Compile Data Set for Download or QSAR
Found 94 with Last Name = 'silverman' and Initial = 'kc'
LigandPNGBDBM50287709((E)-3-Carboxy-2-(16-sulfooxy-hexadecyl)-pent-2-ene...)copy SMILEScopy InChI
Affinity DataKi:  4.5nMAssay Description:In vitro inhibition of human recombinant Protein farnesyltransferase with respect to FPPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222TQ1
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50292415(CHEMBL504845 | Zaragozic Acid B)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of rat liver squalene synthase by liqiud scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M908Q1PubMed
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50292333(CHEMBL505374 | zaragozic acid C)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of rat liver squalene synthase by liqiud scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M908Q1PubMed
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50051873((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of rat liver squalene synthase by liqiud scintillation countingMore data for this Ligand-Target Pair
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50292413(CHEMBL502210 | Zaragozic Acid D2)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of rat liver squalene synthase by liqiud scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M908Q1PubMed
LigandPNGBDBM50287707((E)-3-Carboxy-2-(16-hydroxy-hexadecyl)-pent-2-ened...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:In vitro inhibition of human recombinant Protein farnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222TQ1
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50292414(CHEMBL502872 | Zaragozic Acid D)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of rat liver squalene synthase by liqiud scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M908Q1PubMed
LigandPNGBDBM50287708((E)-3-Methoxycarbonyl-2-(16-sulfooxy-hexadecyl)-pe...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:In vitro inhibition of human recombinant Protein farnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222TQ1
LigandPNGBDBM50287709((E)-3-Carboxy-2-(16-sulfooxy-hexadecyl)-pent-2-ene...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:In vitro inhibition of human recombinant Protein farnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222TQ1
LigandPNGBDBM50067848((S)-2-(((3aR,6R,9S)-3a,6,9-trimethyl-3-(6-methylhe...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23779DQPubMed
LigandPNGBDBM50067843((S)-2-[(3aR,6R)-3-(1,5-Dimethyl-hexyl)-3a,6-dimeth...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of human FarnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23779DQPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123449(CHEMBL437996 | Chloropeptin II | ISOCOMPLESTATIN)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of HIV1 integrase 3' processing/strand transfer coupled activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N552NPubMed
LigandPNGBDBM50250718(2-alpha-(3'-hydroxy-3'-methylglutaroyl)-24,25-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibition of human Farnesyltransferase using Ras-CVLSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23779DQPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50366855(CHEMBL525803 | Chloropeptin)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of HIV1 integrase 3' processing/strand transfer coupled activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N552NPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123449(CHEMBL437996 | Chloropeptin II | ISOCOMPLESTATIN)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of disintegration activity of HIV1 integrase catalytic core domain (50 to 212)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N552NPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123449(CHEMBL437996 | Chloropeptin II | ISOCOMPLESTATIN)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of disintegration activity of HIV1 intact integraseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N552NPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478734(CHEMBL448564)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of HIV1 integrase 3' processing/strand transfer coupled activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N552NPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478738(CHEMBL507121)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibition of HIV1 integrase 3' processing/strand transfer coupled activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N552NPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478735(CHEBI:65655 | COMPLESTATINS A)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of HIV1 integrase 3' processing/strand transfer coupled activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N552NPubMed
LigandPNGBDBM50067852(3-[(3aR,6R,9S)-3-(1,5-Dimethyl-hexyl)-3a,6,9-trime...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23779DQPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124971((2R,3S)-5,6,8,5',6',8'-Hexahydroxy-2,3,2',3'-tetra...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of HIV-1 integrase in coupled transfer assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22R3R1HPubMed
LigandPNGBDBM50067842(2'',15''-dimethyl-5'',17''-dioxo-(2''R,5'R,15''S)-...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23779DQPubMed
LigandPNGBDBM50067825(3-[(R)-3-(1,5-Dimethyl-hexyl)-3a-methyl-7-oxo-dode...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23779DQPubMed
LigandPNGBDBM50250718(2-alpha-(3'-hydroxy-3'-methylglutaroyl)-24,25-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human Farnesyltransferase using Ras-CVIMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23779DQPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478740(CHEBI:65656 | COMPLESTATIN B)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of HIV1 integrase 3' processing/strand transfer coupled activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N552NPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124967(5,6,8,5',6',8'-Hexahydroxy-2,3,2',3'-tetramethyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of HIV-1 integrase in strand transfer assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22R3R1HPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124967(5,6,8,5',6',8'-Hexahydroxy-2,3,2',3'-tetramethyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of HIV-1 integrase in coupled transfer assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22R3R1HPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123449(CHEMBL437996 | Chloropeptin II | ISOCOMPLESTATIN)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of integration activity of HIV1 intact integraseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N552NPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124966((8R,9R)-2,4,5-Trihydroxy-8,9-dimethyl-1-((2S,3R)-5...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of HIV-1 integrase in coupled transfer assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22R3R1HPubMed
LigandPNGBDBM50067849((S)-2-[(3aR,6R,9S)-3-(1,5-Dimethyl-hexyl)-9-ethyl-...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23779DQPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478736(CHEMBL505739)copy SMILEScopy InChI
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of HIV1 integrase 3' processing/strand transfer coupled activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N552NPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123449(CHEMBL437996 | Chloropeptin II | ISOCOMPLESTATIN)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N552NPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124971((2R,3S)-5,6,8,5',6',8'-Hexahydroxy-2,3,2',3'-tetra...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of HIV-1 integrase in strand transfer assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22R3R1HPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50366855(CHEMBL525803 | Chloropeptin)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N552NPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478734(CHEMBL448564)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N552NPubMed
LigandPNGBDBM50067854(CHEMBL344638 | Isobutyric acid 2-((10R,13S)-10,13-...)copy SMILEScopy InChI
Affinity DataIC50: 6.80E+3nMAssay Description:inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23779DQPubMed
LigandPNGBDBM50071242(Acetic acid (6aR,6bS,9S,10aR,12aS)-5-hydroxy-1,3-d...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human recombinant farnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W958BGPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478739(CHEMBL448271)copy SMILEScopy InChI
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of HIV1 integrase 3' processing/strand transfer coupled activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N552NPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124964(6,8'-Dihydroxy-5,8,5',6'-tetramethoxy-2,3,2',3'-te...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of HIV-1 integrase in coupled transfer assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22R3R1HPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478738(CHEMBL507121)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N552NPubMed
LigandPNGBDBM50067834((3aR,6R)-6-(2-Carboxy-ethyl)-3-(1,5-dimethyl-hexyl...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23779DQPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124966((8R,9R)-2,4,5-Trihydroxy-8,9-dimethyl-1-((2S,3R)-5...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of HIV-1 integrase in strand transfer assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22R3R1HPubMed
LigandPNGBDBM50067835((10S,13R,14R)-17-(1,5-Dimethyl-hex-4-enyl)-4,4,10,...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23779DQPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124967(5,6,8,5',6',8'-Hexahydroxy-2,3,2',3'-tetramethyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of HIV-1 integrase in strand transfer assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22R3R1HPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478735(CHEBI:65655 | COMPLESTATINS A)copy SMILEScopy InChI
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N552NPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478740(CHEBI:65656 | COMPLESTATIN B)copy SMILEScopy InChI
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N552NPubMed
LigandPNGBDBM50071241(Acetic acid (6aR,6bS,9S,10aR,12aS)-5-hydroxy-6b,10...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human recombinant farnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W958BGPubMed
LigandPNGBDBM50455157(Cortisone | Cortisone acetate | Cortone)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMAssay Description:inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23779DQPubMed
LigandPNGBDBM50067846((2R,10S,13R,14R,17R)-17-((R)-4,5-Dihydroxy-1,5-dim...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23779DQPubMed
LigandPNGBDBM50067841(CHEMBL138291 | Isobutyric acid 2-((10R,13S,17R)-17...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23779DQPubMed
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