Compile Data Set for Download or QSAR
Found 109 with Last Name = 'kavanagh' and Initial = 'kl'
TargetPutative farnesyl pyrophosphate synthase(Cryptosporidium parvum)
University of Toronto

LigandPNGBDBM12578(2-(imidazol-1-yl)-1-hydroxyethylidene-1,1-bisphosp...)copy SMILEScopy InChI
Affinity DataKi:  0.0500nM ΔG°:  -61.2kJ/mole IC50: 30.1nMpH: 7.7 T: 2°CAssay Description:Enzymatic assay using CpNPPPS was assayed using Reed and Rilling method with some modification. More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM12578(2-(imidazol-1-yl)-1-hydroxyethylidene-1,1-bisphosp...)copy SMILEScopy InChI
Affinity DataKi:  0.0700nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM12576(Bisphosphonate 1 | CHEMBL923 | JMC515594 Compound ...)copy SMILEScopy InChI
Affinity DataKi:  0.360nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
TargetPutative farnesyl pyrophosphate synthase(Cryptosporidium parvum)
University of Toronto

LigandPNGBDBM12576(Bisphosphonate 1 | CHEMBL923 | JMC515594 Compound ...)copy SMILEScopy InChI
Affinity DataKi:  0.380nM ΔG°:  -55.9kJ/mole IC50: 45.7nMpH: 7.7 T: 2°CAssay Description:Enzymatic assay using CpNPPPS was assayed using Reed and Rilling method with some modification. More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50098378((1-Hydroxy-1-phosphono-2-pyridin-2-yl-ethyl)-phosp...)copy SMILEScopy InChI
Affinity DataKi:  0.740nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50373094(CHEMBL408608)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50098390((3-methylpyridin-2-ylamino)methylenediphosphonic a...)copy SMILEScopy InChI
Affinity DataKi:  1.09nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetPutative farnesyl pyrophosphate synthase(Cryptosporidium parvum)
University of Toronto

LigandPNGBDBM81349(IBAN)copy SMILEScopy InChI
Affinity DataKi:  1.60nM ΔG°:  -52.2kJ/mole IC50: 52.7nMpH: 7.7 T: 2°CAssay Description:Enzymatic assay using CpNPPPS was assayed using Reed and Rilling method with some modification. More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25B00XQPubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50373098(CHEMBL259729)copy SMILEScopy InChI
Affinity DataKi:  1.60nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50115104((pyridin-2-ylamino)methylenediphosphonic acid | 2-...)copy SMILEScopy InChI
Affinity DataKi:  2.30nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50115106(2-(pyridin-2-ylamino)ethane-1,1-diyldiphosphonic a...)copy SMILEScopy InChI
Affinity DataKi:  2.30nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50373097(CHEMBL406820)copy SMILEScopy InChI
Affinity DataKi:  3.28nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50173792(2-(2-aminophenyl)-1-hydroxyethane-1,1-diyldiphosph...)copy SMILEScopy InChI
Affinity DataKi:  3.40nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM12577(Bisphosphonate 2 | CHEMBL997 | JMC515594 Compound ...)copy SMILEScopy InChI
Affinity DataKi:  3.60nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50373099(CHEMBL99553 | NE-10575)copy SMILEScopy InChI
Affinity DataKi:  3.90nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50373096(CHEMBL99369 | Piridronic acid)copy SMILEScopy InChI
Affinity DataKi:  4.45nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50138725((1-phosphono-2-pyridin-3-yl-ethyl)-phosphonic acid...)copy SMILEScopy InChI
Affinity DataKi:  7.40nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50115115((Cyclohexylamino-phosphono-methyl)-phosphonic acid...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50373093(CHEMBL100154)copy SMILEScopy InChI
Affinity DataKi:  11.6nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50098390((3-methylpyridin-2-ylamino)methylenediphosphonic a...)copy SMILEScopy InChI
Affinity DataKi:  12.1nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50115104((pyridin-2-ylamino)methylenediphosphonic acid | 2-...)copy SMILEScopy InChI
Affinity DataKi:  29.1nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50138725((1-phosphono-2-pyridin-3-yl-ethyl)-phosphonic acid...)copy SMILEScopy InChI
Affinity DataKi:  34.8nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50115106(2-(pyridin-2-ylamino)ethane-1,1-diyldiphosphonic a...)copy SMILEScopy InChI
Affinity DataKi:  36.9nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50373096(CHEMBL99369 | Piridronic acid)copy SMILEScopy InChI
Affinity DataKi:  39.0nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM25313((4-amino-1-hydroxy-1-phosphonobutyl)phosphonic aci...)copy SMILEScopy InChI
Affinity DataKi:  44.2nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMedDrugBank
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50098380((5-Amino-1-hydroxy-1-phosphono-pentyl)-phosphonic ...)copy SMILEScopy InChI
Affinity DataKi:  48.2nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM12581((3-amino-1-hydroxy-1-phosphonopropyl)phosphonic ac...)copy SMILEScopy InChI
Affinity DataKi:  55.9nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50098378((1-Hydroxy-1-phosphono-2-pyridin-2-yl-ethyl)-phosp...)copy SMILEScopy InChI
Affinity DataKi:  59.3nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50115115((Cyclohexylamino-phosphono-methyl)-phosphonic acid...)copy SMILEScopy InChI
Affinity DataKi:  62.4nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50098383((6-amino-1-hydroxy-1-phosphono-hexyl)-phosphonic a...)copy SMILEScopy InChI
Affinity DataKi:  63.5nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50173792(2-(2-aminophenyl)-1-hydroxyethane-1,1-diyldiphosph...)copy SMILEScopy InChI
Affinity DataKi:  64.6nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50098382((1-Hydroxy-1-phosphono-3-pyridin-3-yl-propyl)-phos...)copy SMILEScopy InChI
Affinity DataKi:  78nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM12576(Bisphosphonate 1 | CHEMBL923 | JMC515594 Compound ...)copy SMILEScopy InChI
Affinity DataKi:  82.2nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM12578(2-(imidazol-1-yl)-1-hydroxyethylidene-1,1-bisphosp...)copy SMILEScopy InChI
Affinity DataKi:  85.9nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50373094(CHEMBL408608)copy SMILEScopy InChI
Affinity DataKi:  86.3nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50373097(CHEMBL406820)copy SMILEScopy InChI
Affinity DataKi:  112nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50373098(CHEMBL259729)copy SMILEScopy InChI
Affinity DataKi:  137nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50373095(CHEMBL98719)copy SMILEScopy InChI
Affinity DataKi:  155nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50373099(CHEMBL99553 | NE-10575)copy SMILEScopy InChI
Affinity DataKi:  177nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50098380((5-Amino-1-hydroxy-1-phosphono-pentyl)-phosphonic ...)copy SMILEScopy InChI
Affinity DataKi:  194nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM12577(Bisphosphonate 2 | CHEMBL997 | JMC515594 Compound ...)copy SMILEScopy InChI
Affinity DataKi:  195nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50373095(CHEMBL98719)copy SMILEScopy InChI
Affinity DataKi:  196nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM12579((1-hydroxy-2-phenyl-1-phosphonoethyl)phosphonic ac...)copy SMILEScopy InChI
Affinity DataKi:  303nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50373093(CHEMBL100154)copy SMILEScopy InChI
Affinity DataKi:  320nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM12581((3-amino-1-hydroxy-1-phosphonopropyl)phosphonic ac...)copy SMILEScopy InChI
Affinity DataKi:  331nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50098382((1-Hydroxy-1-phosphono-3-pyridin-3-yl-propyl)-phos...)copy SMILEScopy InChI
Affinity DataKi:  363nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM12579((1-hydroxy-2-phenyl-1-phosphonoethyl)phosphonic ac...)copy SMILEScopy InChI
Affinity DataKi:  368nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM25313((4-amino-1-hydroxy-1-phosphonobutyl)phosphonic aci...)copy SMILEScopy InChI
Affinity DataKi:  393nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMedDrugBank
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50098383((6-amino-1-hydroxy-1-phosphono-hexyl)-phosphonic a...)copy SMILEScopy InChI
Affinity DataKi:  416nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50079022(HP2O7(3-) | diphosphate | diphosphate(3-) | hydrog...)copy SMILEScopy InChI
Affinity DataKi:  2.98E+4nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
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