Compile Data Set for Download or QSAR
Found 24 with Last Name = 'vermeire' and Initial = 'k'
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Tibotec BVBA

Curated by ChEMBL
LigandPNGBDBM50204832(4-(2-(5-bromo-2-fluorophenyl)pteridin-4-ylamino)-N...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of TGFBR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2999PubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Tibotec BVBA

Curated by ChEMBL
LigandPNGBDBM50204832(4-(2-(5-bromo-2-fluorophenyl)pteridin-4-ylamino)-N...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of human JNK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2999PubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Tibotec BVBA

Curated by ChEMBL
LigandPNGBDBM50204832(4-(2-(5-bromo-2-fluorophenyl)pteridin-4-ylamino)-N...)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of human VEGFR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2999PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Tibotec BVBA

Curated by ChEMBL
LigandPNGBDBM50204834(2-(5-chloro-2-fluorophenyl)-N-(pyridin-4-yl)pterid...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Inhibition of TGFBR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2999PubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Tibotec BVBA

Curated by ChEMBL
LigandPNGBDBM50204832(4-(2-(5-bromo-2-fluorophenyl)pteridin-4-ylamino)-N...)copy SMILEScopy InChI
Affinity DataIC50: 59nMAssay Description:Inhibition of human JNK3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2999PubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Tibotec BVBA

Curated by ChEMBL
LigandPNGBDBM50204832(4-(2-(5-bromo-2-fluorophenyl)pteridin-4-ylamino)-N...)copy SMILEScopy InChI
Affinity DataIC50: 123nMAssay Description:Inhibition of human VEGFR3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2999PubMed
TargetT-cell surface glycoprotein CD4(Homo sapiens (Human))TBA
LigandPNGBDBM50548974(CHEMBL4747494)copy SMILES
Affinity DataIC50: 130nMAssay Description:Binding affinity to signal peptide of human CD4-YFP expressed in CHO-K1 cells assessed down-modulation of CD4 surface expression incubated for 24 hrs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T3ZPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Tibotec BVBA

Curated by ChEMBL
LigandPNGBDBM50204832(4-(2-(5-bromo-2-fluorophenyl)pteridin-4-ylamino)-N...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of human VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2999PubMed
TargetT-cell surface glycoprotein CD4(Homo sapiens (Human))TBA
LigandPNGBDBM50548980(CHEMBL4791666)copy SMILES
Affinity DataIC50: 220nMAssay Description:Binding affinity to signal peptide of human CD4-YFP expressed in CHO-K1 cells assessed down-modulation of CD4 surface expression incubated for 24 hrs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T3ZPubMed
TargetT-cell surface glycoprotein CD4(Homo sapiens (Human))TBA
LigandPNGBDBM50545414(CHEMBL1852155)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Binding affinity to signal peptide of human CD4-YFP expressed in CHO-K1 cells assessed down-modulation of CD4 surface expression incubated for 24 hrs...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T3ZPubMed
TargetT-cell surface glycoprotein CD4(Homo sapiens (Human))TBA
LigandPNGBDBM50548973(CHEMBL4746252)copy SMILES
Affinity DataIC50: 420nMAssay Description:Binding affinity to signal peptide of human CD4-YFP expressed in CHO-K1 cells assessed down-modulation of CD4 surface expression incubated for 24 hrs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T3ZPubMed
TargetT-cell surface glycoprotein CD4(Homo sapiens (Human))TBA
LigandPNGBDBM50548976(CHEMBL4750983)copy SMILES
Affinity DataIC50: 540nMAssay Description:Binding affinity to signal peptide of human CD4-YFP expressed in CHO-K1 cells assessed down-modulation of CD4 surface expression incubated for 24 hrs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T3ZPubMed
TargetT-cell surface glycoprotein CD4(Homo sapiens (Human))TBA
LigandPNGBDBM50548977(CHEMBL4786809)copy SMILES
Affinity DataIC50: 660nMAssay Description:Binding affinity to signal peptide of human CD4-YFP expressed in CHO-K1 cells assessed down-modulation of CD4 surface expression incubated for 24 hrs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T3ZPubMed
TargetT-cell surface glycoprotein CD4(Homo sapiens (Human))TBA
LigandPNGBDBM50548978(CHEMBL4748787)copy SMILES
Affinity DataIC50: 740nMAssay Description:Binding affinity to signal peptide of human CD4-YFP expressed in CHO-K1 cells assessed down-modulation of CD4 surface expression incubated for 24 hrs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T3ZPubMed
TargetCathepsin S(Homo sapiens (Human))
Tibotec BVBA

Curated by ChEMBL
LigandPNGBDBM50336504((2R,3aR,10Z,11aS,12aR,14aR)-N-(cyclopropylsulfonyl...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of human cathepsin S in human JY cells assessed as p10 accumulation by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z31ZWZPubMed
TargetT-cell surface glycoprotein CD4(Homo sapiens (Human))TBA
LigandPNGBDBM50548975(CHEMBL4758659)copy SMILES
Affinity DataIC50: 830nMAssay Description:Binding affinity to signal peptide of human CD4-YFP expressed in CHO-K1 cells assessed down-modulation of CD4 surface expression incubated for 24 hrs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T3ZPubMed
TargetT-cell surface glycoprotein CD4(Homo sapiens (Human))TBA
LigandPNGBDBM50548968(CHEMBL4755141)copy SMILES
Affinity DataIC50: 860nMAssay Description:Binding affinity to signal peptide of human CD4-YFP expressed in CHO-K1 cells assessed down-modulation of CD4 surface expression incubated for 24 hrs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T3ZPubMed
TargetT-cell surface glycoprotein CD4(Homo sapiens (Human))TBA
LigandPNGBDBM50548969(CHEMBL4783761)copy SMILES
Affinity DataIC50: 950nMAssay Description:Binding affinity to signal peptide of human CD4-YFP expressed in CHO-K1 cells assessed down-modulation of CD4 surface expression incubated for 24 hrs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T3ZPubMed
TargetT-cell surface glycoprotein CD4(Homo sapiens (Human))TBA
LigandPNGBDBM50548972(CHEMBL4782080)copy SMILES
Affinity DataIC50: 1.50E+3nMAssay Description:Binding affinity to signal peptide of human CD4-YFP expressed in CHO-K1 cells assessed down-modulation of CD4 surface expression incubated for 24 hrs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T3ZPubMed
TargetT-cell surface glycoprotein CD4(Homo sapiens (Human))TBA
LigandPNGBDBM50548979(CHEMBL4785236)copy SMILES
Affinity DataIC50: 1.67E+3nMAssay Description:Binding affinity to signal peptide of human CD4-YFP expressed in CHO-K1 cells assessed down-modulation of CD4 surface expression incubated for 24 hrs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T3ZPubMed
TargetT-cell surface glycoprotein CD4(Homo sapiens (Human))TBA
LigandPNGBDBM50548971(CHEMBL4743003)copy SMILES
Affinity DataIC50: 1.88E+3nMAssay Description:Binding affinity to signal peptide of human CD4-YFP expressed in CHO-K1 cells assessed down-modulation of CD4 surface expression incubated for 24 hrs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T3ZPubMed
TargetT-cell surface glycoprotein CD4(Homo sapiens (Human))TBA
LigandPNGBDBM50548967(CHEMBL4783030)copy SMILES
Affinity DataIC50: 2.81E+3nMAssay Description:Binding affinity to signal peptide of human CD4-YFP expressed in CHO-K1 cells assessed down-modulation of CD4 surface expression incubated for 24 hrs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T3ZPubMed
TargetT-cell surface glycoprotein CD4(Homo sapiens (Human))TBA
LigandPNGBDBM50548970(CHEMBL4750160)copy SMILES
Affinity DataIC50: 9.30E+3nMAssay Description:Binding affinity to signal peptide of human CD4-YFP expressed in CHO-K1 cells assessed down-modulation of CD4 surface expression incubated for 24 hrs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7T3ZPubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Tibotec BVBA

Curated by ChEMBL
LigandPNGBDBM50204832(4-(2-(5-bromo-2-fluorophenyl)pteridin-4-ylamino)-N...)copy SMILEScopy InChI
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2999PubMed