Compile Data Set for Download or QSAR
Found 152 with Last Name = 'schlemmer' and Initial = 'kh'
TargetCoagulation factor X(Homo sapiens (Human))
Bayer HealthCare AG

LigandPNGBDBM7842(BAY 59-7939 Analog 17 | US8822458, 46)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMpH: 8.3 T: 2°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38QR6PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bayer HealthCare AG

LigandPNGBDBM7840(RIVAROXABAN | US8822458, 44 | US8822458, 97)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMpH: 8.3 T: 2°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Bayer HealthCare AG

LigandPNGBDBM12998(5-Chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 8.3 T: 2°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38QR6PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bayer HealthCare AG

LigandPNGBDBM12997(5-Chloro-N-({(5S)-3-[3-fluoro-4-(3-oxomorpholin-4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMpH: 8.3 T: 2°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38QR6PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bayer HealthCare AG

LigandPNGBDBM12999(BAY 59-7939 Analog 14 | N-({(5S)-3-[3-Amino-4-(3-o...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMpH: 8.3 T: 2°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38QR6PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bayer HealthCare AG

LigandPNGBDBM7552(BAY 59-7939 Analog 11 | US8822458, 17)copy SMILEScopy InChI
Affinity DataIC50: 4nMpH: 8.3 T: 2°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38QR6PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bayer HealthCare AG

LigandPNGBDBM7841(BAY 59-7939 Analog 18 | US8822458, 45 | US9359341,...)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38QR6PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50120247(3-(2,4-Dioxo-3,4,7,8-tetrahydro-2H,5H-thiopyrano[4...)copy SMILEScopy InChI
Affinity DataIC50: 8.5nMAssay Description:Concentration of the compound required to inhibit human recombinant Poly (ADP-ribose) polymerase 1 was determined using doseresponse inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0FTTPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bayer HealthCare AG

LigandPNGBDBM13008(4-Amino-5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorphol...)copy SMILEScopy InChI
Affinity DataIC50: 8.5nMAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38QR6PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50120236(3-(2,4-Dioxo-3,4,7,8-tetrahydro-2H,5H-thiopyrano[4...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibitory activity against human recombinant PARP-1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0FTTPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50120246(3-(2,4-Dioxo-3,4,7,8-tetrahydro-2H,5H-thiopyrano[4...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibitory activity against human recombinant PARP-1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0FTTPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50120257(3-(2,4-Dioxo-3,4,7,8-tetrahydro-2H,5H-thiopyrano[4...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against human recombinant PARP-1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0FTTPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50120237(3-(2,4-Dioxo-3,4,7,8-tetrahydro-2H,5H-thiopyrano[4...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against human recombinant PARP-1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0FTTPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50120269(CHEMBL322133 | N-[2-(4-Bromo-phenyl)-2-oxo-ethyl]-...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against human recombinant PARP-1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0FTTPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50120239(3-(2,4-Dioxo-3,4,7,8-tetrahydro-2H,5H-thiopyrano[4...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Concentration required to inhibit human recombinant PARP-1 was determined using cell protection assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0FTTPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50120251(CHEMBL108702 | N-[2-(3'-Amino-biphenyl-4-yl)-2-oxo...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against human recombinant PARP-1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0FTTPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50120244(CHEMBL108341 | N-(2-Biphenyl-4-yl-2-oxo-ethyl)-3-(...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against human recombinant PARP-1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0FTTPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50120262(3-(2,4-Dioxo-3,4,7,8-tetrahydro-2H,5H-thiopyrano[4...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Concentration required to inhibit human recombinant PARP-1 was determined using cell protection assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0FTTPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50120267(3-(2,4-Dioxo-3,4,7,8-tetrahydro-2H,5H-thiopyrano[4...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against human recombinant PARP-1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0FTTPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50120261(3-(2,4-Dioxo-3,4,7,8-tetrahydro-2H,5H-thiopyrano[4...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against human recombinant PARP-1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0FTTPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bayer HealthCare AG

LigandPNGBDBM13005(4-chloro-N-{[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38QR6PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50120262(3-(2,4-Dioxo-3,4,7,8-tetrahydro-2H,5H-thiopyrano[4...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Concentration required to inhibit human recombinant PARP-1 was determined using cell protection assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0FTTPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50120274(3-(2,4-Dioxo-3,4,5,6,7,8-hexahydro-2H-quinazolin-1...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibitory activity against human recombinant PARP-1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0FTTPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50120254(3-(2,4-Dioxo-3,4,7,8-tetrahydro-2H,5H-thiopyrano[4...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibitory activity against human recombinant PARP-1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0FTTPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50120242(3-(2,4-Dioxo-3,4,7,8-tetrahydro-2H,5H-thiopyrano[4...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibitory activity against human recombinant PARP-1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0FTTPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50120265(3-(2,4-Dioxo-3,4,7,8-tetrahydro-2H,5H-thiopyrano[4...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibitory activity against human recombinant PARP-1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0FTTPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bayer HealthCare AG

LigandPNGBDBM13004(5-Bromo-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)p...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38QR6PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bayer HealthCare AG

LigandPNGBDBM13010(5-Chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38QR6PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50120277(3-(2,4-Dioxo-3,4,7,8-tetrahydro-2H,5H-thiopyrano[4...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against human recombinant PARP-1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0FTTPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50120253(Benzoic acid 4-{2-[3-(2,4-dioxo-3,4,7,8-tetrahydro...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against human recombinant PARP-1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0FTTPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50120256(CHEMBL110115 | N-[2-(4-Difluoromethoxy-phenyl)-2-o...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against human recombinant PARP-1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0FTTPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50120238(3-(2,4-Dioxo-3,4,7,8-tetrahydro-2H,5H-thiopyrano[4...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Concentration required to inhibit human recombinant PARP-1 was determined using cell protection assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0FTTPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bayer HealthCare AG

LigandPNGBDBM12990(5-Chloro-N-{[(5S)-3-(3-fluoro-4-morpholin-4-ylphen...)copy SMILEScopy InChI
Affinity DataIC50: 32nMpH: 8.3 T: 2°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38QR6PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50120241(3-(2,4-Dioxo-3,4,7,8-tetrahydro-2H,5H-thiopyrano[4...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Concentration required to inhibit human recombinant PARP-1 was determined using cell protection assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0FTTPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50120272(3-(2,4-Dioxo-3,4,7,8-tetrahydro-2H,5H-thiopyrano[4...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against human recombinant PARP-1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0FTTPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50120249(3-(2,4-Dioxo-3,4,7,8-tetrahydro-2H,5H-thiopyrano[4...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against human recombinant PARP-1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0FTTPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bayer HealthCare AG

LigandPNGBDBM12992(5-Chloro-N-{[(5S)-3-(3-fluoro-4-pyrrolidin-1-ylphe...)copy SMILEScopy InChI
Affinity DataIC50: 40nMpH: 8.3 T: 2°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38QR6PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bayer HealthCare AG

LigandPNGBDBM7495(BAY 59-7939 Analog 7 | US8822458, 2)copy SMILEScopy InChI
Affinity DataIC50: 43nMpH: 8.3 T: 2°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38QR6PubMed
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