Compile Data Set for Download or QSAR
Found 859 with Last Name = 'bollinger' and Initial = 'ka'
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50577263(CHEMBL4850236)copy SMILES
Affinity DataKi:  17nMAssay Description:Inhibition of human sigma1 receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B92V4PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50577261(CHEMBL4849905)copy SMILES
Affinity DataKi:  120nMAssay Description:Displacement of [3H]NMS from human acetyl cholinesterase receptor expressed in CHO cell membranes incubated for 3 hrs by radiometric scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B92V4PubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283472(CHEMBL4160748)copy SMILEScopy InChI
Affinity DataKi:  650nMAssay Description:Displacement of [3H] substance P from recombinant human NK1 receptor expressed in CHO cells after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85BN1PubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))TBA
LigandPNGBDBM50577264(CHEMBL4873386)copy SMILES
Affinity DataIC50: 0.427nMAssay Description:Antagonist activity at human muscarinic acetylcholine M4 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B92V4PubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))TBA
LigandPNGBDBM50577264(CHEMBL4873386)copy SMILES
Affinity DataIC50: 0.430nMAssay Description:Antagonist activity at human muscarinic acetylcholine M4 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B92V4PubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))TBA
LigandPNGBDBM50577262(CHEMBL4853244)copy SMILES
Affinity DataIC50: 0.440nMAssay Description:Displacement of [3H]NMS from human muscarinic receptor M4 expressed in CHO cell membranes incubated for 3 hrs by radiometric scintillation counting a...More data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B92V4PubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))TBA
LigandPNGBDBM50577264(CHEMBL4873386)copy SMILES
Affinity DataIC50: 0.589nMAssay Description:Antagonist activity at human muscarinic acetylcholine M4 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B92V4PubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))TBA
LigandPNGBDBM50577264(CHEMBL4873386)copy SMILES
Affinity DataIC50: 0.590nMAssay Description:Antagonist activity at human muscarinic acetylcholine M4 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B92V4PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN 37232, USA; Department of Pharmacology, Vanderbilt University, Nashville, TN 37232, USA.

Curated by ChEMBL
LigandPNGBDBM22165(1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 0.710nMAssay Description:Displacement of [125I]RTI-55 from recombinant human DAT expressed in CHOK1 cells after 3 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V1278ZPubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))TBA
LigandPNGBDBM50577267(CHEMBL4855467)copy SMILES
Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at human muscarinic acetylcholine M4 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B92V4PubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))TBA
LigandPNGBDBM50577267(CHEMBL4855467)copy SMILES
Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at human muscarinic acetylcholine M4 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B92V4PubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))TBA
LigandPNGBDBM50577268(CHEMBL4851711)copy SMILES
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity at human muscarinic acetylcholine M4 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B92V4PubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))TBA
LigandPNGBDBM50577271(CHEMBL4864914)copy SMILES
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity at human muscarinic acetylcholine M4 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B92V4PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50577268(CHEMBL4851711)copy SMILES
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity at human muscarinic acetylcholine M4 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B92V4PubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))TBA
LigandPNGBDBM50577271(CHEMBL4864914)copy SMILES
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity at human muscarinic acetylcholine M4 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B92V4PubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))TBA
LigandPNGBDBM50577269(CHEMBL4854289)copy SMILES
Affinity DataIC50: 2.30nMAssay Description:Antagonist activity at human muscarinic acetylcholine M4 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B92V4PubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))TBA
LigandPNGBDBM50577269(CHEMBL4854289)copy SMILES
Affinity DataIC50: 2.30nMAssay Description:Antagonist activity at human muscarinic acetylcholine M4 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B92V4PubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))TBA
LigandPNGBDBM50577265(CHEMBL4876599)copy SMILES
Affinity DataIC50: 2.80nMAssay Description:Antagonist activity at human muscarinic acetylcholine M4 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B92V4PubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))TBA
LigandPNGBDBM50577265(CHEMBL4876599)copy SMILES
Affinity DataIC50: 2.80nMAssay Description:Antagonist activity at human muscarinic acetylcholine M4 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B92V4PubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))TBA
LigandPNGBDBM50577263(CHEMBL4850236)copy SMILES
Affinity DataIC50: 4.10nMAssay Description:Antagonist activity at human muscarinic acetylcholine M4 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B92V4PubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))TBA
LigandPNGBDBM50577263(CHEMBL4850236)copy SMILES
Affinity DataIC50: 4.10nMAssay Description:Antagonist activity at human muscarinic acetylcholine M4 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B92V4PubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))TBA
LigandPNGBDBM50577263(CHEMBL4850236)copy SMILES
Affinity DataIC50: 4.5nMAssay Description:Antagonist activity at human muscarinic acetylcholine M4 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B92V4PubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))TBA
LigandPNGBDBM50577263(CHEMBL4850236)copy SMILES
Affinity DataIC50: 4.5nMAssay Description:Antagonist activity at human muscarinic acetylcholine M4 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B92V4PubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))TBA
LigandPNGBDBM50577266(CHEMBL4848896)copy SMILES
Affinity DataIC50: 5.20nMAssay Description:Antagonist activity at human muscarinic acetylcholine M4 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B92V4PubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))TBA
LigandPNGBDBM50577266(CHEMBL4848896)copy SMILES
Affinity DataIC50: 5.20nMAssay Description:Antagonist activity at human muscarinic acetylcholine M4 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B92V4PubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))TBA
LigandPNGBDBM50577272(CHEMBL4865665)copy SMILES
Affinity DataIC50: 7.80nMAssay Description:Antagonist activity at human muscarinic acetylcholine M4 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B92V4PubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))TBA
LigandPNGBDBM50577270(CHEMBL4860985)copy SMILES
Affinity DataIC50: 7.80nMAssay Description:Antagonist activity at human muscarinic acetylcholine M4 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B92V4PubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))TBA
LigandPNGBDBM50577270(CHEMBL4860985)copy SMILES
Affinity DataIC50: 7.80nMAssay Description:Antagonist activity at human muscarinic acetylcholine M4 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B92V4PubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))TBA
LigandPNGBDBM50577272(CHEMBL4865665)copy SMILES
Affinity DataIC50: 7.80nMAssay Description:Antagonist activity at human muscarinic acetylcholine M4 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B92V4PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN 37232, USA; Department of Pharmacology, Vanderbilt University, Nashville, TN 37232, USA.

Curated by ChEMBL
LigandPNGBDBM50005548((+)-2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinol...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of full-length recombinant human DAT expressed in CHOK1 cells assessed as reduction in [3H]dopamine uptake pretreated for 20 mins followed...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V1278ZPubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN 37232, USA; Department of Pharmacology, Vanderbilt University, Nashville, TN 37232, USA.

Curated by ChEMBL
LigandPNGBDBM50262571(CHEMBL4066902)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Negative allosteric modulation of rat mGlu5 receptor expressed in HEK293 cells assessed as inhibition of glutamate induced-calcium mobilization prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V1278ZPubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN 37232, USA; Department of Pharmacology, Vanderbilt University, Nashville, TN 37232, USA.

Curated by ChEMBL
LigandPNGBDBM50262571(CHEMBL4066902)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Negative allosteric modulation of rat mGlu5 receptor expressed in HEK293 cells assessed as inhibition of glutamate induced-calcium mobilization prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V1278ZPubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN 37232, USA; Department of Pharmacology, Vanderbilt University, Nashville, TN 37232, USA.

Curated by ChEMBL
LigandPNGBDBM50262573(CHEMBL4089114)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Negative allosteric modulation of rat mGlu5 receptor expressed in HEK293 cells assessed as inhibition of glutamate induced-calcium mobilization prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V1278ZPubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN 37232, USA; Department of Pharmacology, Vanderbilt University, Nashville, TN 37232, USA.

Curated by ChEMBL
LigandPNGBDBM50262573(CHEMBL4089114)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Negative allosteric modulation of rat mGlu5 receptor expressed in HEK293 cells assessed as inhibition of glutamate induced-calcium mobilization prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V1278ZPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50503552(CHEMBL4446070)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Negative allosteric modulation of human mGlu5 receptor assessed as inhibition of glutamate induced-calcium mobilizationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2MF6PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN 37232, USA; Department of Pharmacology, Vanderbilt University, Nashville, TN 37232, USA.

Curated by ChEMBL
LigandPNGBDBM50262608(CHEMBL4071447)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Negative allosteric modulation of rat mGlu5 receptor expressed in HEK293 cells assessed as inhibition of glutamate induced-calcium mobilization prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V1278ZPubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN 37232, USA; Department of Pharmacology, Vanderbilt University, Nashville, TN 37232, USA.

Curated by ChEMBL
LigandPNGBDBM50262608(CHEMBL4071447)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Negative allosteric modulation of rat mGlu5 receptor expressed in HEK293 cells assessed as inhibition of glutamate induced-calcium mobilization prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V1278ZPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50503571(CHEMBL4563956)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Negative allosteric modulation of human mGlu5 receptor assessed as inhibition of glutamate induced-calcium mobilizationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2MF6PubMed
TargetMetabotropic glutamate receptor 2(Rattus norvegicus)
Vanderbilt University

US Patent
LigandPNGBDBM430158(4-(2-fluoro-4-methoxyphenyl)-5-((2-methylpyridin-4...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Gα15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5QKFUS Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50503566(CHEMBL4458831)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Negative allosteric modulation of human mGlu5 receptor assessed as inhibition of glutamate induced-calcium mobilizationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2MF6PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50503577(CHEMBL4540550)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Negative allosteric modulation of human mGlu5 receptor assessed as inhibition of glutamate induced-calcium mobilizationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2MF6PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN 37232, USA; Department of Pharmacology, Vanderbilt University, Nashville, TN 37232, USA.

Curated by ChEMBL
LigandPNGBDBM50262633(CHEMBL4077770)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Negative allosteric modulation of rat mGlu5 receptor expressed in HEK293 cells assessed as inhibition of glutamate induced-calcium mobilization prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V1278ZPubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN 37232, USA; Department of Pharmacology, Vanderbilt University, Nashville, TN 37232, USA.

Curated by ChEMBL
LigandPNGBDBM50262633(CHEMBL4077770)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Negative allosteric modulation of rat mGlu5 receptor expressed in HEK293 cells assessed as inhibition of glutamate induced-calcium mobilization prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V1278ZPubMed
TargetMetabotropic glutamate receptor 2(Rattus norvegicus)
Vanderbilt University

US Patent
LigandPNGBDBM430113(4-(2-fluoro-4-methoxyphenyl)-5-(pyridin-3-ylmethox...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Gα15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5QKFUS Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN 37232, USA; Department of Pharmacology, Vanderbilt University, Nashville, TN 37232, USA.

Curated by ChEMBL
LigandPNGBDBM50262623(CHEMBL4092008)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Negative allosteric modulation of rat mGlu5 receptor expressed in HEK293 cells assessed as inhibition of glutamate induced-calcium mobilization prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V1278ZPubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN 37232, USA; Department of Pharmacology, Vanderbilt University, Nashville, TN 37232, USA.

Curated by ChEMBL
LigandPNGBDBM50262623(CHEMBL4092008)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Negative allosteric modulation of rat mGlu5 receptor expressed in HEK293 cells assessed as inhibition of glutamate induced-calcium mobilization prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V1278ZPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50503553(CHEMBL4569680)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Negative allosteric modulation of human mGlu5 receptor assessed as inhibition of glutamate induced-calcium mobilizationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2MF6PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN 37232, USA; Department of Pharmacology, Vanderbilt University, Nashville, TN 37232, USA.

Curated by ChEMBL
LigandPNGBDBM50262576(CHEMBL4089606)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Negative allosteric modulation of rat mGlu5 receptor expressed in HEK293 cells assessed as inhibition of glutamate induced-calcium mobilization prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V1278ZPubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN 37232, USA; Department of Pharmacology, Vanderbilt University, Nashville, TN 37232, USA.

Curated by ChEMBL
LigandPNGBDBM50262576(CHEMBL4089606)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Negative allosteric modulation of rat mGlu5 receptor expressed in HEK293 cells assessed as inhibition of glutamate induced-calcium mobilization prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V1278ZPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50503538(CHEMBL4569447)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Negative allosteric modulation of human mGlu5 receptor assessed as inhibition of glutamate induced-calcium mobilizationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2MF6PubMed
Displayed 1 to 50 (of 859 total ) | Next | Last >>
Jump to: