Compile Data Set for Download or QSAR
Found 37 with Last Name = 'mcdow-dunham' and Initial = 'kl'
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063780(1-(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofura...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FXDPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063779(1-(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofura...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FXDPubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063780(1-(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofura...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FXDPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063781(1-(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofura...)copy SMILEScopy InChI
Affinity DataIC50: 95nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FXDPubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063781(1-(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofura...)copy SMILEScopy InChI
Affinity DataIC50: 95nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FXDPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063783(1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-hex-5-yn-1-...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FXDPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063795(1-(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzo[b]t...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FXDPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063787(1-(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofura...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FXDPubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063783(1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-hex-5-yn-1-...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FXDPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063796(1-(8-tert-Butyl-1,4,4-trimethyl-1,2,3,4-tetrahydro...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FXDPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063793(1-(8-tert-Butyl-4,4-dimethyl-thiochroman-6-yl)-pen...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FXDPubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063793(1-(8-tert-Butyl-4,4-dimethyl-thiochroman-6-yl)-pen...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FXDPubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063795(1-(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzo[b]t...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FXDPubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063779(1-(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofura...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FXDPubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063796(1-(8-tert-Butyl-1,4,4-trimethyl-1,2,3,4-tetrahydro...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FXDPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063792(1-(8-tert-Butyl-4,4-dimethyl-chroman-6-yl)-4-cyclo...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FXDPubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50009859((+-)-2-(p-isobutylphenyl)propionic acid | (+-)-alp...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063783(1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-hex-5-yn-1-...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of 1-lipoxygenase (LOX)in RBL cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FXDPubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063797(1-(7-tert-Butyl-2,3-dihydro-benzofuran-5-yl)-4-cyc...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FXDPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063798(4-Cyclopropyl-1-(3-ethyl-3-methyl-2,3-dihydro-benz...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FXDPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063780(1-(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofura...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of 1-lipoxygenase (LOX)in RBL cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FXDPubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063787(1-(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofura...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FXDPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063791(4-Cyclopropyl-1-(3,3-dimethyl-2,3-dihydro-benzofur...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FXDPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063792(1-(8-tert-Butyl-4,4-dimethyl-chroman-6-yl)-4-cyclo...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of 1-lipoxygenase (LOX)in RBL cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FXDPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063787(1-(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofura...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of 1-lipoxygenase (LOX)in RBL cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FXDPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063781(1-(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofura...)copy SMILEScopy InChI
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of 1-lipoxygenase (LOX)in RBL cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FXDPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063779(1-(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofura...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of 1-lipoxygenase (LOX)in RBL cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FXDPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063797(1-(7-tert-Butyl-2,3-dihydro-benzofuran-5-yl)-4-cyc...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of 1-lipoxygenase (LOX)in RBL cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FXDPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063797(1-(7-tert-Butyl-2,3-dihydro-benzofuran-5-yl)-4-cyc...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FXDPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063798(4-Cyclopropyl-1-(3-ethyl-3-methyl-2,3-dihydro-benz...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of 1-lipoxygenase (LOX)in RBL cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FXDPubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063798(4-Cyclopropyl-1-(3-ethyl-3-methyl-2,3-dihydro-benz...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FXDPubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063792(1-(8-tert-Butyl-4,4-dimethyl-chroman-6-yl)-4-cyclo...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FXDPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063794(1-(7-Cyclopentyl-3,3-dimethyl-2,3-dihydro-benzofur...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FXDPubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063791(4-Cyclopropyl-1-(3,3-dimethyl-2,3-dihydro-benzofur...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FXDPubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50029614((SC-57666)1-[2-(4-fluorophenyl)-1-cyclopentenyl]-4...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FXDPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50009859((+-)-2-(p-isobutylphenyl)propionic acid | (+-)-alp...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063794(1-(7-Cyclopentyl-3,3-dimethyl-2,3-dihydro-benzofur...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FXDPubMed