pyridin-3-yl-hept-6-enoic ac...)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZPBPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026545(12-Phenyl-12-pyridin-3-yl-dodec-11-enoic acid | CH...)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZPBPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026484((Z)-7-Benzo[1,3]dioxol-5-yl-7-pyridin-3-yl-hept-6-...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZPBPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026524(2-Benzyl-7-phenyl-7-pyridin-3-yl-hept-6-enoic acid...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZPBPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026547(2-Cyclopent-1-enyl-7-phenyl-7-pyridin-3-yl-hept-6-...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZPBPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026517((Z)-7-Naphthalen-2-yl-7-pyridin-3-yl-hept-6-enoic ...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZPBPubMed
TargetType-1 angiotensin II receptor(Bos taurus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50044414(2-Ethylamino-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20Z73X8PubMed
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