Compile Data Set for Download or QSAR
Found 816 with Last Name = 'thiyagarajan' and Initial = 'k'
TargetAP2-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM311193((S)-1-(2-(difluoromethyl)-4-(2-(difluoromethyl)pyr...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63RT2PubMed
TargetAP2-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM311206((S)-1-(2-(difluoromethyl)-4-(2-methylpyridin-4-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63RT2PubMed
TargetAP2-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM321130((S)-8-((2-amino-2,4-dimethylpentyl)oxy)-7-chloro-6...)copy SMILEScopy InChI
Affinity DataIC50: 0.410nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2222WVNUS Patent
TargetAP2-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM311199((S)-2,4-dimethyl-1-(4-(pyridin-4-yl)-2-(trifluorom...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63RT2PubMed
TargetAP2-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM311192((S)-2-((2-amino-2,4-dimethylpentyl)oxy)-5-(2-(difl...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63RT2PubMed
TargetAP2-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM311191((S)-1-(4-(2-(difluoromethyl)pyridin-4-yl)-2-(trifl...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63RT2PubMed
TargetAP2-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM321107((S)-ethyl (8-((2-amino-2,4-dimethylpentyl)oxy)-6H-...)copy SMILEScopy InChI
Affinity DataIC50: 0.620nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2222WVNUS Patent
TargetAP2-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM311270((S)-1-(2-cyclopropyl-4-(2-(difluoromethyl)pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63RT2PubMed
TargetAP2-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM321129((S)-8-((2-amino-2,4-dimethylpentyl)oxy)-6H-isochro...)copy SMILEScopy InChI
Affinity DataIC50: 0.740nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2222WVNUS Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM510974(5-methyl-1-[4-(1-methyl- 1H-pyrazol-4-yl)phenyl]- ...)copy SMILES
Affinity DataIC50: 0.800nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN0DWX
TargetAP2-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM311206((S)-1-(2-(difluoromethyl)-4-(2-methylpyridin-4-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of AKK1 in HEK293F cells assessed as reduction in phospho mu2 formation incubated for 3 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63RT2PubMed
TargetAP2-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM311166( (S)-2-((2-amino-4-methylpentyl)oxy)-5-(2-methylpy...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63RT2PubMed
TargetAP2-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM321131((S)-methyl (8-((2-amino-2,4-dimethylpentyl)oxy)-7-...)copy SMILEScopy InChI
Affinity DataIC50: 0.810nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2222WVNUS Patent
TargetAP2-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM311201((S)-2,4-dimethyl-1-(4-(2-methylpyridin-4-yl)-2-(tr...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63RT2PubMed
TargetAP2-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM311193((S)-1-(2-(difluoromethyl)-4-(2-(difluoromethyl)pyr...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of AKK1 in HEK293F cells assessed as reduction in phospho mu2 formation incubated for 3 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63RT2PubMed
TargetAP2-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM321111((S)-methyl (8-((2-amino-2,4-dimethylpentyl)oxy)-7-...)copy SMILEScopy InChI
Affinity DataIC50: 0.910nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2222WVNUS Patent
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50074818(CHEMBL3410163)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92D18PubMed
TargetNeurogenic locus notch homolog protein 3(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50074693(CHEMBL3410162)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of Notch3 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92D18PubMed
TargetNeurogenic locus notch homolog protein 3(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50074796(CHEMBL3410169)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of Notch3 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92D18PubMed
TargetNeurogenic locus notch homolog protein 2(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50074694(CHEMBL3410161)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of Notch2 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92D18PubMed
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50074771(CHEMBL3410153)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92D18PubMed
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50074796(CHEMBL3410169)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92D18PubMed
TargetNeurogenic locus notch homolog protein 3(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50074771(CHEMBL3410153)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of Notch3 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92D18PubMed
TargetNeurogenic locus notch homolog protein 3(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50074799(CHEMBL3410167)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of Notch3 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92D18PubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM510980(1-(2,2-difluoroethyl)-6-(2- hydroxy-2- methylpropo...)copy SMILES
Affinity DataIC50: 1.10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN0DWX
TargetAP2-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM321106((R)-ethyl (8-((2-amino-2,4-dimethylpentyl)oxy)-6H-...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2222WVNUS Patent
TargetAP2-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM311304(((S)-1-((6-chloro-2′-(difluoromethyl)-[2,4&#...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63RT2PubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM510981(1-(2,2-difluoroethyl)-6-(2- fluoro-2-methylpropoxy...)copy SMILES
Affinity DataIC50: 1.60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN0DWX
TargetAP2-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM321087((S)-8-((2-amino-2,4-dimethylpentyl)oxy)-9-chloro-4...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2222WVNUS Patent
TargetAP2-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM311337((S)-1-((5-(difluoromethyl)-2′-methyl-[3,4...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63RT2PubMed
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50074799(CHEMBL3410167)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92D18PubMed
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50074798(CHEMBL3410168)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92D18PubMed
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50074795(CHEMBL3410170)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92D18PubMed
TargetAP2-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM311267((S)-1-((2′,6-bis(difluoromethyl)-[2,4′...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of AKK1 in HEK293F cells assessed as reduction in phospho mu2 formation incubated for 3 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63RT2PubMed
TargetAP2-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM311267((S)-1-((2′,6-bis(difluoromethyl)-[2,4′...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63RT2PubMed
TargetNeurogenic locus notch homolog protein 3(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50074795(CHEMBL3410170)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of Notch3 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92D18PubMed
TargetNeurogenic locus notch homolog protein 3(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50074798(CHEMBL3410168)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of Notch3 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92D18PubMed
TargetNeurogenic locus notch homolog protein 3(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50074818(CHEMBL3410163)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of Notch3 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92D18PubMed
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50074784(CHEMBL3410151)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92D18PubMed
TargetAP2-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM321098((S)¿N-(8-((2-amino-4-methylpentyl)oxy)-6H-isochrom...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2222WVNUS Patent
TargetAP2-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM321120((S)-isopropyl (8-((2-amino-2,4-dimethylpentyl)oxy)...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2222WVNUS Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM510905(6-(2-hydroxy-2- methylpropoxy)-N- [(aR)-6-({6- car...)copy SMILES
Affinity DataIC50: 2.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN0DWX
TargetAP2-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM311200((S)-1-(4-(2-fluoropyridin-4-yl)-2-(trifluoromethyl...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63RT2PubMed
TargetAP2-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM321118((S)-1-((4-chloro-6H-isochromeno[3,4-c]pyridin-8-yl...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2222WVNUS Patent
TargetAP2-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM311205((S)-1-(2-cyclopropyl-4-(2-methylpyridin-4-yl)pheno...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63RT2PubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM510975(1-(difluoromethyl)-5-(4- methanesulfonylphenyl)- N...)copy SMILES
Affinity DataIC50: 2.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN0DWX
TargetAP2-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM321103((S)¿N-(8-((2-amino-2,4-dimethylpentyl)oxy)-6H-isoc...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2222WVNUS Patent
TargetAP2-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50586144(CHEMBL5074638)copy SMILES
Affinity DataIC50: 2.5nMAssay Description:Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63RT2PubMed
TargetAP2-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM321074(8-((2-amino-2,4-dimethylpentyl)oxy)benzo[c][1,7]na...)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2222WVNUS Patent
TargetAP2-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM321102(N-(8-((2-amino-2,4-dimethylpentyl)oxy)-6H-isochrom...)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2222WVNUS Patent
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