Compile Data Set for Download or QSAR
Found 566 with Last Name = 'yoo' and Initial = 'kh'
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50069294((S)-3-[4-(carbohydrazonamidol)-phenyl]-N-cyclopent...)copy SMILEScopy InChI
Affinity DataKi:  0.380nMAssay Description:Compound was tested for inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CR5SHRPubMed
TargetProthrombin(Bos taurus (Bovine))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50069294((S)-3-[4-(carbohydrazonamidol)-phenyl]-N-cyclopent...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Compound was tested for inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CR5SHRPubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))TBA
LigandPNGBDBM50355500(CHEMBL1908394 | US9695172, GSK461364)copy SMILEScopy InChI
Affinity DataKi:  2.20nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8BM3PubMed
TargetProthrombin(Bos taurus (Bovine))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50069292(CHEMBL156082 | N-ethyl-N-cyclopentyl-3-(4-hydrazon...)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Compound was tested for inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CR5SHRPubMed
TargetProthrombin(Bos taurus (Bovine))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50069293(CHEMBL440188 | N-methyl-N-n-butyl-3-(4-hydrazonofo...)copy SMILEScopy InChI
Affinity DataKi:  41nMAssay Description:Compound was tested for inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CR5SHRPubMed
TargetProthrombin(Bos taurus (Bovine))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50069296(CHEMBL347371 | N-(n-propyl)-N-cyclopentyl-3-(4-hyd...)copy SMILEScopy InChI
Affinity DataKi:  93nMAssay Description:Compound was tested for inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CR5SHRPubMed
TargetProthrombin(Bos taurus (Bovine))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50069298(CHEMBL434678 | N-methyl-N-cyclohexyl-3-(4-hydrazon...)copy SMILEScopy InChI
Affinity DataKi:  152nMAssay Description:Compound was tested for inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CR5SHRPubMed
TargetProthrombin(Bos taurus (Bovine))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50069299(CHEMBL155317 | N-(n-butyl)-N-cyclopentyl-3-(4-hydr...)copy SMILEScopy InChI
Affinity DataKi:  231nMAssay Description:Compound was tested for inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CR5SHRPubMed
TargetProthrombin(Bos taurus (Bovine))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50069295(CHEMBL348175 | N-methyl-N-cyclopropyl-3-(4-hydrazo...)copy SMILEScopy InChI
Affinity DataKi:  247nMAssay Description:Compound was tested for inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CR5SHRPubMed
TargetProthrombin(Bos taurus (Bovine))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50069300(CHEMBL350901 | N-hydroxy-N-cyclopentyl-3-(4-hydraz...)copy SMILEScopy InChI
Affinity DataKi:  367nMAssay Description:Compound was tested for inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CR5SHRPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50069294((S)-3-[4-(carbohydrazonamidol)-phenyl]-N-cyclopent...)copy SMILEScopy InChI
Affinity DataKi:  1.10E+3nMAssay Description:The compound was tested for inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CR5SHRPubMed
TargetProthrombin(Bos taurus (Bovine))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50069297(1-[3-[4-amino(amineimino)methylphenyl]-2-(2-naphth...)copy SMILEScopy InChI
Affinity DataKi:  1.47E+3nMAssay Description:Compound was tested for inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CR5SHRPubMed
TargetTrypsin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50069294((S)-3-[4-(carbohydrazonamidol)-phenyl]-N-cyclopent...)copy SMILEScopy InChI
Affinity DataKi:  3.29E+3nMAssay Description:Compound was tested for inhibitory activity against bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CR5SHRPubMed
TargetProthrombin(Bos taurus (Bovine))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50069301(CHEMBL155311 | N-hydroxyethyl-N-cyclopentyl-3-(4-h...)copy SMILEScopy InChI
Affinity DataKi:  7.04E+3nMAssay Description:Compound was tested for inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CR5SHRPubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50069294((S)-3-[4-(carbohydrazonamidol)-phenyl]-N-cyclopent...)copy SMILEScopy InChI
Affinity DataKi:  2.72E+4nMAssay Description:The compound was tested for inhibitory activity against tissue plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CR5SHRPubMed
TargetPlasminogen(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50069294((S)-3-[4-(carbohydrazonamidol)-phenyl]-N-cyclopent...)copy SMILEScopy InChI
Affinity DataKi:  4.79E+4nMAssay Description:The compound was tested for inhibitory activity against human plasminMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CR5SHRPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

US Patent
LigandPNGBDBM435718(US10570155, Compound 2II | US11332479, Compound 2I...)copy SMILEScopy InChI
Affinity DataIC50: 0.0400nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N300B1US Patent
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

US Patent
LigandPNGBDBM435718(US10570155, Compound 2II | US11332479, Compound 2I...)copy SMILEScopy InChI
Affinity DataIC50: 0.0400nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ93MQUS Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))TBA
LigandPNGBDBM554464(US11332479, Compound 50III)copy SMILES
Affinity DataIC50: 0.0500nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ93MQUS Patent
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

US Patent
LigandPNGBDBM50585092(CHEMBL5087577)copy SMILES
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of human BRAF V600E mutant using myelin basic protein as substrate in presence of [gamma-33P]ATP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0SMNPubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)copy SMILEScopy InChI
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of ROS1 by HotSpot assay relative to controlMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z89CG9PubMed
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))TBA
LigandPNGBDBM554470(US11332479, Compound 72IV)copy SMILES
Affinity DataIC50: 0.0800nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ93MQUS Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))TBA
LigandPNGBDBM554469(US11332479, Compound 70IV)copy SMILES
Affinity DataIC50: 0.150nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ93MQUS Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))TBA
LigandPNGBDBM554462(US11332479, Compound 46III)copy SMILES
Affinity DataIC50: 0.150nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ93MQUS Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))TBA
LigandPNGBDBM554471(US11332479, Compound 73IV)copy SMILES
Affinity DataIC50: 0.160nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ93MQUS Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))TBA
LigandPNGBDBM554463(US11332479, Compound 48III)copy SMILES
Affinity DataIC50: 0.270nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ93MQUS Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))TBA
LigandPNGBDBM554467(US11332479, Compound 64IV)copy SMILES
Affinity DataIC50: 0.360nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ93MQUS Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))TBA
LigandPNGBDBM554460(US11332479, Compound 42III)copy SMILES
Affinity DataIC50: 0.360nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ93MQUS Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))TBA
LigandPNGBDBM554468(US11332479, Compound 65IV)copy SMILES
Affinity DataIC50: 0.370nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ93MQUS Patent
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of c-Met kinase (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

US Patent
LigandPNGBDBM50457446(CHEMBL4212692)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of BRAF (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50506637(CHEMBL4476226)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of N-terminal His-tagged recombinant human AXL (473 to end amino acids) expressed by baculovirus in Sf9 cells using axltide substrate and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9MHDPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

US Patent
LigandPNGBDBM50428286(DABRAFENIB | GSK2118436A)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50506637(CHEMBL4476226)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human AXL using EAIYAAPFAKKK as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9MHDPubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50296896((S)-2-(3-(3-hydroxy-5-methylphenyl)-4-(6-(2-hydrox...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of ALK (unknown origin) incubated for 20 mins followed by [33P]ATP addition measured after 120 mins by HotSpot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MX6PubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50062357(AP26113 | CHEMBL3397300)copy SMILEScopy InChI
Affinity DataIC50: 0.620nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MX6PubMed
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))TBA
LigandPNGBDBM435718(US10570155, Compound 2II | US11332479, Compound 2I...)copy SMILEScopy InChI
Affinity DataIC50: 0.670nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ93MQUS Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))TBA
LigandPNGBDBM435718(US10570155, Compound 2II | US11332479, Compound 2I...)copy SMILEScopy InChI
Affinity DataIC50: 0.670nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N300B1US Patent
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of ROS1 (unknown origin)More data for this Ligand-Target Pair
LigandPNGBDBM435718(US10570155, Compound 2II | US11332479, Compound 2I...)copy SMILEScopy InChI
Affinity DataIC50: 0.75nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ93MQUS Patent
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

US Patent
LigandPNGBDBM435718(US10570155, Compound 2II | US11332479, Compound 2I...)copy SMILEScopy InChI
Affinity DataIC50: 0.75nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N300B1US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50506648(CHEMBL4445940)copy SMILEScopy InChI
Affinity DataIC50: 0.940nMAssay Description:Inhibition of N-terminal His-tagged recombinant human AXL (473 to end amino acids) expressed by baculovirus in Sf9 cells using axltide substrate and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9MHDPubMed
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))TBA
LigandPNGBDBM435722(US10570155, Compound 31III)copy SMILEScopy InChI
Affinity DataIC50: 0.980nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N300B1US Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))TBA
LigandPNGBDBM554457(US11332479, Compound 31II)copy SMILES
Affinity DataIC50: 0.980nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ93MQUS Patent
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

US Patent
LigandPNGBDBM50585081(CHEMBL5086749)copy SMILES
Affinity DataIC50: 0.980nMAssay Description:Inhibition of human BRAF V600E mutant using myelin basic protein as substrate in presence of [gamma-33P]ATP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0SMNPubMed
TargetInsulin receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50587680(CHEMBL5182271)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8BM3PubMed
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))TBA
LigandPNGBDBM435721(US10570155, Compound 25III | US11332479, Compound ...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N300B1US Patent
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

US Patent
LigandPNGBDBM435721(US10570155, Compound 25III | US11332479, Compound ...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human BRAF V600E mutant using myelin basic protein as substrate in presence of [gamma-33P]ATP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0SMNPubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50587677(CHEMBL5173501)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8BM3PubMed
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))TBA
LigandPNGBDBM435721(US10570155, Compound 25III | US11332479, Compound ...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ93MQUS Patent
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