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Found 132 with Last Name = 'volcho' and Initial = 'k'
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50589478(CHEMBL5187480)copy SMILES
Affinity DataIC50: 16nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833WZKPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50463376(CHEMBL4244758)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6FVMPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50507151(CHEMBL4438274)copy SMILEScopy InChI
Affinity DataIC50: 26nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833WZKPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50507151(CHEMBL4438274)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21 (DE3) using 5'-(5,6 FAM-aac gtc agg gtc ttc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56P1FPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50507140(CHEMBL4440514)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21 (DE3) using 5'-(5,6 FAM-aac gtc agg gtc ttc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56P1FPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50463381(CHEMBL4241424)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6FVMPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50463368(CHEMBL4250901)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6FVMPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50507150(CHEMBL4440114)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21 (DE3) using 5'-(5,6 FAM-aac gtc agg gtc ttc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56P1FPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50463384(CHEMBL4242066)copy SMILEScopy InChI
Affinity DataIC50: 81nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6FVMPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50507155(CHEMBL4587610)copy SMILEScopy InChI
Affinity DataIC50: 86nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21 (DE3) using 5'-(5,6 FAM-aac gtc agg gtc ttc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56P1FPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50540219(CHEMBL4642359)copy SMILEScopy InChI
Affinity DataIC50: 99nMAssay Description:Inhibition of TDP1 (unknown origin) using 5'-(5,6 FAM-AAC GTC AGG GTC TTC C- BHQ1)-3' as substrate measured for every 1 min by fluorescence based ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72N03PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM11995(2-chloro-5-(2,5-dimethyl-1H-pyrrol-1-yl)benzoic ac...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of Tdp1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56P1FPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50463372(CHEMBL3356739)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6FVMPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50507156(CHEMBL4475772)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21 (DE3) using 5'-(5,6 FAM-aac gtc agg gtc ttc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56P1FPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50507139(CHEMBL4446104)copy SMILEScopy InChI
Affinity DataIC50: 158nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21 (DE3) using 5'-(5,6 FAM-aac gtc agg gtc ttc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56P1FPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50463379(CHEMBL4243917)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6FVMPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50507153(CHEMBL4551119)copy SMILEScopy InChI
Affinity DataIC50: 172nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21 (DE3) using 5'-(5,6 FAM-aac gtc agg gtc ttc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56P1FPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50507152(CHEMBL4436400)copy SMILEScopy InChI
Affinity DataIC50: 192nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21 (DE3) using 5'-(5,6 FAM-aac gtc agg gtc ttc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56P1FPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50067508(CHEMBL3401896)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) assessed as increase in fluorescenceMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1NMKPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50463373(CHEMBL4250945)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6FVMPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50463364(CHEMBL4249351)copy SMILEScopy InChI
Affinity DataIC50: 232nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6FVMPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50540222(CHEMBL4643271)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Inhibition of TDP1 (unknown origin) using 5'-(5,6 FAM-AAC GTC AGG GTC TTC C- BHQ1)-3' as substrate measured for every 1 min by fluorescence based ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72N03PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50540220(CHEMBL4643649)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of TDP1 (unknown origin) using 5'-(5,6 FAM-AAC GTC AGG GTC TTC C- BHQ1)-3' as substrate measured for every 1 min by fluorescence based ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72N03PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50463386(CHEMBL4242317)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6FVMPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50463365(CHEMBL4251391)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6FVMPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50540221(CHEMBL4648584)copy SMILEScopy InChI
Affinity DataIC50: 360nMAssay Description:Inhibition of TDP1 (unknown origin) using 5'-(5,6 FAM-AAC GTC AGG GTC TTC C- BHQ1)-3' as substrate measured for every 1 min by fluorescence based ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72N03PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM81347(L2037 (beta-lapachone))copy SMILEScopy InChI
Affinity DataIC50: 360nMAssay Description:Inhibition of recombinant human Tdp1 using 5'-biotin-GATCTAAAAGACTT-pY-3' as substrate measured after 20 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56P1FPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50463374(CHEMBL3356738)copy SMILEScopy InChI
Affinity DataIC50: 390nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6FVMPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50463370(CHEMBL3356741)copy SMILEScopy InChI
Affinity DataIC50: 450nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6FVMPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50507154(CHEMBL4533174)copy SMILEScopy InChI
Affinity DataIC50: 457nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21 (DE3) using 5'-(5,6 FAM-aac gtc agg gtc ttc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56P1FPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50463369(CHEMBL4240521)copy SMILEScopy InChI
Affinity DataIC50: 530nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6FVMPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50463388(CHEMBL4240984)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6FVMPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50507148(CHEMBL4455616)copy SMILEScopy InChI
Affinity DataIC50: 610nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21 (DE3) using 5'-(5,6 FAM-aac gtc agg gtc ttc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56P1FPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50463363(CHEMBL4237246)copy SMILEScopy InChI
Affinity DataIC50: 630nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6FVMPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50463369(CHEMBL4240521)copy SMILEScopy InChI
Affinity DataIC50: 640nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-([32P]-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured after 20 mins by electrophoresis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6FVMPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50197097(CHEMBL3909527)copy SMILEScopy InChI
Affinity DataIC50: 675nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-AAC GTC AGG GTC TTC C-BHQ1)-3' as substrate measured every 1 min by fluorescence an...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6SGKPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50463360(CHEMBL4237606)copy SMILEScopy InChI
Affinity DataIC50: 720nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6FVMPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50463387(CHEMBL3356740)copy SMILEScopy InChI
Affinity DataIC50: 810nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6FVMPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50463362(CHEMBL4237693)copy SMILEScopy InChI
Affinity DataIC50: 840nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6FVMPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50540225(CHEMBL4637317)copy SMILEScopy InChI
Affinity DataIC50: 850nMAssay Description:Inhibition of TDP1 (unknown origin) using 5'-(5,6 FAM-AAC GTC AGG GTC TTC C- BHQ1)-3' as substrate measured for every 1 min by fluorescence based ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72N03PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50463377(CHEMBL4238219)copy SMILEScopy InChI
Affinity DataIC50: 860nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6FVMPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50397314(CHEMBL2170127)copy SMILEScopy InChI
Affinity DataIC50: 870nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833WZKPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50463367(CHEMBL4247712)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6FVMPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50540228(CHEMBL4636462)copy SMILEScopy InChI
Affinity DataIC50: 980nMAssay Description:Inhibition of TDP1 (unknown origin) using 5'-(5,6 FAM-AAC GTC AGG GTC TTC C- BHQ1)-3' as substrate measured for every 1 min by fluorescence based ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72N03PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50463385(CHEMBL4241774)copy SMILEScopy InChI
Affinity DataIC50: 980nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6FVMPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50388602(FURAMIDINE)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56P1FPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50507143(CHEMBL4570018)copy SMILEScopy InChI
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of Tdp1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56P1FPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50463375(CHEMBL4243326)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6FVMPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50540224(CHEMBL4633420)copy SMILEScopy InChI
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of TDP1 (unknown origin) using 5'-(5,6 FAM-AAC GTC AGG GTC TTC C- BHQ1)-3' as substrate measured for every 1 min by fluorescence based ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72N03PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50507141(CHEMBL4457603)copy SMILEScopy InChI
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56P1FPubMed
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