Compile Data Set for Download or QSAR
Found 136 with Last Name = 'sakaguchi' and Initial = 'k'
TargetProtein phosphatase 1D(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50118477(CHEMBL3613748)copy SMILEScopy InChI
Affinity DataKi:  228nMAssay Description:Non-competitive inhibition of His-tagged PPM1D (1 to 420 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) pLysS cells using Ac-VEP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26975C7PubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
Centre National de la Recherche Scientifique& Universite de Nantes

Curated by ChEMBL
LigandPNGBDBM50416570(CHEMBL1215819)copy SMILEScopy InChI
Affinity DataKi:  750nMAssay Description:Inhibition of human RAD51 assessed as concentration required for half dissociation of protein/single-stranded DNA complex formation by fluorescence p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4RV5PubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
Centre National de la Recherche Scientifique& Universite de Nantes

Curated by ChEMBL
LigandPNGBDBM50416568(CHEMBL1215817)copy SMILEScopy InChI
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of human RAD51 assessed as concentration required for half dissociation of protein/single-stranded DNA complex formation by fluorescence p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4RV5PubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Frontier Research Center for Genome & Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50153106(CHEMBL189703 | [(3S,10R,13R,17R)-17-((R)-1,5-Dimet...)copy SMILEScopy InChI
Affinity DataKi:  3.75E+3nMAssay Description:Inhibition constant against DNA polymerase alpha non competitively on dNTP substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN37BHPubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
Centre National de la Recherche Scientifique& Universite de Nantes

Curated by ChEMBL
LigandPNGBDBM50416569(CHEMBL1215818)copy SMILEScopy InChI
Affinity DataKi:  4.20E+3nMAssay Description:Inhibition of human RAD51 assessed as concentration required for half dissociation of protein/single-stranded DNA complex formation by fluorescence p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4RV5PubMed
TargetDNA polymerase beta(Rattus norvegicus)
Tokyo University of Science

Curated by ChEMBL
LigandPNGBDBM50109030(4-(3-Hydroxy-10,13-dimethyl-hexadecahydro-cyclopen...)copy SMILEScopy InChI
Affinity DataKi:  4.70E+3nMAssay Description:Inhibition constant of the compound was determined at a concentration of 5 microM on rat DNA polymerase beta as a function of template primer doseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936TCPubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
Centre National de la Recherche Scientifique& Universite de Nantes

Curated by ChEMBL
LigandPNGBDBM50416566(CHEMBL1215815)copy SMILEScopy InChI
Affinity DataKi:  6.00E+3nMAssay Description:Inhibition of human RAD51 assessed as concentration required for half dissociation of protein/single-stranded DNA complex formation by fluorescence p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4RV5PubMed
TargetDNA polymerase beta(Rattus norvegicus)
Tokyo University of Science

Curated by ChEMBL
LigandPNGBDBM50109030(4-(3-Hydroxy-10,13-dimethyl-hexadecahydro-cyclopen...)copy SMILEScopy InChI
Affinity DataKi:  6.60E+3nMAssay Description:Inhibition constant of the compound was determined at a concentration of 10 microM on rat DNA polymerase beta as a function of nucleotide substrate c...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936TCPubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Frontier Research Center for Genome & Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50153111(CHEMBL189667 | [(3S,5S,10S,13R,17R)-17-((R)-1,5-Di...)copy SMILEScopy InChI
Affinity DataKi:  7.84E+3nMAssay Description:Inhibition constant against DNA polymerase alpha non competitively on dNTP substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN37BHPubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
Centre National de la Recherche Scientifique& Universite de Nantes

Curated by ChEMBL
LigandPNGBDBM50416564(CHEMBL1215813)copy SMILEScopy InChI
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of human RAD51 assessed as concentration required for half dissociation of protein/single-stranded DNA complex formation by fluorescence p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4RV5PubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Frontier Research Center for Genome & Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50153113(CHEMBL364611 | [(3S,10R,13R,17R)-17-((E)-(1R,4S)-4...)copy SMILEScopy InChI
Affinity DataKi:  1.12E+4nMAssay Description:Inhibition constant against DNA polymerase alpha non competitively on dNTP substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN37BHPubMed
TargetDNA polymerase beta(Rattus norvegicus)
Tokyo University of Science

Curated by ChEMBL
LigandPNGBDBM50109029(4-{10,13-Dimethyl-3-[3-(6-{6-[5-(2-oxo-hexahydro-t...)copy SMILEScopy InChI
Affinity DataKi:  1.28E+4nMAssay Description:Inhibition constant of the compound was determined at a concentration of 5 microM on rat DNA polymerase beta as a function of template primer doseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936TCPubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Frontier Research Center for Genome & Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50153111(CHEMBL189667 | [(3S,5S,10S,13R,17R)-17-((R)-1,5-Di...)copy SMILEScopy InChI
Affinity DataKi:  1.38E+4nMAssay Description:Inhibition constant against DNA polymerase alpha competitively on DNA templateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN37BHPubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Frontier Research Center for Genome & Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50153106(CHEMBL189703 | [(3S,10R,13R,17R)-17-((R)-1,5-Dimet...)copy SMILEScopy InChI
Affinity DataKi:  1.85E+4nMAssay Description:Inhibition constant against DNA polymerase alpha competitively on DNA templateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN37BHPubMed
TargetDNA polymerase beta(Rattus norvegicus)
Tokyo University of Science

Curated by ChEMBL
LigandPNGBDBM50109029(4-{10,13-Dimethyl-3-[3-(6-{6-[5-(2-oxo-hexahydro-t...)copy SMILEScopy InChI
Affinity DataKi:  2.01E+4nMAssay Description:Inhibition constant of the compound was determined at a concentration of 10 microM on rat DNA polymerase beta as a function of template primer doseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936TCPubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Frontier Research Center for Genome & Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50153113(CHEMBL364611 | [(3S,10R,13R,17R)-17-((E)-(1R,4S)-4...)copy SMILEScopy InChI
Affinity DataKi:  2.79E+4nMAssay Description:Inhibition constant against DNA polymerase alpha competitively on DNA templateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN37BHPubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
Centre National de la Recherche Scientifique& Universite de Nantes

Curated by ChEMBL
LigandPNGBDBM50416567(CHEMBL1215816)copy SMILEScopy InChI
Affinity DataKi: >4.00E+4nMAssay Description:Inhibition of human RAD51 assessed as concentration required for half dissociation of protein/single-stranded DNA complex formation by fluorescence p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4RV5PubMed
TargetProtein phosphatase 1D(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50118478(CHEMBL3613749)copy SMILEScopy InChI
Affinity DataIC50: 86nMAssay Description:Inhibition of His-tagged PPM1D (1 to 420 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) pLysS cells using Ac-VEPPLS(P)QETFSDLW-N...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26975C7PubMed
TargetProtein phosphatase 1D(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50361941(CHEMBL1939361)copy SMILEScopy InChI
Affinity DataIC50: 87nMAssay Description:Inhibition of His-tagged PPM1D (1 to 420 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) pLysS cells using Ac-VEPPLS(P)QETFSDLW-N...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26975C7PubMed
TargetProtein phosphatase 1D(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50118477(CHEMBL3613748)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of His-tagged PPM1D (1 to 420 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) pLysS cells using Ac-VEPPLS(P)QETFSDLW-N...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26975C7PubMed
TargetProtein phosphatase 1D(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50118476(CHEMBL3613747)copy SMILEScopy InChI
Affinity DataIC50: 215nMAssay Description:Inhibition of His-tagged PPM1D (1 to 420 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) pLysS cells using Ac-VEPPLS(P)QETFSDLW-N...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26975C7PubMed
TargetHistone deacetylase(Homo sapiens (Human))
Saga University

Curated by ChEMBL
LigandPNGBDBM50481610(CHEMBL609609)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4ZMKPubMed
TargetHistone deacetylase(Homo sapiens (Human))
Saga University

Curated by ChEMBL
LigandPNGBDBM50481612(CHEMBL596660)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4ZMKPubMed
TargetHistone deacetylase(Homo sapiens (Human))
Saga University

Curated by ChEMBL
LigandPNGBDBM50481613(CHEMBL597443)copy SMILEScopy InChI
Affinity DataIC50: 360nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4ZMKPubMed
TargetProtein phosphatase 1D(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50361941(CHEMBL1939361)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Inhibition of N-terminal histidine-tagged PPM1Dc after 10 mins using BIOMOL GREEN assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N81KJPubMed
TargetHistone deacetylase(Homo sapiens (Human))
Saga University

Curated by ChEMBL
LigandPNGBDBM50481611(CHEMBL599968)copy SMILEScopy InChI
Affinity DataIC50: 510nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4ZMKPubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
Centre National de la Recherche Scientifique& Universite de Nantes

Curated by ChEMBL
LigandPNGBDBM50416570(CHEMBL1215819)copy SMILEScopy InChI
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of human RAD51 assessed as dissociation of protein/single-stranded oligo(AGT)12 complex formation by fluorescence polarimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4RV5PubMed
TargetHistone deacetylase(Homo sapiens (Human))
Saga University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract by fluorescence assayMore data for this Ligand-Target Pair
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
Centre National de la Recherche Scientifique& Universite de Nantes

Curated by ChEMBL
LigandPNGBDBM50416570(CHEMBL1215819)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human RAD51 assessed as dissociation of protein/single-stranded poly-(d-epsilonA) complex formation by fluorescence polarimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4RV5PubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Frontier Research Center for Genome & Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50184758((3aS,4S,7R,7aR)-1,6-didodecyl-2,7-bis(methoxycarbo...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of DNA polymerase alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8RF8PubMed
TargetDNA polymerase beta(Homo sapiens (Human))
The University of Manchester

Curated by ChEMBL
LigandPNGBDBM50184757((3aR,4R,7S,7aS)-7-ethyl 2,4-dimethyl 3,5-dihexadec...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8RF8PubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Frontier Research Center for Genome & Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50184755((3aS,4S,7R,7aR)-1,6-dihexadecyl-2,7-bis(methoxycar...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of DNA polymerase alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8RF8PubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
Centre National de la Recherche Scientifique& Universite de Nantes

Curated by ChEMBL
LigandPNGBDBM50416568(CHEMBL1215817)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human RAD51 assessed as dissociation of protein/single-stranded oligo(AGT)12 complex formation by fluorescence polarimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4RV5PubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
Centre National de la Recherche Scientifique& Universite de Nantes

Curated by ChEMBL
LigandPNGBDBM50416561(CHEMBL1215810)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human RAD51 assessed as dissociation of protein/single-stranded DNA complex formation by fluorescence polarimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4RV5PubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Frontier Research Center for Genome & Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50184757((3aR,4R,7S,7aS)-7-ethyl 2,4-dimethyl 3,5-dihexadec...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of DNA polymerase alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8RF8PubMed
TargetDNA polymerase beta(Homo sapiens (Human))
The University of Manchester

Curated by ChEMBL
LigandPNGBDBM50184758((3aS,4S,7R,7aR)-1,6-didodecyl-2,7-bis(methoxycarbo...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8RF8PubMed
TargetDNA polymerase beta(Homo sapiens (Human))
The University of Manchester

Curated by ChEMBL
LigandPNGBDBM50184756((3aR,4S,7S,7aS)-7-ethyl 2,4-dimethyl 3,5-dihexadec...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8RF8PubMed
TargetDNA nucleotidylexotransferase(Homo sapiens (Human))
The University of Manchester

Curated by ChEMBL
LigandPNGBDBM50184755((3aS,4S,7R,7aR)-1,6-dihexadecyl-2,7-bis(methoxycar...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human TdTMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8RF8PubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
Centre National de la Recherche Scientifique& Universite de Nantes

Curated by ChEMBL
LigandPNGBDBM50416568(CHEMBL1215817)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human RAD51 assessed as dissociation of protein/single-stranded poly-(d-epsilonA) complex formation by fluorescence polarimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4RV5PubMed
TargetDNA nucleotidylexotransferase(Homo sapiens (Human))
The University of Manchester

Curated by ChEMBL
LigandPNGBDBM50143524((3aR,4R,7R,7aS)-3,5-Dihexadecyl-3a,4,7,7a-tetrahyd...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibitory activity of the compound against human terminal deoxynucleotidyltransferaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W095C3PubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
Centre National de la Recherche Scientifique& Universite de Nantes

Curated by ChEMBL
LigandPNGBDBM50416569(CHEMBL1215818)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human RAD51 assessed as dissociation of protein/single-stranded oligo(AGT)12 complex formation by fluorescence polarimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4RV5PubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
Centre National de la Recherche Scientifique& Universite de Nantes

Curated by ChEMBL
LigandPNGBDBM50416566(CHEMBL1215815)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human RAD51 assessed as dissociation of protein/single-stranded oligo(AGT)12 complex formation by fluorescence polarimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4RV5PubMed
TargetDNA polymerase beta(Homo sapiens (Human))
The University of Manchester

Curated by ChEMBL
LigandPNGBDBM50184755((3aS,4S,7R,7aR)-1,6-dihexadecyl-2,7-bis(methoxycar...)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8RF8PubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Frontier Research Center for Genome & Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50184752((3aS,4S,7R,7aR)-1,6-dihexadecyl-2,7-bis(isopropoxy...)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of DNA polymerase alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8RF8PubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
Centre National de la Recherche Scientifique& Universite de Nantes

Curated by ChEMBL
LigandPNGBDBM50416562(CHEMBL1215811)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human RAD51 assessed as dissociation of protein/single-stranded DNA complex formation by fluorescence polarimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4RV5PubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Frontier Research Center for Genome & Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50184756((3aR,4S,7S,7aS)-7-ethyl 2,4-dimethyl 3,5-dihexadec...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of DNA polymerase alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8RF8PubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Frontier Research Center for Genome & Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50184754((E)-methyl-3,6-dioxo-4-docosenoate | CHEMBL425779)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of DNA polymerase alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8RF8PubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Frontier Research Center for Genome & Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50143526(CHEMBL366792 | Untenone A)copy SMILEScopy InChI
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of DNA polymerase alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8RF8PubMed
TargetDNA polymerase beta(Homo sapiens (Human))
The University of Manchester

Curated by ChEMBL
LigandPNGBDBM50184752((3aS,4S,7R,7aR)-1,6-dihexadecyl-2,7-bis(isopropoxy...)copy SMILEScopy InChI
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8RF8PubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
Centre National de la Recherche Scientifique& Universite de Nantes

Curated by ChEMBL
LigandPNGBDBM50416569(CHEMBL1215818)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human RAD51 assessed as dissociation of protein/single-stranded poly-(d-epsilonA) complex formation by fluorescence polarimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4RV5PubMed
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