Compile Data Set for Download or QSAR
Found 13 with Last Name = 'seidl' and Initial = 'kj'
TargetMitogen-activated protein kinase kinase kinase 8(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM21898(8-chloro-4-[(3-chloro-4-fluorophenyl)amino]-6-[(1H...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of human Tpl2 by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6RBPPubMed
TargetMitogen-activated protein kinase kinase kinase 8(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50173834((R)-4-(3-chloro-4-fluorophenylamino)-6-(1-phenylet...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human Tpl2 by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6RBPPubMed
TargetStromelysin-1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM21898(8-chloro-4-[(3-chloro-4-fluorophenyl)amino]-6-[(1H...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of IL-1-beta-stimulated MMP3 in human RA-FLS cells by immunoblot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6RBPPubMed
TargetMitogen-activated protein kinase kinase kinase 8(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50173830((S)-4-(3-chloro-4-fluorophenylamino)-6-(1-phenylet...)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of human Tpl2 by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6RBPPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Oryctolagus cuniculus (rabbit))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM21898(8-chloro-4-[(3-chloro-4-fluorophenyl)amino]-6-[(1H...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of rabbit MEK1 by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6RBPPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM21898(8-chloro-4-[(3-chloro-4-fluorophenyl)amino]-6-[(1H...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human EGFR by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6RBPPubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM21898(8-chloro-4-[(3-chloro-4-fluorophenyl)amino]-6-[(1H...)copy SMILEScopy InChI
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of human MK2 by scintiplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6RBPPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM21898(8-chloro-4-[(3-chloro-4-fluorophenyl)amino]-6-[(1H...)copy SMILEScopy InChI
Affinity DataIC50: 7.30E+4nMAssay Description:Inhibition of human IKK-beta by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6RBPPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM21898(8-chloro-4-[(3-chloro-4-fluorophenyl)amino]-6-[(1H...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human Raf1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6RBPPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM21898(8-chloro-4-[(3-chloro-4-fluorophenyl)amino]-6-[(1H...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human Src by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6RBPPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM21898(8-chloro-4-[(3-chloro-4-fluorophenyl)amino]-6-[(1H...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human p38alpha by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6RBPPubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM21898(8-chloro-4-[(3-chloro-4-fluorophenyl)amino]-6-[(1H...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PKCalpha by scintiplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6RBPPubMed
TargetDual specificity mitogen-activated protein kinase kinase 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM21898(8-chloro-4-[(3-chloro-4-fluorophenyl)amino]-6-[(1H...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human MKK6 by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6RBPPubMed