Compile Data Set for Download or QSAR
Found 296 with Last Name = 'leon' and Initial = 'l'
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50500145(CHEMBL1235987)copy SMILEScopy InChI
Affinity DataKi:  1.40nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6NC6PubMed
LigandPNGBDBM50384444(CHEMBL2035510)copy SMILEScopy InChI
Affinity DataKi:  3.16nMAssay Description:Antagonist activity at rat EP3 receptor expressed in human U2OS cells co-expressing Gqi5 assessed as inhibition of PGE2-induced response after 24 hrs...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2Q1FPubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384444(CHEMBL2035510)copy SMILEScopy InChI
Affinity DataKi:  3.16nMAssay Description:Antagonist activity at human EP3c receptor expressed in human U2OS cells assessed as inhibition of PGE2-induced calcium mobilization after 24 hrs by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2Q1FPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50219566(4-bromo-3-carboxymethoxy-5-[3-(1-phenylmethanesulf...)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384443(CHEMBL1770317)copy SMILEScopy InChI
Affinity DataKi:  5.01nMAssay Description:Binding affinity to human EP3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2Q1FPubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384445(CHEMBL2035508)copy SMILEScopy InChI
Affinity DataKi:  6.31nMAssay Description:Antagonist activity at human EP3c receptor expressed in human U2OS cells assessed as inhibition of PGE2-induced calcium mobilization after 24 hrs by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2Q1FPubMed
LigandPNGBDBM50384445(CHEMBL2035508)copy SMILEScopy InChI
Affinity DataKi:  7.94nMAssay Description:Antagonist activity at rat EP3 receptor expressed in human U2OS cells co-expressing Gqi5 assessed as inhibition of PGE2-induced response after 24 hrs...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2Q1FPubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384443(CHEMBL1770317)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Antagonist activity at human EP3c receptor expressed in human U2OS cells assessed as inhibition of PGE2-induced calcium mobilization after 24 hrs by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2Q1FPubMed
LigandPNGBDBM50384443(CHEMBL1770317)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Antagonist activity at rat EP3 receptor expressed in human U2OS cells co-expressing Gqi5 assessed as inhibition of PGE2-induced response after 24 hrs...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2Q1FPubMed
LigandPNGBDBM50384446(CHEMBL2035509)copy SMILEScopy InChI
Affinity DataKi:  12.6nMAssay Description:Antagonist activity at rat EP3 receptor expressed in human U2OS cells co-expressing Gqi5 assessed as inhibition of PGE2-induced response after 24 hrs...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2Q1FPubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384446(CHEMBL2035509)copy SMILEScopy InChI
Affinity DataKi:  19.9nMAssay Description:Antagonist activity at human EP3c receptor expressed in human U2OS cells assessed as inhibition of PGE2-induced calcium mobilization after 24 hrs by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2Q1FPubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384442(CHEMBL2035507)copy SMILEScopy InChI
Affinity DataKi:  200nMAssay Description:Antagonist activity at human EP3c receptor expressed in human U2OS cells assessed as inhibition of PGE2-induced calcium mobilization after 24 hrs by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2Q1FPubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Bristol

LigandPNGBDBM23232(1,2,5-oxadiazole, OXD1 | 4-hydroxy-1,2,5-oxadiazol...)copy SMILEScopy InChI
Affinity DataKi:  210nM ΔG°:  -38.1kJ/mole IC50: 650nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Bristol

LigandPNGBDBM23251(1,2,5-Thiadiazole, TDA1 | 4-hydroxy-1,2,5-thiadiaz...)copy SMILEScopy InChI
Affinity DataKi:  290nM ΔG°:  -37.3kJ/mole IC50: 140nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
LigandPNGBDBM50384442(CHEMBL2035507)copy SMILEScopy InChI
Affinity DataKi:  316nMAssay Description:Antagonist activity at rat EP3 receptor expressed in human U2OS cells co-expressing Gqi5 assessed as inhibition of PGE2-induced response after 24 hrs...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2Q1FPubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Bristol

LigandPNGBDBM23242(1,2(1,5)-Isoxazole, IOA1 | 3-hydroxy-1,2-oxazole-4...)copy SMILEScopy InChI
Affinity DataKi:  470nM ΔG°:  -36.1kJ/mole IC50: 1.10E+3nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384442(CHEMBL2035507)copy SMILEScopy InChI
Affinity DataKi: >5.01E+3nMAssay Description:Antagonist activity at EP1 receptor in human U2OS cells expressing Gqi5 assessed as inhibition of PGE2-induced response after 24 hrs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2Q1FPubMed
TargetGlucose-1-phosphate cytidylyltransferase(Salmonella typhi)
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50454133(CHEBI:17677 | Cystetine Triphosphate)copy SMILEScopy InChI
Affinity DataKi:  3.50E+4nMAssay Description:Binding affinity to Salmonella typhi glucose-1-phosphate cytidylyl-transferase assessed as dissociation constant by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6NC6PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384443(CHEMBL1770317)copy SMILEScopy InChI
Affinity DataKi: >5.01E+4nMAssay Description:Antagonist activity at EP1 receptor in human U2OS cells expressing Gqi5 assessed as inhibition of PGE2-induced response after 24 hrs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2Q1FPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50070228(2-(2-Mercapto-acetyl)-nonanoic acid ((S)-2,2-dimet...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:In vitro inhibitory activity against gelatinase-B(MMP-9).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W997QPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50070247(2-(2-Mercapto-acetyl)-nonanoic acid ((S)-2-cyclohe...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:In vitro inhibitory activity against gelatinase-B(MMP-9).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W997QPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50070227(2-(2-Mercapto-acetyl)-nonanoic acid ((S)-3-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:In vitro inhibitory activity against gelatinase-B(MMP-9).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W997QPubMed
TargetStromelysin-1(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50070250(2-(1-Hydroxy-2-mercapto-ethyl)-5-phenyl-pentanoic ...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:In vitro inhibitory activity against stromelysin-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W997QPubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50236304(1-(2-(5-bromo-2-(4-fluorophenyl)-1H-indol-3-yl)eth...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Antagonist activity at human cloned CXCR2 by calcium flux FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P10V3PubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50070226(2-(2-Mercapto-acetyl)-nonanoic acid {(S)-2-cyclohe...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:In vitro inhibitory activity against gelatinase-B(MMP-9).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W997QPubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50236292(4-[5-cyano-2-(4-fluorophenyl)-1H-indol-3-yl]-N-(di...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Antagonist activity at human cloned CXCR2 by calcium flux FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P10V3PubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50070223(2-(2-Mercapto-acetyl)-nonanoic acid ((S)-3-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:In vitro inhibitory activity against gelatinase-B(MMP-9).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W997QPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50070229(2-(2-Mercapto-acetyl)-4-methyl-pentanoic acid ((S)...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:In vitro inhibitory activity against gelatinase-B(MMP-9).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W997QPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50070239(2-(2-Mercapto-acetyl)-nonanoic acid [(S)-3-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:In vitro inhibitory activity against gelatinase-B(MMP-9).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W997QPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50500147(CHEMBL3746639)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6NC6PubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50070241(2-(2-Mercapto-acetyl)-nonanoic acid [(S)-1-(2-ethy...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:In vitro inhibitory activity against collagenase-1(MMP-1).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W997QPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50070235(2-(1-Hydroxy-2-mercapto-ethyl)-nonanoic acid [(S)-...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:In vitro inhibitory activity against collagenase-1(MMP-1).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W997QPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50070233(2-(1-Hydroxy-2-mercapto-ethyl)-nonanoic acid [(S)-...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:In vitro inhibitory activity against collagenase-1(MMP-1).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W997QPubMed
TargetStromelysin-1(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50070240(2-(2-Mercapto-acetyl)-nonanoic acid [(S)-1-(2-ethy...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:In vitro inhibitory activity against stromelysin-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W997QPubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50236295(4-[5-cyano-2-(4-fluorophenyl)-1H-indol-3-yl]-N-[(m...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Antagonist activity at human cloned CXCR2 by calcium flux FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P10V3PubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50070229(2-(2-Mercapto-acetyl)-4-methyl-pentanoic acid ((S)...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:In vitro inhibitory activity against collagenase-1(MMP-1).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W997QPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50070228(2-(2-Mercapto-acetyl)-nonanoic acid ((S)-2,2-dimet...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:In vitro inhibitory activity against collagenase-1(MMP-1).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W997QPubMed
TargetStromelysin-1(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50070228(2-(2-Mercapto-acetyl)-nonanoic acid ((S)-2,2-dimet...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:In vitro inhibitory activity against stromelysin-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W997QPubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50236312(4-(5-cyano-2-(4-fluorophenyl)-6-methyl-1H-indol-3-...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Displacement of europium labeled-human IL8 from human cloned CXCR2 expressed in Sf9 membrane with Galphai3-beta-1-gamma-2 by DELFIA binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P10V3PubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50070234(2-(2-Mercapto-acetyl)-4-methyl-pentanoic acid [(S)...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:In vitro inhibitory activity against gelatinase-B(MMP-9).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W997QPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50070223(2-(2-Mercapto-acetyl)-nonanoic acid ((S)-3-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:In vitro inhibitory activity against collagenase-1(MMP-1).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W997QPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50070244(2-(1-Hydroxy-2-mercapto-ethyl)-nonanoic acid [(S)-...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:In vitro inhibitory activity against collagenase-1(MMP-1).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W997QPubMed
TargetStromelysin-1(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50070225(2-(1-Hydroxy-2-mercapto-ethyl)-4-methyl-pentanoic ...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:In vitro inhibitory activity against stromelysin-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W997QPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50070230(2-(1-Hydroxy-2-mercapto-ethyl)-nonanoic acid ((S)-...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:In vitro inhibitory activity against collagenase-1(MMP-1).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W997QPubMed
TargetStromelysin-1(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50070236(2-(2-Mercapto-acetyl)-nonanoic acid {(S)-2,2-dimet...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:In vitro inhibitory activity against stromelysin-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W997QPubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50236318(4-[5-cyano-2-(4-fluorophenyl)-6-methyl-1H-indol-3-...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Displacement of europium labeled-human IL8 from human cloned CXCR2 expressed in Sf9 membrane with Galphai3-beta-1-gamma-2 by DELFIA binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P10V3PubMed
TargetStromelysin-1(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50070241(2-(2-Mercapto-acetyl)-nonanoic acid [(S)-1-(2-ethy...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:In vitro inhibitory activity against stromelysin-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W997QPubMed
TargetStromelysin-1(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50070242(2-(2-Mercapto-acetyl)-nonanoic acid [(S)-1-(2-ethy...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:In vitro inhibitory activity against stromelysin-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W997QPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50070241(2-(2-Mercapto-acetyl)-nonanoic acid [(S)-1-(2-ethy...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:In vitro inhibitory activity against gelatinase-B(MMP-9).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W997QPubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50236305(4-(5-cyano-2-(4-fluorophenyl)-1H-indol-3-yl)-N-(me...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Antagonist activity at human cloned CXCR2 by calcium flux FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P10V3PubMed
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