Found 120 with Last Name = 'morlock' and Initial = 'l' Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
National Institute of Biological Science
Curated by ChEMBL
National Institute of Biological Science
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of N-terminal His6-SUMO tagged recombinant human PDK2 using [32P]-gamma-ATP assessed as decrease in incorporation of radioactivity into E1...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
National Institute of Biological Science
Curated by ChEMBL
National Institute of Biological Science
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:Inhibition of N-terminal His6-SUMO tagged recombinant human PDK2 using [32P]-gamma-ATP assessed as decrease in incorporation of radioactivity into E1...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
National Institute of Biological Science
Curated by ChEMBL
National Institute of Biological Science
Curated by ChEMBL
Affinity DataIC50: 67nMAssay Description:Inhibition of N-terminal His6-SUMO tagged recombinant human PDK2 using [32P]-gamma-ATP assessed as decrease in incorporation of radioactivity into E1...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
National Institute of Biological Science
Curated by ChEMBL
National Institute of Biological Science
Curated by ChEMBL
Affinity DataIC50: 68nMAssay Description:Inhibition of N-terminal His6-SUMO tagged recombinant human PDK2 using [32P]-gamma-ATP assessed as decrease in incorporation of radioactivity into E1...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
National Institute of Biological Science
Curated by ChEMBL
National Institute of Biological Science
Curated by ChEMBL
Affinity DataIC50: 72nMAssay Description:Inhibition of N-terminal His6-SUMO tagged recombinant human PDK2 using [32P]-gamma-ATP assessed as decrease in incorporation of radioactivity into E1...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
National Institute of Biological Science
Curated by ChEMBL
National Institute of Biological Science
Curated by ChEMBL
Affinity DataIC50: 81nMAssay Description:Inhibition of N-terminal His6-SUMO tagged recombinant human PDK2 in presence of E1 protein and PDC core E2/E3BP incubated for 10 mins by titration as...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
National Institute of Biological Science
Curated by ChEMBL
National Institute of Biological Science
Curated by ChEMBL
Affinity DataIC50: 91nMAssay Description:Inhibition of N-terminal His6-SUMO tagged recombinant human PDK2 using [32P]-gamma-ATP assessed as decrease in incorporation of radioactivity into E1...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
National Institute of Biological Science
Curated by ChEMBL
National Institute of Biological Science
Curated by ChEMBL
Affinity DataIC50: 154nMAssay Description:Inhibition of N-terminal His6-SUMO tagged recombinant human PDK2 using [32P]-gamma-ATP assessed as decrease in incorporation of radioactivity into E1...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
National Institute of Biological Science
Curated by ChEMBL
National Institute of Biological Science
Curated by ChEMBL
Affinity DataIC50: 156nMAssay Description:Inhibition of N-terminal His6-SUMO tagged recombinant human PDK2 using [32P]-gamma-ATP assessed as decrease in incorporation of radioactivity into E1...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
National Institute of Biological Science
Curated by ChEMBL
National Institute of Biological Science
Curated by ChEMBL
Affinity DataIC50: 195nMAssay Description:Inhibition of N-terminal His6-SUMO tagged recombinant human PDK2 using [32P]-gamma-ATP assessed as decrease in incorporation of radioactivity into E1...More data for this Ligand-Target Pair
3D Structure (crystal)Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
National Institute of Biological Science
Curated by ChEMBL
National Institute of Biological Science
Curated by ChEMBL
Affinity DataIC50: 221nMAssay Description:Inhibition of N-terminal His6-SUMO tagged recombinant human PDK2 using [32P]-gamma-ATP assessed as decrease in incorporation of radioactivity into E1...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center
University of Texas Southwestern Medical Center
Affinity DataIC50: 280nMpH: 7.5 T: 2°CAssay Description:To determine the IC50 for PDK inhibitors, a mixture containing 0.05-0.2 μM PDK, 6μM E1, with or without 0.5 μM of the PDC core E2/E3BP...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center
University of Texas Southwestern Medical Center
Affinity DataIC50: 284nMAssay Description:Inhibition of recombinant human PDK4 in presence of E1 protein incubated for 10 mins by titration assayMore data for this Ligand-Target Pair
TargetTranslocator protein(Homo sapiens (Human))
University of Texas Southwestern Medical Center
Curated by ChEMBL
University of Texas Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
National Institute of Biological Science
Curated by ChEMBL
National Institute of Biological Science
Curated by ChEMBL
Affinity DataIC50: 357nMAssay Description:Inhibition of N-terminal His6-SUMO tagged recombinant human PDK2 using [32P]-gamma-ATP assessed as decrease in incorporation of radioactivity into E1...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
National Institute of Biological Science
Curated by ChEMBL
National Institute of Biological Science
Curated by ChEMBL
Affinity DataIC50: 416nMAssay Description:Inhibition of N-terminal His6-SUMO tagged recombinant human PDK2 using [32P]-gamma-ATP assessed as decrease in incorporation of radioactivity into E1...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center
University of Texas Southwestern Medical Center
Affinity DataIC50: 416nMAssay Description:Inhibition of recombinant human PDK4 in presence of E1 protein and PDC core E2/E3BP incubated for 10 mins by titration assayMore data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
National Institute of Biological Science
Curated by ChEMBL
National Institute of Biological Science
Curated by ChEMBL
Affinity DataIC50: 432nMAssay Description:Inhibition of N-terminal His6-SUMO tagged recombinant human PDK2 using [32P]-gamma-ATP assessed as decrease in incorporation of radioactivity into E1...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
National Institute of Biological Science
Curated by ChEMBL
National Institute of Biological Science
Curated by ChEMBL
Affinity DataIC50: 456nMAssay Description:Inhibition of N-terminal His6-SUMO tagged recombinant human PDK2 using [32P]-gamma-ATP assessed as decrease in incorporation of radioactivity into E1...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
National Institute of Biological Science
Curated by ChEMBL
National Institute of Biological Science
Curated by ChEMBL
Affinity DataIC50: 565nMAssay Description:Inhibition of N-terminal His6-SUMO tagged recombinant human PDK2 using [32P]-gamma-ATP assessed as decrease in incorporation of radioactivity into E1...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
National Institute of Biological Science
Curated by ChEMBL
National Institute of Biological Science
Curated by ChEMBL
Affinity DataIC50: 570nMAssay Description:Inhibition of N-terminal His6-SUMO tagged recombinant human PDK2 using [32P]-gamma-ATP assessed as decrease in incorporation of radioactivity into E1...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
National Institute of Biological Science
Curated by ChEMBL
National Institute of Biological Science
Curated by ChEMBL
Affinity DataIC50: 580nMAssay Description:Inhibition of N-terminal His6-SUMO tagged recombinant human PDK2 using [32P]-gamma-ATP assessed as decrease in incorporation of radioactivity into E1...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
National Institute of Biological Science
Curated by ChEMBL
National Institute of Biological Science
Curated by ChEMBL
Affinity DataIC50: 629nMAssay Description:Inhibition of N-terminal His6-SUMO tagged recombinant human PDK2 using [32P]-gamma-ATP assessed as decrease in incorporation of radioactivity into E1...More data for this Ligand-Target Pair
TargetTranslocator protein(Homo sapiens (Human))
University of Texas Southwestern Medical Center
Curated by ChEMBL
University of Texas Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 680nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
National Institute of Biological Science
Curated by ChEMBL
National Institute of Biological Science
Curated by ChEMBL
Affinity DataIC50: 710nMpH: 7.5 T: 2°CAssay Description:To determine the IC50 for PDK inhibitors, a mixture containing 0.05-0.2 μM PDK, 6μM E1, with or without 0.5 μM of the PDC core E2/E3BP...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
National Institute of Biological Science
Curated by ChEMBL
National Institute of Biological Science
Curated by ChEMBL
Affinity DataIC50: 767nMAssay Description:Inhibition of N-terminal His6-SUMO tagged recombinant human PDK2 using [32P]-gamma-ATP assessed as decrease in incorporation of radioactivity into E1...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center
University of Texas Southwestern Medical Center
Affinity DataIC50: 770nMpH: 7.5 T: 2°CAssay Description:To determine the IC50 for PDK inhibitors, a mixture containing 0.05-0.2 μM PDK, 6μM E1, with or without 0.5 μM of the PDC core E2/E3BP...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
National Institute of Biological Science
Curated by ChEMBL
National Institute of Biological Science
Curated by ChEMBL
Affinity DataIC50: 800nMpH: 7.5 T: 2°CAssay Description:To determine the IC50 for PDK inhibitors, a mixture containing 0.05-0.2 μM PDK, 6μM E1, with or without 0.5 μM of the PDC core E2/E3BP...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center
University of Texas Southwestern Medical Center
Affinity DataIC50: 840nMpH: 7.5 T: 2°CAssay Description:To determine the IC50 for PDK inhibitors, a mixture containing 0.05-0.2 μM PDK, 6μM E1, with or without 0.5 μM of the PDC core E2/E3BP...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center
University of Texas Southwestern Medical Center
Affinity DataIC50: 1.05E+3nMpH: 7.5 T: 2°CAssay Description:To determine the IC50 for PDK inhibitors, a mixture containing 0.05-0.2 μM PDK, 6μM E1, with or without 0.5 μM of the PDC core E2/E3BP...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
National Institute of Biological Science
Curated by ChEMBL
National Institute of Biological Science
Curated by ChEMBL
Affinity DataIC50: 1.07E+3nMpH: 7.5 T: 2°CAssay Description:To determine the IC50 for PDK inhibitors, a mixture containing 0.05-0.2 μM PDK, 6μM E1, with or without 0.5 μM of the PDC core E2/E3BP...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center
University of Texas Southwestern Medical Center
Affinity DataIC50: 1.10E+3nMpH: 7.5 T: 2°CAssay Description:To determine the IC50 for PDK inhibitors, a mixture containing 0.05-0.2 μM PDK, 6μM E1, with or without 0.5 μM of the PDC core E2/E3BP...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
National Institute of Biological Science
Curated by ChEMBL
National Institute of Biological Science
Curated by ChEMBL
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of N-terminal His6-SUMO tagged recombinant human PDK2 using [32P]-gamma-ATP assessed as decrease in incorporation of radioactivity into E1...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
National Institute of Biological Science
Curated by ChEMBL
National Institute of Biological Science
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of N-terminal His6-SUMO tagged recombinant human PDK2 using [32P]-gamma-ATP assessed as decrease in incorporation of radioactivity into E1...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
National Institute of Biological Science
Curated by ChEMBL
National Institute of Biological Science
Curated by ChEMBL
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of N-terminal His6-SUMO tagged recombinant human PDK2 using [32P]-gamma-ATP assessed as decrease in incorporation of radioactivity into E1...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
National Institute of Biological Science
Curated by ChEMBL
National Institute of Biological Science
Curated by ChEMBL
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of N-terminal His6-SUMO tagged recombinant human PDK2 using [32P]-gamma-ATP assessed as decrease in incorporation of radioactivity into E1...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
National Institute of Biological Science
Curated by ChEMBL
National Institute of Biological Science
Curated by ChEMBL
Affinity DataIC50: 1.61E+3nMAssay Description:Inhibition of N-terminal His6-SUMO tagged recombinant human PDK2 using [32P]-gamma-ATP assessed as decrease in incorporation of radioactivity into E1...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
National Institute of Biological Science
Curated by ChEMBL
National Institute of Biological Science
Curated by ChEMBL
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of N-terminal His6-SUMO tagged recombinant human PDK2 using [32P]-gamma-ATP assessed as decrease in incorporation of radioactivity into E1...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial(Homo sapiens (Human))
National Institute of Biological Science
Curated by ChEMBL
National Institute of Biological Science
Curated by ChEMBL
Affinity DataIC50: 1.71E+3nMAssay Description:Inhibition of recombinant human PDK3 in presence of E1 protein and PDC core E2/E3BP incubated for 10 mins by titration assayMore data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center
University of Texas Southwestern Medical Center
Affinity DataIC50: 1.86E+3nMpH: 7.5 T: 2°CAssay Description:To determine the IC50 for PDK inhibitors, a mixture containing 0.05-0.2 μM PDK, 6μM E1, with or without 0.5 μM of the PDC core E2/E3BP...More data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
University of Texas Southwestern Medical Center
Curated by ChEMBL
University of Texas Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
TargetTranslocator protein(Homo sapiens (Human))
University of Texas Southwestern Medical Center
Curated by ChEMBL
University of Texas Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
National Institute of Biological Science
Curated by ChEMBL
National Institute of Biological Science
Curated by ChEMBL
Affinity DataIC50: 2.06E+3nMAssay Description:Inhibition of recombinant human PDK1 in presence of E1 protein and PDC core E2/E3BP incubated for 10 mins by titration assayMore data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
National Institute of Biological Science
Curated by ChEMBL
National Institute of Biological Science
Curated by ChEMBL
Affinity DataIC50: 2.07E+3nMpH: 7.5 T: 2°CAssay Description:To determine the IC50 for PDK inhibitors, a mixture containing 0.05-0.2 μM PDK, 6μM E1, with or without 0.5 μM of the PDC core E2/E3BP...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
National Institute of Biological Science
Curated by ChEMBL
National Institute of Biological Science
Curated by ChEMBL
Affinity DataIC50: 2.11E+3nMpH: 7.5 T: 2°CAssay Description:To determine the IC50 for PDK inhibitors, a mixture containing 0.05-0.2 μM PDK, 6μM E1, with or without 0.5 μM of the PDC core E2/E3BP...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
National Institute of Biological Science
Curated by ChEMBL
National Institute of Biological Science
Curated by ChEMBL
Affinity DataIC50: 2.14E+3nMpH: 7.5 T: 2°CAssay Description:To determine the IC50 for PDK inhibitors, a mixture containing 0.05-0.2 μM PDK, 6μM E1, with or without 0.5 μM of the PDC core E2/E3BP...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center
University of Texas Southwestern Medical Center
Affinity DataIC50: 2.20E+3nMpH: 7.5 T: 2°CAssay Description:To determine the IC50 for PDK inhibitors, a mixture containing 0.05-0.2 μM PDK, 6μM E1, with or without 0.5 μM of the PDC core E2/E3BP...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
National Institute of Biological Science
Curated by ChEMBL
National Institute of Biological Science
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMpH: 7.5 T: 2°CAssay Description:To determine the IC50 for PDK inhibitors, a mixture containing 0.05-0.2 μM PDK, 6μM E1, with or without 0.5 μM of the PDC core E2/E3BP...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
National Institute of Biological Science
Curated by ChEMBL
National Institute of Biological Science
Curated by ChEMBL
Affinity DataIC50: 2.54E+3nMAssay Description:Inhibition of recombinant human PDK1 in presence of E1 protein incubated for 10 mins by titration assayMore data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial(Homo sapiens (Human))
National Institute of Biological Science
Curated by ChEMBL
National Institute of Biological Science
Curated by ChEMBL
Affinity DataIC50: 2.55E+3nMpH: 7.5 T: 2°CAssay Description:To determine the IC50 for PDK inhibitors, a mixture containing 0.05-0.2 μM PDK, 6μM E1, with or without 0.5 μM of the PDC core E2/E3BP...More data for this Ligand-Target Pair
