Compile Data Set for Download or QSAR
Found 420 with Last Name = 'sexton' and Initial = 'k'
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50382321(CHEMBL2024688)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of ALK5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04H9PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50382322(CHEMBL2024689)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of ALK5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04H9PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50191486(CHEMBL3959248)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Irreversible inhibition of GST-tagged ERBB4 (unknown origin) (Gly-259 to Gly-690 residues) expressed in baculovirus infected Sf9 insect cells assesse...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VB3PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50191587(CHEMBL3968417)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Irreversible inhibition of full length human ERBB1 autophosphorylation transfected in EGF-stimulated mouse NIH/3T3 cells incubated for 2 hrs followed...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VB3PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50382324(CHEMBL2024691)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of ALK5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04H9PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50191661(CHEMBL3890186)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Irreversible inhibition of GST-tagged ERBB4 (unknown origin) (Gly-259 to Gly-690 residues) expressed in baculovirus infected Sf9 insect cells assesse...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VB3PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50191654(CHEMBL3932176)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Irreversible inhibition of full length human ERBB1 autophosphorylation transfected in EGF-stimulated mouse NIH/3T3 cells incubated for 2 hrs followed...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VB3PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50191495(CHEMBL3896779)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Irreversible inhibition of GST-tagged ERBB4 (unknown origin) (Gly-259 to Gly-690 residues) expressed in baculovirus infected Sf9 insect cells assesse...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VB3PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50191664(CHEMBL3958006)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Irreversible inhibition of full length human ERBB1 autophosphorylation transfected in EGF-stimulated mouse NIH/3T3 cells incubated for 2 hrs followed...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VB3PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50191668(CHEMBL3950549)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Irreversible inhibition of GST-tagged ERBB1 (unknown origin) (Met-668 to Ala-1211 residues) expressed in baculovirus infected Sf9 insect cells assess...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VB3PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50191587(CHEMBL3968417)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Irreversible inhibition of GST-tagged ERBB1 (unknown origin) (Met-668 to Ala-1211 residues) expressed in baculovirus infected Sf9 insect cells assess...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VB3PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM4779(CHEMBL31965 | CHEMBL545315 | CI-1033 | Canertinib ...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Irreversible inhibition of full length human ERBB1 autophosphorylation transfected in EGF-stimulated mouse NIH/3T3 cells incubated for 2 hrs followed...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VB3PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50191489(CHEMBL3942228)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Irreversible inhibition of full length human ERBB1 autophosphorylation transfected in EGF-stimulated mouse NIH/3T3 cells incubated for 2 hrs followed...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VB3PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50191488(CHEMBL3930506)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Irreversible inhibition of full length human ERBB1 autophosphorylation transfected in EGF-stimulated mouse NIH/3T3 cells incubated for 2 hrs followed...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VB3PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50191587(CHEMBL3968417)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Irreversible inhibition of GST-tagged ERBB2 (unknown origin) (Ile-675 to Val-1256 residues) expressed in baculovirus infected Sf9 insect cells assess...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VB3PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50191640(CHEMBL3930316)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Irreversible inhibition of GST-tagged ERBB1 (unknown origin) (Met-668 to Ala-1211 residues) expressed in baculovirus infected Sf9 insect cells assess...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VB3PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM4779(CHEMBL31965 | CHEMBL545315 | CI-1033 | Canertinib ...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Irreversible inhibition of GST-tagged ERBB1 (unknown origin) (Met-668 to Ala-1211 residues) expressed in baculovirus infected Sf9 insect cells assess...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VB3PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50382320(CHEMBL2024687)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of ALK5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04H9PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50191654(CHEMBL3932176)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Irreversible inhibition of GST-tagged ERBB4 (unknown origin) (Gly-259 to Gly-690 residues) expressed in baculovirus infected Sf9 insect cells assesse...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VB3PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50191589(CHEMBL3986103)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Irreversible inhibition of GST-tagged ERBB4 (unknown origin) (Gly-259 to Gly-690 residues) expressed in baculovirus infected Sf9 insect cells assesse...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VB3PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50191641(CHEMBL3949347)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Irreversible inhibition of GST-tagged ERBB4 (unknown origin) (Gly-259 to Gly-690 residues) expressed in baculovirus infected Sf9 insect cells assesse...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VB3PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50191655(CHEMBL3970330)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Irreversible inhibition of GST-tagged ERBB4 (unknown origin) (Gly-259 to Gly-690 residues) expressed in baculovirus infected Sf9 insect cells assesse...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VB3PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Irreversible inhibition of GST-tagged ERBB1 (unknown origin) (Met-668 to Ala-1211 residues) expressed in baculovirus infected Sf9 insect cells assess...More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50191502(CHEMBL3981551)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Irreversible inhibition of GST-tagged ERBB4 (unknown origin) (Gly-259 to Gly-690 residues) expressed in baculovirus infected Sf9 insect cells assesse...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VB3PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50191641(CHEMBL3949347)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Irreversible inhibition of full length human ERBB1 autophosphorylation transfected in EGF-stimulated mouse NIH/3T3 cells incubated for 2 hrs followed...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VB3PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50191481(CHEMBL3948267)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Irreversible inhibition of full length human ERBB1 autophosphorylation transfected in EGF-stimulated mouse NIH/3T3 cells incubated for 2 hrs followed...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VB3PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50191586(CHEMBL3977504)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Irreversible inhibition of GST-tagged ERBB4 (unknown origin) (Gly-259 to Gly-690 residues) expressed in baculovirus infected Sf9 insect cells assesse...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VB3PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50191479(CHEMBL3958482)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Irreversible inhibition of GST-tagged ERBB4 (unknown origin) (Gly-259 to Gly-690 residues) expressed in baculovirus infected Sf9 insect cells assesse...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VB3PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50191646(CHEMBL3923228)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Irreversible inhibition of full length human ERBB1 autophosphorylation transfected in EGF-stimulated mouse NIH/3T3 cells incubated for 2 hrs followed...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VB3PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50382318(CHEMBL2024685)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of ALK5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04H9PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50382319(CHEMBL2024686)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of ALK5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04H9PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50191646(CHEMBL3923228)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Irreversible inhibition of GST-tagged ERBB4 (unknown origin) (Gly-259 to Gly-690 residues) expressed in baculovirus infected Sf9 insect cells assesse...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VB3PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50191489(CHEMBL3942228)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Irreversible inhibition of GST-tagged ERBB4 (unknown origin) (Gly-259 to Gly-690 residues) expressed in baculovirus infected Sf9 insect cells assesse...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VB3PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50191497(CHEMBL3921129)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Irreversible inhibition of GST-tagged ERBB4 (unknown origin) (Gly-259 to Gly-690 residues) expressed in baculovirus infected Sf9 insect cells assesse...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VB3PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50191643(CHEMBL3941823)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Irreversible inhibition of GST-tagged ERBB4 (unknown origin) (Gly-259 to Gly-690 residues) expressed in baculovirus infected Sf9 insect cells assesse...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VB3PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50191593(CHEMBL3967962)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Irreversible inhibition of GST-tagged ERBB4 (unknown origin) (Gly-259 to Gly-690 residues) expressed in baculovirus infected Sf9 insect cells assesse...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VB3PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50191498(CHEMBL3907533)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Irreversible inhibition of full length human ERBB1 autophosphorylation transfected in EGF-stimulated mouse NIH/3T3 cells incubated for 2 hrs followed...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VB3PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50191486(CHEMBL3959248)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Irreversible inhibition of GST-tagged ERBB2 (unknown origin) (Ile-675 to Val-1256 residues) expressed in baculovirus infected Sf9 insect cells assess...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VB3PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50191645(CHEMBL3971413)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Irreversible inhibition of GST-tagged ERBB4 (unknown origin) (Gly-259 to Gly-690 residues) expressed in baculovirus infected Sf9 insect cells assesse...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VB3PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50191475(CHEMBL3962365)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Irreversible inhibition of GST-tagged ERBB4 (unknown origin) (Gly-259 to Gly-690 residues) expressed in baculovirus infected Sf9 insect cells assesse...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VB3PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50191481(CHEMBL3948267)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Irreversible inhibition of GST-tagged ERBB4 (unknown origin) (Gly-259 to Gly-690 residues) expressed in baculovirus infected Sf9 insect cells assesse...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VB3PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50191644(CHEMBL3969056)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Irreversible inhibition of GST-tagged ERBB4 (unknown origin) (Gly-259 to Gly-690 residues) expressed in baculovirus infected Sf9 insect cells assesse...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VB3PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50382325(CHEMBL2024693)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of ALK5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04H9PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50191661(CHEMBL3890186)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Irreversible inhibition of GST-tagged ERBB2 (unknown origin) (Ile-675 to Val-1256 residues) expressed in baculovirus infected Sf9 insect cells assess...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VB3PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50191476(CHEMBL3904257)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Irreversible inhibition of GST-tagged ERBB4 (unknown origin) (Gly-259 to Gly-690 residues) expressed in baculovirus infected Sf9 insect cells assesse...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VB3PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50191485(CHEMBL3914227)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Irreversible inhibition of GST-tagged ERBB4 (unknown origin) (Gly-259 to Gly-690 residues) expressed in baculovirus infected Sf9 insect cells assesse...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VB3PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50191486(CHEMBL3959248)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Irreversible inhibition of full length human ERBB1 autophosphorylation transfected in EGF-stimulated mouse NIH/3T3 cells incubated for 2 hrs followed...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VB3PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50353536(CHEMBL1830778)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Antagonist activity at human androgen receptor by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21836WZPubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50382323(CHEMBL2024690)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of ALK5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04H9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM112499(DACOMITINIB | US8623883, No. 2 | WO2022090481, Exa...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Irreversible inhibition of full length human ERBB1 autophosphorylation transfected in EGF-stimulated mouse NIH/3T3 cells incubated for 2 hrs followed...More data for this Ligand-Target Pair
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