Compile Data Set for Download or QSAR
Found 74 with Last Name = 'ueta' and Initial = 'k'
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50438462(CHEMBL2414623)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human SGLT2 expressed in CHOK cells assessed as reduction of [14C]alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scinti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9DHVPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50438467(CHEMBL2414618)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human SGLT2 expressed in CHOK cells assessed as reduction of [14C]alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scinti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9DHVPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50446188(CHEMBL3109017)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human SGLT2-mediated [14C]-AMG uptake expressed in CHOK cells preincubated for 10 mins followed by [14C]-AMG addition measured after 12...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0GM7PubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50346265((2R,3R,4S,5S,6R)-2-(3-(4-cyclopropylbenzyl)-4-fluo...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human SGLT2-mediated [14C]-AMG uptake expressed in CHOK cells preincubated for 10 mins followed by [14C]-AMG addition measured after 12...More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50438463(CHEMBL2414622)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human SGLT2 expressed in CHOK cells assessed as reduction of [14C]alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scinti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9DHVPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50446186(CHEMBL3109016)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human SGLT2-mediated [14C]-AMG uptake expressed in CHOK cells preincubated for 10 mins followed by [14C]-AMG addition measured after 12...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0GM7PubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50438465(CHEMBL2414620)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human SGLT2 expressed in CHOK cells assessed as reduction of [14C]alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scinti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9DHVPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50438460(CHEMBL2414617)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human SGLT2 expressed in CHOK cells assessed as reduction of [14C]alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scinti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9DHVPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50326284(1-(beta-D-Glucopyranosyl)-4-methyl-3-(5-(4-fluorop...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scint...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69JSSPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50446185(CHEMBL3109015)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human SGLT2-mediated [14C]-AMG uptake expressed in CHOK cells preincubated for 10 mins followed by [14C]-AMG addition measured after 12...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0GM7PubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50386885(CANAGLIFLOZIN | CANAGLIFLOZIN HYDRATE | US10752604...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human SGLT2 expressed in CHOK cells assessed as reduction of [14C]alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scinti...More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50438464(CHEMBL2414621)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human SGLT2 expressed in CHOK cells assessed as reduction of [14C]alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scinti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9DHVPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50326280(1-(beta-D-Glucopyranosyl)-4-chloro-3-(5-chloro-2-t...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scint...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69JSSPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50441088(CHEMBL2430315)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human SGLT2 expressed in CHOK cells assessed as [14-C]AMG uptake preincubated for 10 mins followed by [14-C]AMG addition measured after...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3GSMPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50446190(CHEMBL3109019)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human SGLT2-mediated [14C]-AMG uptake expressed in CHOK cells preincubated for 10 mins followed by [14C]-AMG addition measured after 12...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0GM7PubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50381537(CHEMBL2017954)copy SMILEScopy InChI
Affinity DataIC50: 5.10nMAssay Description:Inhibition of human SGLT2 expressed in CHOK cells assessed as [14-C]AMG uptake preincubated for 10 mins followed by [14-C]AMG addition measured after...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3GSMPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM20877(3-(1-benzofuran-5-yl)-1-(2-hydroxy-4-methyl-6-{[(2...)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scint...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69JSSPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50446187(CHEMBL3109020)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human SGLT2-mediated [14C]-AMG uptake expressed in CHOK cells preincubated for 10 mins followed by [14C]-AMG addition measured after 12...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0GM7PubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50441082(CHEMBL2430319)copy SMILEScopy InChI
Affinity DataIC50: 7.10nMAssay Description:Inhibition of human SGLT2-mediated [14C]-AMG uptake expressed in CHOK cells preincubated for 10 mins followed by [14C]-AMG addition measured after 12...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0GM7PubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50441082(CHEMBL2430319)copy SMILEScopy InChI
Affinity DataIC50: 7.10nMAssay Description:Inhibition of human SGLT2 expressed in CHOK cells assessed as [14-C]AMG uptake preincubated for 10 mins followed by [14-C]AMG addition measured after...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3GSMPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50438466(CHEMBL2414619)copy SMILEScopy InChI
Affinity DataIC50: 7.30nMAssay Description:Inhibition of human SGLT2 expressed in CHOK cells assessed as reduction of [14C]alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scinti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9DHVPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50326283(1-(beta-D-Glucopyranosyl)-4-methyl-3-(5-(4-fluorop...)copy SMILEScopy InChI
Affinity DataIC50: 8.10nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scint...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69JSSPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50446184(CHEMBL3109014)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human SGLT2-mediated [14C]-AMG uptake expressed in CHOK cells preincubated for 10 mins followed by [14C]-AMG addition measured after 12...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0GM7PubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50326279(1-(beta-D-Glucopyranosyl)-3-(5-ethyl-2-thienylmeth...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scint...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69JSSPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50446189(CHEMBL3109018)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of human SGLT2-mediated [14C]-AMG uptake expressed in CHOK cells preincubated for 10 mins followed by [14C]-AMG addition measured after 12...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0GM7PubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50446186(CHEMBL3109016)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of human SGLT1-mediated [14C]-AMG uptake expressed in CHOK cells preincubated for 10 mins followed by [14C]-AMG addition measured after 12...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0GM7PubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50446182(CHEMBL3109012)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of human SGLT2-mediated [14C]-AMG uptake expressed in CHOK cells preincubated for 10 mins followed by [14C]-AMG addition measured after 12...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0GM7PubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50326282(1-(beta-D-Glucopyranosyl)-4-chloro-3-(2-ethyl-5-py...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scint...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69JSSPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50326281(1-(beta-D-Glucopyranosyl)-4-chloro-3-(1-phenyl-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scint...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69JSSPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50441083(CHEMBL2430321)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:Inhibition of human SGLT2 expressed in CHOK cells assessed as [14-C]AMG uptake preincubated for 10 mins followed by [14-C]AMG addition measured after...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3GSMPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50446183(CHEMBL3109013)copy SMILEScopy InChI
Affinity DataIC50: 93nMAssay Description:Inhibition of human SGLT2-mediated [14C]-AMG uptake expressed in CHOK cells preincubated for 10 mins followed by [14C]-AMG addition measured after 12...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0GM7PubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50441086(CHEMBL2430317)copy SMILEScopy InChI
Affinity DataIC50: 163nMAssay Description:Inhibition of human SGLT2 expressed in CHOK cells assessed as [14-C]AMG uptake preincubated for 10 mins followed by [14-C]AMG addition measured after...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3GSMPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50446187(CHEMBL3109020)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibition of human SGLT1-mediated [14C]-AMG uptake expressed in CHOK cells preincubated for 10 mins followed by [14C]-AMG addition measured after 12...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0GM7PubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50346265((2R,3R,4S,5S,6R)-2-(3-(4-cyclopropylbenzyl)-4-fluo...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibition of human SGLT1-mediated [14C]-AMG uptake expressed in CHOK cells preincubated for 10 mins followed by [14C]-AMG addition measured after 12...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0GM7PubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM20877(3-(1-benzofuran-5-yl)-1-(2-hydroxy-4-methyl-6-{[(2...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scint...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69JSSPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50441087(CHEMBL2430316)copy SMILEScopy InChI
Affinity DataIC50: 381nMAssay Description:Inhibition of human SGLT2 expressed in CHOK cells assessed as [14-C]AMG uptake preincubated for 10 mins followed by [14-C]AMG addition measured after...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3GSMPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50438460(CHEMBL2414617)copy SMILEScopy InChI
Affinity DataIC50: 750nMAssay Description:Inhibition of human SGLT1 expressed in CHOK cells assessed as reduction of [14C]alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scinti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9DHVPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50326284(1-(beta-D-Glucopyranosyl)-4-methyl-3-(5-(4-fluorop...)copy SMILEScopy InChI
Affinity DataIC50: 910nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scint...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69JSSPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50326278(1-(beta-D-Glucopyranosyl)-3-(5-ethyl-2-furylmethyl...)copy SMILEScopy InChI
Affinity DataIC50: 920nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scint...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69JSSPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50441084(CHEMBL2430320)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human SGLT2 expressed in CHOK cells assessed as [14-C]AMG uptake preincubated for 10 mins followed by [14-C]AMG addition measured after...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3GSMPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50441082(CHEMBL2430319)copy SMILEScopy InChI
Affinity DataIC50: 1.96E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHOK cells assessed as [14-C]AMG uptake preincubated for 10 mins followed by [14-C]AMG addition measured after...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3GSMPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50441085(CHEMBL2430318)copy SMILEScopy InChI
Affinity DataIC50: 6.67E+3nMAssay Description:Inhibition of human SGLT2 expressed in CHOK cells assessed as [14-C]AMG uptake preincubated for 10 mins followed by [14-C]AMG addition measured after...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3GSMPubMed
TargetSolute carrier family 2, facilitated glucose transporter member 1(Rattus norvegicus)
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50326284(1-(beta-D-Glucopyranosyl)-4-methyl-3-(5-(4-fluorop...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GLUT1-mediated [3H]2-deoxy-glucose uptake in rat L6 cells after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69JSSPubMed
TargetSolute carrier family 2, facilitated glucose transporter member 1(Rattus norvegicus)
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM20877(3-(1-benzofuran-5-yl)-1-(2-hydroxy-4-methyl-6-{[(2...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GLUT1-mediated [3H]2-deoxy-glucose uptake in rat L6 cells after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69JSSPubMed
TargetHexokinase-4(Rattus norvegicus)
OSI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161690(3-(5-Chloro-thiazol-2-yl)-1-cyclopentylmethyl-1-(3...)copy SMILEScopy InChI
Affinity DataEC50:  2.60E+3nMAssay Description:Effective concentration for glucokinase activation with 5 mM glucoseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2NVCPubMed
TargetHexokinase-4(Rattus norvegicus)
OSI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161689(3-(5-Chloro-thiazol-2-yl)-1-(4-methanesulfonyl-phe...)copy SMILEScopy InChI
Affinity DataEC50:  2.19E+4nMAssay Description:Effective concentration for glucokinase activation with 5 mM glucoseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2NVCPubMed
TargetHexokinase-4(Rattus norvegicus)
OSI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161688(3-(5-Chloro-thiazol-2-yl)-1-(4-methanesulfonyl-phe...)copy SMILEScopy InChI
Affinity DataEC50:  6.60E+3nMAssay Description:Effective concentration for glucokinase activation with 5 mM glucoseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2NVCPubMed
TargetHexokinase-4(Rattus norvegicus)
OSI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161687(3-(5-Chloro-thiazol-2-yl)-1-cyclopentylmethyl-1-(4...)copy SMILEScopy InChI
Affinity DataEC50:  1.50E+3nMAssay Description:Effective concentration for glucokinase activation with 5 mM glucoseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2NVCPubMed
TargetHexokinase-4(Rattus norvegicus)
OSI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161686(3-(5-Chloro-thiazol-2-yl)-1-cyclopentylmethyl-1-(4...)copy SMILEScopy InChI
Affinity DataEC50:  1.30E+3nMAssay Description:Effective concentration for glucokinase activation with 5 mM glucoseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2NVCPubMed
TargetHexokinase-4(Rattus norvegicus)
OSI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161674(3-Cyclopentyl-2-(4-methanesulfonyl-phenyl)-N-thiaz...)copy SMILEScopy InChI
Affinity DataEC50:  2.20E+3nMAssay Description:Effective concentration for glucokinase activation with 5 mM glucoseMore data for this Ligand-Target Pair
Displayed 1 to 50 (of 74 total ) | Next | Last >>
Jump to: