Compile Data Set for Download or QSAR
Found 84 with Last Name = 'castonguay' and Initial = 'la'
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105372((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-2-met...)copy SMILEScopy InChI
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of Mn2+ activated state of very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN15PMPubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50373120(CHEMBL260977 | MK-0364)copy SMILEScopy InChI
Affinity DataIC50: 0.0940nMAssay Description:Displacement of [3H]SR-141716 from human wild type CB1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KDRPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105372((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-2-met...)copy SMILEScopy InChI
Affinity DataIC50: 0.270nMAssay Description:Inhibition of [Ca2+]/Mg2+ unactivated state of very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN15PMPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144790((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-azeti...)copy SMILEScopy InChI
Affinity DataIC50: 0.270nMAssay Description:Inhibition of Mn2+ activated state of very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN15PMPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144790((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-azeti...)copy SMILEScopy InChI
Affinity DataIC50: 0.310nMAssay Description:Inhibition of [Ca2+]/Mg2+ unactivated state of very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN15PMPubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM21279(1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N...)copy SMILEScopy InChI
Affinity DataIC50: 0.320nMAssay Description:Displacement of [3H]SR-141716 from human wild type CB1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KDRPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144791((S)-3-[2-(2,6-Dichloro-phenyl)-benzooxazol-5-yl]-2...)copy SMILEScopy InChI
Affinity DataIC50: 0.340nMAssay Description:Inhibition of Mn2+ activated state of very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN15PMPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144786((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-azeti...)copy SMILEScopy InChI
Affinity DataIC50: 0.540nMAssay Description:Inhibition of Mn2+ activated state of very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN15PMPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144792((S)-2-(2,6-Dichloro-benzoylamino)-3-[2-(2,6-dichlo...)copy SMILEScopy InChI
Affinity DataIC50: 0.690nMAssay Description:Inhibition of Mn2+ activated state of very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN15PMPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144789((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-azeti...)copy SMILEScopy InChI
Affinity DataIC50: 0.740nMAssay Description:Inhibition of Mn2+ activated state of very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN15PMPubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50373120(CHEMBL260977 | MK-0364)copy SMILEScopy InChI
Affinity DataIC50: 0.740nMAssay Description:Displacement of [3H]CP-55940 from human wild type CB1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KDRPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144787((S)-2-(2,6-Dichloro-benzoylamino)-3-[2-(2,6-dichlo...)copy SMILEScopy InChI
Affinity DataIC50: 0.790nMAssay Description:Inhibition of Mn2+ activated state of very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN15PMPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144788((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-azeti...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Mn2+ activated state of very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN15PMPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144786((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-azeti...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of [Ca2+]/Mg2+ unactivated state of very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN15PMPubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144792((S)-2-(2,6-Dichloro-benzoylamino)-3-[2-(2,6-dichlo...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of Mn2+ activated state of alpha4-beta7 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN15PMPubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM21279(1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Displacement of [3H]CP-55940 from human wild type CB1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KDRPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144789((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-azeti...)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Inhibition of [Ca2+]/Mg2+ unactivated state of very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN15PMPubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144791((S)-3-[2-(2,6-Dichloro-phenyl)-benzooxazol-5-yl]-2...)copy SMILEScopy InChI
Affinity DataIC50: 4.30nMAssay Description:Inhibition of Mn2+ activated state of alpha4-beta7 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN15PMPubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144787((S)-2-(2,6-Dichloro-benzoylamino)-3-[2-(2,6-dichlo...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Inhibition of Mn2+ activated state of alpha4-beta7 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN15PMPubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105372((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-2-met...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of Mn2+ activated state of alpha4-beta7 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN15PMPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144791((S)-3-[2-(2,6-Dichloro-phenyl)-benzooxazol-5-yl]-2...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of [Ca2+]/Mg2+ unactivated state of very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN15PMPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144792((S)-2-(2,6-Dichloro-benzoylamino)-3-[2-(2,6-dichlo...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of [Ca2+]/Mg2+ unactivated state of very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN15PMPubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144790((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-azeti...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of Mn2+ activated state of alpha4-beta7 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN15PMPubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Sanofi Winthrop Inc.

Curated by ChEMBL
LigandPNGBDBM50030498(CHEMBL53841 | [1-Benzyl-7-chloro-1H-quinolin-(4E)-...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Concentration inhibiting [125I]-ChTX (charybdotoxin) binding to N-type potassium channel.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WSJPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144788((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-azeti...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of [Ca2+]/Mg2+ unactivated state of very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN15PMPubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Sanofi Winthrop Inc.

Curated by ChEMBL
LigandPNGBDBM50030511(CHEMBL293721 | [1-Benzyl-6-methoxy-1H-quinolin-(4E...)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Concentration inhibiting [125I]-ChTX (charybdotoxin) binding to N-type potassium channel.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WSJPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144787((S)-2-(2,6-Dichloro-benzoylamino)-3-[2-(2,6-dichlo...)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of [Ca2+]/Mg2+ unactivated state of very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN15PMPubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Sanofi Winthrop Inc.

Curated by ChEMBL
LigandPNGBDBM50030510(CHEMBL299668 | [1-Benzyl-7-chloro-1H-quinolin-(4E)...)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Concentration inhibiting [125I]-ChTX (charybdotoxin) binding to N-type potassium channel.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WSJPubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Sanofi Winthrop Inc.

Curated by ChEMBL
LigandPNGBDBM50030505(CHEMBL56589 | [7-Chloro-1-naphthalen-2-yl-1H-quino...)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Concentration inhibiting [125I]-ChTX (charybdotoxin) binding to N-type potassium channel.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WSJPubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Sanofi Winthrop Inc.

Curated by ChEMBL
LigandPNGBDBM50030495(CHEMBL55202 | [7-Chloro-1-(4-methoxy-benzyl)-1H-qu...)copy SMILEScopy InChI
Affinity DataIC50: 88nMAssay Description:Concentration inhibiting [125I]-ChTX (charybdotoxin) binding to N-type potassium channel.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WSJPubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Sanofi Winthrop Inc.

Curated by ChEMBL
LigandPNGBDBM50030499(CHEMBL56998 | [7-Chloro-1-(4-chloro-benzyl)-1H-qui...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Concentration inhibiting [125I]-ChTX (charybdotoxin) binding to N-type potassium channel.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WSJPubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144786((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-azeti...)copy SMILEScopy InChI
Affinity DataIC50: 105nMAssay Description:Inhibition of Mn2+ activated state of alpha4-beta7 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN15PMPubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Sanofi Winthrop Inc.

Curated by ChEMBL
LigandPNGBDBM50030508(CHEMBL54934 | [1-Benzyl-7-chloro-1H-quinolin-(4E)-...)copy SMILEScopy InChI
Affinity DataIC50: 117nMAssay Description:Concentration inhibiting [125I]-ChTX (charybdotoxin) binding to N-type potassium channel.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WSJPubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Sanofi Winthrop Inc.

Curated by ChEMBL
LigandPNGBDBM50030521(CHEMBL56173 | [1-Benzyl-1H-quinolin-(4E)-ylidene]-...)copy SMILEScopy InChI
Affinity DataIC50: 164nMAssay Description:Concentration inhibiting [125I]-ChTX (charybdotoxin) binding to N-type potassium channel.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WSJPubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144789((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-azeti...)copy SMILEScopy InChI
Affinity DataIC50: 179nMAssay Description:Inhibition of Mn2+ activated state of alpha4-beta7 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN15PMPubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Sanofi Winthrop Inc.

Curated by ChEMBL
LigandPNGBDBM50030497(CHEMBL298622 | [7-Chloro-1-(2-chloro-benzyl)-1H-qu...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Concentration inhibiting [125I]-ChTX (charybdotoxin) binding to N-type potassium channel.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WSJPubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Sanofi Winthrop Inc.

Curated by ChEMBL
LigandPNGBDBM50030500(CHEMBL293083 | [1-Benzyl-7-chloro-1H-quinolin-(4E)...)copy SMILEScopy InChI
Affinity DataIC50: 198nMAssay Description:Concentration inhibiting [125I]-ChTX (charybdotoxin) binding to N-type potassium channel.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WSJPubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Sanofi Winthrop Inc.

Curated by ChEMBL
LigandPNGBDBM50030528(CHEMBL291738 | [1-Benzyl-7-chloro-1H-quinolin-(4E)...)copy SMILEScopy InChI
Affinity DataIC50: 206nMAssay Description:Concentration inhibiting [125I]-ChTX (charybdotoxin) binding to N-type potassium channel.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WSJPubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Sanofi Winthrop Inc.

Curated by ChEMBL
LigandPNGBDBM50030496(CHEMBL416313 | [1-(4-Chloro-benzyl)-6-trifluoromet...)copy SMILEScopy InChI
Affinity DataIC50: 213nMAssay Description:Inhibition of outward potassium currents (IKn) in human T-lymphocyte N-type potassium channels.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WSJPubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Sanofi Winthrop Inc.

Curated by ChEMBL
LigandPNGBDBM50030497(CHEMBL298622 | [7-Chloro-1-(2-chloro-benzyl)-1H-qu...)copy SMILEScopy InChI
Affinity DataIC50: 216nMAssay Description:Inhibition of outward potassium currents (IKn) in human T-lymphocyte N-type potassium channels.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WSJPubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Sanofi Winthrop Inc.

Curated by ChEMBL
LigandPNGBDBM50030523(CHEMBL294373 | [1-(4-Chloro-benzyl)-8-fluoro-1H-qu...)copy SMILEScopy InChI
Affinity DataIC50: 227nMAssay Description:Concentration inhibiting [125I]-ChTX (charybdotoxin) binding to N-type potassium channel.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WSJPubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Sanofi Winthrop Inc.

Curated by ChEMBL
LigandPNGBDBM50030519(CHEMBL53676 | [7-Chloro-1-(3,4-dichloro-benzyl)-1H...)copy SMILEScopy InChI
Affinity DataIC50: 231nMAssay Description:Inhibition of outward potassium currents (IKn) in human T-lymphocyte N-type potassium channels.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WSJPubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Sanofi Winthrop Inc.

Curated by ChEMBL
LigandPNGBDBM50030502(CHEMBL299451 | [1-(4-Chloro-benzyl)-7-trifluoromet...)copy SMILEScopy InChI
Affinity DataIC50: 239nMAssay Description:Concentration inhibiting [125I]-ChTX (charybdotoxin) binding to N-type potassium channel.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WSJPubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Sanofi Winthrop Inc.

Curated by ChEMBL
LigandPNGBDBM50030509(CHEMBL59308 | Methanesulfonate4-hexylamino-1-methy...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Concentration inhibiting [125I]-ChTX (charybdotoxin) binding to N-type potassium channel.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WSJPubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Sanofi Winthrop Inc.

Curated by ChEMBL
LigandPNGBDBM50030515(CHEMBL55142 | Methanesulfonate4-hexylamino-6-metho...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Concentration inhibiting [125I]-ChTX (charybdotoxin) binding to N-type potassium channel.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WSJPubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Sanofi Winthrop Inc.

Curated by ChEMBL
LigandPNGBDBM50030508(CHEMBL54934 | [1-Benzyl-7-chloro-1H-quinolin-(4E)-...)copy SMILEScopy InChI
Affinity DataIC50: 249nMAssay Description:Inhibition of outward potassium currents (IKn) in human T-lymphocyte N-type potassium channels.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WSJPubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Sanofi Winthrop Inc.

Curated by ChEMBL
LigandPNGBDBM50030510(CHEMBL299668 | [1-Benzyl-7-chloro-1H-quinolin-(4E)...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of outward potassium currents (IKn) in human T-lymphocyte N-type potassium channels.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WSJPubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Sanofi Winthrop Inc.

Curated by ChEMBL
LigandPNGBDBM50030516(CHEMBL54846 | [7-Chloro-1-(2-chloro-benzyl)-1H-qui...)copy SMILEScopy InChI
Affinity DataIC50: 259nMAssay Description:Inhibition of outward potassium currents (IKn) in human T-lymphocyte N-type potassium channels.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WSJPubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Sanofi Winthrop Inc.

Curated by ChEMBL
LigandPNGBDBM50030511(CHEMBL293721 | [1-Benzyl-6-methoxy-1H-quinolin-(4E...)copy SMILEScopy InChI
Affinity DataIC50: 267nMAssay Description:Inhibition of outward potassium currents (IKn) in human T-lymphocyte N-type potassium channels.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WSJPubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Sanofi Winthrop Inc.

Curated by ChEMBL
LigandPNGBDBM50030524(CHEMBL417417 | [1-(4-Chloro-benzyl)-6-methoxy-1H-q...)copy SMILEScopy InChI
Affinity DataIC50: 275nMAssay Description:Concentration inhibiting [125I]-ChTX (charybdotoxin) binding to N-type potassium channel.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WSJPubMed
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