Compile Data Set for Download or QSAR
Found 170 with Last Name = 'ismaili' and Initial = 'l'
TargetHistamine H3 receptor(Homo sapiens (Human))
Universit£ Bourgogne Franche-Comt£

Curated by ChEMBL
LigandPNGBDBM9019(CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...)copy SMILEScopy InChI
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human H3 receptor expressed in HEK293 cell membranes incubated for 60 mins by scintillation countin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736V9GPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Universit£ Bourgogne Franche-Comt£

Curated by ChEMBL
LigandPNGBDBM50519742(CHEMBL4469017)copy SMILEScopy InChI
Affinity DataKi:  40nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human H3 receptor expressed in HEK293 cell membranes incubated for 60 mins by scintillation countin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736V9GPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Universit£ Bourgogne Franche-Comt£

Curated by ChEMBL
LigandPNGBDBM50519739(CHEMBL4443523)copy SMILEScopy InChI
Affinity DataKi:  60nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human H3 receptor expressed in HEK293 cell membranes incubated for 60 mins by scintillation countin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736V9GPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Universit£ Bourgogne Franche-Comt£

Curated by ChEMBL
LigandPNGBDBM50519746(CHEMBL4455698)copy SMILEScopy InChI
Affinity DataKi:  83nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human H3 receptor expressed in HEK293 cell membranes incubated for 60 mins by scintillation countin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736V9GPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Laboratory of Medicinal Chemistry (IQOG, CSIC)

Curated by ChEMBL
LigandPNGBDBM50449738(CHEMBL4174958)copy SMILEScopy InChI
Affinity DataKi:  147nMAssay Description:Non-competitive inhibition of recombinant human AChE expressed in HEK293 cells assessed as enzyme-substrate-inhibitor complex using varying levels of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ06BWPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Universit£ Bourgogne Franche-Comt£

Curated by ChEMBL
LigandPNGBDBM50519740(CHEMBL4528980)copy SMILEScopy InChI
Affinity DataKi:  425nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human H3 receptor expressed in HEK293 cell membranes incubated for 60 mins by scintillation countin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736V9GPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Universit£ Bourgogne Franche-Comt£

Curated by ChEMBL
LigandPNGBDBM50519735(CHEMBL4573309)copy SMILEScopy InChI
Affinity DataKi:  565nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human H3 receptor expressed in HEK293 cell membranes incubated for 60 mins by scintillation countin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736V9GPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Laboratory of Medicinal Chemistry (IQOG, CSIC)

Curated by ChEMBL
LigandPNGBDBM50234769(CHEMBL4095908)copy SMILEScopy InChI
Affinity DataKi:  870nMAssay Description:Non-competitive inhibition of recombinant human AChE expressed in HEK293 cells using varying levels of acetylthiocholine iodide as substrate pretreat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6SR5PubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Universit£ Bourgogne Franche-Comt£

Curated by ChEMBL
LigandPNGBDBM50519745(CHEMBL4518949)copy SMILEScopy InChI
Affinity DataKi:  1.62E+3nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human H3 receptor expressed in HEK293 cell membranes incubated for 60 mins by scintillation countin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736V9GPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Laboratory of Medicinal Chemistry (IQOG, CSIC)

Curated by ChEMBL
LigandPNGBDBM50449745(CHEMBL4171520)copy SMILEScopy InChI
Affinity DataKi:  3.88E+3nMAssay Description:Non-competitive inhibition of recombinant human AChE expressed in HEK293 cells assessed as enzyme-substrate-inhibitor complex using varying levels of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ06BWPubMed
TargetCholinesterase(Equus caballus (Horse))
University of Sfax

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)copy SMILEScopy InChI
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of horse serum BuChE using butyrylthiocholine as substrate pretreated for 10 mins followed by substrate addition measured after 15 mins by...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50541071(CHEMBL4528766)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639T8FPubMed
TargetCholinesterase(Equus caballus (Horse))
University of Sfax

Curated by ChEMBL
LigandPNGBDBM50550232(CHEMBL4762083)copy SMILES
Affinity DataIC50: 1.30nMAssay Description:Inhibition of horse serum BuChE pre-incubated for 10 mins before addition of butyrylthiocholine iodide substrate and further incubated for 15 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WH2TMMPubMed
TargetCholinesterase(Equus caballus (Horse))
University of Sfax

Curated by ChEMBL
LigandPNGBDBM50550236(CHEMBL4759893)copy SMILES
Affinity DataIC50: 2.30nMAssay Description:Inhibition of horse serum BuChE pre-incubated for 10 mins before addition of butyrylthiocholine iodide substrate and further incubated for 15 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WH2TMMPubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50541069(CHEMBL4635389)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of rat MAO B using kynuramine as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639T8FPubMed
TargetCholinesterase(Equus caballus (Horse))
University of Sfax

Curated by ChEMBL
LigandPNGBDBM50550234(CHEMBL4784757)copy SMILES
Affinity DataIC50: 2.90nMAssay Description:Inhibition of horse serum BuChE pre-incubated for 10 mins before addition of butyrylthiocholine iodide substrate and further incubated for 15 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WH2TMMPubMed
TargetCholinesterase(Equus caballus (Horse))
University of Sfax

Curated by ChEMBL
LigandPNGBDBM50550235(CHEMBL4790426)copy SMILES
Affinity DataIC50: 3nMAssay Description:Inhibition of horse serum BuChE pre-incubated for 10 mins before addition of butyrylthiocholine iodide substrate and further incubated for 15 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WH2TMMPubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50550232(CHEMBL4762083)copy SMILES
Affinity DataIC50: 3.60nMAssay Description:Inhibition of Electrophorus electricus AChE pre-incubated for 10 mins before addition of acetylthiocholine iodide substrate and further incubated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WH2TMMPubMed
TargetCholinesterase(Equus caballus (Horse))
University of Sfax

Curated by ChEMBL
LigandPNGBDBM50550231(CHEMBL4752488)copy SMILES
Affinity DataIC50: 3.90nMAssay Description:Inhibition of horse serum BuChE pre-incubated for 10 mins before addition of butyrylthiocholine iodide substrate and further incubated for 15 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WH2TMMPubMed
TargetCholinesterase(Equus caballus (Horse))
University of Sfax

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)copy SMILEScopy InChI
Affinity DataIC50: 5.10nMAssay Description:Inhibition of horse serum BuChE pre-incubated for 10 mins before addition of butyrylthiocholine iodide substrate and further incubated for 15 mins by...More data for this Ligand-Target Pair
TargetCholinesterase(Equus caballus (Horse))
University of Sfax

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:Inhibition of horse serum BChE after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetCholinesterase(Equus caballus (Horse))
University of Sfax

Curated by ChEMBL
LigandPNGBDBM50550230(CHEMBL4761802)copy SMILES
Affinity DataIC50: 5.40nMAssay Description:Inhibition of horse serum BuChE pre-incubated for 10 mins before addition of butyrylthiocholine iodide substrate and further incubated for 15 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WH2TMMPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50359391(CHEMBL1929421)copy SMILEScopy InChI
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human MAO AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639T8FPubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50550230(CHEMBL4761802)copy SMILES
Affinity DataIC50: 7.60nMAssay Description:Inhibition of Electrophorus electricus AChE pre-incubated for 10 mins before addition of acetylthiocholine iodide substrate and further incubated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WH2TMMPubMed
TargetCholinesterase(Equus caballus (Horse))
University of Sfax

Curated by ChEMBL
LigandPNGBDBM50550229(CHEMBL4755679)copy SMILES
Affinity DataIC50: 8.20nMAssay Description:Inhibition of horse serum BuChE pre-incubated for 10 mins before addition of butyrylthiocholine iodide substrate and further incubated for 15 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WH2TMMPubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50550234(CHEMBL4784757)copy SMILES
Affinity DataIC50: 8.40nMAssay Description:Inhibition of Electrophorus electricus AChE pre-incubated for 10 mins before addition of acetylthiocholine iodide substrate and further incubated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WH2TMMPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Laboratory of Medicinal Chemistry (IQOG, CSIC)

Curated by ChEMBL
LigandPNGBDBM50541052(CHEMBL4632951)copy SMILEScopy InChI
Affinity DataIC50: 9.40nMAssay Description:Inhibition of human AChE using acetylthiocholine chloride as substrate peincubated for 15 mins followed by substrate addition measured at 1 min inter...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639T8FPubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50541052(CHEMBL4632951)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine chloride as substrate peincubated for 15 mins followed by substrate addition measured at 1 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639T8FPubMed
TargetCholinesterase(Equus caballus (Horse))
University of Sfax

Curated by ChEMBL
LigandPNGBDBM50550233(CHEMBL4762095)copy SMILES
Affinity DataIC50: 12nMAssay Description:Inhibition of horse serum BuChE pre-incubated for 10 mins before addition of butyrylthiocholine iodide substrate and further incubated for 15 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WH2TMMPubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50550236(CHEMBL4759893)copy SMILES
Affinity DataIC50: 14nMAssay Description:Inhibition of Electrophorus electricus AChE pre-incubated for 10 mins before addition of acetylthiocholine iodide substrate and further incubated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WH2TMMPubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50550229(CHEMBL4755679)copy SMILES
Affinity DataIC50: 15nMAssay Description:Inhibition of Electrophorus electricus AChE pre-incubated for 10 mins before addition of acetylthiocholine iodide substrate and further incubated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WH2TMMPubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50550231(CHEMBL4752488)copy SMILES
Affinity DataIC50: 16nMAssay Description:Inhibition of Electrophorus electricus AChE pre-incubated for 10 mins before addition of acetylthiocholine iodide substrate and further incubated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WH2TMMPubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50550235(CHEMBL4790426)copy SMILES
Affinity DataIC50: 18nMAssay Description:Inhibition of Electrophorus electricus AChE pre-incubated for 10 mins before addition of acetylthiocholine iodide substrate and further incubated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WH2TMMPubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Universit£ Bourgogne Franche-Comt£

Curated by ChEMBL
LigandPNGBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Antagonist activity at human H4 receptor expressed in CHO-K1 cells co-expressing G protein alpha16 assessed as inhibition of histamine-induced calciu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736V9GPubMed
TargetCholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50550236(CHEMBL4759893)copy SMILES
Affinity DataIC50: 24nMAssay Description:Inhibition of BuChE in human erythrocyte hemo-lyzates pre-incubated for 5 mins before addition of butyrylthiocholine iodide substrate by Ellman's met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WH2TMMPubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM8987(6-chloro-1,2,3,4-tetrahydroacridin-9-amine | 6-chl...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine chloride as substrate peincubated for 15 mins followed by substrate addition measured at 1 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639T8FPubMed
TargetCholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of BuChE in human erythrocyte hemo-lyzates pre-incubated for 5 mins before addition of butyrylthiocholine iodide substrate by Ellman's met...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of electric eel AChE after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ87X6PubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50550233(CHEMBL4762095)copy SMILES
Affinity DataIC50: 30nMAssay Description:Inhibition of Electrophorus electricus AChE pre-incubated for 10 mins before addition of acetylthiocholine iodide substrate and further incubated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WH2TMMPubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate pretreated for 10 mins followed by substrate addition measure...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6SR5PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Laboratory of Medicinal Chemistry (IQOG, CSIC)

Curated by ChEMBL
LigandPNGBDBM50449738(CHEMBL4174958)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of recombinant human AChE expressed in HEK293 cells using acetylthiocholine as substrate pretreated for 20 mins followed by substrate addi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ06BWPubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50234775(CHEMBL4103664)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate pretreated for 10 mins followed by substrate addition measure...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6SR5PubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50234769(CHEMBL4095908)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate pretreated for 10 mins followed by substrate addition measure...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6SR5PubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50234768(CHEMBL4085738)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate pretreated for 10 mins followed by substrate addition measure...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6SR5PubMed
TargetCholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant human serum BChE using butyrylthiocholine as substrate pretreated for 20 mins followed by substrate addition by Ellman's me...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Laboratory of Medicinal Chemistry (IQOG, CSIC)

Curated by ChEMBL
LigandPNGBDBM50550236(CHEMBL4759893)copy SMILES
Affinity DataIC50: 44nMAssay Description:Inhibition of AChE in human erythrocyte hemo-lyzates pre-incubated for 5 mins before addition of acetylthiocholine iodide substrate by Ellman's metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WH2TMMPubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of Electrophorus electricus AChE pre-incubated for 10 mins before addition of acetylthiocholine iodide substrate and further incubated for...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WH2TMMPubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine chloride as substrate peincubated for 15 mins followed by substrate addition measured at 1 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639T8FPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Laboratory of Medicinal Chemistry (IQOG, CSIC)

Curated by ChEMBL
LigandPNGBDBM50541051(CHEMBL4633540)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of human AChE using acetylthiocholine chloride as substrate peincubated for 15 mins followed by substrate addition measured at 1 min inter...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639T8FPubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50541051(CHEMBL4633540)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine chloride as substrate peincubated for 15 mins followed by substrate addition measured at 1 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639T8FPubMed
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