Affinity DataKi: 1nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Hoffmann-La Roche Inc.
Affinity DataKi: 1nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Hoffmann-La Roche Inc.
Affinity DataKi: 5nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
Affinity DataKi: 8.40nMAssay Description:Binding affinity to wild-type androgen receptor in human LNCaP cells assessed as inhibition constant incubated for 24 hrs by Cheng-Prusoff equation a...More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Hoffmann-La Roche Inc.
Affinity DataKi: 14nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Hoffmann-La Roche Inc.
Affinity DataKi: 14nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Binding affinity to wild-type androgen receptor in human LNCaP cells assessed as inhibition constant incubated for 24 hrs by Cheng-Prusoff equation a...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Hoffmann-La Roche Inc.
Affinity DataKi: 17nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
Affinity DataKi: 24nM ΔG°: -45.2kJ/molepH: 7.0 T: 2°CAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Hoffmann-La Roche Inc.
Affinity DataKi: 28nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Hoffmann-La Roche Inc.
Affinity DataKi: 38nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Hoffmann-La Roche Inc.
Affinity DataKi: 43nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
Affinity DataKi: 51nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
Affinity DataKi: 66nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
Affinity DataKi: 84nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
Affinity DataKi: 98nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Hoffmann-La Roche Inc.
Affinity DataKi: 133nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
Affinity DataKi: 159nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Hoffmann-La Roche Inc.
Affinity DataKi: 181nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Hoffmann-La Roche Inc.
Affinity DataKi: 193nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Hoffmann-La Roche Inc.
Affinity DataKi: 246nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
Affinity DataKi: 267nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Hoffmann-La Roche Inc.
Affinity DataKi: 278nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
Affinity DataKi: 327nM ΔG°: -38.5kJ/molepH: 7.0 T: 2°CAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
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