Compile Data Set for Download or QSAR
Found 3866 with Last Name = 'sprankle' and Initial = 'kg'
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136934(3',4'-Dichloro-biphenyl-3-sulfonic acid (3-chloro-...)copy SMILEScopy InChI
Affinity DataKi:  1.60nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136916(3'-Chloro-4'-fluoro-biphenyl-3-sulfonic acid (3-ch...)copy SMILEScopy InChI
Affinity DataKi:  3.40nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136914(4'-Chloro-3'-methyl-biphenyl-3-sulfonic acid (3-ch...)copy SMILEScopy InChI
Affinity DataKi:  3.90nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136919(3',4'-Difluoro-biphenyl-3-sulfonic acid (3-chloro-...)copy SMILEScopy InChI
Affinity DataKi:  8.10nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136913(CHEMBL156794 | N-(3-Chloro-7-isobutylamino-1H-inda...)copy SMILEScopy InChI
Affinity DataKi:  10.8nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136936(3'-Trifluoromethyl-biphenyl-3-sulfonic acid (3-chl...)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136942(4'-Chloro-biphenyl-3-sulfonic acid (3-chloro-7-iso...)copy SMILEScopy InChI
Affinity DataKi:  12.5nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136911(4'-Trifluoromethyl-biphenyl-3-sulfonic acid (3-chl...)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136918(4'-Fluoro-3'-methyl-biphenyl-3-sulfonic acid (3-ch...)copy SMILEScopy InChI
Affinity DataKi:  14.6nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136935(3'-Methylsulfanyl-biphenyl-3-sulfonic acid (3-chlo...)copy SMILEScopy InChI
Affinity DataKi:  17nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136910(3'-Trifluoromethyl-biphenyl-3-sulfonic acid (7-iso...)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136943(3'-(2-Hydroxy-ethyl)-biphenyl-3-sulfonic acid (3-c...)copy SMILEScopy InChI
Affinity DataKi:  25nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136922(CHEMBL346924 | N-(3-Chloro-7-isobutylamino-1H-inda...)copy SMILEScopy InChI
Affinity DataKi:  28.5nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136907(CHEMBL153876 | N-(3-Chloro-7-isobutylamino-1H-inda...)copy SMILEScopy InChI
Affinity DataKi:  36nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136940(3'-Methyl-biphenyl-3-sulfonic acid (3-chloro-7-iso...)copy SMILEScopy InChI
Affinity DataKi:  36nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136930(CHEMBL154614 | N-(3-Chloro-7-isobutylamino-1H-inda...)copy SMILEScopy InChI
Affinity DataKi:  52nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136921(Biphenyl-3-sulfonic acid (3-chloro-7-isobutylamino...)copy SMILEScopy InChI
Affinity DataKi:  94nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136938(3'-Methyl-biphenyl-3-sulfonic acid (7-isobutylamin...)copy SMILEScopy InChI
Affinity DataKi:  100nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136939(3'-Ethyl-biphenyl-3-sulfonic acid (7-isobutylamino...)copy SMILEScopy InChI
Affinity DataKi:  125nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136908(CHEMBL153820 | N-(7-Isobutylamino-3-methyl-1H-inda...)copy SMILEScopy InChI
Affinity DataKi:  191nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136905(CHEMBL157223 | N-(7-Isobutylamino-3-methyl-1H-inda...)copy SMILEScopy InChI
Affinity DataKi:  240nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136926(Biphenyl-3-sulfonic acid (7-isobutylamino-3-methyl...)copy SMILEScopy InChI
Affinity DataKi:  498nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136927(4-Chloro-N-[3-chloro-7-(cyclopropylmethyl-amino)-1...)copy SMILEScopy InChI
Affinity DataKi:  500nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136923(4-Chloro-N-(3-chloro-7-isobutylamino-1H-indazol-5-...)copy SMILEScopy InChI
Affinity DataKi:  760nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136937(5-Dimethylamino-naphthalene-1-sulfonic acid (1H-in...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136931(4-Chloro-N-[3-chloro-7-(2,2-dimethyl-propylamino)-...)copy SMILEScopy InChI
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136928(CHEMBL153833 | N-(7-Benzylamino-3-chloro-1H-indazo...)copy SMILEScopy InChI
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136906(4-Chloro-N-[3-chloro-7-(3-methyl-but-2-enylamino)-...)copy SMILEScopy InChI
Affinity DataKi:  2.20E+3nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136941(4-Chloro-N-(3-chloro-7-phenethylamino-1H-indazol-5...)copy SMILEScopy InChI
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136944(4-Chloro-N-(3-chloro-7-ethylamino-1H-indazol-5-yl)...)copy SMILEScopy InChI
Affinity DataKi:  2.70E+3nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136932(5-Dimethylamino-naphthalene-1-sulfonic acid (1H-in...)copy SMILEScopy InChI
Affinity DataKi:  2.80E+3nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136925(4-Chloro-N-(3-methyl-1H-indazol-5-yl)-benzenesulfo...)copy SMILEScopy InChI
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136920(4-Chloro-N-[3-chloro-7-(3-methyl-butylamino)-1H-in...)copy SMILEScopy InChI
Affinity DataKi:  4.90E+3nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136912(4-Chloro-N-(3-chloro-1H-indazol-5-yl)-benzenesulfo...)copy SMILEScopy InChI
Affinity DataKi:  5.20E+3nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136909(4-Chloro-N-[3-chloro-7-(3,3-dimethyl-butylamino)-1...)copy SMILEScopy InChI
Affinity DataKi:  6.50E+3nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136917(CHEMBL345702 | N-[3-Chloro-5-(4-chloro-benzenesulf...)copy SMILEScopy InChI
Affinity DataKi:  1.10E+4nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136929(4-Chloro-N-(1H-indazol-6-yl)-benzenesulfonamide | ...)copy SMILEScopy InChI
Affinity DataKi:  1.70E+4nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136933(5-Dimethylamino-naphthalene-1-sulfonic acid (3-chl...)copy SMILEScopy InChI
Affinity DataKi:  2.20E+4nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136915(4-Chloro-N-(1H-indazol-5-yl)-benzenesulfonamide | ...)copy SMILEScopy InChI
Affinity DataKi:  2.70E+4nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136924(5-Dimethylamino-naphthalene-1-sulfonic acid (3-met...)copy SMILEScopy InChI
Affinity DataKi:  6.40E+4nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279443DPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of FLT3 autophosphorylation in human AML cells isolated from relapsed acute myeloid leukemia patient by Western blottingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50308060(16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of FLT3 autophosphorylation in human RS4-11 cells after 2 hrs by electrochemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of FLT3 autophosphorylation in human RS4-11 cells after 2 hrs by electrochemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibition of FLT3 autophosphorylation in human RS4-11 cells after 2 hrs by electrochemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)copy SMILEScopy InChI
Affinity DataIC50: 9.90nMAssay Description:Inhibition of FLT3 autophosphorylation in human RS4-11 cells after 2 hrs by electrochemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50326053(CHEMBL608533 | PKC-412)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of FLT3 autophosphorylation in human RS4-11 cells after 2 hrs by electrochemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM333480(1-(5-tert- butylisoxazol- 3-yl)-3-(3- (7-methoxy- ...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of BRAF V600E mutant-dependent MEK phosphorylation in A375 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6N6ZPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM333478(1-(5-tert- butylisoxazol- 3-yl)-3-(3- (7-methoxy- ...)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of BRAF V600E mutant-dependent MEK phosphorylation in A375 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6N6ZPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM333473(1-(5-tert- butylisoxazol- 3-yl)-3-{3- [7-methoxy- ...)copy SMILEScopy InChI
Affinity DataIC50: 59nMAssay Description:Inhibition of BRAF V600E mutant-dependent MEK phosphorylation in A375 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6N6ZPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM333445(1-(5-tert- butylisoxazol- 3-yl)-3-(3- (6,7- dimeth...)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibition of BRAF V600E mutant-dependent MEK phosphorylation in A375 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6N6ZPubMed
Displayed 1 to 50 (of 3866 total ) | Next | Last >>
Jump to: