Compile Data Set for Download or QSAR
Found 26 with Last Name = 'lane' and Initial = 'kd'
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM35229(3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-met...)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMedDrugBank
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50010859(CHEMBL11 | IMIPRAMINE HYDROCHLORIDE | IMIPRAMINE P...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of [3H]5HT uptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM35229(3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-met...)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Inhibition of [3H]5HT uptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMedDrugBank
TargetHistamine H1 receptor(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM35938(1-(p-chlorophenyl)-1-(2-pyridyl)-3-N,N-dimethylpro...)copy SMILEScopy InChI
Affinity DataIC50: 66nMAssay Description:Displacement of [3H]pyrilamine from human histamine receptor subtype 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMedDrugBank
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50010859(CHEMBL11 | IMIPRAMINE HYDROCHLORIDE | IMIPRAMINE P...)copy SMILEScopy InChI
Affinity DataIC50: 74nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMedDrugBank
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of [3H]5HT uptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249783(10-(6-(diethylamino)hexyl)acridin-9(10H)-one | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of [3H]5HT uptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249783(10-(6-(diethylamino)hexyl)acridin-9(10H)-one | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Displacement of [3H]pyrilamine from human histamine receptor subtype 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249782(10-(5-(diethylamino)pentyl)acridin-9(10H)-one | CH...)copy SMILEScopy InChI
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of [3H]5HT uptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249782(10-(5-(diethylamino)pentyl)acridin-9(10H)-one | CH...)copy SMILEScopy InChI
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249759(10-(2-(diethylamino)ethyl)acridin-9(10H)-one | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]5HT uptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249780(10-(3-(diethylamino)propyl)acridin-9(10H)-one | CH...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]5HT uptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249781(10-(4-(diethylamino)butyl)acridin-9(10H)-one | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]5HT uptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249759(10-(2-(diethylamino)ethyl)acridin-9(10H)-one | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249783(10-(6-(diethylamino)hexyl)acridin-9(10H)-one | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249759(10-(2-(diethylamino)ethyl)acridin-9(10H)-one | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249780(10-(3-(diethylamino)propyl)acridin-9(10H)-one | CH...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249781(10-(4-(diethylamino)butyl)acridin-9(10H)-one | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249783(10-(6-(diethylamino)hexyl)acridin-9(10H)-one | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249782(10-(5-(diethylamino)pentyl)acridin-9(10H)-one | CH...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249781(10-(4-(diethylamino)butyl)acridin-9(10H)-one | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249780(10-(3-(diethylamino)propyl)acridin-9(10H)-one | CH...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50010859(CHEMBL11 | IMIPRAMINE HYDROCHLORIDE | IMIPRAMINE P...)copy SMILEScopy InChI
Affinity DataIC50: 2.56E+4nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMedDrugBank
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM35229(3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-met...)copy SMILEScopy InChI
Affinity DataIC50: 8.20E+4nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed