Compile Data Set for Download or QSAR
Found 45 with Last Name = 'vaidya' and Initial = 'ks'
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
GlaxoSmithKline

LigandPNGBDBM8744(1-[(4-methylphenyl)methyl]-4-(thiophen-3-yl)-1H-im...)copy SMILEScopy InChI
Affinity DataIC50: 250nMpH: 6.5 T: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P5XQGPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
GlaxoSmithKline

LigandPNGBDBM8739(4-(4-methoxyphenyl)-1-[(4-methylphenyl)methyl]-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 360nMpH: 6.5 T: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P5XQGPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli)
GlaxoSmithKline

LigandPNGBDBM8726(5-chloro-2-(2,4-dichlorophenoxy)phenol | CHEMBL849...)copy SMILEScopy InChI
Affinity DataIC50: 430nMT: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
TargetUrotensin-2 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50241425(2-((3,4-dichlorophenyl)(methyl)amino)-1-(2-(pyrrol...)copy SMILEScopy InChI
Affinity DataIC50: 631nMAssay Description:Inhibition of human recombinant urotensin 2 receptor-mediated calcium mobilization expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1RXXPubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50239135(2-((3,4-dichlorophenyl)(methyl)amino)-1-((2R,3R)-3...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1RXXPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
GlaxoSmithKline

LigandPNGBDBM8726(5-chloro-2-(2,4-dichlorophenoxy)phenol | CHEMBL849...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMpH: 6.5 T: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
GlaxoSmithKline

LigandPNGBDBM8749(1-benzyl-4-(4-methoxyphenyl)-1H-imidazole | Disubs...)copy SMILEScopy InChI
Affinity DataIC50: 1.13E+3nMpH: 6.5 T: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P5XQGPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli)
GlaxoSmithKline

LigandPNGBDBM8748(1-[(4-phenylphenyl)methyl]-4-(thiophen-3-yl)-1H-im...)copy SMILEScopy InChI
Affinity DataIC50: 1.18E+3nMT: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P5XQGPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
GlaxoSmithKline

LigandPNGBDBM8738(1-[(4-methylphenyl)methyl]-4-(thiophen-2-yl)-1H-im...)copy SMILEScopy InChI
Affinity DataIC50: 1.24E+3nMpH: 6.5 T: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P5XQGPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50239135(2-((3,4-dichlorophenyl)(methyl)amino)-1-((2R,3R)-3...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1RXXPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
GlaxoSmithKline

LigandPNGBDBM8742(1-[(4-methoxyphenyl)methyl]-4-(thiophen-3-yl)-1H-i...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMpH: 6.5 T: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P5XQGPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
GlaxoSmithKline

LigandPNGBDBM8741(4-{[4-(thiophen-3-yl)-1H-imidazol-1-yl]methyl}anil...)copy SMILEScopy InChI
Affinity DataIC50: 2.03E+3nMpH: 6.5 T: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P5XQGPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli)
GlaxoSmithKline

LigandPNGBDBM8739(4-(4-methoxyphenyl)-1-[(4-methylphenyl)methyl]-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 3.92E+3nMT: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P5XQGPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
GlaxoSmithKline

LigandPNGBDBM8750(4-(4-methoxyphenyl)-1-{[4-(trifluoromethyl)phenyl]...)copy SMILEScopy InChI
Affinity DataIC50: 4.07E+3nMpH: 6.5 T: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P5XQGPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
GlaxoSmithKline

LigandPNGBDBM8746(1-[(3-methylphenyl)methyl]-4-(thiophen-3-yl)-1H-im...)copy SMILEScopy InChI
Affinity DataIC50: 4.24E+3nMpH: 6.5 T: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P5XQGPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli)
GlaxoSmithKline

LigandPNGBDBM8741(4-{[4-(thiophen-3-yl)-1H-imidazol-1-yl]methyl}anil...)copy SMILEScopy InChI
Affinity DataIC50: 5.14E+3nMT: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P5XQGPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli)
GlaxoSmithKline

LigandPNGBDBM8749(1-benzyl-4-(4-methoxyphenyl)-1H-imidazole | Disubs...)copy SMILEScopy InChI
Affinity DataIC50: 5.28E+3nMT: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P5XQGPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli)
GlaxoSmithKline

LigandPNGBDBM8744(1-[(4-methylphenyl)methyl]-4-(thiophen-3-yl)-1H-im...)copy SMILEScopy InChI
Affinity DataIC50: 6.44E+3nMT: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P5XQGPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
GlaxoSmithKline

LigandPNGBDBM8748(1-[(4-phenylphenyl)methyl]-4-(thiophen-3-yl)-1H-im...)copy SMILEScopy InChI
Affinity DataIC50: 7.66E+3nMpH: 6.5 T: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P5XQGPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli)
GlaxoSmithKline

LigandPNGBDBM8742(1-[(4-methoxyphenyl)methyl]-4-(thiophen-3-yl)-1H-i...)copy SMILEScopy InChI
Affinity DataIC50: 9.40E+3nMT: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P5XQGPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
GlaxoSmithKline

LigandPNGBDBM8752(4-(2,3-dichlorophenyl)-1-[(4-methylphenyl)methyl]-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMpH: 6.5 T: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P5XQGPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli)
GlaxoSmithKline

LigandPNGBDBM8746(1-[(3-methylphenyl)methyl]-4-(thiophen-3-yl)-1H-im...)copy SMILEScopy InChI
Affinity DataIC50: 1.22E+4nMT: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P5XQGPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli)
GlaxoSmithKline

LigandPNGBDBM8738(1-[(4-methylphenyl)methyl]-4-(thiophen-2-yl)-1H-im...)copy SMILEScopy InChI
Affinity DataIC50: 1.37E+4nMT: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
GlaxoSmithKline

LigandPNGBDBM8740(1-[(3-nitrophenyl)methyl]-4-(thiophen-3-yl)-1H-imi...)copy SMILEScopy InChI
Affinity DataIC50: 1.47E+4nMpH: 6.5 T: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P5XQGPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli)
GlaxoSmithKline

LigandPNGBDBM8740(1-[(3-nitrophenyl)methyl]-4-(thiophen-3-yl)-1H-imi...)copy SMILEScopy InChI
Affinity DataIC50: 2.69E+4nMT: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P5XQGPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli)
GlaxoSmithKline

LigandPNGBDBM8750(4-(4-methoxyphenyl)-1-{[4-(trifluoromethyl)phenyl]...)copy SMILEScopy InChI
Affinity DataIC50: 2.83E+4nMT: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P5XQGPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
GlaxoSmithKline

LigandPNGBDBM8747(1-[(2-methylphenyl)methyl]-4-(thiophen-3-yl)-1H-im...)copy SMILEScopy InChI
Affinity DataIC50: 3.65E+4nMpH: 6.5 T: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P5XQGPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
GlaxoSmithKline

LigandPNGBDBM8758(5-[(4-methylphenyl)methyl]-3-(thiophen-3-yl)-1,2,4...)copy SMILEScopy InChI
Affinity DataIC50: 5.07E+4nMpH: 6.5 T: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P5XQGPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
GlaxoSmithKline

LigandPNGBDBM8756(3-[(4-methylphenyl)methyl]-5-(thiophen-3-yl)-1,2,4...)copy SMILEScopy InChI
Affinity DataIC50: 5.10E+4nMpH: 6.5 T: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P5XQGPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli)
GlaxoSmithKline

LigandPNGBDBM8747(1-[(2-methylphenyl)methyl]-4-(thiophen-3-yl)-1H-im...)copy SMILEScopy InChI
Affinity DataIC50: 6.54E+4nMT: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P5XQGPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
GlaxoSmithKline

LigandPNGBDBM8753(5-(4-methoxyphenyl)-2-[(4-methylphenyl)methyl]-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 6.62E+4nMpH: 6.5 T: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P5XQGPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli)
GlaxoSmithKline

LigandPNGBDBM8754((4S)-4-benzyl-2-(thiophen-3-yl)-4,5-dihydro-1,3-ox...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P5XQGPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli)
GlaxoSmithKline

LigandPNGBDBM8755(4-[(4-methylphenyl)methyl]-2-(thiophen-3-yl)-1,3-o...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P5XQGPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli)
GlaxoSmithKline

LigandPNGBDBM8757((4R)-4-benzyl-2-(thiophen-3-yl)-4,5-dihydro-1,3-ox...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P5XQGPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli)
GlaxoSmithKline

LigandPNGBDBM8743(3-{[4-(thiophen-3-yl)-1H-imidazol-1-yl]methyl}benz...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P5XQGPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
GlaxoSmithKline

LigandPNGBDBM8755(4-[(4-methylphenyl)methyl]-2-(thiophen-3-yl)-1,3-o...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMpH: 6.5 T: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P5XQGPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli)
GlaxoSmithKline

LigandPNGBDBM8756(3-[(4-methylphenyl)methyl]-5-(thiophen-3-yl)-1,2,4...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P5XQGPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli)
GlaxoSmithKline

LigandPNGBDBM8753(5-(4-methoxyphenyl)-2-[(4-methylphenyl)methyl]-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P5XQGPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
GlaxoSmithKline

LigandPNGBDBM8754((4S)-4-benzyl-2-(thiophen-3-yl)-4,5-dihydro-1,3-ox...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMpH: 6.5 T: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P5XQGPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
GlaxoSmithKline

LigandPNGBDBM8745(1-methyl-4-(thiophen-3-yl)-1H-imidazole | Disubsti...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMpH: 6.5 T: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P5XQGPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli)
GlaxoSmithKline

LigandPNGBDBM8758(5-[(4-methylphenyl)methyl]-3-(thiophen-3-yl)-1,2,4...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P5XQGPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
GlaxoSmithKline

LigandPNGBDBM8751(1-benzyl-4-[4-(trifluoromethyl)phenyl]-1H-imidazol...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMpH: 6.5 T: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P5XQGPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
GlaxoSmithKline

LigandPNGBDBM8743(3-{[4-(thiophen-3-yl)-1H-imidazol-1-yl]methyl}benz...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMpH: 6.5 T: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P5XQGPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
GlaxoSmithKline

LigandPNGBDBM8757((4R)-4-benzyl-2-(thiophen-3-yl)-4,5-dihydro-1,3-ox...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMpH: 6.5 T: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P5XQGPubMed
TargetUrotensin-2 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50412075(CHEMBL404177)copy SMILEScopy InChI
Affinity DataKd:  10nMAssay Description:Antagonist activity at human urotensin 2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1RXXPubMed