Compile Data Set for Download or QSAR
Found 78 with Last Name = 'welzenbach' and Initial = 'k'
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50161080((S)-2-[(S)-3-Isobutyl-2,5-dioxo-4-((E)-3-pyridin-4...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z72S2PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145392((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of HUT78 cell adhesion to immobilized ICAM-1 proteinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58KT2PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145391((1S,3R,8AS)-8-(2-{(4S,6S)-3-(4-HYDROXY-3-METHOXYBE...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50161067((2R)-2-[3-ISOBUTYL-2,5-DIOXO-4-(QUINOLIN-3-YLMETHY...)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50123241((S)-2-[(3S,5R)-3-Isobutyl-5-methyl-2-oxo-4-(2-quin...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of LFA-1/ICAM-1 interaction in ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K49K4PubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50123241((S)-2-[(3S,5R)-3-Isobutyl-5-methyl-2-oxo-4-(2-quin...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z72S2PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50123239((S)-2-[(3S,5R)-3-Isobutyl-5-methyl-2-oxo-4-(2-quin...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of LFA-1/ICAM-1 interaction in ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K49K4PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145392((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58KT2PubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50161072((S)-2-((S)-3-Isobutyl-2,5-dioxo-4-quinolin-6-yl-[1...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z72S2PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145394((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-(...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of HUT78 cell adhesion to immobilized ICAM-1 proteinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58KT2PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145391((1S,3R,8AS)-8-(2-{(4S,6S)-3-(4-HYDROXY-3-METHOXYBE...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145395((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Inhibition of HUT78 cell adhesion to immobilized ICAM-1 proteinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58KT2PubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50161065((S)-2-((R)-3-Isobutyl-2,5-dioxo-4-quinolin-3-ylmet...)copy SMILEScopy InChI
Affinity DataIC50: 510nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z72S2PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145396((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-3,7-di...)copy SMILEScopy InChI
Affinity DataIC50: 620nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58KT2PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145390((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-(2-{...)copy SMILEScopy InChI
Affinity DataIC50: 640nMAssay Description:Inhibition of HUT78 cell adhesion to immobilized ICAM-1 proteinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58KT2PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145388((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)copy SMILEScopy InChI
Affinity DataIC50: 680nMAssay Description:Inhibition of HUT78 cell adhesion to immobilized ICAM-1 proteinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58KT2PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50123244((S)-2-((3S,5R)-3-Isobutyl-5-methyl-2-oxo-4-phenyla...)copy SMILEScopy InChI
Affinity DataIC50: 750nMAssay Description:Inhibition of LFA-1/ICAM-1 interaction in ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K49K4PubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50161071((S)-2-[(S)-4-(4-Dimethylamino-benzyl)-3-isobutyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z72S2PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145398((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-(2-{...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58KT2PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145385(4-((1R,5R)-6-{2-[(1S,2S,6R,8S,8aR)-2,6-Dimethyl-8-...)copy SMILEScopy InChI
Affinity DataIC50: 870nMAssay Description:Inhibition of HUT78 cell adhesion to immobilized ICAM-1 proteinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58KT2PubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50161076((S)-2-[(S)-3-Isobutyl-4-(3-methyl-quinolin-5-ylmet...)copy SMILEScopy InChI
Affinity DataIC50: 890nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z72S2PubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50161082((S)-2-[(S)-4-(4-Hydroxy-3-methoxy-benzyl)-3-isobut...)copy SMILEScopy InChI
Affinity DataIC50: 950nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z72S2PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50123237((S)-2-[(3S,5R)-3-Isobutyl-5-methyl-2-oxo-4-(2-pyri...)copy SMILEScopy InChI
Affinity DataIC50: 970nMAssay Description:Inhibition of LFA-1/ICAM-1 interaction in ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K49K4PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145397((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-(...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58KT2PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145386((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)copy SMILEScopy InChI
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of HUT78 cell adhesion to immobilized ICAM-1 proteinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58KT2PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145393((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58KT2PubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50161078((S)-2-[(S)-4-(3-Hydroxy-benzyl)-3-isobutyl-2,5-dio...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z72S2PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50123242((S)-2-{(3S,5R)-4-[2-(4-Bromo-phenyl)-acetyl]-3-iso...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of LFA-1/ICAM-1 interaction in ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K49K4PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145399((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-(2-{...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58KT2PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50123240((S)-2-[(3S,5R)-3-Isobutyl-5-methyl-4-(2-naphthalen...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of LFA-1/ICAM-1 interaction in ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K49K4PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145397((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-(...)copy SMILEScopy InChI
Affinity DataIC50: 2.59E+3nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58KT2PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50123245((S)-2-[(3S,5R)-3-Isobutyl-5-methyl-2-oxo-4-(2-quin...)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of LFA-1/ICAM-1 interaction in ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K49K4PubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50161068((S)-2-((S)-4-Benzyl-3-isobutyl-2,5-dioxo-[1,4]diaz...)copy SMILEScopy InChI
Affinity DataIC50: 2.85E+3nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z72S2PubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50161075((S)-2-[(S)-4-(4-Bromo-cyclohexa-1,3-dienylmethyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 2.95E+3nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z72S2PubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50161069((S)-2-[(S)-4-(4-Bromo-benzyl)-3-isobutyl-2,5-dioxo...)copy SMILEScopy InChI
Affinity DataIC50: 2.95E+3nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z72S2PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145387((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-(2-{...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58KT2PubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50161073((S)-2-[(S)-3-Isobutyl-2,5-dioxo-4-(pyridin-4-ylcar...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z72S2PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50004774((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-(...)copy SMILEScopy InChI
Affinity DataIC50: 3.78E+3nMAssay Description:Inhibition of HUT78 cell adhesion to immobilized ICAM-1 proteinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58KT2PubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50161070((R)-2-((R)-3-Isobutyl-2,5-dioxo-4-quinolin-3-ylmet...)copy SMILEScopy InChI
Affinity DataIC50: 4.20E+3nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z72S2PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145388((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of HUT78 cell adhesion to immobilized ICAM-1 proteinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58KT2PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145386((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)copy SMILEScopy InChI
Affinity DataIC50: 5.59E+3nMAssay Description:Inhibition of HUT78 cell adhesion to immobilized ICAM-1 proteinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58KT2PubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50161074((R)-2-((S)-3-Isobutyl-2,5-dioxo-4-quinolin-3-ylmet...)copy SMILEScopy InChI
Affinity DataIC50: 5.70E+3nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z72S2PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145394((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-(...)copy SMILEScopy InChI
Affinity DataIC50: 6.42E+3nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58KT2PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145395((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)copy SMILEScopy InChI
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of HUT78 cell adhesion to immobilized ICAM-1 proteinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58KT2PubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50161077((S)-2-[(S)-4-(3-Benzyloxy-benzyl)-3-isobutyl-2,5-d...)copy SMILEScopy InChI
Affinity DataIC50: 6.60E+3nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z72S2PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145387((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-(2-{...)copy SMILEScopy InChI
Affinity DataIC50: 7.69E+3nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58KT2PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145398((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-(2-{...)copy SMILEScopy InChI
Affinity DataIC50: 9.50E+3nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58KT2PubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50161066((S)-2-[(S)-3-Isobutyl-2,5-dioxo-4-(4-pyridin-3-yl-...)copy SMILEScopy InChI
Affinity DataIC50: 1.33E+4nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z72S2PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50123238((S)-2-[(S)-3-Isobutyl-5-methyl-4-(2-naphthalen-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of LFA-1/ICAM-1 interaction in ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K49K4PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50123243((S)-2-[(3S,5R)-3-Isobutyl-5-methyl-4-(2-naphthalen...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of LFA-1/ICAM-1 interaction in ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K49K4PubMed
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