Compile Data Set for Download or QSAR
Found 26 with Last Name = 'sower' and Initial = 'l'
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50262712(3-[(9-oxo-9Hfluorene-1-carbonyl)-amino]-benzoic ac...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Bacillus anthracis edema factor-induced cytotoxicity in mouse RAW264.7 cells assessed as LDH release after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R2116MPubMed
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50262713(4-(3-methoxy-phenyl)-3a,4,5,9b-tetrahydro-3H-cyclo...)copy SMILEScopy InChI
Affinity DataIC50: 1.73E+3nMAssay Description:Inhibition of Bacillus anthracis edema factor-induced cAMP secretion in mouse RAW264.7 cells after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R2116MPubMed
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50262713(4-(3-methoxy-phenyl)-3a,4,5,9b-tetrahydro-3H-cyclo...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of Bacillus anthracis edema factor-induced cytotoxicity in mouse RAW264.7 cells assessed as LDH release after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R2116MPubMed
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50262712(3-[(9-oxo-9Hfluorene-1-carbonyl)-amino]-benzoic ac...)copy SMILEScopy InChI
Affinity DataIC50: 1.83E+3nMAssay Description:Inhibition of Bacillus anthracis edema factor-induced cAMP secretion in mouse RAW264.7 cells after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R2116MPubMed
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50262711(4-[(anthracen-9-ylmethylene)-amino]-2-hydroxy-benz...)copy SMILEScopy InChI
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of Bacillus anthracis edema factor-induced cAMP secretion in mouse RAW264.7 cells after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R2116MPubMed
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50262711(4-[(anthracen-9-ylmethylene)-amino]-2-hydroxy-benz...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of Bacillus anthracis edema factor-induced cytotoxicity in mouse RAW264.7 cells assessed as LDH release after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R2116MPubMed
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50243831(3-(6-methoxypyridin-3-yl)-2-methylcyclopent-2-enon...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of Bacilus anthracis edema factor-induced edema in RAW264.7 mouse macrophages by cAMP-specific ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MMNPubMed
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50243793(3-(6-methoxypyridin-2-yl)-2-methylcyclopent-2-enon...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Bacilus anthracis edema factor-induced edema in RAW264.7 mouse macrophages by cAMP-specific ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MMNPubMed
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50243832(3-(3-methoxyphenyl)cyclohex-2-enone | CHEMBL507392)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Bacilus anthracis edema factor-induced edema in RAW264.7 mouse macrophages by cAMP-specific ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MMNPubMed
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50243836(3-(2-methoxyphenyl)cyclohex-2-enone | CHEMBL486251)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of Bacilus anthracis edema factor-induced edema in RAW264.7 mouse macrophages by cAMP-specific ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MMNPubMed
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50243790(3-(benzo[d][1,3]dioxol-5-yl)cyclohex-2-enone | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of Bacilus anthracis edema factor-induced edema in RAW264.7 mouse macrophages by cAMP-specific ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MMNPubMed
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50243834(3-(1H-indol-5-yl)cyclohex-2-enone | CHEMBL449336)copy SMILEScopy InChI
Affinity DataIC50: 5.60E+4nMAssay Description:Inhibition of Bacilus anthracis edema factor-induced edema in RAW264.7 mouse macrophages by cAMP-specific ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MMNPubMed
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50243828(3-(thiophen-3-yl)cyclohex-2-enone | CHEMBL474875)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Bacilus anthracis edema factor-induced edema in RAW264.7 mouse macrophages by cAMP-specific ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MMNPubMed
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50243829(3-(thiophen-2-yl)cyclohex-2-enone | CHEMBL451060)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Bacilus anthracis edema factor-induced edema in RAW264.7 mouse macrophages by cAMP-specific ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MMNPubMed
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50243787(3-phenylcyclohex-2-enone | CHEMBL503170)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Bacilus anthracis edema factor-induced edema in RAW264.7 mouse macrophages by cAMP-specific ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MMNPubMed
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50243835(3-Dibenzofuran-4-yl-5,5-dimethyl-cyclohex-2-enone ...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Bacilus anthracis edema factor-induced edema in RAW264.7 mouse macrophages by cAMP-specific ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MMNPubMed
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50243792(3-(1H-indol-5-yl)-5,5-dimethylcyclohex-2-enone | C...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Bacilus anthracis edema factor-induced edema in RAW264.7 mouse macrophages by cAMP-specific ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MMNPubMed
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50243791(3-(3-hydroxyphenyl)cyclohex-2-enone | CHEMBL488651)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Bacilus anthracis edema factor-induced edema in RAW264.7 mouse macrophages by cAMP-specific ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MMNPubMed
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50243833(3-(quinolin-6-yl)cyclohex-2-enone | CHEMBL442887)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Bacilus anthracis edema factor-induced edema in RAW264.7 mouse macrophages by cAMP-specific ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MMNPubMed
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50243830(3-(furan-3-yl)cyclohex-2-enone | CHEMBL486250)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Bacilus anthracis edema factor-induced edema in RAW264.7 mouse macrophages by cAMP-specific ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MMNPubMed
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50262663((3aS,4S,9bR)-4-(4-(methoxycarbonyl)phenyl)-3a,4,5,...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Bacillus anthracis edema factor-induced cytotoxicity in mouse RAW264.7 cells assessed as LDH release after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R2116MPubMed
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50243827(3-(thiazol-2-yl)cyclohex-2-enone | CHEMBL504660)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Bacilus anthracis edema factor-induced edema in RAW264.7 mouse macrophages by cAMP-specific ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MMNPubMed
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50243826(3-(6-methoxypyridin-2-yl)cyclohex-2-enone | CHEMBL...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Bacilus anthracis edema factor-induced edema in RAW264.7 mouse macrophages by cAMP-specific ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MMNPubMed
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50243788(3-(pyridin-3-yl)cyclohex-2-enone | CHEMBL453229)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Bacilus anthracis edema factor-induced edema in RAW264.7 mouse macrophages by cAMP-specific ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MMNPubMed
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50243789(3-Dibenzofuran-4-yl-cyclohex-2-enone | CHEMBL48862...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Bacilus anthracis edema factor-induced edema in RAW264.7 mouse macrophages by cAMP-specific ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MMNPubMed
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50243825(3-(1-methyl-1H-pyrazol-4-yl)cyclohex-2-enone | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Bacilus anthracis edema factor-induced edema in RAW264.7 mouse macrophages by cAMP-specific ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MMNPubMed