Compile Data Set for Download or QSAR
Found 60 with Last Name = 'muller' and Initial = 'km'
TargetEgl nine homolog 1(Human)
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50264220(2-(1,6-diphenyl-1H-imidazo[4,5-c]pyridine-4-carbox...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of PHD2 (unknown origin) by fluorescence energy transfer analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2WB7PubMed
TargetEgl nine homolog 1(Human)
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50264219(2-(6-chloro-1-phenyl-1H-imidazo[4,5-c]pyridine-4-c...)copy SMILEScopy InChI
Affinity DataIC50: 66nMAssay Description:Inhibition of PHD2 (unknown origin) by fluorescence energy transfer analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2WB7PubMed
TargetEgl nine homolog 1(Human)
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50264174(2-(1-phenyl-1H-imidazo[4,5-c]pyridine-4-carboxamid...)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Inhibition of PHD2 (unknown origin) by fluorescence energy transfer analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2WB7PubMed
TargetEgl nine homolog 1(Human)
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50264175(2-(1-benzyl-1H-imidazo[4,5-c]pyridine-4-carboxamid...)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Inhibition of PHD2 (unknown origin) by fluorescence energy transfer analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2WB7PubMed
TargetEgl nine homolog 1(Human)
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50264176(2-(1-(4-bromophenyl)-1H-imidazo[4,5-c]pyridine-4-c...)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Inhibition of PHD2 (unknown origin) by fluorescence energy transfer analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2WB7PubMed
TargetEgl nine homolog 1(Human)
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50264177(2-(2-methyl-1-phenyl-1H-imidazo[4,5-c]pyridine-4-c...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of PHD2 (unknown origin) by fluorescence energy transfer analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2WB7PubMed
TargetEgl nine homolog 1(Human)
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50264173(2-(1-methyl-1H-imidazo[4,5-c]pyridine-4-carboxamid...)copy SMILEScopy InChI
Affinity DataIC50: 570nMAssay Description:Inhibition of PHD2 (unknown origin) by fluorescence energy transfer analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2WB7PubMed
TargetEgl nine homolog 1(Human)
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50264223(2-(1-phenyl-1H-benzo[d]imidazole-4-carboxamido)ace...)copy SMILEScopy InChI
Affinity DataIC50: 730nMAssay Description:Inhibition of PHD2 (unknown origin) by fluorescence energy transfer analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2WB7PubMed
TargetEgl nine homolog 1(Human)
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50264221(2-(4-hydroxy-8-iodoisoquinoline-3-carboxamido)acet...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of PHD2 (unknown origin) by fluorescence energy transfer analysisMore data for this Ligand-Target Pair
TargetEgl nine homolog 1(Human)
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50264217(2-(1H-imidazo[4,5-c]pyridine-4-carboxamido)acetic ...)copy SMILEScopy InChI
Affinity DataIC50: 2.82E+3nMAssay Description:Inhibition of PHD2 (unknown origin) by fluorescence energy transfer analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2WB7PubMed
TargetEgl nine homolog 1(Human)
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50264218(2-(1-phenyl-2-(trifluoromethyl)-1H-imidazo[4,5-c]p...)copy SMILEScopy InChI
Affinity DataIC50: 5.54E+3nMAssay Description:Inhibition of PHD2 (unknown origin) by fluorescence energy transfer analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2WB7PubMed
LigandPNGBDBM50336946(1-((4-(5-(2-Fluorobenzyl)benzo[d]thiazol-2-yl)-3-f...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERG by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HR9PubMed
TargetEgl nine homolog 1(Human)
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50264222(2-(9-phenyl-9H-purine-6-carboxamido)acetic acid | ...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of PHD2 (unknown origin) by fluorescence energy transfer analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2WB7PubMed
TargetEgl nine homolog 1(Human)
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50264179(2-(thieno[2,3-c]pyridine-7-carboxamido)acetic acid...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of PHD2 (unknown origin) by fluorescence energy transfer analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2WB7PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50335462(1-(4-(5-benzylbenzofuran-2-yl)-3-fluorobenzyl)azet...)copy SMILEScopy InChI
Affinity DataEC50:  1.73E+3nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO-K1 cells co-expressing Gq/i5 G-protein assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HR9PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50335512(1-(4-(5-benzylbenzo[d]thiazol-2-yl)-3-fluorobenzyl...)copy SMILEScopy InChI
Affinity DataEC50:  1.21E+3nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO-K1 cells co-expressing Gq/i5 G-protein assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HR9PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336952(1-(4-(5-Benzyl-2H-indazol-2-yl)-3-fluorobenzyl)aze...)copy SMILEScopy InChI
Affinity DataEC50:  1.11E+3nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO-K1 cells co-expressing Gq/i5 G-protein assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HR9PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336953(1-((4-(5-(3,4-Difluorobenzyl)benzo[d]thiazol-2-yl)...)copy SMILEScopy InChI
Affinity DataEC50:  967nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO-K1 cells co-expressing Gq/i5 G-protein assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HR9PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336954(1-((4-(5-(3-Fluorobenzyl)benzo[d]thiazol-2-yl)-3-f...)copy SMILEScopy InChI
Affinity DataEC50:  687nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO-K1 cells co-expressing Gq/i5 G-protein assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HR9PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336955(1-(4-(6-Benzylbenzofuran-2-yl)-3-fluorobenzyl)azet...)copy SMILEScopy InChI
Affinity DataEC50:  679nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO-K1 cells co-expressing Gq/i5 G-protein assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HR9PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336956(1-(4-(6-Benzylbenzo[d]oxazol-2-yl)-3-fluorobenzyl)...)copy SMILEScopy InChI
Affinity DataEC50:  542nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO-K1 cells co-expressing Gq/i5 G-protein assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HR9PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336957(1-(4-(5-Benzylbenzo[d]oxazol-2-yl)-3-fluorobenzyl)...)copy SMILEScopy InChI
Affinity DataEC50:  354nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO-K1 cells co-expressing Gq/i5 G-protein assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HR9PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336941(1-(4-(6-Benzyl-1H-benzo[d]imidazol-2-yl)-3-fluorob...)copy SMILEScopy InChI
Affinity DataEC50: >6.25E+3nMAssay Description:Agonist activity at human S1P1 receptor expressed in human U2OS cells co-expressing eGFP assessed as receptor internalization after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HR9PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336940(1-(4-(6-Benzylimidazo[1,2-a]pyridin-2-yl)-3-fluoro...)copy SMILEScopy InChI
Affinity DataEC50:  6.72E+3nMAssay Description:Agonist activity at human S1P1 receptor expressed in human U2OS cells co-expressing eGFP assessed as receptor internalization after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HR9PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336952(1-(4-(5-Benzyl-2H-indazol-2-yl)-3-fluorobenzyl)aze...)copy SMILEScopy InChI
Affinity DataEC50:  2.89E+3nMAssay Description:Agonist activity at human S1P1 receptor expressed in human U2OS cells co-expressing eGFP assessed as receptor internalization after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HR9PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336947(1-(4-(6-Benzyl-2H-indazol-2-yl)-3-fluorobenzyl)aze...)copy SMILEScopy InChI
Affinity DataEC50:  1.81E+3nMAssay Description:Agonist activity at human S1P1 receptor expressed in human U2OS cells co-expressing eGFP assessed as receptor internalization after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HR9PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336943(1-(4-(7-Benzylimidazo[1,2-a]pyridin-2-yl)-3-fluoro...)copy SMILEScopy InChI
Affinity DataEC50:  741nMAssay Description:Agonist activity at human S1P1 receptor expressed in human U2OS cells co-expressing eGFP assessed as receptor internalization after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HR9PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336957(1-(4-(5-Benzylbenzo[d]oxazol-2-yl)-3-fluorobenzyl)...)copy SMILEScopy InChI
Affinity DataEC50:  325nMAssay Description:Agonist activity at human S1P1 receptor expressed in human U2OS cells co-expressing eGFP assessed as receptor internalization after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HR9PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50335508(1-(4-(6-benzylbenzo[d]thiazol-2-yl)-3-fluorobenzyl...)copy SMILEScopy InChI
Affinity DataEC50:  221nMAssay Description:Agonist activity at human S1P1 receptor expressed in human U2OS cells co-expressing eGFP assessed as receptor internalization after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HR9PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336938(1-((4-(5-(4-Chlorobenzyl)benzo[d]thiazol-2-yl)-3-f...)copy SMILEScopy InChI
Affinity DataEC50:  159nMAssay Description:Agonist activity at human S1P1 receptor expressed in human U2OS cells co-expressing eGFP assessed as receptor internalization after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HR9PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336939(1-((4-(5-(2,6-Difluorobenzyl)benzo[d]thiazol-2-yl)...)copy SMILEScopy InChI
Affinity DataEC50:  126nMAssay Description:Agonist activity at human S1P1 receptor expressed in human U2OS cells co-expressing eGFP assessed as receptor internalization after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HR9PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336956(1-(4-(6-Benzylbenzo[d]oxazol-2-yl)-3-fluorobenzyl)...)copy SMILEScopy InChI
Affinity DataEC50:  94nMAssay Description:Agonist activity at human S1P1 receptor expressed in human U2OS cells co-expressing eGFP assessed as receptor internalization after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HR9PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336950(1-(3-Fluoro-4-(5-(4-methylbenzyl)benzo[d]thiazol-2...)copy SMILEScopy InChI
Affinity DataEC50:  77nMAssay Description:Agonist activity at human S1P1 receptor expressed in human U2OS cells co-expressing eGFP assessed as receptor internalization after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HR9PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50335462(1-(4-(5-benzylbenzofuran-2-yl)-3-fluorobenzyl)azet...)copy SMILEScopy InChI
Affinity DataEC50:  57nMAssay Description:Agonist activity at human S1P1 receptor expressed in human U2OS cells co-expressing eGFP assessed as receptor internalization after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HR9PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336942(1-(3-Fluoro-4-(5-(3-methylbenzyl)benzo[d]thiazol-2...)copy SMILEScopy InChI
Affinity DataEC50:  54nMAssay Description:Agonist activity at human S1P1 receptor expressed in human U2OS cells co-expressing eGFP assessed as receptor internalization after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HR9PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336945(1-((4-(5-(3-Chlorobenzyl)benzo[d]thiazol-2-yl)-3-f...)copy SMILEScopy InChI
Affinity DataEC50:  49nMAssay Description:Agonist activity at human S1P1 receptor expressed in human U2OS cells co-expressing eGFP assessed as receptor internalization after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HR9PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336944(1-((4-(5-(2-Chlorobenzyl)benzo[d]thiazol-2-yl)-3-f...)copy SMILEScopy InChI
Affinity DataEC50:  42nMAssay Description:Agonist activity at human S1P1 receptor expressed in human U2OS cells co-expressing eGFP assessed as receptor internalization after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HR9PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336951(1-((4-(5-(2,4-Difluorobenzyl)benzo[d]thiazol-2-yl)...)copy SMILEScopy InChI
Affinity DataEC50:  42nMAssay Description:Agonist activity at human S1P1 receptor expressed in human U2OS cells co-expressing eGFP assessed as receptor internalization after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HR9PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336946(1-((4-(5-(2-Fluorobenzyl)benzo[d]thiazol-2-yl)-3-f...)copy SMILEScopy InChI
Affinity DataEC50:  42nMAssay Description:Agonist activity at human S1P1 receptor expressed in human U2OS cells co-expressing eGFP assessed as receptor internalization after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HR9PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50335512(1-(4-(5-benzylbenzo[d]thiazol-2-yl)-3-fluorobenzyl...)copy SMILEScopy InChI
Affinity DataEC50:  42nMAssay Description:Agonist activity at human S1P1 receptor expressed in human U2OS cells co-expressing eGFP assessed as receptor internalization after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HR9PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336949(1-((4-(5-(4-Fluorobenzyl)benzo[d]thiazol-2-yl)-3-f...)copy SMILEScopy InChI
Affinity DataEC50:  33nMAssay Description:Agonist activity at human S1P1 receptor expressed in human U2OS cells co-expressing eGFP assessed as receptor internalization after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HR9PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336953(1-((4-(5-(3,4-Difluorobenzyl)benzo[d]thiazol-2-yl)...)copy SMILEScopy InChI
Affinity DataEC50:  30nMAssay Description:Agonist activity at human S1P1 receptor expressed in human U2OS cells co-expressing eGFP assessed as receptor internalization after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HR9PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336948(1-(3-Fluoro-4-(5-(2-methylbenzyl)benzo[d]thiazol-2...)copy SMILEScopy InChI
Affinity DataEC50:  26nMAssay Description:Agonist activity at human S1P1 receptor expressed in human U2OS cells co-expressing eGFP assessed as receptor internalization after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HR9PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336954(1-((4-(5-(3-Fluorobenzyl)benzo[d]thiazol-2-yl)-3-f...)copy SMILEScopy InChI
Affinity DataEC50:  21nMAssay Description:Agonist activity at human S1P1 receptor expressed in human U2OS cells co-expressing eGFP assessed as receptor internalization after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HR9PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336955(1-(4-(6-Benzylbenzofuran-2-yl)-3-fluorobenzyl)azet...)copy SMILEScopy InChI
Affinity DataEC50:  13nMAssay Description:Agonist activity at human S1P1 receptor expressed in human U2OS cells co-expressing eGFP assessed as receptor internalization after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HR9PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336950(1-(3-Fluoro-4-(5-(4-methylbenzyl)benzo[d]thiazol-2...)copy SMILEScopy InChI
Affinity DataEC50:  1.80E+3nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO-K1 cells co-expressing Gq/i5 G-protein assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HR9PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336949(1-((4-(5-(4-Fluorobenzyl)benzo[d]thiazol-2-yl)-3-f...)copy SMILEScopy InChI
Affinity DataEC50:  1.91E+3nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO-K1 cells co-expressing Gq/i5 G-protein assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HR9PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336948(1-(3-Fluoro-4-(5-(2-methylbenzyl)benzo[d]thiazol-2...)copy SMILEScopy InChI
Affinity DataEC50:  2.44E+3nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO-K1 cells co-expressing Gq/i5 G-protein assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HR9PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336947(1-(4-(6-Benzyl-2H-indazol-2-yl)-3-fluorobenzyl)aze...)copy SMILEScopy InChI
Affinity DataEC50:  2.71E+3nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO-K1 cells co-expressing Gq/i5 G-protein assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HR9PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50335508(1-(4-(6-benzylbenzo[d]thiazol-2-yl)-3-fluorobenzyl...)copy SMILEScopy InChI
Affinity DataEC50:  3.47E+3nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO-K1 cells co-expressing Gq/i5 G-protein assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HR9PubMed
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