Compile Data Set for Download or QSAR
Found 89 with Last Name = 'bernier' and Initial = 'l'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50112173(CHEMBL3608429)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50450885(CHEMBL4216749)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50450884(CHEMBL4211782)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50450887(CHEMBL4211367)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50450886(CHEMBL4206481)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50450871(CHEMBL4205392)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50450868(CHEMBL4216679)copy SMILEScopy InChI
Affinity DataKi:  8nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50450875(CHEMBL4208811)copy SMILEScopy InChI
Affinity DataKi:  9nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50450870(Mavelertinib | PF-06747775)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50112176(CHEMBL3608432)copy SMILEScopy InChI
Affinity DataKi:  17nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50450866(CHEMBL4208829)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50450869(CHEMBL4218154)copy SMILEScopy InChI
Affinity DataKi:  19nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50450873(CHEMBL4206312)copy SMILEScopy InChI
Affinity DataKi:  32nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50450865(CHEMBL4212326)copy SMILEScopy InChI
Affinity DataKi:  36nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50450889(CHEMBL4204498)copy SMILEScopy InChI
Affinity DataKi:  56nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50450879(CHEMBL4207951)copy SMILEScopy InChI
Affinity DataKi:  85nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50450888(CHEMBL4209368)copy SMILEScopy InChI
Affinity DataKi:  105nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50450880(CHEMBL4204566)copy SMILEScopy InChI
Affinity DataKi:  152nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50450890(CHEMBL4206604)copy SMILEScopy InChI
Affinity DataKi:  161nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50450882(CHEMBL4207425)copy SMILEScopy InChI
Affinity DataKi:  161nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50450874(CHEMBL4213741)copy SMILEScopy InChI
Affinity DataKi:  164nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50450883(CHEMBL4203072)copy SMILEScopy InChI
Affinity DataKi:  183nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50450868(CHEMBL4216679)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of EGFR T790M/exon 19 deletion mutant phosphorylation in human PC9-DRH cells preincubated for 2 hrs followed by EGF stimulation for 10 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetReceptor tyrosine-protein kinase erbB-3(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50210162(CHEMBL3883534)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of EGFR L858R mutant phosphorylation in human H3255 cells preincubated for 2 hrs followed by EGF stimulation for 10 mins by sandwich ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50210162(CHEMBL3883534)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of EGFR exon 19 deletion mutant phosphorylation in human PC9 cells preincubated for 2 hrs followed by EGF stimulation for 10 mins by sandw...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50112173(CHEMBL3608429)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of EGFR T790M/exon 19 deletion mutant phosphorylation in human PC9-DRH cells preincubated for 2 hrs followed by EGF stimulation for 10 min...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetReceptor tyrosine-protein kinase erbB-3(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50112173(CHEMBL3608429)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of EGFR L858R mutant phosphorylation in human H3255 cells preincubated for 2 hrs followed by EGF stimulation for 10 mins by sandwich ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetReceptor tyrosine-protein kinase erbB-3(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50450868(CHEMBL4216679)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of EGFR L858R mutant phosphorylation in human H3255 cells preincubated for 2 hrs followed by EGF stimulation for 10 mins by sandwich ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50450868(CHEMBL4216679)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of EGFR exon 19 deletion mutant phosphorylation in human PC9 cells preincubated for 2 hrs followed by EGF stimulation for 10 mins by sandw...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50450870(Mavelertinib | PF-06747775)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of EGFR T790M/exon 19 deletion mutant phosphorylation in human PC9-DRH cells preincubated for 2 hrs followed by EGF stimulation for 10 min...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50450869(CHEMBL4218154)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of EGFR T790M/exon 19 deletion mutant phosphorylation in human PC9-DRH cells preincubated for 2 hrs followed by EGF stimulation for 10 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50112176(CHEMBL3608432)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of EGFR T790M/exon 19 deletion mutant phosphorylation in human PC9-DRH cells preincubated for 2 hrs followed by EGF stimulation for 10 min...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetReceptor tyrosine-protein kinase erbB-3(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50450870(Mavelertinib | PF-06747775)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of EGFR L858R mutant phosphorylation in human H3255 cells preincubated for 2 hrs followed by EGF stimulation for 10 mins by sandwich ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50450868(CHEMBL4216679)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of EGFR T790M/L858R double mutant phosphorylation in human H1975 cells preincubated for 2 hrs followed by EGF stimulation for 10 mins by s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50450870(Mavelertinib | PF-06747775)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of EGFR exon 19 deletion mutant phosphorylation in human PC9 cells preincubated for 2 hrs followed by EGF stimulation for 10 mins by sandw...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50210162(CHEMBL3883534)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of EGF-stimulated wild-type EGFR phosphorylation in human A549 cells preincubated for 2 hrs followed by EGF stimulation for 10 mins by san...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50112173(CHEMBL3608429)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of EGFR T790M/L858R double mutant phosphorylation in human H1975 cells preincubated for 2 hrs followed by EGF stimulation for 10 mins by s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50210162(CHEMBL3883534)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of EGFR T790M/L858R double mutant phosphorylation in human H1975 cells preincubated for 2 hrs followed by EGF stimulation for 10 mins by s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50159360(CHEMBL3786098)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of EGFR T790M/exon 19 deletion mutant phosphorylation in human PC9-DRH cells preincubated for 2 hrs followed by EGF stimulation for 10 min...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50450869(CHEMBL4218154)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of EGFR T790M/L858R double mutant phosphorylation in human H1975 cells preincubated for 2 hrs followed by EGF stimulation for 10 mins by s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50450871(CHEMBL4205392)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of EGFR T790M/L858R double mutant phosphorylation in human H1975 cells preincubated for 2 hrs followed by EGF stimulation for 10 mins by s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50112173(CHEMBL3608429)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of EGFR exon 19 deletion mutant phosphorylation in human PC9 cells preincubated for 2 hrs followed by EGF stimulation for 10 mins by sandw...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM149404(AVL-301 | CHEMBL3545308 | CNX-419 | CO-1686 | Roci...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of EGFR T790M/exon 19 deletion mutant phosphorylation in human PC9-DRH cells preincubated for 2 hrs followed by EGF stimulation for 10 min...More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-3(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50112176(CHEMBL3608432)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of EGFR L858R mutant phosphorylation in human H3255 cells preincubated for 2 hrs followed by EGF stimulation for 10 mins by sandwich ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetReceptor tyrosine-protein kinase erbB-3(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of EGFR L858R mutant phosphorylation in human H3255 cells preincubated for 2 hrs followed by EGF stimulation for 10 mins by sandwich ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of EGFR exon 19 deletion mutant phosphorylation in human PC9 cells preincubated for 2 hrs followed by EGF stimulation for 10 mins by sandw...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of EGF-stimulated wild-type EGFR phosphorylation in human A549 cells preincubated for 2 hrs followed by EGF stimulation for 10 mins by san...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50450870(Mavelertinib | PF-06747775)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of EGFR T790M/L858R double mutant phosphorylation in human H1975 cells preincubated for 2 hrs followed by EGF stimulation for 10 mins by s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50450867(CHEMBL4206501)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of EGFR T790M/exon 19 deletion mutant phosphorylation in human PC9-DRH cells preincubated for 2 hrs followed by EGF stimulation for 10 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM50159360(CHEMBL3786098)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of EGFR T790M/L858R double mutant phosphorylation in human H1975 cells preincubated for 2 hrs followed by EGF stimulation for 10 mins by s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
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