Compile Data Set for Download or QSAR
Found 25 with Last Name = 'sheth' and Initial = 'k'
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Sun Pharma Advanced Research Company Ltd

Curated by ChEMBL
LigandPNGBDBM50355462(CHEMBL1835559)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of TACE in human whole blood assessed as reduction of of LPS-induced TNFalpha production pretreated 15 mins before LPS challenge measured ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ11FFPubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Sun Pharma Advanced Research Company Ltd

Curated by ChEMBL
LigandPNGBDBM50355463(CHEMBL1835560)copy SMILEScopy InChI
Affinity DataIC50: 74nMAssay Description:Inhibition of TACE in human whole blood assessed as reduction of of LPS-induced TNFalpha production pretreated 15 mins before LPS challenge measured ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ11FFPubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Sun Pharma Advanced Research Company Ltd

Curated by ChEMBL
LigandPNGBDBM50355458(CHEMBL1835555)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of TACE in human whole blood assessed as reduction of of LPS-induced TNFalpha production pretreated 15 mins before LPS challenge measured ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ11FFPubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Sun Pharma Advanced Research Company Ltd

Curated by ChEMBL
LigandPNGBDBM50355460(CHEMBL1835557)copy SMILEScopy InChI
Affinity DataIC50: 126nMAssay Description:Inhibition of TACE in human whole blood assessed as reduction of of LPS-induced TNFalpha production pretreated 15 mins before LPS challenge measured ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ11FFPubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Sun Pharma Advanced Research Company Ltd

Curated by ChEMBL
LigandPNGBDBM26806((3R,4R)-3-N-hydroxy-4-N-(4-{[2-(trifluoromethyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of TACE in human whole blood assessed as reduction of of LPS-induced TNFalpha production pretreated 15 mins before LPS challenge measured ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ11FFPubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Sun Pharma Advanced Research Company Ltd

Curated by ChEMBL
LigandPNGBDBM50355459(CHEMBL1835556)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of TACE in human whole blood assessed as reduction of of LPS-induced TNFalpha production pretreated 15 mins before LPS challenge measured ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ11FFPubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Sun Pharma Advanced Research Company Ltd

Curated by ChEMBL
LigandPNGBDBM50355461(CHEMBL1835558)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of TACE in human whole blood assessed as reduction of of LPS-induced TNFalpha production pretreated 15 mins before LPS challenge measured ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ11FFPubMed
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics, Inc.

US Patent
LigandPNGBDBM190533(US9181184, 19)copy SMILEScopy InChI
Affinity DataEC50:  3.72E+5nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43RWBUS Patent
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics, Inc.

US Patent
LigandPNGBDBM190534(US9181184, 20)copy SMILEScopy InChI
Affinity DataEC50:  4.68E+5nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43RWBUS Patent
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics, Inc.

US Patent
LigandPNGBDBM190535(US9181184, 21)copy SMILEScopy InChI
Affinity DataEC50:  2.10E+5nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43RWBUS Patent
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics, Inc.

US Patent
LigandPNGBDBM190536(US9181184, 23)copy SMILEScopy InChI
Affinity DataEC50:  1.21E+5nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43RWBUS Patent
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics, Inc.

US Patent
LigandPNGBDBM190537(US9181184, 24)copy SMILEScopy InChI
Affinity DataEC50:  7.71E+4nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43RWBUS Patent
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics, Inc.

US Patent
LigandPNGBDBM190538(US9181184, 25)copy SMILEScopy InChI
Affinity DataEC50:  6.65E+4nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43RWBUS Patent
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics, Inc.

US Patent
LigandPNGBDBM190539(US9181184, 26)copy SMILEScopy InChI
Affinity DataEC50:  6.60E+3nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43RWBUS Patent
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics, Inc.

US Patent
LigandPNGBDBM190540(US9181184, 27)copy SMILEScopy InChI
Affinity DataEC50:  1.73E+4nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43RWBUS Patent
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics, Inc.

US Patent
LigandPNGBDBM18364((2R,3R,4R,5S,6R)-2-(hydroxymethyl)-6-nonylpiperidi...)copy SMILEScopy InChI
Affinity DataEC50:  7.00E+3nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43RWBUS Patent
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics, Inc.

US Patent
LigandPNGBDBM50259956(2,6-Bis-hydroxymethyl-piperidine-3,4,5-triol | CHE...)copy SMILEScopy InChI
Affinity DataEC50:  2.81E+5nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43RWBUS Patent
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics, Inc.

US Patent
LigandPNGBDBM190531(US9181184, 17 | US9181184, 18)copy SMILEScopy InChI
Affinity DataEC50:  1.04E+5nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43RWBUS Patent
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics, Inc.

US Patent
LigandPNGBDBM190531(US9181184, 17 | US9181184, 18)copy SMILEScopy InChI
Affinity DataEC50:  6.53E+5nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43RWBUS Patent
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics, Inc.

US Patent
LigandPNGBDBM190530(US9181184, 16)copy SMILEScopy InChI
Affinity DataEC50:  6.97E+4nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43RWBUS Patent
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics, Inc.

US Patent
LigandPNGBDBM190529(US9181184, 15)copy SMILEScopy InChI
Affinity DataEC50:  5.84E+5nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43RWBUS Patent
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics, Inc.

US Patent
LigandPNGBDBM190528(US9181184, 11)copy SMILEScopy InChI
Affinity DataEC50:  4.77E+4nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43RWBUS Patent
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics, Inc.

US Patent
LigandPNGBDBM18355((2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-...)copy SMILEScopy InChI
Affinity DataEC50:  1.18E+4nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43RWBUS Patent
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics, Inc.

US Patent
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)copy SMILEScopy InChI
Affinity DataEC50:  9.88E+4nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43RWBUS Patent
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics, Inc.

US Patent
LigandPNGBDBM18353((2R,3R,4R,5S)-2-(hydroxymethyl)-1-methylpiperidine...)copy SMILEScopy InChI
Affinity DataEC50:  7.45E+4nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43RWBUS Patent