Compile Data Set for Download or QSAR
Found 184 with Last Name = 'yeoh' and Initial = 'kk'
TargetLysine-specific demethylase 2A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50395076(CHEMBL2164243)copy SMILEScopy InChI
Affinity DataKi:  1.97E+3nMAssay Description:Competitive inhibition of human KDM2A expressed in Escherichia coli using 2-oxoglutarate by enzyme kinetic assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3N9SPubMed
TargetLysine-specific demethylase 2A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50395076(CHEMBL2164243)copy SMILEScopy InChI
Affinity DataKi:  8.50E+4nMAssay Description:Mixed type inhibition of human KDM2A expressed in Escherichia coli assessed inhibition constant for compound-enzyme-substrate complex using methyl ly...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3N9SPubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50303765(2-(3-hydroxy-2-((naphthalen-2-ylsulfonyl)carbonyli...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of human PHD2 at 293K temperature by solvent relaxation techniqueMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4WWNPubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50193145(2-(1-chloro-4-hydroxyisoquinoline-3-carboxamido)ac...)copy SMILEScopy InChI
Affinity DataIC50: 73nMAssay Description:Inhibition of human PHD2 at 293K temperature by solvent relaxation techniqueMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 4E(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50395083(CHEMBL2164246)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of human KDM4E expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3N9SPubMed
TargetLysine-specific demethylase 2A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50395083(CHEMBL2164246)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of human KDM2A expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3N9SPubMed
TargetLysine-specific demethylase 2A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50395078(CHEMBL2164245)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Inhibition of human KDM2A expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3N9SPubMed
TargetLysine-specific demethylase 4E(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50129197(4-(Hydroxyamino)-4-oxobutanoic acid | CHEMBL51979 ...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of human KDM4E expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3N9SPubMed
TargetLysine-specific demethylase 2A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50129197(4-(Hydroxyamino)-4-oxobutanoic acid | CHEMBL51979 ...)copy SMILEScopy InChI
Affinity DataIC50: 430nMAssay Description:Inhibition of human KDM2A expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3N9SPubMed
TargetHistone lysine demethylase PHF8(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50395083(CHEMBL2164246)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Inhibition of human PHF8 expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3N9SPubMed
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50395083(CHEMBL2164246)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Inhibition of human KDM5C catalytic domain expressed in Sf9 cells using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3N9SPubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50277935((S)-2-(1-chloro-4-hydroxyisoquinoline-3-carboxamid...)copy SMILEScopy InChI
Affinity DataIC50: 512nMAssay Description:Inhibition of human PHD2 at 293K temperature by solvent relaxation techniqueMore data for this Ligand-Target Pair
TargetHistone lysine demethylase PHF8(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50395076(CHEMBL2164243)copy SMILEScopy InChI
Affinity DataIC50: 550nMAssay Description:Inhibition of human PHF8 expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 2A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50197063(4,6-dioxoheptanoic acid | CHEMBL222824 | succinyla...)copy SMILEScopy InChI
Affinity DataIC50: 570nMAssay Description:Inhibition of human KDM2A expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3N9SPubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50129197(4-(Hydroxyamino)-4-oxobutanoic acid | CHEMBL51979 ...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human KDM6B catalytic domain expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3N9SPubMed
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50395078(CHEMBL2164245)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human KDM5C catalytic domain expressed in Sf9 cells using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3N9SPubMed
TargetLysine-specific demethylase 2A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50395076(CHEMBL2164243)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human KDM2A expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3N9SPubMed
TargetLysine-specific demethylase 2A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50395076(CHEMBL2164243)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human KDM2A expressed in Escherichia coli by formaldehyde dehydrogenase coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3N9SPubMed
TargetHistone lysine demethylase PHF8(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50129197(4-(Hydroxyamino)-4-oxobutanoic acid | CHEMBL51979 ...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human PHF8 expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3N9SPubMed
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50129197(4-(Hydroxyamino)-4-oxobutanoic acid | CHEMBL51979 ...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human KDM5C catalytic domain expressed in Sf9 cells using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3N9SPubMed
TargetLysine-specific demethylase 7A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50395076(CHEMBL2164243)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human KDM7A catalytic domain expressed in Escherichia coli by MALDI assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3N9SPubMed
TargetHistone lysine demethylase PHF8(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50197063(4,6-dioxoheptanoic acid | CHEMBL222824 | succinyla...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human PHF8 expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3N9SPubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50193145(2-(1-chloro-4-hydroxyisoquinoline-3-carboxamido)ac...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human hexahistidine-tagged full-length FTO expressed in Escherichia coli BL21 (DE3) using 3-methylthymidine as substrate assessed as in...More data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50396018(CHEMBL1230640)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human hexahistidine-tagged full-length FTO expressed in Escherichia coli BL21 (DE3) using 3-methylthymidine as substrate assessed as in...More data for this Ligand-Target Pair
TargetHistone lysine demethylase PHF8(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50395078(CHEMBL2164245)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human PHF8 expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3N9SPubMed
TargetLysine-specific demethylase 2A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50395082(CHEMBL2164247)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of human KDM2A expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3N9SPubMed
TargetLysine-specific demethylase 4E(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50395078(CHEMBL2164245)copy SMILEScopy InChI
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human KDM4E expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3N9SPubMed
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50197063(4,6-dioxoheptanoic acid | CHEMBL222824 | succinyla...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of human KDM5C catalytic domain expressed in Sf9 cells using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3N9SPubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50395080(CHEMBL2164249)copy SMILEScopy InChI
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of human PHD2 expressed in Escherichia coli by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3N9SPubMed
TargetHistone lysine demethylase PHF8(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50395080(CHEMBL2164249)copy SMILEScopy InChI
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of human PHF8 expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3N9SPubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM26113(2,4 PDCA | cid_10365 | pyridine carboxylate, 6a | ...)copy SMILEScopy InChI
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of human hexahistidine-tagged full-length FTO expressed in Escherichia coli BL21 (DE3) using 3-methylthymidine as substrate assessed as in...More data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50431024(CHEMBL2338321)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human hexahistidine-tagged full-length FTO expressed in Escherichia coli BL21 (DE3) using 3-methylthymidine as substrate assessed as in...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5GBQPubMed
TargetLysine-specific demethylase 2A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50395080(CHEMBL2164249)copy SMILEScopy InChI
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of human KDM2A expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3N9SPubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50431015(CHEMBL2338329 | US10889546, FG-4592 | US9115085, C...)copy SMILEScopy InChI
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of human hexahistidine-tagged full-length FTO expressed in Escherichia coli BL21 (DE3) using 3-methylthymidine as substrate assessed as in...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5GBQPubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50371704(CHEMBL270415)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human hexahistidine-tagged full-length FTO expressed in Escherichia coli BL21 (DE3) using 3-methylthymidine as substrate assessed as in...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5GBQPubMed
TargetHistone lysine demethylase PHF8(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50395082(CHEMBL2164247)copy SMILEScopy InChI
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibition of human PHF8 expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3N9SPubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50395078(CHEMBL2164245)copy SMILEScopy InChI
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of human PHD2 expressed in Escherichia coli by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3N9SPubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50328019(2-(3-hydroxypicolinamido)acetic acid | CHEMBL12565...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human hexahistidine-tagged full-length FTO expressed in Escherichia coli BL21 (DE3) using 3-methylthymidine as substrate assessed as in...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50197063(4,6-dioxoheptanoic acid | CHEMBL222824 | succinyla...)copy SMILEScopy InChI
Affinity DataIC50: 1.65E+4nMAssay Description:Inhibition of human KDM6B catalytic domain expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3N9SPubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50431022(CHEMBL2338323)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human hexahistidine-tagged full-length FTO expressed in Escherichia coli BL21 (DE3) using 3-methylthymidine as substrate assessed as in...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5GBQPubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)copy SMILEScopy InChI
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibition of human PHD2 at 293K temperature by solvent relaxation techniqueMore data for this Ligand-Target Pair
TargetEgl nine homolog 1(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50129197(4-(Hydroxyamino)-4-oxobutanoic acid | CHEMBL51979 ...)copy SMILEScopy InChI
Affinity DataIC50: 1.96E+4nMAssay Description:Inhibition of human PHD2 expressed in Escherichia coli by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3N9SPubMed
TargetLysine-specific demethylase 2A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50193145(2-(1-chloro-4-hydroxyisoquinoline-3-carboxamido)ac...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMpH: 7.5Assay Description:Inhibition assays were carried out in 384-well white ProxiPlates(PerkinElmer) in 10 μL of reaction volume. Standard reaction mixturesconsisted o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z93HFPubMed
TargetLysine-specific demethylase 3A(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM50193145(2-(1-chloro-4-hydroxyisoquinoline-3-carboxamido)ac...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMpH: 7.5Assay Description:Inhibition assays were carried out in 384-well white ProxiPlates(PerkinElmer) in 10 μL of reaction volume. Standard reaction mixturesconsisted o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z93HFPubMed
TargetLysine-specific demethylase 4E(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50193145(2-(1-chloro-4-hydroxyisoquinoline-3-carboxamido)ac...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMpH: 7.5Assay Description:Inhibition assays were carried out in 384-well white ProxiPlates(PerkinElmer) in 10 μL of reaction volume. Standard reaction mixturesconsisted o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z93HFPubMed
TargetLysine-specific demethylase 4C [1-973](Homo sapiens (Human))
University of Oxford

LigandPNGBDBM50193145(2-(1-chloro-4-hydroxyisoquinoline-3-carboxamido)ac...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMpH: 7.5Assay Description:Inhibition assays were carried out in 384-well white ProxiPlates(PerkinElmer) in 10 μL of reaction volume. Standard reaction mixturesconsisted o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z93HFPubMed
TargetLysine-specific demethylase 4A [1-973](Homo sapiens (Human))
University of Oxford

LigandPNGBDBM50193145(2-(1-chloro-4-hydroxyisoquinoline-3-carboxamido)ac...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMpH: 7.5Assay Description:Inhibition assays were carried out in 384-well white ProxiPlates(PerkinElmer) in 10 μL of reaction volume. Standard reaction mixturesconsisted o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z93HFPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM50193145(2-(1-chloro-4-hydroxyisoquinoline-3-carboxamido)ac...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMpH: 7.5Assay Description:Inhibition assays were carried out in 384-well white ProxiPlates(PerkinElmer) in 10 μL of reaction volume. Standard reaction mixturesconsisted o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z93HFPubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50431023(CHEMBL2338322)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human hexahistidine-tagged full-length FTO expressed in Escherichia coli BL21 (DE3) using 3-methylthymidine as substrate assessed as in...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5GBQPubMed
TargetLysine-specific demethylase 4E(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50197063(4,6-dioxoheptanoic acid | CHEMBL222824 | succinyla...)copy SMILEScopy InChI
Affinity DataIC50: 2.39E+4nMAssay Description:Inhibition of human KDM4E expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3N9SPubMed
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