Compile Data Set for Download or QSAR
Found 334 with Last Name = 'peng' and Initial = 'k'
TargetKappa-type opioid receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50264567(CHEMBL4063074)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:Displacement of [3H]-U69593 from human kappa opiod receptor expressed in CHO cells incubated for 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82DVQPubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50264567(CHEMBL4063074)copy SMILEScopy InChI
Affinity DataKi:  94nMAssay Description:Displacement of [3H]-DAMGO from human mu opiod receptor expressed in CHO cells incubated for 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82DVQPubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50264567(CHEMBL4063074)copy SMILEScopy InChI
Affinity DataKi:  105nMAssay Description:Displacement of [3H]-DPDPE from human delta opiod receptor expressed in human HEK293 cells incubated for 60 mins by liquid scintillation counting met...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82DVQPubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50542605(CHEMBL4648915)copy SMILEScopy InChI
Affinity DataKi:  180nMAssay Description:Displacement of [3H]-U69593 from human kappa opiod receptor expressed in CHO cells incubated for 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82DVQPubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50542606(CHEMBL4636535)copy SMILEScopy InChI
Affinity DataKi:  498nMAssay Description:Displacement of [3H]-U69593 from human kappa opiod receptor expressed in CHO cells incubated for 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82DVQPubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50542608(CHEMBL4638966)copy SMILEScopy InChI
Affinity DataKi:  1.41E+3nMAssay Description:Displacement of [3H]-U69593 from human kappa opiod receptor expressed in CHO cells incubated for 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82DVQPubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50542608(CHEMBL4638966)copy SMILEScopy InChI
Affinity DataKi:  1.48E+3nMAssay Description:Displacement of [3H]-DAMGO from human mu opiod receptor expressed in CHO cells incubated for 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82DVQPubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50542607(CHEMBL4644052)copy SMILEScopy InChI
Affinity DataKi:  2.15E+3nMAssay Description:Displacement of [3H]-U69593 from human kappa opiod receptor expressed in CHO cells incubated for 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82DVQPubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50542605(CHEMBL4648915)copy SMILEScopy InChI
Affinity DataKi:  2.31E+3nMAssay Description:Displacement of [3H]-DAMGO from human mu opiod receptor expressed in CHO cells incubated for 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82DVQPubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50542606(CHEMBL4636535)copy SMILEScopy InChI
Affinity DataKi:  2.80E+3nMAssay Description:Displacement of [3H]-DAMGO from human mu opiod receptor expressed in CHO cells incubated for 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82DVQPubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50542607(CHEMBL4644052)copy SMILEScopy InChI
Affinity DataKi:  4.76E+3nMAssay Description:Displacement of [3H]-DAMGO from human mu opiod receptor expressed in CHO cells incubated for 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82DVQPubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50542608(CHEMBL4638966)copy SMILEScopy InChI
Affinity DataKi:  5.01E+3nMAssay Description:Displacement of [3H]-DPDPE from human delta opiod receptor expressed in human HEK293 cells incubated for 60 mins by liquid scintillation counting met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82DVQPubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50542605(CHEMBL4648915)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-DPDPE from human delta opiod receptor expressed in human HEK293 cells incubated for 60 mins by liquid scintillation counting met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82DVQPubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50542606(CHEMBL4636535)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-DPDPE from human delta opiod receptor expressed in human HEK293 cells incubated for 60 mins by liquid scintillation counting met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82DVQPubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50542607(CHEMBL4644052)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-DPDPE from human delta opiod receptor expressed in human HEK293 cells incubated for 60 mins by liquid scintillation counting met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82DVQPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50303246((1S,3'R,4'S,5'S,6'R)-5-chloro-6'-(hydroxymethyl)-6...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human SGLT2 transfected in HEK293.ETN cells assessed as AMG uptake after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC903RPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321299((2S,3R,4R,5S,6R)-2-(4-chloro-5-(4-ethylbenzyl)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside uptake after 1.5 hrs by liquid sci...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7B8NPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50520035(CHEMBL4461392)copy SMILEScopy InChI
Affinity DataIC50: 0.437nMAssay Description:Inhibition of recombinant human PARP1 using histone as substrate after 1 hr in presence of biotinylated NAD+ by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QPDPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50520036(CHEMBL4437593)copy SMILEScopy InChI
Affinity DataIC50: 0.646nMAssay Description:Inhibition of recombinant human PARP1 using histone as substrate after 1 hr in presence of biotinylated NAD+ by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QPDPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50520043(CHEMBL4549595)copy SMILEScopy InChI
Affinity DataIC50: 0.676nMAssay Description:Inhibition of recombinant human PARP1 using histone as substrate after 1 hr in presence of biotinylated NAD+ by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QPDPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50520026(CHEMBL4525998)copy SMILEScopy InChI
Affinity DataIC50: 0.692nMAssay Description:Inhibition of recombinant human PARP1 using histone as substrate after 1 hr in presence of biotinylated NAD+ by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QPDPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50520031(CHEMBL4436980)copy SMILEScopy InChI
Affinity DataIC50: 0.724nMAssay Description:Inhibition of recombinant human PARP1 using histone as substrate after 1 hr in presence of biotinylated NAD+ by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QPDPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50308469((2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-methoxybenzyl)ph...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of full length human SGLT2 assessed as methyl-alpha-D-[U-14C]glucopyranoside uptake after 1.5 hrs by cell-based topcount scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50PF5PubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50303254((1S,3'R,4'S,5'S,6'R)-5-chloro-6-(2-fluoro-3-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human SGLT2 transfected in HEK293.ETN cells assessed as AMG uptake after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC903RPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50520042(CHEMBL4571423)copy SMILEScopy InChI
Affinity DataIC50: 0.832nMAssay Description:Inhibition of recombinant human PARP1 using histone as substrate after 1 hr in presence of biotinylated NAD+ by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QPDPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50520033(CHEMBL4461382)copy SMILEScopy InChI
Affinity DataIC50: 0.832nMAssay Description:Inhibition of recombinant human PARP1 using histone as substrate after 1 hr in presence of biotinylated NAD+ by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QPDPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321288((2S,3R,4R,5S,6R)-2-(4-chloro-5-(4-ethylbenzyl)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside uptake after 1.5 hrs by liquid sci...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7B8NPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321300((2S,3R,4R,5S,6R)-2-(4-chloro-5-(4-ethoxybenzyl)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside uptake after 1.5 hrs by liquid sci...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7B8NPubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM418817(N-methyl-4-({4-[({3- [methyl(methylsulfonyl)amino]...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human Focal adhesion kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5K8CPubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human PARP2 using histone as substrate after 1 hr in presence of biotinylated NAD+ by ELISAMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50520030(CHEMBL4436366)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant human PARP1 using histone as substrate after 1 hr in presence of biotinylated NAD+ by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QPDPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50520032(CHEMBL4551779)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant human PARP1 using histone as substrate after 1 hr in presence of biotinylated NAD+ by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QPDPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50520041(CHEMBL4446789)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant human PARP1 using histone as substrate after 1 hr in presence of biotinylated NAD+ by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QPDPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50520027(CHEMBL4438927)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant human PARP1 using histone as substrate after 1 hr in presence of biotinylated NAD+ by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QPDPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321290((2S,3R,4R,5S,6R)-2-(4-chloro-5-(4-ethylbenzyl)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside uptake after 1.5 hrs by liquid sci...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7B8NPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50303239((1S,3'R,4'S,5'S,6'R)-5-chloro-4-(1-(4-ethylphenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human SGLT2 transfected in HEK293.ETN cells assessed as AMG uptake after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC903RPubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM418817(N-methyl-4-({4-[({3- [methyl(methylsulfonyl)amino]...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of GST-FAK catalytic domain region (411-686) (unknown origin) expressed in baculovirus infected Sf9 cells by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5K8CPubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50440659(CHEMBL2430358)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of GST-FAK catalytic domain region (411-686) (unknown origin) expressed in baculovirus infected Sf9 cells by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5K8CPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321292((2S,3R,4R,5S,6R)-2-(4-chloro-5-(4-ethylbenzyl)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside uptake after 1.5 hrs by liquid sci...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7B8NPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50285416(CHEMBL4161733)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human IDO1More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50349240(CHEMBL1807551)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human SGLT2 expressed in african green monkey COS7 cells assessed as inhibition of [14C]-methyl-alpha-D-glucopyranoside uptake after 2 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0FVZPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50265139((2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-ethylbenzyl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside uptake after 1.5 hrs by liquid sci...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7B8NPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50308469((2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-methoxybenzyl)ph...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition of full length human SGLT2 assessed as methyl-alpha-D-[U-14C]glucopyranoside uptake after 1.5 hrs by cell-based topcount scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50PF5PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50587578(CHEMBL5091825)copy SMILES
Affinity DataIC50: 2.20nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells assessed as reduction in kynurenine formation measured after 48 hrs by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DJFPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50349249(CHEMBL1808388)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human SGLT2 expressed in african green monkey COS7 cells assessed as inhibition of [14C]-methyl-alpha-D-glucopyranoside uptake after 2 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0FVZPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50448923(CHEMBL3125316 | CHEMBL3125317 | CHEMBL3125318 | CH...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of full length human SGLT2 assessed as methyl-alpha-D-[U-14C]glucopyranoside uptake after 1.5 hrs by cell-based topcount scintillation cou...More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50308469((2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-methoxybenzyl)ph...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of full length human SGLT2 assessed as methyl-alpha-D-[U-14C]glucopyranoside uptake after 1.5 hrs by cell-based topcount scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50PF5PubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50303242((1S,3'R,4'S,5'S,6'R)-5-chloro-6'-(hydroxymethyl)-6...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human SGLT2 transfected in HEK293.ETN cells assessed as AMG uptake after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC903RPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50520040(CHEMBL4438741)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of recombinant human PARP1 using histone as substrate after 1 hr in presence of biotinylated NAD+ by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QPDPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50448923(CHEMBL3125316 | CHEMBL3125317 | CHEMBL3125318 | CH...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Inhibition of full length human SGLT2 assessed as methyl-alpha-D-[U-14C]glucopyranoside uptake after 1.5 hrs by cell-based topcount scintillation cou...More data for this Ligand-Target Pair
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