Compile Data Set for Download or QSAR
Found 314 with Last Name = 'maegley' and Initial = 'ka'
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50246967(CHEMBL4080228 | US10570121, Example 81)copy SMILEScopy InChI
Affinity DataKi: <0.100nMAssay Description:Binding affinity to EZH2 (unknown origin)More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50193709(CHEMBL3911017)copy SMILEScopy InChI
Affinity DataKi:  0.700nMAssay Description:Inhibition of wild-type EZH2 (unknown origin) expressed in baculovirus infected SF9 cells co-expressing SUZ12/EED/RbAp48 complex using HeLa cells der...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50193663(CHEMBL3929944)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of wild-type EZH2 (unknown origin) expressed in baculovirus infected SF9 cells co-expressing SUZ12/EED/RbAp48 complex using HeLa cells der...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J1053BPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50145214(2-(4-((methylamino)methyl)phenyl)-1H-benzo[d]imida...)copy SMILEScopy InChI
Affinity DataKi:  3.20nMAssay Description:Binding affinity towards human poly(ADP-ribose) polymerase-1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N1MPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50154756(6-(4-Methylaminomethyl-phenyl)-3,4-dihydro-2H-[1,4...)copy SMILEScopy InChI
Affinity DataKi:  3.80nMAssay Description:Inhibition of human Poly (ADP-ribose) polymerase 1 enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FM4PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50122777(1-Phenyl-8,9-dihydro-7H-2,7,9a-triaza-benzo[cd]azu...)copy SMILEScopy InChI
Affinity DataKi:  4.10nMAssay Description:Inhibitory activity of the compound against human full length Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154GDBPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50122775(1-(4-Hydroxymethyl-phenyl)-8,9-dihydro-7H-2,7,9a-t...)copy SMILEScopy InChI
Affinity DataKi:  4.20nMAssay Description:Inhibitory activity of the compound against human full length Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154GDBPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50145216(2-(4-{[Bis-(2-hydroxy-ethyl)-amino]-methyl}-phenyl...)copy SMILEScopy InChI
Affinity DataKi:  4.5nMAssay Description:Binding affinity towards human poly(ADP-ribose) polymerase-1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N1MPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50145224(2-(4-Dimethylaminomethyl-phenyl)-1H-benzoimidazole...)copy SMILEScopy InChI
Affinity DataKi:  4.5nMAssay Description:Binding affinity towards human poly(ADP-ribose) polymerase-1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N1MPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50122781(1-Naphthalen-1-yl-8,9-dihydro-7H-2,7,9a-triaza-ben...)copy SMILEScopy InChI
Affinity DataKi:  4.90nMAssay Description:Inhibitory activity of the compound against human full length Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154GDBPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50120704(2-Naphthalen-1-yl-1,3,4,5-tetrahydro-azepino[5,4,3...)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:In vitro inhibitory activity towards human poly(ADP-ribose) polymerase 1 (PARP-1).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152ZPPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM27685(2-{4-[(dimethylamino)methyl]phenyl}-3,10-diazatric...)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:In vitro inhibitory activity towards human poly(ADP-ribose) polymerase 1 (PARP-1).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152ZPPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50120702(2-(4-Trifluoromethyl-phenyl)-1,3,4,5-tetrahydro-az...)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:In vitro inhibitory activity towards human poly(ADP-ribose) polymerase 1 (PARP-1).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152ZPPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50120707(2-Thiophen-2-yl-1,3,4,5-tetrahydro-azepino[5,4,3-c...)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:In vitro inhibitory activity towards human poly(ADP-ribose) polymerase 1 (PARP-1).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152ZPPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50145223(2-(3-Dimethylaminomethyl-phenyl)-1H-benzoimidazole...)copy SMILEScopy InChI
Affinity DataKi:  5.60nMAssay Description:Binding affinity towards human poly(ADP-ribose) polymerase-1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N1MPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50122779(1-(4-Chloro-phenyl)-8,9-dihydro-7H-2,7,9a-triaza-b...)copy SMILEScopy InChI
Affinity DataKi:  5.70nMAssay Description:Inhibitory activity of the compound against human full length Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154GDBPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50122776(1-(4-Dimethylaminomethyl-phenyl)-8,9-dihydro-7H-2,...)copy SMILEScopy InChI
Affinity DataKi:  5.80nMAssay Description:Inhibitory activity of the compound against human full length Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154GDBPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50145225(2-(4-Pyrrolidin-1-ylmethyl-phenyl)-1H-benzoimidazo...)copy SMILEScopy InChI
Affinity DataKi:  5.90nMAssay Description:Binding affinity towards human poly(ADP-ribose) polymerase-1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N1MPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50145221(2-{4-[(4-Methoxy-benzyl)-methyl-amino]-phenyl}-1H-...)copy SMILEScopy InChI
Affinity DataKi:  5.90nMAssay Description:Binding affinity towards human poly(ADP-ribose) polymerase-1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N1MPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50093374(2-(4-Hydroxy-phenyl)-1H-benzoimidazole-4-carboxyli...)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:Inhibition of human Poly (ADP-ribose) polymerase 1 enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FM4PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50154726(6-(4-Fluoro-phenyl)-1-oxo-1,2,3,4-tetrahydro-[1,4]...)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:Inhibition of human Poly (ADP-ribose) polymerase 1 enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FM4PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50120724(2-Phenyl-1,3,4,5-tetrahydro-azepino[5,4,3-cd]indol...)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:In vitro inhibitory activity towards human poly(ADP-ribose) polymerase 1 (PARP-1).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152ZPPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50120726(2-(3-Trifluoromethyl-phenyl)-1,3,4,5-tetrahydro-az...)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:In vitro inhibitory activity towards human poly(ADP-ribose) polymerase 1 (PARP-1).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152ZPPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50120706(2-(4-Pyrrol-1-ylmethyl-phenyl)-1,3,4,5-tetrahydro-...)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:In vitro inhibitory activity of the compound towards human Poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152ZPPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50120728(2-(4-Methoxy-phenyl)-1,3,4,5-tetrahydro-azepino[5,...)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:In vitro inhibitory activity towards human poly(ADP-ribose) polymerase 1 (PARP-1).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152ZPPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50122772(1-(3-Dimethylaminomethyl-phenyl)-8,9-dihydro-7H-2,...)copy SMILEScopy InChI
Affinity DataKi:  6.30nMAssay Description:Inhibitory activity of the compound against human full length Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154GDBPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50154730(6-(4-((dimethylamino)methyl)phenyl)-3,4-dihydro-[1...)copy SMILEScopy InChI
Affinity DataKi:  6.40nMAssay Description:Inhibition of human Poly (ADP-ribose) polymerase 1 enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FM4PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50154750(6-(4-Pyrrol-1-ylmethyl-phenyl)-3,4-dihydro-2H-[1,4...)copy SMILEScopy InChI
Affinity DataKi:  6.80nMAssay Description:Inhibition of human Poly (ADP-ribose) polymerase 1 enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FM4PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50154728(6-(3-Methylaminomethyl-phenyl)-3,4-dihydro-2H-[1,4...)copy SMILEScopy InChI
Affinity DataKi:  6.90nMAssay Description:Inhibition of human Poly (ADP-ribose) polymerase 1 enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FM4PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50120710(2-(3-Amino-phenyl)-1,3,4,5-tetrahydro-azepino[5,4,...)copy SMILEScopy InChI
Affinity DataKi:  7nMAssay Description:In vitro inhibitory activity towards human poly(ADP-ribose) polymerase 1 (PARP-1).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152ZPPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50120718(2-Pyridin-3-yl-1,3,4,5-tetrahydro-azepino[5,4,3-cd...)copy SMILEScopy InChI
Affinity DataKi:  7nMAssay Description:In vitro inhibitory activity towards human poly(ADP-ribose) polymerase 1 (PARP-1).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152ZPPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50120721(1-Methyl-2-phenyl-1,3,4,5-tetrahydro-azepino[5,4,3...)copy SMILEScopy InChI
Affinity DataKi:  7nMAssay Description:In vitro inhibitory activity towards human poly(ADP-ribose) polymerase 1 (PARP-1).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152ZPPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50145219(2-(4-Piperidin-1-ylmethyl-phenyl)-1H-benzoimidazol...)copy SMILEScopy InChI
Affinity DataKi:  7.20nMAssay Description:Binding affinity towards human poly(ADP-ribose) polymerase-1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N1MPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50154739(6-(4-Chloro-phenyl)-1-oxo-1,2,3,4-tetrahydro-[1,4]...)copy SMILEScopy InChI
Affinity DataKi:  7.5nMAssay Description:Inhibition of human Poly (ADP-ribose) polymerase 1 enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FM4PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50122774(1-(2-Chloro-phenyl)-8,9-dihydro-7H-2,7,9a-triaza-b...)copy SMILEScopy InChI
Affinity DataKi:  7.70nMAssay Description:Inhibitory activity of the compound against human full length Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154GDBPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50120720(2-(2-Chloro-phenyl)-1,3,4,5-tetrahydro-azepino[5,4...)copy SMILEScopy InChI
Affinity DataKi:  8nMAssay Description:In vitro inhibitory activity towards human poly(ADP-ribose) polymerase 1 (PARP-1).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152ZPPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50120731(2-(1H-Pyrrol-2-yl)-1,3,4,5-tetrahydro-azepino[5,4,...)copy SMILEScopy InChI
Affinity DataKi:  8nMAssay Description:In vitro inhibitory activity towards human poly(ADP-ribose) polymerase 1 (PARP-1).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152ZPPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50120723(2-(3-Dimethylaminomethyl-phenyl)-1,3,4,5-tetrahydr...)copy SMILEScopy InChI
Affinity DataKi:  8nMAssay Description:In vitro inhibitory activity towards human poly(ADP-ribose) polymerase 1 (PARP-1).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152ZPPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50154741(6-(4-Methoxy-phenyl)-3,4-dihydro-2H-[1,4]diazepino...)copy SMILEScopy InChI
Affinity DataKi:  8.20nMAssay Description:Inhibition of human Poly (ADP-ribose) polymerase 1 enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FM4PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50145215(2-[4-(4-Methyl-piperazin-1-ylmethyl)-phenyl]-1H-be...)copy SMILEScopy InChI
Affinity DataKi:  8.70nMAssay Description:Binding affinity towards human poly(ADP-ribose) polymerase-1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N1MPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50122780(1-(3-Hydroxymethyl-phenyl)-8,9-dihydro-7H-2,7,9a-t...)copy SMILEScopy InChI
Affinity DataKi:  8.80nMAssay Description:Inhibitory activity of the compound against human full length Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154GDBPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50120722(2-(1H-Indol-5-yl)-1,3,4,5-tetrahydro-azepino[5,4,3...)copy SMILEScopy InChI
Affinity DataKi:  9nMAssay Description:In vitro inhibitory activity towards human poly(ADP-ribose) polymerase 1 (PARP-1).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152ZPPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50154759(6-(4-Fluoro-phenyl)-7-(1-hydroxyimino-ethyl)-3,4-d...)copy SMILEScopy InChI
Affinity DataKi:  9.10nMAssay Description:Inhibition of human Poly (ADP-ribose) polymerase 1 enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FM4PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50154740(6-(3-Dimethylaminomethyl-phenyl)-3,4-dihydro-2H-[1...)copy SMILEScopy InChI
Affinity DataKi:  9.10nMAssay Description:Inhibition of human Poly (ADP-ribose) polymerase 1 enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FM4PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50154735(1-Oxo-1,2,3,4-tetrahydro-[1,4]diazepino[6,7,1-hi]i...)copy SMILEScopy InChI
Affinity DataKi:  9.40nMAssay Description:Inhibition of human Poly (ADP-ribose) polymerase 1 enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FM4PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50145222(2-[3-(4-Methyl-piperazin-1-ylmethyl)-phenyl]-1H-be...)copy SMILEScopy InChI
Affinity DataKi:  9.80nMAssay Description:Binding affinity towards human poly(ADP-ribose) polymerase-1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N1MPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50120700(6-Oxo-3,4,5,6-tetrahydro-1H-azepino[5,4,3-cd]indol...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:In vitro inhibitory activity towards human poly(ADP-ribose) polymerase 1 (PARP-1).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152ZPPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50120712(2-Methoxy-1,3,4,5-tetrahydro-azepino[5,4,3-cd]indo...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:In vitro inhibitory activity towards human poly(ADP-ribose) polymerase 1 (PARP-1).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152ZPPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50145220(2-(3-Pyrrolidin-1-ylmethyl-phenyl)-1H-benzoimidazo...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Binding affinity towards human poly(ADP-ribose) polymerase-1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N1MPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50154729(6-(4-Chloro-phenyl)-3,4-dihydro-2H-[1,4]diazepino[...)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Inhibition of human Poly (ADP-ribose) polymerase 1 enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FM4PubMed
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