Found 258 with Last Name = 'tsuboi' and Initial = 'k' TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:In situ inhibition of ABHD6 in mouse Neuro2a cells after 4 hrs by ABPP-SILAC-based LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:In situ inhibition of ABHD6 in mouse Neuro2a cells after 4 hrs by ABPP-SILAC-based LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:In situ inhibition of ABHD6 in mouse Neuro2a cells after 4 hrs by ABPP-SILAC-based LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.210nMAssay Description:In situ inhibition of ABHD6 in mouse Neuro2a cells after 4 hrs by gel-based competitive ABPP assayMore data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.240nMAssay Description:In situ inhibition of ABHD6 in mouse Neuro2a cells after 4 hrs by gel-based competitive ABPP assayMore data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.310nMAssay Description:In situ inhibition of ABHD6 in mouse Neuro2a cells after 4 hrs by gel-based competitive ABPP assayMore data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.820nMAssay Description:Inhibition of ABHD6 in FP-rhodamine-labelled mouse brain membrane preincubated for 30 mins followed by FP-rhodamine labelling measured after 30 mins ...More data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of ABHD6 in FP-rhodamine-labelled mouse brain membrane preincubated for 30 mins followed by FP-rhodamine labelling measured after 30 mins ...More data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of ABHD6 in FP-rhodamine-labelled mouse brain membrane preincubated for 30 mins followed by FP-rhodamine labelling measured after 30 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human liver mitochondrial KMO assessed as reduction in 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 min...More data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.90nMAssay Description:Inhibition of recombinant mouse ABHD6 expressed in HEK293T using 2-arachidonoylglycerol preincubated for 30 mins followed by substrate addition measu...More data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human liver mitochondrial KMO assessed as reduction in 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 min...More data for this Ligand-Target Pair
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Daiichi Sankyo Company, Limited
US Patent
Daiichi Sankyo Company, Limited
US Patent
Affinity DataIC50: 6nMT: 2°CAssay Description:A recombinant human CETP protein (manufactured by Roar Biomedical Inc.;
4.5 ng), the acceptor lipoprotein described in (2) above (32.5 ug) and
5,5'...More data for this Ligand-Target Pair
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Daiichi Sankyo Company, Limited
US Patent
Daiichi Sankyo Company, Limited
US Patent
Affinity DataIC50: 6nMT: 2°CAssay Description:A recombinant human CETP protein (manufactured by Roar Biomedical Inc.;
4.5 ng), the acceptor lipoprotein described in (2) above (32.5 ug) and
5,5'...More data for this Ligand-Target Pair
Affinity DataIC50: 6.10nMAssay Description:Inhibition of human liver mitochondrial KMO assessed as reduction in 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 min...More data for this Ligand-Target Pair
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Daiichi Sankyo Company, Limited
US Patent
Daiichi Sankyo Company, Limited
US Patent
Affinity DataIC50: 8nMT: 2°CAssay Description:A recombinant human CETP protein (manufactured by Roar Biomedical Inc.;
4.5 ng), the acceptor lipoprotein described in (2) above (32.5 ug) and
5,5'...More data for this Ligand-Target Pair
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Daiichi Sankyo Company, Limited
US Patent
Daiichi Sankyo Company, Limited
US Patent
Affinity DataIC50: 9nMT: 2°CAssay Description:A recombinant human CETP protein (manufactured by Roar Biomedical Inc.;
4.5 ng), the acceptor lipoprotein described in (2) above (32.5 ug) and
5,5'...More data for this Ligand-Target Pair
Affinity DataIC50: 9.10nMAssay Description:Inhibition of human liver mitochondrial KMO assessed as reduction in 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 min...More data for this Ligand-Target Pair
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Daiichi Sankyo Company, Limited
US Patent
Daiichi Sankyo Company, Limited
US Patent
Affinity DataIC50: 10nMT: 2°CAssay Description:A recombinant human CETP protein (manufactured by Roar Biomedical Inc.;
4.5 ng), the acceptor lipoprotein described in (2) above (32.5 ug) and
5,5'...More data for this Ligand-Target Pair
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Daiichi Sankyo Company, Limited
US Patent
Daiichi Sankyo Company, Limited
US Patent
Affinity DataIC50: 11nMT: 2°CAssay Description:A recombinant human CETP protein (manufactured by Roar Biomedical Inc.;
4.5 ng), the acceptor lipoprotein described in (2) above (32.5 ug) and
5,5'...More data for this Ligand-Target Pair
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Daiichi Sankyo Company, Limited
US Patent
Daiichi Sankyo Company, Limited
US Patent
Affinity DataIC50: 13nMT: 2°CAssay Description:A recombinant human CETP protein (manufactured by Roar Biomedical Inc.;
4.5 ng), the acceptor lipoprotein described in (2) above (32.5 ug) and
5,5'...More data for this Ligand-Target Pair
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Daiichi Sankyo Company, Limited
US Patent
Daiichi Sankyo Company, Limited
US Patent
Affinity DataIC50: 13nMT: 2°CAssay Description:A recombinant human CETP protein (manufactured by Roar Biomedical Inc.;
4.5 ng), the acceptor lipoprotein described in (2) above (32.5 ug) and
5,5'...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human liver mitochondrial KMO assessed as reduction in 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 min...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human liver mitochondrial KMO assessed as reduction in 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 min...More data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant mouse ABHD6 expressed in HEK293T using 2-arachidonoylglycerol preincubated for 30 mins followed by substrate addition measu...More data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant mouse ABHD6 expressed in HEK293T using 2-arachidonoylglycerol preincubated for 30 mins followed by substrate addition measu...More data for this Ligand-Target Pair
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Daiichi Sankyo Company, Limited
US Patent
Daiichi Sankyo Company, Limited
US Patent
Affinity DataIC50: 16nMT: 2°CAssay Description:A recombinant human CETP protein (manufactured by Roar Biomedical Inc.;
4.5 ng), the acceptor lipoprotein described in (2) above (32.5 ug) and
5,5'...More data for this Ligand-Target Pair
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Daiichi Sankyo Company, Limited
US Patent
Daiichi Sankyo Company, Limited
US Patent
Affinity DataIC50: 16nMT: 2°CAssay Description:A recombinant human CETP protein (manufactured by Roar Biomedical Inc.;
4.5 ng), the acceptor lipoprotein described in (2) above (32.5 ug) and
5,5'...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of human liver mitochondrial KMO assessed as reduction in 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 min...More data for this Ligand-Target Pair
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Daiichi Sankyo Company, Limited
US Patent
Daiichi Sankyo Company, Limited
US Patent
Affinity DataIC50: 19nMT: 2°CAssay Description:A recombinant human CETP protein (manufactured by Roar Biomedical Inc.;
4.5 ng), the acceptor lipoprotein described in (2) above (32.5 ug) and
5,5'...More data for this Ligand-Target Pair
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Daiichi Sankyo Company, Limited
US Patent
Daiichi Sankyo Company, Limited
US Patent
Affinity DataIC50: 19nMT: 2°CAssay Description:A recombinant human CETP protein (manufactured by Roar Biomedical Inc.;
4.5 ng), the acceptor lipoprotein described in (2) above (32.5 ug) and
5,5'...More data for this Ligand-Target Pair
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Daiichi Sankyo Company, Limited
US Patent
Daiichi Sankyo Company, Limited
US Patent
Affinity DataIC50: 19nMT: 2°CAssay Description:A recombinant human CETP protein (manufactured by Roar Biomedical Inc.;
4.5 ng), the acceptor lipoprotein described in (2) above (32.5 ug) and
5,5'...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human liver mitochondrial KMO assessed as reduction in 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 min...More data for this Ligand-Target Pair
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Daiichi Sankyo Company, Limited
US Patent
Daiichi Sankyo Company, Limited
US Patent
Affinity DataIC50: 21nMT: 2°CAssay Description:A recombinant human CETP protein (manufactured by Roar Biomedical Inc.;
4.5 ng), the acceptor lipoprotein described in (2) above (32.5 ug) and
5,5'...More data for this Ligand-Target Pair
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Daiichi Sankyo Company, Limited
US Patent
Daiichi Sankyo Company, Limited
US Patent
Affinity DataIC50: 22nMT: 2°CAssay Description:A recombinant human CETP protein (manufactured by Roar Biomedical Inc.;
4.5 ng), the acceptor lipoprotein described in (2) above (32.5 ug) and
5,5'...More data for this Ligand-Target Pair
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Daiichi Sankyo Company, Limited
US Patent
Daiichi Sankyo Company, Limited
US Patent
Affinity DataIC50: 25nMT: 2°CAssay Description:A recombinant human CETP protein (manufactured by Roar Biomedical Inc.;
4.5 ng), the acceptor lipoprotein described in (2) above (32.5 ug) and
5,5'...More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of human liver mitochondrial KMO assessed as reduction in 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 min...More data for this Ligand-Target Pair
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Daiichi Sankyo Company, Limited
US Patent
Daiichi Sankyo Company, Limited
US Patent
Affinity DataIC50: 28nMT: 2°CAssay Description:A recombinant human CETP protein (manufactured by Roar Biomedical Inc.;
4.5 ng), the acceptor lipoprotein described in (2) above (32.5 ug) and
5,5'...More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of human liver mitochondrial KMO assessed as reduction in 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 min...More data for this Ligand-Target Pair
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Daiichi Sankyo Company, Limited
US Patent
Daiichi Sankyo Company, Limited
US Patent
Affinity DataIC50: 29nMT: 2°CAssay Description:A recombinant human CETP protein (manufactured by Roar Biomedical Inc.;
4.5 ng), the acceptor lipoprotein described in (2) above (32.5 ug) and
5,5'...More data for this Ligand-Target Pair
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Daiichi Sankyo Company, Limited
US Patent
Daiichi Sankyo Company, Limited
US Patent
Affinity DataIC50: 31nMT: 2°CAssay Description:A recombinant human CETP protein (manufactured by Roar Biomedical Inc.;
4.5 ng), the acceptor lipoprotein described in (2) above (32.5 ug) and
5,5'...More data for this Ligand-Target Pair
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Daiichi Sankyo Company, Limited
US Patent
Daiichi Sankyo Company, Limited
US Patent
Affinity DataIC50: 32nMT: 2°CAssay Description:A recombinant human CETP protein (manufactured by Roar Biomedical Inc.;
4.5 ng), the acceptor lipoprotein described in (2) above (32.5 ug) and
5,5'...More data for this Ligand-Target Pair
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Daiichi Sankyo Company, Limited
US Patent
Daiichi Sankyo Company, Limited
US Patent
Affinity DataIC50: 32nMT: 2°CAssay Description:A recombinant human CETP protein (manufactured by Roar Biomedical Inc.;
4.5 ng), the acceptor lipoprotein described in (2) above (32.5 ug) and
5,5'...More data for this Ligand-Target Pair
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Daiichi Sankyo Company, Limited
US Patent
Daiichi Sankyo Company, Limited
US Patent
Affinity DataIC50: 32nMT: 2°CAssay Description:A recombinant human CETP protein (manufactured by Roar Biomedical Inc.;
4.5 ng), the acceptor lipoprotein described in (2) above (32.5 ug) and
5,5'...More data for this Ligand-Target Pair
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Daiichi Sankyo Company, Limited
US Patent
Daiichi Sankyo Company, Limited
US Patent
Affinity DataIC50: 33nMT: 2°CAssay Description:A recombinant human CETP protein (manufactured by Roar Biomedical Inc.;
4.5 ng), the acceptor lipoprotein described in (2) above (32.5 ug) and
5,5'...More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of human liver mitochondrial KMO assessed as reduction in 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 min...More data for this Ligand-Target Pair
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Daiichi Sankyo Company, Limited
US Patent
Daiichi Sankyo Company, Limited
US Patent
Affinity DataIC50: 34nMT: 2°CAssay Description:A recombinant human CETP protein (manufactured by Roar Biomedical Inc.;
4.5 ng), the acceptor lipoprotein described in (2) above (32.5 ug) and
5,5'...More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of human liver mitochondrial KMO assessed as reduction in 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 min...More data for this Ligand-Target Pair
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Daiichi Sankyo Company, Limited
US Patent
Daiichi Sankyo Company, Limited
US Patent
Affinity DataIC50: 35nMT: 2°CAssay Description:A recombinant human CETP protein (manufactured by Roar Biomedical Inc.;
4.5 ng), the acceptor lipoprotein described in (2) above (32.5 ug) and
5,5'...More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of human liver mitochondrial KMO assessed as reduction in 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 min...More data for this Ligand-Target Pair
